{"id":24437,"date":"2021-03-26T18:35:00","date_gmt":"2021-03-26T11:35:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021032618350024437"},"modified":"2021-03-26T21:40:10","modified_gmt":"2021-03-26T13:40:10","slug":"%e8%af%ba%e8%af%9a%e5%81%a5%e5%8d%8e%e5%8f%91%e5%b8%832020%e5%b9%b4%e5%85%a8%e5%b9%b4%e4%b8%9a%e7%bb%a9%e6%8a%a5%e5%91%8a%e5%92%8c%e5%85%ac%e5%8f%b8%e8%bf%9b%e5%b1%95","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021032618350024437","title":{"rendered":"\u8bfa\u8bda\u5065\u534e\u53d1\u5e032020\u5e74\u5168\u5e74\u4e1a\u7ee9\u62a5\u544a\u548c\u516c\u53f8\u8fdb\u5c55"},"content":{"rendered":"<p><p>\u5317\u4eac2021\u5e743\u670826\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u8bfa\u8bda\u5065\u534e\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a09969\uff09\u4eca\u65e5\u53d1\u5e03\u622a\u81f32020\u5e7412\u670831\u65e5\u76842020\u5e74\u5168\u5e74\u4e1a\u7ee9\u62a5\u544a<span 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style=\"text-decoration: underline\">\u5173\u952e\u4ea7\u54c1\u4eae\u70b9\u548c\u91cd\u8981\u91cc\u7a0b\u7891\u4e8b\u4ef6<\/span><\/strong><\/p>\n<p><strong>\u5965\u5e03\u66ff\u5c3c<\/strong><\/p>\n<ul type=\"disc\">\n<li>2020\u5e7412\u670825\u65e5\uff0c\u5965\u5e03\u66ff\u5c3c\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\uff0c\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\/\u96be\u6cbb\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff08CLL\uff09\/\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08SLL\uff09\u60a3\u8005\u3001\u4ee5\u53ca\u590d\u53d1\/\u96be\u6cbb\u6027\u5957\u7ec6\u80de\u6dcb\u5df4\u7624\uff08MCL\uff09 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\u6297\u4f53 &#8212; MIL-62\u8054\u5408\u7597\u6cd5I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u63a5\u8fd1\u5b8c\u6210\u3002\u521d\u6b65\u4e34\u5e8a\u7ed3\u679c\u4ee4\u4eba\u9f13\u821e\uff0c\u8ba1\u52122021\u5e74\u4e0b\u534a\u5e74\u516c\u5e03\u6570\u636e\u3002<\/li>\n<li>\u5728\u7f8e\u56fd\uff0c\u5965\u5e03\u66ff\u5c3c\u9488\u5bf9\u590d\u53d1\u96be\u6cbbMCL\u7684II\u671f\u8bd5\u9a8c\u5df2\u7ecf\u542f\u52a8\uff0c\u5e76\u5df2\u4e8e2020\u5e74\u7b2c\u56db\u5b63\u5ea6\u83b7\u5f97\u7f8e\u56fdFDA\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u8bc1\u3002<\/li>\n<li>\u5965\u5e03\u66ff\u5c3c\u9488\u5bf9\u591a\u53d1\u6027\u786c\u5316\u75c7\uff08MS\uff09\u5168\u7403II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u7ecf\u542f\u52a8\uff0c\u5305\u62ec\u7f8e\u56fd\u3001\u6b27\u6d32\u548c\u4e2d\u56fd\u3002\u6b64\u5916\uff0c\u5965\u5e03\u66ff\u5c3c\u5df2\u5728\u4e2d\u56fd\u5c31\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\uff08SLE\uff09\u5f00\u59cbIIa\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/li>\n<\/ul>\n<p><strong>ICP-192<\/strong>\uff08gunagratinib\uff09<\/p>\n<ul type=\"disc\">\n<li>Gunagratinib\u5df2\u5728\u4e2d\u56fd\u5b8c\u6210I\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u663e\u793a\u826f\u597d\u7684\u8010\u53d7\u6027\u3002II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u6b63\u5728\u5feb\u901f\u63a8\u8fdb\u4e2d\uff0c30\u540d\u60a3\u8005\u5b8c\u6210\u7ed9\u836f\u3002\u572812\u540dFGF\/FGFR\u57fa\u56e0\u7a81\u53d8\u7684\u60a3\u8005\u4e2d\uff0c\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u4e3a33.3%\uff0c\u5305\u62ec1\u540d\u80c6\u7ba1\u764c\u60a3\u8005\uff08\u53608.3%\uff09\u8fbe\u5230\u5b8c\u5168\u7f13\u89e3\uff08CR\uff09\uff0c3\u540d\u60a3\u8005\uff08\u536025%\uff09\u8fbe\u5230\u90e8\u5206\u7f13\u89e3\uff08PR\uff09\u3002\u75be\u75c5\u63a7\u5236\u7387\uff08DCR\uff09\u4e3a91.7%\uff0812\u540d\u60a3\u8005\u4e2d\u670911\u540d\u5f97\u5230\u63a7\u5236\uff09\u3002<\/li>\n<li>\u5728\u7f8e\u56fd\uff0c\u9996\u540d\u60a3\u8005\u4e8e2021\u5e74\u521d\u5b8c\u6210\u7ed9\u836f\u3002<\/li>\n<\/ul>\n<p><strong>ICP-723<\/strong><\/p>\n<ul type=\"disc\">\n<li>\u6b63\u5728\u4e2d\u56fd\u5f00\u5c55I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4ee5\u8bc4\u4f30ICP-723\u5bf9\u6cbb\u7597\u665a\u671f\u5b9e\u4f53\u80bf\u7624\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u53caPK\u7279\u6027\u3002\u5728I\u671f\u5242\u91cf\u9012\u589e\u7814\u7a76\u4e2d\uff0c\u4e24\u7ec4\u60a3\u8005\uff081\u548c2\u6beb\u514b\uff09\u5df2\u5b8c\u6210\u7ed9\u836f\uff0c\u6240\u6709\u60a3\u8005\u5747\u65e0\u53d1\u73b0\u548c\u6cbb\u7597\u76f8\u5173\u7684\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff08SAE\uff09\uff0c\u4e5f\u6ca1\u6709\u89c2\u5bdf\u5230\u5242\u91cf\u9650\u5236\u6027\u6bd2\u6027\uff08DLT\uff09\u3002\u7b2c3\u7ec4\u60a3\u8005\u7684\u5242\u91cf\u9012\u589e\u81f33\u6beb\u514b\uff0c\u5e76\u5df2\u62db\u52dfNTRK\u57fa\u56e0\u878d\u5408\u60a3\u8005\u4f5c\u6709\u6548\u6027\u8bc4\u4f30\u3002<\/li>\n<\/ul>\n<p>\u8bfa\u8bda\u5065\u534e\u8fd8\u6709\u591a\u6b3eIND\u51c6\u5907\u9636\u6bb5\u5019\u9009\u836f\u7269\uff0c\u516c\u53f8\u6b63\u79ef\u6781\u63a8\u8fdbIND\u7533\u8bf7\u8fdb\u5165\u4e34\u5e8a\u3002<\/p>\n<ul type=\"disc\">\n<li><strong>\u5728\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u9886\u57df\uff0c<\/strong>\u8bfa\u8bda\u5065\u534e\u62e5\u6709ICP-332\u3001ICP-488\u548cICP-490\u3002ICP-332\u662f\u5c0f\u5206\u5b50\u916a\u6c28\u9178\u6fc0\u91762\uff08TYK2\uff09\u6291\u5236\u5242\uff0c\u5c06\u7528\u4e8e\u6cbb\u7597\u94f6\u5c51\u75c5\u7b49\u591a\u79cd\u75be\u75c5\u3002ICP-488\u662fTYK2\u7684\u5047\u6fc0\u9176\u7ed3\u6784\u57df\u7684\u5c0f\u5206\u5b50\u6291\u5236\u5242\uff08JH2\uff09\uff0c\u7528\u4e8e\u6cbb\u7597\u725b\u76ae\u7663\u53ca\u708e\u75c7\u6027\u80a0\u75c5\uff08IBD\uff09\u7b49\u75be\u75c5\u3002ICP-490\u662f\u4e00\u79cd\u514d\u75ab\u8c03\u8282\u5242\uff0c\u901a\u8fc7\u4e0eCRL4<sup>CRBN<\/sup>-E3\u8fde\u63a5\u9176\u590d\u5408\u7269\u76f8\u7ed3\u5408\uff0cICP-490\u53ef\u8bf1\u5bfc\u5305\u62ecIkaros\u548cAiolos\u5728\u5185\u7684\u8f6c\u5f55\u56e0\u5b50\u7684\u6cdb\u7d20\u5316\u548c\u964d\u89e3\u3002<\/li>\n<li><strong>\u5728\u5b9e\u4f53\u7624\u65b9\u9762\uff0c<\/strong>\u8bfa\u8bda\u5065\u534e\u62e5\u6709ICP-189\u3001ICP-033\u548cICP-B03\u3002ICP-189\u662f\u4e00\u79cdSHP2\u53d8\u6784\u6291\u5236\u5242\uff0c\u5bf9\u5176\u4ed6\u78f7\u9178\u9176\u5177\u6709\u5f88\u597d\u7684\u9009\u62e9\u6027\u3002ICP-033\u662f\u4e3b\u8981\u9488\u5bf9\u76d8\u72b6\u86cb\u767d\u7ed3\u6784\u57df\u53d7\u4f531\uff08DDR1\uff09\u53ca\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08VEGFR\uff09\u7684\u591a\u6fc0\u9176\u6291\u5236\u5242\uff0c\u8ba1\u5212\u548c\u514d\u75ab\u7597\u6cd5\u53ca\u5176\u4ed6\u9776\u5411\u836f\u8054\u5408\u6cbb\u7597\u809d\u764c\u3001\u80be\u7ec6\u80de\u764c\u3001\u5927\u80a0\u764c\u53ca\u5176\u4ed6\u5b9e\u4f53\u80bf\u7624\u3002ICP-B03\u662f\u53ef\u5728\u80bf\u7624\u9776\u5411\u91ca\u653e\u7684\u767d\u4ecb\u7d20IL-15\u7684\u524d\u836f\uff0c\u53ef\u4ee5\u9776\u5411\u548c\u6539\u53d8\u80bf\u7624\u5fae\u73af\u5883\u5185\u7684\u514d\u75ab\u7ec6\u80de\u3002<\/li>\n<li><strong>\u5728\u8840\u6db2\u7624\u65b9\u9762\uff0c<\/strong>\u8bfa\u8bda\u5065\u534e\u62e5\u6709ICP-490\u548cICP-248\u3002ICP-248<strong>\u662f<\/strong>\u4e00\u79cdB\u7ec6\u80de\u6dcb\u5df4\u76242\uff08BCL-2\uff09\u9009\u62e9\u6027\u6291\u5236\u5242\u3002ICP-248\u62df\u8054\u5408\u5965\u5e03\u66ff\u5c3c\u4ee5\u6cbb\u7597AML\u3001ALL\u3001FL\u3001CLL\u3001DLBCL\u53ca\u5176\u4ed6\u6076\u6027\u8840\u6db2\u80bf\u7624\u3002<\/li>\n<\/ul>\n<p><strong>\u5176\u4ed6\u516c\u53f8\u6700\u65b0\u53d1\u5c55\u52a8\u6001<\/strong><\/p>\n<ul type=\"disc\">\n<li>\u5f15\u5165\u6218\u7565\u6295\u8d44\u30022021\u5e742\u67083\u65e5\uff0c\u9ad8\u74f4\u8d44\u672c\u6210\u4e3a\u8bfa\u8bda\u5065\u534e\u6218\u7565\u6295\u8d44\u8005\uff0c\u540c\u65f6\u7ef4\u68a7\u8d44\u672c\u7ee7\u7eed\u589e\u6301\u3002\u751f\u7269\u533b\u836f\u884c\u4e1a\u9700\u8981\u6301\u7eed\u7684\u521b\u65b0\u7814\u53d1\u4ee5\u53ca\u8d44\u672c\u7684\u652f\u6301\u3002\u901a\u8fc7\u66f4\u591a\u7684\u8d44\u672c\u52a0\u6301\uff0c\u8bfa\u8bda\u5065\u534e\u81f4\u529b\u4e8e\u7814\u53d1\u51fa\u66f4\u591a\u4f18\u8d28\u521b\u65b0\u836f\uff0c\u9020\u798f\u66f4\u591a\u60a3\u8005\u3002<\/li>\n<li>\u5168\u7403\u5316\u3002\u8bfa\u8bda\u5065\u534e2021\u5e743\u6708\u521d\u4efb\u547d\u4e34\u5e8a\u7ecf\u9a8c\u4e30\u5bcc\u7684\u5f20\u5411\u9633\u535a\u58eb\u4e3a\u516c\u53f8\u9996\u5e2d\u533b\u5b66\u5b98\uff0c\u5176\u529e\u516c\u5730\u70b9\u5728\u7f8e\u56fd\uff0c\u8fdb\u4e00\u6b65\u8868\u660e\u8bfa\u8bda\u5065\u534e\u81f4\u529b\u4e8e\u5168\u7403\u5316\u53d1\u5c55\u7684\u52aa\u529b\u3002<\/li>\n<li>\u63d0\u5347\u5546\u52a1\u62d3\u5c55\uff08BD\uff09\u80fd\u529b\u30022020\u5e7410\u6708\uff0c\u8bfa\u8bda\u5065\u534e\u4efb\u547d\u5728BD\u9886\u57df\u62e5\u6709\u4e30\u5bcc\u7ecf\u9a8c\u7684Manish Tandon\u535a\u58eb\u62c5\u4efb\u5546\u52a1\u62d3\u5c55\u526f\u603b\u88c1\uff0c\u5176\u529e\u516c\u5730\u70b9\u5728\u7f8e\u56fd\uff0c\u8fdb\u4e00\u6b65\u63d0\u5347\u516c\u53f8\u5bf9\u5916\u4e1a\u52a1\u62d3\u5c55\u548c\u5408\u4f5c\u7684\u5b9e\u529b\u3002<\/li>\n<\/ul>\n<p>&ldquo;\u7ecf\u8fc7\u4e94\u5e74\u575a\u5b9e\u800c\u5feb\u901f\u7684\u53d1\u5c55\uff0c\u8bfa\u8bda\u5065\u534e\u5efa\u7acb\u4e86\u4e30\u5bcc\u7684\u4ea7\u54c1\u7ba1\u7ebf\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u6211\u4eec\u4fdd\u6301\u4e86\u8d22\u52a1\u7684\u7a33\u5065\u6027\uff0c\u4e3a\u4e1a\u52a1\u53d1\u5c55\u63d0\u4f9b\u4e86\u826f\u597d\u7684\u4fdd\u8bc1\uff0c&rdquo;\u5d14\u9701\u677e\u535a\u58eb\u8bf4\u3002<\/p>\n<p><strong>\u8d22\u52a1\u4e1a\u7ee9\u6458\u8981<\/strong><\/p>\n<ul type=\"disc\">\n<li>\u516c\u53f8\u6536\u5165\u548c\u5176\u4ed6\u6536\u76ca\u75312019\u5e74\u76841.057\u4ebf\u5143\u589e\u52a0\u81f32020\u5e74\u76842.727\u4ebf\u5143\u3002\u968f\u7740\u5965\u5e03\u66ff\u5c3c\u83b7\u6279\u4e0a\u5e02\uff0c2021\u5e74\u516c\u53f8\u6536\u5165\u6765\u6e90\u5c06\u66f4\u52a0\u591a\u5143\u5316\u3002<\/li>\n<li>\u516c\u53f8\u73b0\u91d1\u548c\u94f6\u884c\u7ed3\u4f59\u75312019\u5e74\u768422.918\u4ebf\u5143\u589e\u52a0\u81f32020\u5e74\u768439.696\u4ebf\u5143\u3002<\/li>\n<li>\u516c\u53f8\u7814\u53d1\u652f\u51fa\u75312019\u5e742.131\u4ebf\u5143\u589e\u52a0\u52302020\u5e74\u76844.028\u4ebf\u5143\u3002<\/li>\n<li>\u516c\u53f8\u4e8f\u635f\u75312019\u5e74\u768421.504\u4ebf\u5143\u51cf\u5c11\u81f32020\u5e74\u76844.643\u4ebf\u5143\uff0c\u5176\u4e2d\u5305\u62ec2019\u5e74\u53ef\u8f6c\u6362\u53ef\u8d4e\u56de\u4f18\u5148\u80a1\uff08\u4e8e\u9996\u6b21\u516c\u5f00\u53d1\u552e\u540e\u8f6c\u6362\u4e3a\u666e\u901a\u80a1\uff09\u7684\u516c\u5141\u4ef7\u503c\u53d8\u52a8\u4e8f\u635f18.14\u4ebf\u5143\uff082020\u5e74\u8be5\u4e8f\u635f\u4e3a1.416\u4ebf\u5143\uff09\u3002<\/li>\n<\/ul>\n<p>\uff08\u6ce8\uff1a\u8d27\u5e01\u4e3a\u4eba\u6c11\u5e01\uff0c\u8bfa\u8bda\u5065\u534e\u8d22\u52a1\u5e74\u5ea6\u6307\u7684\u662f\u67d0\u4e00\u5e74\u76841\u67081\u65e5\u523012\u670831\u65e5\uff09<\/p>\n<p>\u60f3\u8981\u4e86\u89e3\u8bfa\u8bda\u5065\u534e2020\u5e74\u5168\u5e74\u4e1a\u7ee9\u7ee9\u62a5\u544a\u8d22\u52a1\u6570\u636e\uff0c\u656c\u8bf7\u767b\u5f55<a href=\"https:\/\/cn.innocarepharma.com\/cn\/investor-relations\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/cn.innocarepharma.com\/cn\/investor-relations<\/a>&nbsp;&nbsp;\u8fdb\u884c\u67e5\u8be2\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u7535\u8bdd\u4f1a\u8bae\u4fe1\u606f<\/strong><\/p>\n<p>\u8bfa\u8bda\u5065\u534e\u5c06\u5728\u5317\u4eac\u65f6\u95f43\u670829\u65e5\u4e0a\u53489:00\u4e3e\u884c\u7535\u8bdd\u4f1a\u8bae\u3002\u53c2\u52a0\u7535\u8bdd\u4f1a\u8bae\u9700\u63d0\u524d\u6ce8\u518c\u3002\u8be6\u60c5\u5982\u4e0b\uff1a<\/p>\n<p>\u6ce8\u518c\u94fe\u63a5\uff1a<a href=\"http:\/\/apac.directeventreg.com\/registration\/event\/4956225\" rel=\"nofollow noopener\" target=\"_blank\">http:\/\/apac.directeventreg.com\/registration\/event\/4956225<\/a><\/p>\n<p>\u4f1a\u8bae\u4ee3\u7801\uff1a4956225&nbsp;&nbsp; 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href=\"https:\/\/cn.innocarepharma.com\/cn\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/cn.innocarepharma.com\/cn\/<\/a><\/p>\n<div>\n<table class=\"prntblns\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><strong>\u8054\u7cfb\u4eba<\/strong><\/span><\/p>\n<\/td>\n<td class=\"prngen2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><strong>\u5a92\u4f53<\/strong><strong>&nbsp;<\/strong><\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><strong>\u6295\u8d44\u8005<\/strong><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">\u9646\u6625\u534e<\/span><\/p>\n<\/td>\n<td class=\"prngen2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">86-10-66609879<\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">86-10-66609999<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><a class=\"prnews_a\" href=\"https:\/\/prnnj3-irisxe8.prnewswire.local\/ewebeditor\/\" rel=\"nofollow noopener\" target=\"_blank\">chunhua.lu@innocarepharma.com<\/a>&nbsp;<\/span><\/p>\n<\/td>\n<td class=\"prngen2\">\n<p class=\"prnews_p\"><span class=\"prnews_span\"><a class=\"prnews_a\" href=\"https:\/\/prnnj3-irisxe8.prnewswire.local\/ewebeditor\/\" rel=\"nofollow noopener\" target=\"_blank\">ir@innocarepharma.com<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>\u76f8\u5173\u94fe\u63a5 :<\/p>\n<p>https:\/\/cn.innocarepharma.com\/cn\/<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5317\u4eac2021\u5e743\u670826\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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