{"id":26429,"date":"2021-04-13T21:07:00","date_gmt":"2021-04-13T14:07:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021041321070026429"},"modified":"2021-04-14T21:38:16","modified_gmt":"2021-04-14T13:38:16","slug":"%e7%a7%91%e5%ad%a6%e8%87%b4%e8%83%9c%ef%bc%8c%e8%be%89%e7%91%9e%e7%aa%81%e7%a0%b4%e6%80%a7%e5%88%9b%e6%96%b0%e4%ba%a7%e5%93%81%e5%86%8d%e5%ba%a6%e4%ba%ae%e7%9b%b8%e8%8d%af%e6%a2%b0%e5%b1%95","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021041321070026429","title":{"rendered":"\u79d1\u5b66\u81f4\u80dc\uff0c\u8f89\u745e\u7a81\u7834\u6027\u521b\u65b0\u4ea7\u54c1\u518d\u5ea6\u4eae\u76f8\u836f\u68b0\u5c55"},"content":{"rendered":"<p><p><span class=\"xn-subheadline\">&#8212; \u7b2c\u4e8c\u671f\u5065\u5eb7\u6d77\u5357-\u4e50\u57ce\u884c\u66a8\u201c\u6c38\u4e0d\u843d\u5e55\u201d\u56fd\u9645\u836f\u68b0\u5c55\u6b63\u5f0f\u5f00\u5e55<\/span><\/p>\n<p><span class=\"xn-subheadline\">&#8212; \u521b\u65b0\u52a9\u529b\u5065\u5eb7\u4e2d\u56fd\uff0c\u8f89\u745e\u8363\u83b7\u201c\u6700\u4f73\u5408\u4f5c\u4f19\u4f34\u5956\u201d<\/span><\/p>\n<p>\u6d77\u5357\u535a\u9ccc2021\u5e744\u670813\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 4\u670813\u65e5\uff0c\u7531\u6d77\u5357\u7701\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\uff08\u4ee5\u4e0b\u7b80\u79f0\u4e50\u57ce\u5148\u884c\u533a\uff09\u7ba1\u7406\u5c40\u4e3b\u529e\u7684\u7b2c\u4e8c\u671f\u5065\u5eb7\u6d77\u5357-\u4e50\u57ce\u884c\u66a8\u201c\u6c38\u4e0d\u843d\u5e55\u201d\u56fd\u9645\u836f\u68b0\u5c55\u5728\u535a\u9ccc\u5982\u671f\u4e3e\u884c\u3002\u4f5c\u4e3a\u53c2\u4e0e\u7b2c\u4e00\u671f\u836f\u68b0\u5c55\u7684\u91cd\u70b9\u5382\u5546\uff0c\u8f89\u745e\u4e0d\u4ec5\u518d\u5ea6\u643a\u4e94\u5927\u9886\u57df\u591a\u79cd\u6cbb\u7597\u65b9\u6848\u4eae\u76f8\uff0c\u5411\u4e0e\u4f1a\u8005\u5c55\u793a\u4e86\u8f89\u745e\u5df2\u4e0a\u5e02\u53ca\u5728\u7814\u7684\u521b\u65b0\u4ea7\u54c1\uff0c\u540c\u65f6\u8363\u83b7\u4e86\u4e50\u57ce\u5148\u884c\u533a\u7ba1\u7406\u5c40\u9881\u53d1\u7684\u201c\u6700\u4f73\u5408\u4f5c\u4f19\u4f34\u5956\u201d\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">\n<p> <a href=\"https:\/\/mma.prnasia.com\/media2\/1486680\/image.html\" target=\"_blank\" rel=\"nofollow noopener\"> <img decoding=\"async\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/image-257.jpg\" title=\"\" alt=\"\" \/> <\/a> <br \/><span><\/span><\/p>\n<\/p><\/div>\n<p><b>\u8d21\u732e\u521b\u65b0\u667a\u6167\uff0c\u505a\u5065\u5eb7\u4e2d\u56fd\u7684<\/b><b>\u201c<\/b><b>\u6700\u4f73\u5408\u4f5c\u4f19\u4f34<\/b><b>\u201d<\/b><\/p>\n<p>\u201c\u6c38\u4e0d\u843d\u5e55\u201d\u56fd\u9645\u521b\u65b0\u836f\u68b0\u5c55\uff0c\u65e2\u662f\u4e50\u57ce\u5148\u884c\u533a\u52a0\u5feb\u53d1\u5c55\u7684\u4e00\u4e2a\u7f29\u5f71\uff0c\u4e5f\u662f\u52a9\u529b\u8de8\u56fd\u836f\u4f01\u5c06\u672a\u5728\u56fd\u5185\u4e0a\u5e02\u7684\u521b\u65b0\u836f\u68b0\u52a0\u901f\u843d\u5730\u4e2d\u56fd\u7684\u91cd\u8981\u7a97\u53e3\u3002<\/p>\n<p><i>\u4e50\u57ce\u5148\u884c\u533a\u7ba1\u7406\u5c40\u515a\u59d4\u4e66\u8bb0\u3001\u5c40\u957f\u987e\u521a\u8868\u793a\uff1a\u201c\u53bb\u5e74\uff0c\u5728\u7701\u59d4\u3001\u7701\u653f\u5e9c\u9886\u5bfc\u4e0e\u591a\u804c\u80fd\u90e8\u95e8\u7684\u5171\u540c\u52aa\u529b\u4e0b\uff0c\u5728\u4f17\u591a\u836f\u68b0\u4f01\u4e1a\u7684\u652f\u6301\u4e0b\uff0c\u7b2c\u4e00\u671f\u5c55\u4f1a\u83b7\u5f97\u4e86\u5706\u6ee1\u7684\u6210\u6548\uff0c\u4e5f\u8ba9\u5927\u5bb6\u770b\u5230\u4e86\u4e50\u57ce\u96c6\u6210\u521b\u65b0\u7684\u53d1\u5c55\u52bf\u5934\u3002\u4eca\u5e74\u7b2c\u4e8c\u671f\uff0c\u975e\u5e38\u9ad8\u5174\u770b\u5230\u5305\u62ec\u8f89\u745e\u5728\u5185\u7684\u5168\u7403\u5353\u8d8a\u836f\u4f01\u7ee7\u7eed\u4e3a\u4e2d\u56fd\u5927\u4f17\u5e26\u6765\u4e86\u521b\u65b0\u4ea7\u54c1\u53ca\u6cbb\u7597\u65b9\u6848\uff0c\u4e3a\u5065\u5eb7\u4e2d\u56fd\u8d21\u732e\u521b\u65b0\u667a\u6167\u3002\u4e0b\u4e00\u6b65\uff0c\u4e50\u57ce\u5148\u884c\u533a\u5c06\u6301\u7eed\u4e0d\u65ad\u4f18\u5316\u8425\u5546\u73af\u5883\uff0c\u8ba9\u66f4\u591a\u7684\u836f\u68b0\u5382\u5546\u548c\u56ed\u533a\u4f01\u4e1a\u80fd\u591f\u4eab\u53d7\u5230\u6d77\u5357\u81ea\u8d38\u6e2f\u7684\u7ea2\u5229\u3001\u4e50\u57ce\u7684\u7ea2\u5229\u3002\u201d<\/i><i>&nbsp;<\/i><\/p>\n<p>\u51ed\u501f\u836f\u68b0\u5c55\u7684\u5927\u821e\u53f0\uff0c\u8f89\u745e\u53bb\u5e74\u5c55\u793a\u7684\u521b\u65b0\u836f\u5f97\u4ee5\u5feb\u901f\u5f15\u5165\u4e2d\u56fd\u5e02\u573a\uff0c\u60e0\u53ca\u66f4\u591a\u7684\u4e2d\u56fd\u60a3\u8005\uff0c\u4f8b\u5982\u7528\u4e8e\u6cbb\u7597\u8f6c\u7532\u72b6\u817a\u7d20\u86cb\u767d\u6dc0\u7c89\u6837\u53d8\u6027\u591a\u53d1\u6027\u795e\u7ecf\u75c5\uff08ATTR-PN\uff09\u7684\u7ef4\u8fbe\u5168<sup>&reg;<\/sup>\u5728\u4e2d\u56fd\u83b7\u6279\uff0c\u4e3a\u8be5\u7c7b\u7f55\u89c1\u75c5\u60a3\u8005\u5e26\u6765\u6709\u6548\u6cbb\u7597\u65b9\u6848\uff1b\u6cbb\u7597\u6210\u4eba\u91ce\u751f\u578b\u6216\u9057\u4f20\u578b\u8f6c\u7532\u72b6\u817a\u7d20\u86cb\u767d\u6dc0\u7c89\u6837\u53d8\u6027\u5fc3\u808c\u75c5\uff08ATTR-CM\uff09\u7684\u7ef4\u4e07\u5fc3<sup>&reg;<\/sup>\u4e3e\u884c\u4e86\u4e2d\u56fd\u9996\u53d1\uff0c\u586b\u8865\u6b64\u524d\u4e2d\u56fd\u5728ATTR-CM\u6cbb\u7597\u9886\u57df\u65e0\u6709\u6548\u6cbb\u7597\u836f\u7269\u7684\u7a7a\u767d\uff1b\u9002\u7528\u4e8e2\u5c81\u53ca\u4ee5\u4e0a\u8f7b\u5ea6\u81f3\u4e2d\u5ea6\u7279\u5e94\u6027\u76ae\u708e\u60a3\u8005\u7684\u5c40\u90e8\u5916\u7528\u6cbb\u7597\u7684\u975e\u6fc0\u7d20\u7c7b\u521b\u65b0\u5c0f\u5206\u5b50\u5916\u7528\u5904\u65b9\u836f\u8212\u5766\u660e&reg;\u4e5f\u5728\u56fd\u5185\u6b63\u5f0f\u4e0a\u5e02\u4e86\uff0c\u5f00\u542f\u4e86\u7279\u5e94\u6027\u76ae\u708e\u6cbb\u7597\u7684\u65b0\u7bc7\u7ae0\u3002\u57fa\u4e8e\u6b64\uff0c\u8f89\u745e\u5728\u4f17\u591a\u836f\u68b0\u5382\u5546\u4e2d\u8131\u9896\u800c\u51fa\uff0c\u8363\u83b7\u4e86\u4e50\u57ce\u5148\u884c\u533a\u7ba1\u7406\u5c40\u9881\u53d1\u7684\u201c\u6700\u4f73\u5408\u4f5c\u4f19\u4f34\u5956\u201d\u3002<\/p>\n<p>\u5728\u672c\u5c4a\u836f\u68b0\u5c55\u4e0a\uff0c\u8f89\u745e\u5c55\u793a\u4e86\u591a\u79cd\u521b\u65b0\u4ea7\u54c1\u53ca\u6cbb\u7597\u65b9\u6848\uff0c\u5305\u62ec\uff1a<\/p>\n<p><b>\u80bf\u7624\u9886\u57df<\/b><\/p>\n<ul type=\"disc\">\n<li>\u7528\u4e8eALK\u9633\u6027\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684Lorlatinib <\/li>\n<li>\u6cbb\u7597BRCA\u7a81\u53d8HER2\u9634\u6027\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u60a3\u8005\u7684Talazoparib <\/li>\n<li>\u7528\u4e8eBCG-na&iuml;ve NMIBC(\u975e\u808c\u5c42\u6d78\u6da6\u6027\u8180\u80f1\u764c)\u7684Sasanlimab <\/li>\n<li>\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6210\u4eba\u524d\u4f53B\u7ec6\u80de\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u7684Inotuzumab Ozogamicin <\/li>\n<li>\u4e0e\u4f4e\u5242\u91cf\u963f\u7cd6\u80de\u82f7\uff08LDAC\uff09\u8054\u7528\uff0c\u6cbb\u7597\u65b0\u8bca\u65ad\u7684\u5e74\u9f84\u226575\u5c81\u6216\u7531\u4e8e\u5408\u5e76\u75c7\u800c\u65e0\u6cd5\u4f7f\u7528\u9ad8\u5f3a\u5ea6\u8bf1\u5bfc\u5316\u7597\u7684\u6210\u4eba\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08AML\uff09\u60a3\u8005\u7684Glasdegib <\/li>\n<li>\u7528\u4e8e\u6cbb\u7597\u65b0\u8bca\u65ad\u7684CD33\u9633\u6027\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08\u5e74\u9f84\u22651\u4e2a\u6708\u7684\u513f\u7ae5\u548c\u6210\u4eba\uff09\uff0c\u4ee5\u53ca\u590d\u53d1\/\u96be\u6cbb\u6027CD33\u9633\u6027\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08\u5e74\u9f84\u5927\u4e8e\u7b49\u4e8e2\u5c81\u7684\u513f\u7ae5\u548c\u6210\u4eba\uff09\u7684Gemtuzumab Ozogamicin<\/li>\n<\/ul>\n<p><b>\u75ab\u82d7\u9886\u57df<\/b><\/p>\n<ul type=\"disc\">\n<li>\u7528\u4e8e\u5168\u5e74\u9f84\u4eba\u7fa4\u9884\u963213\u79cd\u7279\u5b9a\u8840\u6e05\u578b\u80ba\u708e\u7403\u83cc\u6027\u75be\u75c5\u768413\u4ef7\u80ba\u708e\u7403\u83cc\u591a\u7cd6\u7ed3\u5408\u75ab\u82d7\uff08\u5168\u4eba\u7fa4\uff09 <\/li>\n<li>\u7528\u4e8e10-25\u5c81\u4eba\u7fa4\u9884\u9632\u8111\u819c\u708e\u5948\u745f\u7403\u83cc\u8840\u6e05\u7fa4B\u5f15\u8d77\u7684\u4fb5\u88ad\u6027\u8111\u819c\u708e\u7403\u83cc\u75c5\u7684B\u65cf\u8111\u819c\u708e\u7403\u83cc\u75ab\u82d7 <\/li>\n<li>\u7528\u4e8e6\u5468\u9f84\u4ee5\u4e0a\u4eba\u7fa4\u9884\u9632ACWY\u7fa4\u8111\u819c\u708e\u7403\u83cc\u5f15\u8d77\u7684\u6d41\u884c\u6027\u8111\u810a\u9ad3\u819c\u708e\u76844\u4ef7\u8111\u819c\u708e\u591a\u7cd6\u7ed3\u5408\u75ab\u82d7 <\/li>\n<li>\u7528\u4e8e50\u5c81\u4ee5\u4e0a\u6210\u5e74\u4eba\u768420\u4ef7\u80ba\u708e\u7403\u83cc\u591a\u7cd6\u7ed3\u5408\u75ab\u82d7\uff08\u6210\u4eba\u9002\u5e94\u75c7\uff09 <\/li>\n<li>\u7528\u4e8e6\u5468\u9f84\u52305\u5c81\u768420\u4ef7\u80ba\u708e\u7403\u83cc\u591a\u7cd6\u7ed3\u5408\u75ab\u82d7\uff08\u513f\u7ae5\u9002\u5e94\u75c7\uff09 <\/li>\n<li>\u7528\u4e8e10-25\u5c81\u4eba\u7fa4\u9884\u9632ABCWY\u7fa4\u8111\u819c\u708e\u7403\u83cc\u5f15\u8d77\u7684\u6d41\u884c\u6027\u8111\u810a\u9ad3\u819c\u708e\u76845\u4ef7\u8111\u819c\u708e\u591a\u7cd6\u7ed3\u5408\u75ab\u82d7<\/li>\n<\/ul>\n<p><b>\u6297\u611f\u67d3\u9886\u57df<\/b><\/p>\n<ul type=\"disc\">\n<li>\u7528\u4e8e\u6210\u4eba\u53ca\u513f\u7ae5\u793e\u533a\u83b7\u5f97\u6027\u80ba\u708e(CAP)\uff0c\u4ee5\u53ca\u6210\u4eba\u53ca\u513f\u7ae5\u590d\u6742\u76ae\u80a4\u8f6f\u7ec4\u7ec7\u611f\u67d3\u7684Ceftaroline\uff08\u5934\u5b62\u7f57\u81a6\uff09 <\/li>\n<li>\u6cbb\u7597\u6210\u4eba\u4fb5\u88ad\u6027\u66f2\u9709\u75c5\u548c\u4fb5\u88ad\u6027\u6bdb\u9709\u75c5\u7684Cresemba\uff08\u827e\u6c99\u5eb7\u5511\uff09<\/li>\n<\/ul>\n<p><b>\u708e\u75c7<\/b><b>\u4e0e\u514d\u75ab<\/b><b>\u9886\u57df<\/b><\/p>\n<p>\u9002\u7528\u4e8e\u5bf9\u5916\u7528\u6cbb\u7597\u53cd\u5e94\u4e0d\u4f73\u6216\u4e0d\u9002\u5408\u8fd9\u4e9b\u6cbb\u7597\u768412\u5c81\u53ca\u4ee5\u4e0a\u4e2d\u81f3\u91cd\u5ea6\u7279\u5e94\u6027\u76ae\u708e\u60a3\u8005\u7684\u6cbb\u7597\uff0c\u5305\u62ec\u7f13\u89e3\u7619\u75d2\u7684Abrocitinib<\/p>\n<p>\u9002\u7528\u4e8e\u5927\u4e8e\u7b49\u4e8e12\u5c81\u6591\u79c3\u60a3\u8005\uff08\u5305\u62ec\u5168\u79c3\u548c\u666e\u79c3\uff09\u6cbb\u7597\u7684Ritlecitinib<\/p>\n<p>\u9002\u7528\u4e8e2\u5c81\u53ca\u4ee5\u4e0a\u8f7b\u5ea6\u81f3\u4e2d\u5ea6\u7279\u5e94\u6027\u76ae\u708e\u60a3\u8005\u7684\u5c40\u90e8\u5916\u7528\u6cbb\u7597\u7684\u514b\u7acb\u787c\u7f57\u8f6f\u818f<\/p>\n<p><b>\u7f55\u89c1\u75c5\u9886\u57df<\/b><\/p>\n<ul type=\"disc\">\n<li>\u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684PF-06939926 <\/li>\n<li>\u7528\u4e8e\u9002\u5e94\u75c7\u4e3a\u8840\u53cb\u75c5A\u548cB\u7684Marstacimab <\/li>\n<li>\u7528\u4e8e\u9002\u5e94\u75c7\u4e3a\u8840\u53cb\u75c5A\u7684Giroctocogene Fitelparvovec <\/li>\n<li>\u7528\u4e8e\u9002\u5e94\u75c7\u4e3a\u8840\u53cb\u75c5B\u7684Fidanacogene elaparvovec <\/li>\n<li>\u6cbb\u7597\u513f\u7ae5\u8f6f\u9aa8\u53d1\u80b2\u4e0d\u5168\u7684PF-07256472 <\/li>\n<li>\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u8f6c\u7532\u72b6\u817a\u7d20\u86cb\u767d\u6dc0\u7c89\u6837\u53d8\u6027\u591a\u53d1\u6027\u795e\u7ecf\u75c5I\u671f\u75c7\u72b6\u60a3\u8005\uff0c\u5ef6\u7f13\u5468\u56f4\u795e\u7ecf\u529f\u80fd\u635f\u5bb3\u7684\u6c2f\u82ef\u5511\u9178\u8461\u80fa\u8f6f\u80f6\u56ca <\/li>\n<li>\u9002\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u91ce\u751f\u578b\u6216\u9057\u4f20\u578b\u8f6c\u7532\u72b6\u817a\u7d20\u86cb\u767d\u6dc0\u7c89\u6837\u53d8\u6027\u5fc3\u808c\u75c5\uff08ATTR-CM\uff09\uff0c\u4ee5\u51cf\u5c11\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u53ca\u5fc3\u8840\u7ba1\u76f8\u5173\u4f4f\u9662\u7684\u6c2f\u82ef\u5511\u9178\u8f6f\u80f6\u56ca<\/li>\n<\/ul>\n<p><b>\u5185\u79d1\u9886\u57df<\/b><\/p>\n<ul type=\"disc\">\n<li>\u6cbb\u7597\u6210\u4eba\u4e2d\u91cd\u5ea6\u9aa8\u5173\u8282\u708e\u75bc\u75db\uff0c\u7f13\u89e3\u764c\u75db\u7684Tanezumab <\/li>\n<li>\u7528\u4e8e2\u578b\u7cd6\u5c3f\u75c5\u3001\u80a5\u80d6\u7684Danuglipron <\/li>\n<li>\u7528\u4e8e\u9ad8\u7518\u6cb9\u4e09\u916f\u8840\u75c7\u3001\u964d\u4f4e\u52a8\u8109\u7ca5\u6837\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75be\u75c5\u60a3\u8005\u7684\u5fc3\u8840\u7ba1\u4e8b\u4ef6\u98ce\u9669\u7684Vupanorsen<\/li>\n<\/ul>\n<p><i>\u63d0\u53ca\u7b2c\u4e8c\u6b21\u53c2\u5c55\uff0c\u8f89\u745e\u751f\u7269\u5236\u836f\u96c6\u56e2\u4e2d\u56fd\u533a\u5e02\u573a\u8425\u9500\u526f\u603b\u88c1\u738b\u6021\u4eb2\u8868\u793a\uff1a<\/i><i>\u201c<\/i><i>\u4f5c\u4e3a\u4e00\u4e2a\u5f00\u653e\u3001\u521b\u65b0\u3001\u5408\u4f5c\u7684\u5e73\u53f0\uff0c\u535a\u9ccc\u4e50\u57ce<\/i><i>\u2018<\/i><i>\u6c38\u4e0d\u843d\u5e55<\/i><i>\u2019<\/i><i>\u836f\u68b0\u5c55\u5df2\u6210\u4e3a\u63a8\u52a8\u4e2d\u56fd\u533b\u7597\u6c34\u5e73\u63d0\u5347\u548c\u521b\u65b0\u7597\u6cd5\u53ef\u53ca\u7684\u52a0\u901f\u5668\uff0c\u6ee1\u8db3\u4e2d\u56fd\u5e7f\u5927\u60a3\u8005\u6025\u8feb\u7684\u4e34\u5e8a\u6cbb\u7597\u9700\u6c42\u3002\u540c\u65f6\uff0c\u4e5f\u4e3a\u6211\u4eec\u521b\u9020\u4e86\u5f00\u5c55\u5e7f\u6cdb\u5408\u4f5c\u3001\u63a2\u7d22\u521b\u65b0\u4e1a\u52a1\u53d1\u5c55\u6a21\u5f0f\u7684\u5b9d\u8d35\u673a\u4f1a\u3002\u6211\u4eec\u975e\u5e38\u9ad8\u5174\u80fd\u518d\u6b21\u501f\u52a9\u535a\u9ccc\u836f\u68b0\u5c55\u8fd9\u4e2a\u5e73\u53f0\uff0c\u5c55\u793a\u8f89\u745e\u7684\u7a81\u7834\u521b\u65b0\uff0c\u5e76\u901a\u8fc7<\/i><i>\u2018<\/i><i>\u5148\u884c\u5148\u8bd5<\/i><i>\u2019<\/i><i>\u653f\u7b56\uff0c\u66f4\u5feb\u83b7\u5f97\u771f\u5b9e\u4e16\u754c\u4e34\u5e8a\u8bc1\u636e\uff0c\u63a8\u52a8\u4ea7\u54c1\u65e9\u65e5\u5728\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\u3002<\/i><i>\u201d<\/i><\/p>\n<p><b>\u84c4\u529b\u4e2d\u56fd\u521b\u65b0\u4e0e\u5168\u7403\u540c\u6b65<\/b><\/p>\n<p>\u8fdb\u5165\u4e2d\u56fd\u5e02\u573a30\u4f59\u5e74\u6765\uff0c\u8f89\u745e\u59cb\u7ec8\u81f4\u529b\u4e8e\u201c\u6210\u4e3a\u4e2d\u56fd\u533b\u7597\u536b\u751f\u4f53\u7cfb\u91cd\u8981\u7ec4\u6210\u90e8\u5206\u201d\uff0c\u5f15\u8fdb\u4e8660\u591a\u4e2a\u521b\u65b0\u836f\u7269\uff0c\u6d89\u53ca\u80bf\u7624\u3001\u75ab\u82d7\u3001\u6297\u611f\u67d3\u3001\u708e\u75c7\u4e0e\u514d\u75ab\u3001\u7f55\u89c1\u75c5\u7b49\u4e94\u5927\u9886\u57df\uff0c\u5e76\u57282019\u5e74\u63d0\u51fa\u4e86\u52a9\u529b\u4e2d\u56fd\u672c\u571f\u7684\u4e34\u5e8a\u7814\u7a76\u8d70\u5411\u5168\u7403\u7684\u91cf\u5316\u76ee\u6807\uff1a\u201c80%&amp;80%\u201d\uff0c\u5373\u52302022\u5e74\uff0c\u5b9e\u73b0\u4e2d\u56fd\u53c2\u52a080%\u7684\u5168\u7403\u65e9\u671f\u4ee5\u53ca\u5173\u952e\u4e09\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5176\u4e2d80%\u7684\u9879\u76ee\u505a\u5230\u540c\u671f\u7533\u62a5\u3002<\/p>\n<p><i>\u8f89\u745e\uff08\u4e2d\u56fd\uff09\u7814\u7a76\u5f00\u53d1\u6709\u9650\u516c\u53f8\u603b\u7ecf\u7406\u9648\u671d\u534e\u8868\u793a\uff1a<\/i><i>\u201c<\/i><i>\u79d1\u5b66\u4e0d\u5206\u56fd\u754c\uff0c\u8f89\u745e\u59cb\u7ec8\u81f4\u529b\u4e8e\u79d1\u5b66\u7814\u7a76\uff0c\u6211\u4eec\u575a\u6301\u6295\u5165\u5e76\u4e0d\u65ad\u4f18\u5316\u8d44\u6e90\uff0c\u65e0\u8bba\u662f\u4e2d\u56fd\u60a3\u8005\u8fd8\u662f\u5168\u7403\u60a3\u8005\uff0c\u90fd\u80fd\u591f\u901a\u8fc7\u8f89\u745e\u7684\u79d1\u5b66\u4ea7\u51fa\u83b7\u76ca\u3002\u4e3a\u60a3\u8005\u5e26\u6765\u6539\u53d8\u5176\u751f\u6d3b\u7684\u7a81\u7834\u521b\u65b0\u4e00\u76f4\u90fd\u662f\u6211\u4eec\u7684\u76ee\u6807\u3002\u622a\u81f3<\/i><i>2021<\/i><i>\u5e74<\/i><i>2<\/i><i>\u6708\uff0c\u8f89\u745e\u5168\u7403\u5171\u6709<\/i><i>95<\/i><i>\u4e2a\u521b\u65b0\u836f\u7814\u53d1\u9879\u76ee\u6b63\u5728\u5feb\u901f\u63a8\u8fdb\u4e2d\u3002\u51ed\u501f\u6df1\u539a\u7684\u751f\u7269\u5236\u836f\u7814\u53d1\u5e95\u8574\uff0c\u4ee5\u53ca\u6df1\u8015\u4e2d\u56fd<\/i><i>30<\/i><i>\u4f59\u5e74\u7684\u7ecf\u9a8c\u79ef\u7d2f\uff0c\u8f89\u745e\u7cbe\u51c6\u6d1e\u5bdf\u4e2d\u56fd\u60a3\u8005\u7684\u9700\u6c42\uff0c\u6c47\u96c6\u5168\u7403\u8d44\u6e90\uff0c\u5e0c\u671b\u4e0e\u6211\u4eec\u7684\u836f\u653f\u7ba1\u7406\u90e8\u95e8\u53ca\u4e34\u5e8a\u7814\u7a76\u4e13\u5bb6\u4eec\u7ee7\u7eed\u901a\u529b\u5408\u4f5c\uff0c\u5c06\u5168\u7403\u540c\u671f\u7814\u53d1\u7684<\/i><i>first-in-class<\/i><i>\u3001<\/i><i>best-in-class<\/i><i>\u4ea7\u54c1\u5feb\u901f\u5f15\u5165\u4e2d\u56fd\uff0c\u5728<\/i><i>2022<\/i><i>\u5e74\u5b9e\u73b0<\/i><i>\u201880%&amp;80%\u2019<\/i><i>\u7684\u76ee\u6807\uff0c\u8ba9\u4e2d\u56fd\u60a3\u8005\u5c3d\u65e9\u83b7\u5f97\u5168\u7403\u7684\u7a81\u7834\u521b\u65b0\u6cbb\u7597\uff0c\u4e3a\u5b9e\u73b0\u5065\u5eb7\u4e2d\u56fd<\/i><i>2030<\/i><i>\u6218\u7565\u76ee\u6807\u4f5c\u51fa\u6211\u4eec\u7684\u8d21\u732e\u3002<\/i><i>\u201d<\/i><\/p>\n<p>\u6076\u6027\u80bf\u7624\u5df2\u7ecf\u6210\u4e3a\u4e25\u91cd\u5a01\u80c1\u4e2d\u56fd\u4eba\u7fa4\u5065\u5eb7\u7684\u4e3b\u8981\u516c\u5171\u536b\u751f\u95ee\u9898\u4e4b\u4e00\u3002\u6839\u636e\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u56fd\u9645\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3\u53d1\u5e03\u76842020\u5e74\u5168\u7403\u6700\u65b0\u764c\u75c7\u8d1f\u62c5\u6570\u636e\uff0c2020\u5e74\u5168\u7403\u65b0\u53d1\u764c\u75c7\u75c5\u4f8b1929\u4e07\u4f8b\uff0c\u5176\u4e2d\u4e2d\u56fd\u65b0\u53d1\u764c\u75c7\u75c5\u4f8b\u4e3a457\u4e07\u4f8b\uff0c\u5360\u5168\u740323.7%\uff0c\u5c45\u5168\u7403\u7b2c\u4e00\u3002\u76ee\u524d\uff0c\u8f89\u745e\u7684\u6297\u80bf\u7624\u521b\u65b0\u836f\u4e2d\u670911\u4e2a\u4ea7\u54c1\u8fdb\u5165\u4e2d\u56fd\uff0c\u5206\u522b\u6d89\u53ca\u80ba\u764c\u3001\u4e73\u817a\u764c\u7b49\u75be\u75c5\u9886\u57df\u3002\u8f89\u745e\u5e0c\u671b\u672a\u6765\u80fd\u6709\u66f4\u591a\u7684\u521b\u65b0\u6297\u80bf\u7624\u4ea7\u54c1\u5728\u4e2d\u56fd\u4e0a\u5e02\uff0c\u52a9\u529b\u5065\u5eb7\u4e2d\u56fd\u3002<\/p>\n<p>\u8f89\u745e\u4e00\u76f4\u5728\u63a8\u8fdb\u7528\u75ab\u82d7\u6cbb\u7597\u4e00\u7cfb\u5217\u4e25\u91cd\u7684\u3001\u751a\u81f3\u5371\u53ca\u751f\u547d\u7684\u75be\u75c5\uff0c\u5305\u62ec\u5a74\u5e7c\u513f\u548c\u8001\u5e74\u4eba\u6700\u4e3a\u4e25\u91cd\u7684\u7ec6\u83cc\u611f\u67d3\u3002\u4ece2017\u5e74\u83b7\u6279\u5728\u534e\u4e0a\u5e02&nbsp;\uff0c\u8f89\u745e\u6c9b\u513f13&reg;\u5e2e\u52a9\u4e2d\u56fd6\u5468\u9f84\u81f315\u6708\u9f84\u5a74\u5e7c\u513f\u9884\u9632\u753113\u79cd\u80ba\u708e\u7403\u83cc\u8840\u6e05\u578b\u5bfc\u81f4\u7684\u76f8\u5173\u4fb5\u88ad\u6027\u75be\u75c5\u3002\u6b64\u6b21\u5c55\u793a\u768420\u4ef7\u80ba\u708e\u7403\u83cc\u591a\u7cd6\u7ed3\u5408\u75ab\u82d7\uff0c\u9884\u9632\u753120\u79cd\u80ba\u708e\u94fe\u7403\u83cc\u8840\u6e05\u578b\u5f15\u8d77\u7684\u4fb5\u88ad\u6027\u548c\u975e\u4fb5\u88ad\u6027\u75be\u75c5\uff0c\u73b0\u5df2\u83b7\u5f97\u7f8e\u56fdFDA\u4f18\u5148\u5ba1\u67e5\u3002<\/p>\n<p>\u7ec6\u83cc\u6297\u751f\u7d20\u8010\u836f\u6027\u7684\u589e\u52a0\u548c\u65b0\u6297\u751f\u7d20\u7684\u7f3a\u4e4f\u662f\u5f53\u524d\u5168\u7403\u4e3b\u8981\u7684\u7ec6\u83cc\u611f\u67d3\u76f8\u5173\u5065\u5eb7\u95ee\u9898\u3002\u5728\u4e2d\u56fd\uff0c\u8f89\u745e\u79ef\u6781\u4e0e\u6709\u5173\u653f\u5e9c\u90e8\u95e8\u3001\u79d1\u7814\/\u533b\u7597\u673a\u6784\u3001\u5b66\u672f\u7ec4\u7ec7\u7b49\u5404\u65b9\u9762\u5bc6\u5207\u5408\u4f5c\uff0c\u5728\u5408\u7406\u7528\u836f\u3001\u57fa\u5c42\u5b66\u79d1\u5efa\u8bbe\u3001\u8bca\u7597\u4e00\u4f53\u5316\u7b49\u65b9\u9762\u4e0d\u65ad\u8fdb\u884c\u63a2\u7d22\uff0c\u4ee5\u4fc3\u8fdb\u6297\u83cc\u836f\u7269\u5408\u7406\u5e94\u7528\u3001\u904f\u5236\u7ec6\u83cc\u8010\u836f\u8d8b\u52bf\u3002\u540c\u65f6\uff0c\u901a\u8fc7\u4e30\u5bcc\u7684\u4ea7\u54c1\u7ec4\u5408\uff0c\u5305\u62ec\u5df2\u4e0a\u5e02\u4ea7\u54c1\u548c\u672a\u6765\u6709\u671b\u4e0a\u5e02\u7684\u827e\u6c99\u5eb7\u5511\u3001\u5934\u5b62\u7f57\u81a6\uff0c\u4e3a\u4e2d\u56fd\u60a3\u8005\u6297\u611f\u67d3\u6cbb\u7597\u63d0\u4f9b\u6709\u529b\u4fdd\u969c\u3002<\/p>\n<p>\u5728\u708e\u75c7\u4e0e\u514d\u75ab\u9886\u57df\uff0c\u4e2d\u56fd\u7684\u7279\u5e94\u6027\u76ae\u708e\u53d1\u75c5\u7387\u5448\u9010\u5e74\u589e\u957f\u8d8b\u52bf\uff0c\u5c24\u5176\u662f\u4e2d\u91cd\u5ea6\u7279\u5e94\u6027\u76ae\u708e\u60a3\u8005\uff0c\u4e34\u5e8a\u4e9f\u9700\u5b89\u5168\u3001\u6709\u6548\u6cbb\u7597\u624b\u6bb5\u3002\u53bb\u5e74\u5df2\u5728\u56fd\u5185\u4e0a\u5e02\u7684\u8212\u5766\u660e<sup>&reg;<\/sup> \uff0c\u662f\u4e00\u4e2a\u65b0\u578b\u7684\u975e\u753e\u4f53\u7c7b\u78f7\u9178\u4e8c\u916f\u91764 (PDE-4)\u6291\u5236\u5242\uff0c\u7528\u4e8e2\u5c81\u53ca\u4ee5\u4e0a\u8f7b\u5ea6\u81f3\u4e2d\u5ea6\u7279\u5e94\u6027\u76ae\u708e\u60a3\u8005\u7684\u5c40\u90e8\u6cbb\u7597\u3002\u4eca\u5e74\u5c55\u793a\u7684Abrocitinib\uff0c\u9002\u7528\u4e8e\u5bf9\u5916\u7528\u6cbb\u7597\u53cd\u5e94\u4e0d\u4f73\u6216\u4e0d\u9002\u5408\u8fd9\u4e9b\u6cbb\u7597\u7684&nbsp;12 \u5c81\u53ca\u4ee5\u4e0a\u4e2d\u81f3\u91cd\u5ea6\u7279\u5e94\u6027\u76ae\u708e\u60a3\u8005\u7684\u6cbb\u7597\uff0c\u5305\u62ec\u7f13\u89e3\u7619\u75d2\u3002\u672c\u54c1\u5728\u4e2d\u56fd\u3001\u7f8e\u56fd\uff0c\u6b27\u76df\u548c\u65e5\u672c\u5b9e\u73b0\u4e86\u540c\u6b65\u7533\u62a5\uff0c\u4e14\u5728\u4e2d\u56fd\u548c\u7f8e\u56fd\u5747\u88ab\u6388\u4e88\u4f18\u5148\u5ba1\u8bc4\u8d44\u683c\u3002<\/p>\n<p>\u7f55\u89c1\u75c5\u9886\u57df\u662f\u8f89\u745e\u957f\u671f\u5173\u6ce8\u5e76\u4e0d\u65ad\u6295\u5165\u7684\u9886\u57df\uff0c\u76ee\u524d\u5728\u56fd\u5185\u9488\u5bf9\u4e24\u5927\u7f55\u89c1\u75c5\u9886\u57df\uff0cATTR\u4ee5\u53ca\u8840\u53cb\u75c5\uff0c\u5df2\u7ecf\u4e0a\u5e02\u4e864\u6b3e\u836f\u7269\u3002\u5728\u8f89\u745e\u5168\u7403\u5728\u7814\u4ea7\u54c1\u4e2d\uff0c\u670930\u4f59\u4e2a\u4ea7\u54c1\u5f52\u5c5e\u7f55\u89c1\u75c5\uff0c\u6db5\u76d6\u8840\u6db2\u75c5\u3001\u795e\u7ecf\u808c\u8089\u3001\u5fc3\u8840\u7ba1\u7b49\u9886\u57df\u3002\u672a\u6765\u51e0\u5e74\uff0c\u8f89\u745e\u8ba1\u5212\u9646\u7eed\u5c06\u4e0d\u540c\u7684\u521b\u65b0\u6cbb\u7597\u548c\u4ea7\u54c1\u5f15\u5165\u4e2d\u56fd\uff0c\u5305\u62ec\u5728\u6b64\u6b21\u5c55\u793a\u7684\u6cbb\u7597\u675c\u6c0f\u8fdb\u884c\u578b\u808c\u8425\u517b\u4e0d\u826f\u7684PF-06939926\u4ee5\u53ca\u7528\u4e8e\u9002\u5e94\u75c7\u4e3a\u8840\u53cb\u75c5A\u548cB\u7684Marstacimab\u7b49\u3002<\/p>\n<p>OA\uff08\u9aa8\u5173\u8282\u708e\uff09\u662f\u6700\u5e38\u89c1\u7684\u5173\u8282\u708e\u7c7b\u578b\uff0c\u5728\u4e2d\u56fd\u62e5\u6709\u6781\u9ad8\u53d1\u75c5\u7387\u3002\u5f53\u524d\uff0cOA\u60a3\u8005\u4ecd\u65e7\u666e\u904d\u4f7f\u7528\u963f\u7247\u7c7b\u836f\u7269\u8fdb\u884c\u9547\u75db\uff0c\u4f46\u7531\u4e8e\u8fd1\u5e74\u6765\u963f\u7247\u7c7b\u836f\u7269\u7684\u6ee5\u7528\u5371\u673a\uff0c\u60a3\u8005\u4eec\u6025\u9700\u4e00\u6b3e\u5b89\u5168\u7684\u65b0\u578b\u7597\u6cd5\u5e2e\u52a9\u4ed6\u4eec\u51cf\u8f7bOA\u5e26\u6765\u7684\u75bc\u75db\u3002\u8f89\u745e\u6b64\u6b21\u5728\u836f\u68b0\u5c55\u5c55\u793a\u7684\u5185\u79d1\u836f\u7269\u4e2d\uff0cTanezumab\u662f\u4e00\u79cd\u975e\u963f\u7247\u7c7b\u6b62\u75db\u836f\uff0c\u5f52\u7c7b\u4e3a\u795e\u7ecf\u751f\u957f\u56e0\u5b50\uff08NGF\uff09\u6291\u5236\u5242\u3002\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u663e\u793a\uff0c\u901a\u8fc7\u9009\u62e9\u6027\u6291\u5236NGF\uff0cTanezumab\u53ef\u4ee5\u6709\u52a9\u4e8e\u963b\u6b62\u808c\u8089\u3001\u76ae\u80a4\u6216\u5668\u5b98\u4ea7\u751f\u7684\u75bc\u75db\u4fe1\u53f7\u5230\u8fbe\u810a\u9ad3\u548c\u5927\u8111\uff0c\u4ece\u800c\u5b89\u5168\u51cf\u8f7b\u75bc\u75db\u3002<\/p>\n<p>\u8f89\u745e\u59cb\u7ec8\u81f4\u529b\u4e8e\u201c\u6210\u4e3a\u4e2d\u56fd\u533b\u7597\u536b\u751f\u4f53\u7cfb\u7684\u91cd\u8981\u7ec4\u6210\u90e8\u5206\u201d\uff0c\u627f\u8bfa\u5e76\u79ef\u6781\u53c2\u4e0e\u4fc3\u8fdb\u4e2d\u56fd\u533b\u7597\u536b\u751f\u4e8b\u4e1a\u7684\u53d1\u5c55\u548c\u63d0\u9ad8\u4eba\u6c11\u5065\u5eb7\u6c34\u5e73\u3002\u6211\u4eec\u5fd7\u5728\u901a\u8fc7\u521b\u65b0\u7684\u3001\u5bcc\u6709\u793e\u4f1a\u8d23\u4efb\u5e76\u4e14\u5546\u4e1a\u53ef\u884c\u7684\u65b9\u5f0f\uff0c\u6ee1\u8db3\u4e2d\u56fd14\u4ebf\u4eba\u6c11\u591a\u6837\u5316\u7684\u533b\u7597\u670d\u52a1\u9700\u6c42\u3002<\/p>\n<p><b>\u6ce8\uff1a\u672c\u65b0\u95fb\u7a3f\u4ec5\u4e3a\u533b\u5b66\u4e13\u4e1a\u4fe1\u606f\u5206\u4eab\uff0c\u6587\u4e2d\u6240\u63d0\u53ca\u4ea7\u54c1\u591a\u6570\u4e3a\u56fd\u5185\u672a\u83b7\u6279\u4e0a\u5e02\u4ea7\u54c1\uff0c\u90e8\u5206\u4e3a\u5168\u7403\u8303\u56f4\u5185\u5728\u7814\u4ea7\u54c1\u3002<\/b><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8212; \u7b2c\u4e8c\u671f\u5065\u5eb7\u6d77\u5357-\u4e50\u57ce\u884c\u66a8\u201c\u6c38\u4e0d\u843d\u5e55\u201d\u56fd\u9645\u836f\u68b0\u5c55\u6b63\u5f0f\u5f00\u5e55 &#8212; \u521b\u65b0\u52a9\u529b\u5065\u5eb7\u4e2d\u56fd\uff0c\u8f89\u745e\u8363\u83b7\u201c\u6700\u4f73\u5408\u4f5c\u4f19\u4f34\u5956\u201d \u6d77\u5357\u535a\u9ccc2021\u5e744\u670813\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 4\u670813\u65e5\uff0c\u7531\u6d77\u5357\u7701\u535a\u9ccc\u4e50\u57ce\u56fd\u9645\u533b\u7597\u65c5\u6e38\u5148\u884c\u533a\uff08\u4ee5\u4e0b\u7b80\u79f0\u4e50\u57ce\u5148\u884c\u533a\uff09\u7ba1\u7406\u5c40\u4e3b\u529e\u7684\u7b2c\u4e8c\u671f\u5065\u5eb7\u6d77\u5357-\u4e50\u57ce\u884c\u66a8\u201c\u6c38\u4e0d\u843d\u5e55\u201d\u56fd\u9645\u836f\u68b0\u5c55\u5728\u535a\u9ccc\u5982\u671f\u4e3e\u884c\u3002\u4f5c\u4e3a\u53c2\u4e0e\u7b2c\u4e00\u671f\u836f\u68b0\u5c55\u7684\u91cd\u70b9\u5382\u5546\uff0c\u8f89\u745e\u4e0d\u4ec5\u518d\u5ea6\u643a\u4e94\u5927\u9886\u57df\u591a\u79cd\u6cbb\u7597\u65b9\u6848\u4eae\u76f8\uff0c\u5411\u4e0e\u4f1a\u8005\u5c55\u793a\u4e86\u8f89\u745e\u5df2\u4e0a\u5e02\u53ca\u5728\u7814\u7684\u521b\u65b0\u4ea7\u54c1\uff0c\u540c\u65f6\u8363\u83b7\u4e86\u4e50\u57ce\u5148\u884c\u533a\u7ba1\u7406\u5c40\u9881\u53d1\u7684\u201c\u6700\u4f73\u5408\u4f5c\u4f19\u4f34\u5956\u201d\u3002 \u8d21\u732e\u521b\u65b0\u667a\u6167\uff0c\u505a\u5065\u5eb7\u4e2d\u56fd\u7684\u201c\u6700\u4f73\u5408\u4f5c\u4f19\u4f34\u201d \u201c\u6c38\u4e0d\u843d\u5e55\u201d\u56fd\u9645\u521b\u65b0\u836f\u68b0\u5c55\uff0c\u65e2\u662f\u4e50\u57ce\u5148\u884c\u533a\u52a0\u5feb\u53d1\u5c55\u7684\u4e00\u4e2a\u7f29\u5f71\uff0c\u4e5f\u662f\u52a9\u529b\u8de8\u56fd\u836f\u4f01\u5c06\u672a\u5728\u56fd\u5185\u4e0a\u5e02\u7684\u521b\u65b0\u836f\u68b0\u52a0\u901f\u843d\u5730\u4e2d\u56fd\u7684\u91cd\u8981\u7a97\u53e3\u3002 \u4e50\u57ce\u5148\u884c\u533a\u7ba1\u7406\u5c40\u515a\u59d4\u4e66\u8bb0\u3001\u5c40\u957f\u987e\u521a\u8868\u793a\uff1a\u201c\u53bb\u5e74\uff0c\u5728\u7701\u59d4\u3001\u7701\u653f\u5e9c\u9886\u5bfc\u4e0e\u591a\u804c\u80fd\u90e8\u95e8\u7684\u5171\u540c\u52aa\u529b\u4e0b\uff0c\u5728\u4f17\u591a\u836f\u68b0\u4f01\u4e1a\u7684\u652f\u6301\u4e0b\uff0c\u7b2c\u4e00\u671f\u5c55\u4f1a\u83b7\u5f97\u4e86\u5706\u6ee1\u7684\u6210\u6548\uff0c\u4e5f\u8ba9\u5927\u5bb6\u770b\u5230\u4e86\u4e50\u57ce\u96c6\u6210\u521b\u65b0\u7684\u53d1\u5c55\u52bf\u5934\u3002\u4eca\u5e74\u7b2c\u4e8c\u671f\uff0c\u975e\u5e38\u9ad8\u5174\u770b\u5230\u5305\u62ec\u8f89\u745e\u5728\u5185\u7684\u5168\u7403\u5353\u8d8a\u836f\u4f01\u7ee7\u7eed\u4e3a\u4e2d\u56fd\u5927\u4f17\u5e26\u6765\u4e86\u521b\u65b0\u4ea7\u54c1\u53ca\u6cbb\u7597\u65b9\u6848\uff0c\u4e3a\u5065\u5eb7\u4e2d\u56fd\u8d21\u732e\u521b\u65b0\u667a\u6167\u3002\u4e0b\u4e00\u6b65\uff0c\u4e50\u57ce\u5148\u884c\u533a\u5c06\u6301\u7eed\u4e0d\u65ad\u4f18\u5316\u8425\u5546\u73af\u5883\uff0c\u8ba9\u66f4\u591a\u7684\u836f\u68b0\u5382\u5546\u548c\u56ed\u533a\u4f01\u4e1a\u80fd\u591f\u4eab\u53d7\u5230\u6d77\u5357\u81ea\u8d38\u6e2f\u7684\u7ea2\u5229\u3001\u4e50\u57ce\u7684\u7ea2\u5229\u3002\u201d&nbsp; \u51ed\u501f\u836f\u68b0\u5c55\u7684\u5927\u821e\u53f0\uff0c\u8f89\u745e\u53bb\u5e74\u5c55\u793a\u7684\u521b\u65b0\u836f\u5f97\u4ee5\u5feb\u901f\u5f15\u5165\u4e2d\u56fd\u5e02\u573a\uff0c\u60e0\u53ca\u66f4\u591a\u7684\u4e2d\u56fd\u60a3\u8005\uff0c\u4f8b\u5982\u7528\u4e8e\u6cbb\u7597\u8f6c\u7532\u72b6\u817a\u7d20\u86cb\u767d\u6dc0\u7c89\u6837\u53d8\u6027\u591a\u53d1\u6027\u795e\u7ecf\u75c5\uff08ATTR-PN\uff09\u7684\u7ef4\u8fbe\u5168&reg;\u5728\u4e2d\u56fd\u83b7\u6279\uff0c\u4e3a\u8be5\u7c7b\u7f55\u89c1\u75c5\u60a3\u8005\u5e26\u6765\u6709\u6548\u6cbb\u7597\u65b9\u6848\uff1b\u6cbb\u7597\u6210\u4eba\u91ce\u751f\u578b\u6216\u9057\u4f20\u578b\u8f6c\u7532\u72b6\u817a\u7d20\u86cb\u767d\u6dc0\u7c89\u6837\u53d8\u6027\u5fc3\u808c\u75c5\uff08ATTR-CM\uff09\u7684\u7ef4\u4e07\u5fc3&reg;\u4e3e\u884c\u4e86\u4e2d\u56fd\u9996\u53d1\uff0c\u586b\u8865\u6b64\u524d\u4e2d\u56fd\u5728ATTR-CM\u6cbb\u7597\u9886\u57df\u65e0\u6709\u6548\u6cbb\u7597\u836f\u7269\u7684\u7a7a\u767d\uff1b\u9002\u7528\u4e8e2\u5c81\u53ca\u4ee5\u4e0a\u8f7b\u5ea6\u81f3\u4e2d\u5ea6\u7279\u5e94\u6027\u76ae\u708e\u60a3\u8005\u7684\u5c40\u90e8\u5916\u7528\u6cbb\u7597\u7684\u975e\u6fc0\u7d20\u7c7b\u521b\u65b0\u5c0f\u5206\u5b50\u5916\u7528\u5904\u65b9\u836f\u8212\u5766\u660e&reg;\u4e5f\u5728\u56fd\u5185\u6b63\u5f0f\u4e0a\u5e02\u4e86\uff0c\u5f00\u542f\u4e86\u7279\u5e94\u6027\u76ae\u708e\u6cbb\u7597\u7684\u65b0\u7bc7\u7ae0\u3002\u57fa\u4e8e\u6b64\uff0c\u8f89\u745e\u5728\u4f17\u591a\u836f\u68b0\u5382\u5546\u4e2d\u8131\u9896\u800c\u51fa\uff0c\u8363\u83b7\u4e86\u4e50\u57ce\u5148\u884c\u533a\u7ba1\u7406\u5c40\u9881\u53d1\u7684\u201c\u6700\u4f73\u5408\u4f5c\u4f19\u4f34\u5956\u201d\u3002 \u5728\u672c\u5c4a\u836f\u68b0\u5c55\u4e0a\uff0c\u8f89\u745e\u5c55\u793a\u4e86\u591a\u79cd\u521b\u65b0\u4ea7\u54c1\u53ca\u6cbb\u7597\u65b9\u6848\uff0c\u5305\u62ec\uff1a \u80bf\u7624\u9886\u57df \u7528\u4e8eALK\u9633\u6027\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684Lorlatinib \u6cbb\u7597BRCA\u7a81\u53d8HER2\u9634\u6027\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u60a3\u8005\u7684Talazoparib \u7528\u4e8eBCG-na&iuml;ve NMIBC(\u975e\u808c\u5c42\u6d78\u6da6\u6027\u8180\u80f1\u764c)\u7684Sasanlimab \u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6210\u4eba\u524d\u4f53B\u7ec6\u80de\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u7684Inotuzumab Ozogamicin \u4e0e\u4f4e\u5242\u91cf\u963f\u7cd6\u80de\u82f7\uff08LDAC\uff09\u8054\u7528\uff0c\u6cbb\u7597\u65b0\u8bca\u65ad\u7684\u5e74\u9f84\u226575\u5c81\u6216\u7531\u4e8e\u5408\u5e76\u75c7\u800c\u65e0\u6cd5\u4f7f\u7528\u9ad8\u5f3a\u5ea6\u8bf1\u5bfc\u5316\u7597\u7684\u6210\u4eba\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08AML\uff09\u60a3\u8005\u7684Glasdegib \u7528\u4e8e\u6cbb\u7597\u65b0\u8bca\u65ad\u7684CD33\u9633\u6027\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08\u5e74\u9f84\u22651\u4e2a\u6708\u7684\u513f\u7ae5\u548c\u6210\u4eba\uff09\uff0c\u4ee5\u53ca\u590d\u53d1\/\u96be\u6cbb\u6027CD33\u9633\u6027\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08\u5e74\u9f84\u5927\u4e8e\u7b49\u4e8e2\u5c81\u7684\u513f\u7ae5\u548c\u6210\u4eba\uff09\u7684Gemtuzumab Ozogamicin \u75ab\u82d7\u9886\u57df \u7528\u4e8e\u5168\u5e74\u9f84\u4eba\u7fa4\u9884\u963213\u79cd\u7279\u5b9a\u8840\u6e05\u578b\u80ba\u708e\u7403\u83cc\u6027\u75be\u75c5\u768413\u4ef7\u80ba\u708e\u7403\u83cc\u591a\u7cd6\u7ed3\u5408\u75ab\u82d7\uff08\u5168\u4eba\u7fa4\uff09 \u7528\u4e8e10-25\u5c81\u4eba\u7fa4\u9884\u9632\u8111\u819c\u708e\u5948\u745f\u7403\u83cc\u8840\u6e05\u7fa4B\u5f15\u8d77\u7684\u4fb5\u88ad\u6027\u8111\u819c\u708e\u7403\u83cc\u75c5\u7684B\u65cf\u8111\u819c\u708e\u7403\u83cc\u75ab\u82d7 \u7528\u4e8e6\u5468\u9f84\u4ee5\u4e0a\u4eba\u7fa4\u9884\u9632ACWY\u7fa4\u8111\u819c\u708e\u7403\u83cc\u5f15\u8d77\u7684\u6d41\u884c\u6027\u8111\u810a\u9ad3\u819c\u708e\u76844\u4ef7\u8111\u819c\u708e\u591a\u7cd6\u7ed3\u5408\u75ab\u82d7 \u7528\u4e8e50\u5c81\u4ee5\u4e0a\u6210\u5e74\u4eba\u768420\u4ef7\u80ba\u708e\u7403\u83cc\u591a\u7cd6\u7ed3\u5408\u75ab\u82d7\uff08\u6210\u4eba\u9002\u5e94\u75c7\uff09 \u7528\u4e8e6\u5468\u9f84\u52305\u5c81\u768420\u4ef7\u80ba\u708e\u7403\u83cc\u591a\u7cd6\u7ed3\u5408\u75ab\u82d7\uff08\u513f\u7ae5\u9002\u5e94\u75c7\uff09 \u7528\u4e8e10-25\u5c81\u4eba\u7fa4\u9884\u9632ABCWY\u7fa4\u8111\u819c\u708e\u7403\u83cc\u5f15\u8d77\u7684\u6d41\u884c\u6027\u8111\u810a\u9ad3\u819c\u708e\u76845\u4ef7\u8111\u819c\u708e\u591a\u7cd6\u7ed3\u5408\u75ab\u82d7 \u6297\u611f\u67d3\u9886\u57df \u7528\u4e8e\u6210\u4eba\u53ca\u513f\u7ae5\u793e\u533a\u83b7\u5f97\u6027\u80ba\u708e(CAP)\uff0c\u4ee5\u53ca\u6210\u4eba\u53ca\u513f\u7ae5\u590d\u6742\u76ae\u80a4\u8f6f\u7ec4\u7ec7\u611f\u67d3\u7684Ceftaroline\uff08\u5934\u5b62\u7f57\u81a6\uff09 \u6cbb\u7597\u6210\u4eba\u4fb5\u88ad\u6027\u66f2\u9709\u75c5\u548c\u4fb5\u88ad\u6027\u6bdb\u9709\u75c5\u7684Cresemba\uff08\u827e\u6c99\u5eb7\u5511\uff09 \u708e\u75c7\u4e0e\u514d\u75ab\u9886\u57df \u9002\u7528\u4e8e\u5bf9\u5916\u7528\u6cbb\u7597\u53cd\u5e94\u4e0d\u4f73\u6216\u4e0d\u9002\u5408\u8fd9\u4e9b\u6cbb\u7597\u768412\u5c81\u53ca\u4ee5\u4e0a\u4e2d\u81f3\u91cd\u5ea6\u7279\u5e94\u6027\u76ae\u708e\u60a3\u8005\u7684\u6cbb\u7597\uff0c\u5305\u62ec\u7f13\u89e3\u7619\u75d2\u7684Abrocitinib \u9002\u7528\u4e8e\u5927\u4e8e\u7b49\u4e8e12\u5c81\u6591\u79c3\u60a3\u8005\uff08\u5305\u62ec\u5168\u79c3\u548c\u666e\u79c3\uff09\u6cbb\u7597\u7684Ritlecitinib \u9002\u7528\u4e8e2\u5c81\u53ca\u4ee5\u4e0a\u8f7b\u5ea6\u81f3\u4e2d\u5ea6\u7279\u5e94\u6027\u76ae\u708e\u60a3\u8005\u7684\u5c40\u90e8\u5916\u7528\u6cbb\u7597\u7684\u514b\u7acb\u787c\u7f57\u8f6f\u818f \u7f55\u89c1\u75c5\u9886\u57df \u6cbb\u7597\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684PF-06939926 \u7528\u4e8e\u9002\u5e94\u75c7\u4e3a\u8840\u53cb\u75c5A\u548cB\u7684Marstacimab \u7528\u4e8e\u9002\u5e94\u75c7\u4e3a\u8840\u53cb\u75c5A\u7684Giroctocogene Fitelparvovec \u7528\u4e8e\u9002\u5e94\u75c7\u4e3a\u8840\u53cb\u75c5B\u7684Fidanacogene elaparvovec \u6cbb\u7597\u513f\u7ae5\u8f6f\u9aa8\u53d1\u80b2\u4e0d\u5168\u7684PF-07256472 \u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u8f6c\u7532\u72b6\u817a\u7d20\u86cb\u767d\u6dc0\u7c89\u6837\u53d8\u6027\u591a\u53d1\u6027\u795e\u7ecf\u75c5I\u671f\u75c7\u72b6\u60a3\u8005\uff0c\u5ef6\u7f13\u5468\u56f4\u795e\u7ecf\u529f\u80fd\u635f\u5bb3\u7684\u6c2f\u82ef\u5511\u9178\u8461\u80fa\u8f6f\u80f6\u56ca \u9002\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u91ce\u751f\u578b\u6216\u9057\u4f20\u578b\u8f6c\u7532\u72b6\u817a\u7d20\u86cb\u767d\u6dc0\u7c89\u6837\u53d8\u6027\u5fc3\u808c\u75c5\uff08ATTR-CM\uff09\uff0c\u4ee5\u51cf\u5c11\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u53ca\u5fc3\u8840\u7ba1\u76f8\u5173\u4f4f\u9662\u7684\u6c2f\u82ef\u5511\u9178\u8f6f\u80f6\u56ca \u5185\u79d1\u9886\u57df \u6cbb\u7597\u6210\u4eba\u4e2d\u91cd\u5ea6\u9aa8\u5173\u8282\u708e\u75bc\u75db\uff0c\u7f13\u89e3\u764c\u75db\u7684Tanezumab \u7528\u4e8e2\u578b\u7cd6\u5c3f\u75c5\u3001\u80a5\u80d6\u7684Danuglipron \u7528\u4e8e\u9ad8\u7518\u6cb9\u4e09\u916f\u8840\u75c7\u3001\u964d\u4f4e\u52a8\u8109\u7ca5\u6837\u786c\u5316\u6027\u5fc3\u8840\u7ba1\u75be\u75c5\u60a3\u8005\u7684\u5fc3\u8840\u7ba1\u4e8b\u4ef6\u98ce\u9669\u7684Vupanorsen \u63d0\u53ca\u7b2c\u4e8c\u6b21\u53c2\u5c55\uff0c\u8f89\u745e\u751f\u7269\u5236\u836f\u96c6\u56e2\u4e2d\u56fd\u533a\u5e02\u573a\u8425\u9500\u526f\u603b\u88c1\u738b\u6021\u4eb2\u8868\u793a\uff1a\u201c\u4f5c\u4e3a\u4e00\u4e2a\u5f00\u653e\u3001\u521b\u65b0\u3001\u5408\u4f5c\u7684\u5e73\u53f0\uff0c\u535a\u9ccc\u4e50\u57ce\u2018\u6c38\u4e0d\u843d\u5e55\u2019\u836f\u68b0\u5c55\u5df2\u6210\u4e3a\u63a8\u52a8\u4e2d\u56fd\u533b\u7597\u6c34\u5e73\u63d0\u5347\u548c\u521b\u65b0\u7597\u6cd5\u53ef\u53ca\u7684\u52a0\u901f\u5668\uff0c\u6ee1\u8db3\u4e2d\u56fd\u5e7f\u5927\u60a3\u8005\u6025\u8feb\u7684\u4e34\u5e8a\u6cbb\u7597\u9700\u6c42\u3002\u540c\u65f6\uff0c\u4e5f\u4e3a\u6211\u4eec\u521b\u9020\u4e86\u5f00\u5c55\u5e7f\u6cdb\u5408\u4f5c\u3001\u63a2\u7d22\u521b\u65b0\u4e1a\u52a1\u53d1\u5c55\u6a21\u5f0f\u7684\u5b9d\u8d35\u673a\u4f1a\u3002\u6211\u4eec\u975e\u5e38\u9ad8\u5174\u80fd\u518d\u6b21\u501f\u52a9\u535a\u9ccc\u836f\u68b0\u5c55\u8fd9\u4e2a\u5e73\u53f0\uff0c\u5c55\u793a\u8f89\u745e\u7684\u7a81\u7834\u521b\u65b0\uff0c\u5e76\u901a\u8fc7\u2018\u5148\u884c\u5148\u8bd5\u2019\u653f\u7b56\uff0c\u66f4\u5feb\u83b7\u5f97\u771f\u5b9e\u4e16\u754c\u4e34\u5e8a\u8bc1\u636e\uff0c\u63a8\u52a8\u4ea7\u54c1\u65e9\u65e5\u5728\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\u3002\u201d \u84c4\u529b\u4e2d\u56fd\u521b\u65b0\u4e0e\u5168\u7403\u540c\u6b65 \u8fdb\u5165\u4e2d\u56fd\u5e02\u573a30\u4f59\u5e74\u6765\uff0c\u8f89\u745e\u59cb\u7ec8\u81f4\u529b\u4e8e\u201c\u6210\u4e3a\u4e2d\u56fd\u533b\u7597\u536b\u751f\u4f53\u7cfb\u91cd\u8981\u7ec4\u6210\u90e8\u5206\u201d\uff0c\u5f15\u8fdb\u4e8660\u591a\u4e2a\u521b\u65b0\u836f\u7269\uff0c\u6d89\u53ca\u80bf\u7624\u3001\u75ab\u82d7\u3001\u6297\u611f\u67d3\u3001\u708e\u75c7\u4e0e\u514d\u75ab\u3001\u7f55\u89c1\u75c5\u7b49\u4e94\u5927\u9886\u57df\uff0c\u5e76\u57282019\u5e74\u63d0\u51fa\u4e86\u52a9\u529b\u4e2d\u56fd\u672c\u571f\u7684\u4e34\u5e8a\u7814\u7a76\u8d70\u5411\u5168\u7403\u7684\u91cf\u5316\u76ee\u6807\uff1a\u201c80%&amp;80%\u201d\uff0c\u5373\u52302022\u5e74\uff0c\u5b9e\u73b0\u4e2d\u56fd\u53c2\u52a080%\u7684\u5168\u7403\u65e9\u671f\u4ee5\u53ca\u5173\u952e\u4e09\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5176\u4e2d80%\u7684\u9879\u76ee\u505a\u5230\u540c\u671f\u7533\u62a5\u3002 \u8f89\u745e\uff08\u4e2d\u56fd\uff09\u7814\u7a76\u5f00\u53d1\u6709\u9650\u516c\u53f8\u603b\u7ecf\u7406\u9648\u671d\u534e\u8868\u793a\uff1a\u201c\u79d1\u5b66\u4e0d\u5206\u56fd\u754c\uff0c\u8f89\u745e\u59cb\u7ec8\u81f4\u529b\u4e8e\u79d1\u5b66\u7814\u7a76\uff0c\u6211\u4eec\u575a\u6301\u6295\u5165\u5e76\u4e0d\u65ad\u4f18\u5316\u8d44\u6e90\uff0c\u65e0\u8bba\u662f\u4e2d\u56fd\u60a3\u8005\u8fd8\u662f\u5168\u7403\u60a3\u8005\uff0c\u90fd\u80fd\u591f\u901a\u8fc7\u8f89\u745e\u7684\u79d1\u5b66\u4ea7\u51fa\u83b7\u76ca\u3002\u4e3a\u60a3\u8005\u5e26\u6765\u6539\u53d8\u5176\u751f\u6d3b\u7684\u7a81\u7834\u521b\u65b0\u4e00\u76f4\u90fd\u662f\u6211\u4eec\u7684\u76ee\u6807\u3002\u622a\u81f32021\u5e742\u6708\uff0c\u8f89\u745e\u5168\u7403\u5171\u670995\u4e2a\u521b\u65b0\u836f\u7814\u53d1\u9879\u76ee\u6b63\u5728\u5feb\u901f\u63a8\u8fdb\u4e2d\u3002\u51ed\u501f\u6df1\u539a\u7684\u751f\u7269\u5236\u836f\u7814\u53d1\u5e95\u8574\uff0c\u4ee5\u53ca\u6df1\u8015\u4e2d\u56fd30\u4f59\u5e74\u7684\u7ecf\u9a8c\u79ef\u7d2f\uff0c\u8f89\u745e\u7cbe\u51c6\u6d1e\u5bdf\u4e2d\u56fd\u60a3\u8005\u7684\u9700\u6c42\uff0c\u6c47\u96c6\u5168\u7403\u8d44\u6e90\uff0c\u5e0c\u671b\u4e0e\u6211\u4eec\u7684\u836f\u653f\u7ba1\u7406\u90e8\u95e8\u53ca\u4e34\u5e8a\u7814\u7a76\u4e13\u5bb6\u4eec\u7ee7\u7eed\u901a\u529b\u5408\u4f5c\uff0c\u5c06\u5168\u7403\u540c\u671f\u7814\u53d1\u7684first-in-class\u3001best-in-class\u4ea7\u54c1\u5feb\u901f\u5f15\u5165\u4e2d\u56fd\uff0c\u57282022\u5e74\u5b9e\u73b0\u201880%&amp;80%\u2019\u7684\u76ee\u6807\uff0c\u8ba9\u4e2d\u56fd\u60a3\u8005\u5c3d\u65e9\u83b7\u5f97\u5168\u7403\u7684\u7a81\u7834\u521b\u65b0\u6cbb\u7597\uff0c\u4e3a\u5b9e\u73b0\u5065\u5eb7\u4e2d\u56fd2030\u6218\u7565\u76ee\u6807\u4f5c\u51fa\u6211\u4eec\u7684\u8d21\u732e\u3002\u201d&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2021041321070026429\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":26432,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-26429","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/26429","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=26429"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/26429\/revisions"}],"predecessor-version":[{"id":26431,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/26429\/revisions\/26431"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/26432"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=26429"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=26429"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=26429"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}