{"id":23759,"date":"2021-03-22T13:56:00","date_gmt":"2021-03-22T06:56:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021032213560023759"},"modified":"2021-03-22T21:40:53","modified_gmt":"2021-03-22T13:40:53","slug":"%e4%ba%91%e9%a1%b6%e6%96%b0%e8%80%80%e4%bb%8a%e6%97%a5%e5%85%ac%e5%b8%83%e6%88%aa%e6%ad%a2%e8%87%b32020%e5%b9%b412%e6%9c%8831%e6%97%a5%e7%9a%84%e5%85%a8%e5%b9%b4%e4%b8%9a%e7%bb%a9","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021032213560023759","title":{"rendered":"\u4e91\u9876\u65b0\u8000\u4eca\u65e5\u516c\u5e03\u622a\u6b62\u81f32020\u5e7412\u670831\u65e5\u7684\u5168\u5e74\u4e1a\u7ee9"},"content":{"rendered":"<p><p>\u4e0a\u6d772021\u5e743\u670822\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u4e91\u9876\u65b0\u8000\uff08Everest Medicines\uff0cHKEX 1952.HK\uff09\uff0c\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u521b\u65b0\u836f\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u6ee1\u8db3\u5927\u4e2d\u534e\u533a\u4ee5\u53ca\u4e9a\u6d32\u5176\u4ed6\u5e02\u573a\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\uff0c\u4eca\u5929\u516c\u5e032020\u5e74\u5ea6\u8d22\u52a1\u4e1a\u7ee9\u62a5\u544a\uff08\u622a\u81f32020\u5e7412\u670831\u65e5\uff09\u53ca\u4e1a\u52a1\u8fdb\u5c55\u3002<\/p>\n<p>\u4e91\u9876\u65b0\u8000\u9996\u5e2d\u6267\u884c\u5b98\u8584\u79d1\u745e\u535a\u58eb\u8868\u793a\uff1a\u201c\u5c3d\u7ba12020\u5e74\u5168\u7403\u906d\u9047\u8bf8\u591a\u5b8f\u89c2\u6311\u6218\u4e0e\u52a8\u8361\uff0c\u4e91\u9876\u65b0\u8000\u4ecd\u7ee7\u7eed\u4fdd\u6301\u957f\u671f\u589e\u957f\u6001\u52bf\uff0c\u8fd9\u5176\u4e2d\u5305\u62ec\u6211\u4eec\u5404\u79cd\u6781\u5177\u524d\u666f\u7684\u521b\u65b0\u5019\u9009\u836f\u7269\u91ca\u653e\u51fa\u7684\u5f3a\u52b2\u52a8\u529b\u3002\u6211\u4eec\u6301\u7eed\u63a8\u8fdb\u5728\u4e3b\u8981\u6cbb\u7597\u9886\u57df\u5019\u9009\u836f\u7269\u7684\u5f00\u53d1\uff0c\u5305\u62ec\u542f\u52a8sacituzumab govitecan-hziy\u5728\u4e24\u79cd\u4e0d\u540c\u4e73\u817a\u764c\u9002\u5e94\u75c7\u7684\u540e\u671f\u9636\u6bb5\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8fd9\u4e24\u79cd\u9002\u5e94\u75c7\u5177\u6709\u5927\u91cf\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\uff1b\u6211\u4eec\u5b8c\u6210\u4e86\u4e00\u98793\u671f\u6865\u63a5\u8bd5\u9a8c\uff0c\u5c31\u5728\u8fd9\u4e2a\u6708\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u53d7\u7406\u4e86\u4f9d\u62c9\u73af\u7d20\uff08eravacycline, Xerava<sup>TM<\/sup>\uff09\u6cbb\u7597\u590d\u6742\u6027\u8179\u8154\u5185\u611f\u67d3\uff08cIAI\uff09\u7684\u836f\u54c1\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7\uff08NDA\uff09\u3002\u540c\u65f6\uff0cNefecon\u5728\u6cbb\u7597IgA\u80be\u75c5\uff08IgAN\uff09\u9886\u57df\u5728\u4e2d\u56fd\u88ab\u7eb3\u5165<span id=\"spanHghlt1b30\">\u2018<\/span>\u7a81\u7834\u6027\u6cbb\u7597\u836f\u7269<span id=\"spanHghlted06\">\u2019<\/span>\uff08BTD\uff09<span id=\"spanHghltb582\">\u3002\u201d<\/span><\/p>\n<p>\u8584\u79d1\u745e\u535a\u58eb\u8868\u793a\uff1a\u201c\u5c55\u671b\u672a\u6765\uff0c\u6211\u4eec\u671f\u76fc2021\u5e74\u5c06\u662f\u4e91\u9876\u65b0\u8000\u66f4\u52a0\u7855\u679c\u7d2f\u7d2f\u7684\u4e30\u6536\u5e74\u3002\u6211\u4eec\u7ee7\u7eed\u805a\u7126\u5728\u4e34\u5e8a\u7814\u53d1\u9879\u76ee\u4e0a\u5353\u8d8a\u7684\u6267\u884c\u529b\uff0c\u4e0e\u6b64\u540c\u65f6\uff0c\u6211\u4eec\u5c06\u628a\u4e91\u9876\u65b0\u8000\u6253\u9020\u4e3a\u4e00\u5bb6\u5546\u4e1a\u5316\u673a\u6784\uff0c\u6211\u4eec\u5728\u5546\u4e1a\u89c4\u5212\u7684\u57fa\u7840\u4e0a\u62d3\u5c55\u56fd\u9645\u4e1a\u52a1\u3001\u836f\u54c1\u751f\u4ea7\u5236\u9020\u4e0e\u65b0\u836f\u53d1\u73b0\u65b9\u9762\u7684\u52aa\u529b\u3002\u6211\u4eec\u5bf9\u4e91\u9876\u65b0\u8000\u4e3a\u60a3\u8005\u548c\u5229\u76ca\u76f8\u5173\u65b9\u521b\u9020\u4ef7\u503c\u5145\u6ee1\u4e86\u4fe1\u5fc3\u3002\u201d<\/p>\n<p><b>\u4e1a\u7ee9\u56de\u987e<\/b><\/p>\n<p>\u81ea\u672c\u516c\u53f8\u4e8e2020\u5e7410\u67089\u65e5\uff08\u4e0a\u5e02\u65e5\u671f\uff09\u5728\u9999\u6e2f\u8054\u5408\u4ea4\u6613\u6240\u6709\u9650\u516c\u53f8\uff08\u8054\u4ea4\u6240\uff09\u4e0a\u5e02\u4ee5\u6765\uff0c\u672c\u96c6\u56e2\u7684\u836f\u54c1\u7ba1\u7ebf\u53ca\u4e1a\u52a1\u8425\u8fd0\u5df2\u53d6\u5f97\u91cd\u5927\u8fdb\u5c55\uff0c\u5305\u62ec\u4e0b\u5217\u91cc\u7a0b\u7891\u53ca\u6210\u5c31\u3002<\/p>\n<p><b><i>Sacituzumab govitecan-hziy \uff08Trodelvy<sup>TM<\/sup>\uff09<\/i><\/b>\u4e3a<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u80bf\u7624\u6cbb\u7597\u9886\u57df\u4e2d\u7684\u652f\u67f1\u5019\u9009\u836f\u7269\uff0c\u662f\u540c\u7c7b\u9996\u521b\u7684TROP-2\u9776\u5411\u6297\u4f53\u836f\u7269\u5076\u8054\u7269\uff08ADC\uff09\u4ea7\u54c1&nbsp;\u3002<\/p>\n<ul type=\"disc\">\n<li>\u62a5\u544a\u671f\u5185\u7684\u5f00\u53d1\u6210\u5c31\uff1a<\/li>\n<\/ul>\n<p id=\"indentid\" class=\"prnml40\">\u4e8e<span id=\"spanHghlt40b3\">2020\u5e7411\u67082\u65e5<\/span>\uff0c\u4e2d\u56fd\u56fd\u5bb6\u836f\u76d1\u5c40\u6279\u51c6sacituzumab govitecan-hziy\u8fdb\u884c\u533a\u57df\u60273 \u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\uff08\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\uff09EVER-132-002 \u7684\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c\u8fd9\u9879\u8bd5\u9a8c\u65e8\u5728\u8bc4\u4f30\u548c\u6bd4\u8f83sacituzumab govitecan-hziy\u4e0e\u533b\u751f\u9009\u62e9\u7597\u6cd5\u5728\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e24\u79cd\u4f46\u4e0d\u8d85\u8fc7\u56db\u79cd\u65e2\u5f80\u5316\u7597\u65b9\u6848\u7684\u6fc0\u7d20\u53d7\u4f53\u9633\u6027\u3001HER2\u9634\u6027\u8f6c\u79fb\u6027\u4e73\u817a\u764c\uff08HR+\/HER2- mBC\uff09\u7684\u4e9a\u6d32\u60a3\u8005\u4e2d\u7684\u6709\u6548\u6027\u53ca\u5b89\u5168\u6027\u3002\u8be5\u8bd5\u9a8c\u5c06\u5728\u4e2d\u56fd\u5927\u9646\u3001\u4e2d\u56fd\u53f0\u6e7e\u53ca\u97e9\u56fd\u62db\u52df\u7ea6330\u540dHR+\/HER2-mBC\u60a3\u8005\u3002\u4e8e2020\u5e7412\u67089\u65e5\uff0c\u8be53\u671f\u7814\u7a76\u5b8c\u6210\u9996\u4f8b\u60a3\u8005\u7ed9\u836f\u3002&nbsp;<\/p>\n<p id=\"indentid\" class=\"prnml40\">\u4e8e2020\u5e7411\u67083\u65e5\uff0csacituzumab govitecan-hziy\u7528\u4e8e\u6cbb\u7597\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e24\u79cd\u65e2\u5f80\u6cbb\u7597\u7684\u8f6c\u79fb\u6027\u4e09\u9634\u6027\u4e73\u817a\u764c\uff08mTNBC\uff09\u4e2d\u56fd2b\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8cEVER-132-001\u5b8c\u6210\u9996\u4f8b\u60a3\u8005\u7ed9\u836f\u3002EVER-132-001\u5c06\u4e8e\u4e2d\u56fd\u62db\u52df\u7ea680\u540dmTNBC\u60a3\u8005\u3002\u503c\u5f97\u4e00\u63d0\u7684\u662fsacituzumab govitecan-hziy\u4ea6\u5df2\u88ab\u7eb3\u5165\u7531\u4e2d\u56fd\u7684\u56fd\u5bb6\u80bf\u7624\u8d28\u63a7\u4e2d\u5fc3\u4e73\u817a\u764c\u4e13\u5bb6\u59d4\u5458\u4f1a\u3001\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u4e73\u817a\u764c\u4e13\u4e1a\u59d4\u5458\u4f1a\u3001\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u80bf\u7624\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u4e13\u4e1a\u59d4\u5458\u4f1a\u5171\u540c\u7f16\u64b0\u7684\u6700\u65b0\u66f4\u65b0\u76842020\u7248\u300a\u665a\u671f\u4e73\u817a\u764c\u89c4\u8303\u8bca\u7597\u6307\u5357\u300b\u3002<\/p>\n<ul type=\"disc\">\n<li>\u62a5\u544a\u671f\u540e\uff08\u9884\u671f\uff09\u91cc\u7a0b\u7891\u53ca\u6210\u7ee9\uff1a<\/li>\n<\/ul>\n<p id=\"indentid\" class=\"prnml40\">\u4e8e2021\u5e741\u67086\u65e5\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u5df2\u5411\u65b0\u52a0\u5761\u536b\u751f\u79d1\u5b66\u5c40\uff08HAS\uff09\u63d0\u4ea4sacituzumab govitecan-hziy\u7528\u4e8e\u6cbb\u7597\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e24\u79cd\u65e2\u5f80\u6cbb\u7597\u7684mTNBC\u60a3\u8005\u7684NDA\u3002&nbsp;<\/p>\n<p id=\"indentid\" class=\"prnml40\">\u4e8e<span id=\"spanHghlt77f8\">2021\u5e741\u67086\u65e5<\/span>\uff0c\u4e2d\u56fd\u56fd\u5bb6\u836f\u76d1\u5c40\u836f\u54c1\u8bc4\u5ba1\u4e2d\u5fc3\u6279\u51c6sacituzumab govitecan-hziy \u7528\u4e8e\u6cbb\u7597\u8f6c\u79fb\u6027\u5c3f\u8def\u4e0a\u76ae\u764c\uff08mUC\uff09\u60a3\u8005\u7684\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u3002&nbsp;\u4f34\u968f\u6b64\u6b21\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c&nbsp;\u4f5c\u4e3a\u5168\u7403<span id=\"spanHghlt2be3\">3\u671f<\/span>TROPiCS-<span id=\"spanHghlt315a\">04\u8bd5<\/span>\u9a8c\u7684\u4e00\u90e8\u5206\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u8ba1\u5212\u5728\u4e2d\u56fd\u4e3a\u8fd9\u9879<span id=\"spanHghlt2583\">3\u671f<\/span>\u3001\u5168\u7403\u591a\u4e2d\u5fc3\u3001\u5f00\u653e\u6807\u7b7e\u3001\u968f\u673a\u4e34\u5e8a\u8bd5\u9a8c\u62db\u52df\u60a3\u8005\u3002&nbsp;\u8be5\u4e34\u5e8a\u8bd5\u9a8c\u65e8\u5728\u5bf9\u7ecf\u542b\u94c2\u7c7b\u836f\u7269\u7684\u5316\u7597\u548c\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\u86cb\u767d\u8d281\uff08PD-1\uff09\/\u7a0b\u5e8f\u6027\u6b7b\u4ea1\u914d\u4f531\uff08PD-L1\uff09\u6297\u4f53\u6cbb\u7597\u540e\u4ecd\u53d1\u751f\u75be\u75c5\u8fdb\u5c55\u7684\u8f6c\u79fb\u6027\u6216\u8005\u5c40\u90e8\u665a\u671f\u4e0d\u53ef\u5207\u9664\u7684\u5c3f\u8def\u4e0a\u76ae\u764c\u60a3\u8005\u4e2d\u5bf9sacituzumab govitecan-hziy\u4e0e\u6807\u51c6\u5316\u7597\u8fdb\u884c\u8bc4\u4f30\u6bd4\u8f83\u3002\u53d7\u8bd5\u8005\u5c06\u968f\u673a\u5165\u7ec4\u81f3sacituzumab govitecan-hziy\u7ec4\u6216\u533b\u751f\u9009\u62e9\u7597\u6cd5\u7ec4\uff08\u5305\u62ec\u7d2b\u6749\u9187\u3001\u591a\u897f\u4ed6\u8d5b\u548c\u957f\u6625\u6c1f\u5b81\uff09\u3002<\/p>\n<p id=\"indentid\" class=\"prnml40\"><span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u9884\u671f\u5c06\u4e8e2021\u5e74\u4e0b\u534a\u5e74\u53d6\u5f97EVER-132-001\u7528\u4e8emTNBC\u7684\u4e2d\u56fd2b\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\u5173\u952e\u6027\u6570\u636e\u5206\u6790\u7ed3\u679c\uff0c\u5e76\u4e14\u5728\u4e2d\u56fd\u542f\u52a8\u60a3\u8005\u62db\u52df\uff0c\u4f5c\u4e3a\u5168\u74033\u671f\u9488\u5bf9\u8f6c\u79fb\u6027\u5c3f\u8def\u4e0a\u76ae\u764c\uff08mUC\uff09\u7684TROPiCS-04\u4e34\u5e8a\u8bd5\u9a8c\u7684\u4e00\u90e8\u5206\u3002<\/p>\n<p id=\"indentid\" class=\"prnml40\"><span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u7684\u5408\u4f5c\u65b9Gilead Sciences\uff0cInc.\uff08Gilead\uff09\u9884\u8ba1\u4e8e2021\u5e74\u4e0a\u534a\u5e74\u83b7\u5f97\u7f8e\u56fdFDA\u5168\u9762\u6279\u51c6mTNBC\u53ca\u7f8e\u56fdFDA\u9488\u5bf9\u6cbb\u7597mUC\u7684\u52a0\u901f\u5ba1\u6279\uff0c\u4ee5\u53ca\u4e8e2021\u5e74\u4e0b\u534a\u5e74\u53d1\u5e03\u5168\u74033\u671fTROPiCS-02\u4e34\u5e8a\u8bd5\u9a8c\u9488\u5bf9HR+\/HER2-mBC\u7684\u5173\u952e\u6027\u6570\u636e\u5206\u6790\u7ed3\u679c\u30021\u671fTROPiCS-03\u7bee\u5b50\u7814\u7a76\u7ee7\u7eed\u8fdb\u884c\uff0cGilead\u9884\u8ba1\u5c06\u4e8e2021\u5e74\u4e0b\u534a\u5e74\u63d0\u4f9b\u6700\u65b0\u6570\u636e\uff0c\u7279\u522b\u662f\u5728\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u65b9\u9762\u3002&nbsp;<\/p>\n<p><b><i>Nefecon<\/i><\/b><i>\u4e3a<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u5fc3\u80be\u6cbb\u7597\u9886\u57df\u4e2d\u7684\u652f\u67f1\u5019\u9009\u836f\u7269\uff0c\u662f\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597<\/i><i>IgA<\/i><i>\u80be\u75c5\u7684\u5e03\u5730\u5948\u5fb7\u65b0\u578b\u53e3\u670d\u5236\u5242\u4ea7\u54c1\u3002<\/i><\/p>\n<ul type=\"disc\">\n<li>\u62a5\u544a\u671f\u5185\u7684\u5f00\u53d1\u6210\u5c31\uff1a<\/li>\n<\/ul>\n<p id=\"indentid\" class=\"prnml40\">\u4e8e2020\u5e7411\u670810\u65e5\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u7684\u8bb8\u53ef\u4f19\u4f34Calliditas\u62a5\u544a\u4e86\u5168\u74033\u671f\u4e34\u5e8a\u8bd5\u9a8cNefIgArd <span id=\"spanHghlt5512\">A\u90e8<\/span>\u5206\u83b7\u5f97\u826f\u597d\u7684\u5173\u952e\u6027\u6570\u636e\u5206\u6790\u7ed3\u679c\uff0c\u8be5\u8bd5\u9a8c\u5206\u6790\u4e86Nefecon\u5bf9\u6bd4\u5b89\u6170\u5242\u6cbb\u7597<span id=\"spanHghlt99d9\">199\u4f8b<\/span>\u539f\u53d1\u6027IgA\u80be\u75c5\u60a3\u8005\u7684\u7597\u6548\u3002\u8be5\u8bd5\u9a8c\u8fbe\u5230\u4e86\u5176\u4e3b\u8981\u76ee\u6807\uff0c\u7ed3\u679c\u663e\u793a\u5728\u6cbb\u7597<span id=\"spanHghlt3655\">9\u4e2a<\/span>\u6708\u540e\uff0c\u60a3\u8005\u7684\u5c3f\u86cb\u767d\u808c\u9150\u6bd4\u7387\uff08\u6216\u86cb\u767d\u5c3f\uff09\u5728\u7edf\u8ba1\u5b66\u4e0a\u663e\u8457\u964d\u4f4e\uff0c\u5728\u6cbb\u759712\u4e2a\u6708\u540e\uff0c\u6709\u4e86\u663e\u8457\u7684\u6301\u7eed\u6027\u6539\u5584\u3002\u8be5\u8bd5\u9a8c\u8fd8\u8fbe\u5230\u4e86\u5173\u952e\u7684\u6b21\u8981\u7ec8\u70b9- \u663e\u793a\u6cbb\u75979\u4e2a\u6708\u540e\uff0c&nbsp;\u5373\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\uff0c\u60a3\u8005\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\u6216eGFR\u4f30\u8ba1\u503c\u5b58\u5728\u7edf\u8ba1\u5b66\u4e0a\u7684\u663e\u8457\u5dee\u5f02\u3002\u7597\u6548\u6570\u636e\u4e5f\u8868\u660e\uff0c\u5728\u4e0e\u8fdb\u5c55\u4e3a\u7ec8\u672b\u671f\u80be\u75c5\u76f8\u5173\u7684\u5173\u952e\u56e0\u7d20\u4e0a\u5177\u6709\u663e\u8457\u4e14\u6709\u76ca\u7684\u6548\u679c\u3002\u6b64\u5916\uff0c\u7ed3\u679c\u663e\u793aNefecon\u7684\u8010\u53d7\u6027\u666e\u904d\u826f\u597d\u3002&nbsp;<\/p>\n<p id=\"indentid\" class=\"prnml40\">\u4e8e2020\u5e7412\u67082\u65e5\uff0c\u4e2d\u56fd\u56fd\u5bb6\u836f\u76d1\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\u516c\u793a\u5e76\u4e8e\u5176\u540e\u6388\u4e88Nefecon\u4e3a\u7528\u4e8e\u6cbb\u7597IgA\u80be\u75c5\u7684\u7a81\u7834\u6027\u6cbb\u7597\u836f\u7269\u3002\u4f5c\u4e3aNefIgArd\u5168\u74033\u671f\u6ce8\u518c\u6027\u7814\u7a76\u7684\u4e00\u90e8\u5206\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u76ee\u524d\u6b63\u5728\u62db\u52df\u60a3\u8005\uff0c\u4ee5\u652f\u6301Nefecon\u5728\u4e2d\u56fd\u7684\u6ce8\u518c\u5ba1\u6279\u3002<\/p>\n<ul type=\"disc\">\n<li>\u62a5\u544a\u671f\u540e\uff08\u9884\u671f\uff09\u91cc\u7a0b\u7891\u53ca\u6210\u7ee9\uff1a<\/li>\n<\/ul>\n<p id=\"indentid\" class=\"prnml40\"><span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u9884\u671f\u4e8e2021\u5e74\u4e0a\u534a\u5e74\u5b8c\u6210NeflgArd\u7528\u4e8eIgA\u80be\u75c5\u7684\u5168\u74033\u671f\u6ce8\u518c\u6027\u7814\u7a76\u7684\u4e2d\u56fd\u60a3\u8005\u62db\u52df\u3002&nbsp;<\/p>\n<p>\u4f9d\u62c9\u73af\u7d20\uff08eravacycline, Xerava<sup>TM<\/sup>\uff09\u662f\u4e00\u79cd\u65b0\u578b\u3001\u5168\u5408\u6210\u3001\u542b\u6c1f\u56db\u73af\u7d20\u7c7b\u9759\u8109\u6ce8\u5c04\u6297\u751f\u7d20\uff0c\u662f\u4e3a\u6cbb\u7597\u591a\u91cd\u8010\u836f\u6027\uff08MDR\uff09\u611f\u67d3\uff08\u5305\u62ecMDR\u9769\u5170\u6c0f\u9634\u6027\u611f\u67d3\uff09\u4e00\u7ebf\u7ecf\u9a8c\u5355\u836f\u6cbb\u7597\u800c\u5f00\u53d1\u7684\u4ea7\u54c1\u3002<\/p>\n<ul type=\"disc\">\n<li>\u62a5\u544a\u671f\u5185\u7684\u5f00\u53d1\u6210\u5c31\uff1a<\/li>\n<\/ul>\n<p id=\"indentid\" class=\"prnml40\">\u4e8e2020\u5e7410\u670827\u65e5\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u5728\u4e2d\u56fd\u5b8c\u6210\u4e86\u4f9d\u62c9\u73af\u7d20\u7528\u4e8e\u6cbb\u7597cIAI\u76843\u671f\u6865\u63a5\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8bd5\u9a8c\u5171\u62db\u52df\u4e86144\u540d\u60a3\u8005\u3002&nbsp;<\/p>\n<ul type=\"disc\">\n<li>\u62a5\u544a\u671f\u540e\uff08\u9884\u671f\uff09\u91cc\u7a0b\u7891\u53ca\u6210\u7ee9\uff1a<\/li>\n<\/ul>\n<p id=\"indentid\" class=\"prnml40\">\u4e2d\u56fd\u56fd\u5bb6\u836f\u76d1\u5c40\u5df2\u4e8e2021\u5e743\u6708\u53d7\u7406\u4f9d\u62c9\u73af\u7d20\u5728\u4e2d\u56fd\u7528\u4e8e\u6cbb\u7597cIAI\u7684\u836f\u54c1\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7\uff0c\u8fd9\u662f<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u5728\u4e2d\u56fd\u63d0\u4ea4\u7684\u9996\u9879\u836f\u54c1\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7\u3002&nbsp;<\/p>\n<p><b><i>\u5176\u4ed6\u8d44\u4ea7<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li>\u62a5\u544a\u671f\u540e\uff08\u9884\u671f\uff09\u91cc\u7a0b\u7891\u53ca\u6210\u7ee9\uff1a<\/li>\n<\/ul>\n<p id=\"indentid\" class=\"prnml40\"><span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u9884\u671f\u4e8e2021\u5e74\u516c\u5e03Taniborbactam\u7528\u4e8e\u590d\u6742\u6027\u8179\u8154\u5185\u611f\u67d3\uff08cUTI\uff09\u7684\u5168\u74033\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5173\u952e\u6027\u6570\u636e\u5206\u6790\u7ed3\u679c\u3002&nbsp;<\/p>\n<p id=\"indentid\" class=\"prnml40\"><span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u8ba1\u5212\u4e8e2021\u5e74\u4e0b\u534a\u5e74\u542f\u52a8FGF401\u7528\u4e8e\u6cbb\u7597\u809d\u7ec6\u80de\u764c\u7684\u4e2d\u56fd2\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002&nbsp;<\/p>\n<p><b><i>\u516c\u53f8\u53d1\u5c55<\/i><\/b><\/p>\n<p id=\"indentid\" class=\"prnml40\">\u4e8e2021\u5e741\u6708\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u4e0eSpero Therapeutics\u516c\u53f8\u8fbe\u6210\u4e86\u4e00\u9879\u6388\u6743\u5408\u7ea6\u7684\u4fee\u8ba2\uff0c\u6839\u636e\u8be5\u534f\u8bae\u7684\u4fee\u8ba2\u5185\u5bb9\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u5c06\u83b7\u5f97\u5019\u9009\u4ea7\u54c1SPR206\u5728\u5927\u4e2d\u534e\u533a\u3001\u97e9\u56fd\u53ca\u90e8\u5206\u4e1c\u5357\u4e9a\u56fd\u5bb6\u7684\u76f8\u5173\u4e13\u5229\u6743\u76ca\u3002SPR206\u662f\u4e00\u6b3e\u9488\u5bf9MDR\u9769\u5170\u6c0f\u9634\u6027\u83cc\u611f\u67d3\u7684\u521b\u65b0\u6cbb\u7597\u9009\u62e9\uff0c\u76ee\u524d\u4ecd\u5728\u4e34\u5e8a\u5f00\u53d1\u9636\u6bb5\u3002<\/p>\n<p id=\"indentid\" class=\"prnml40\">\u4e8e2021\u5e742\u670818\u65e5\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u59d4\u4efb\u90ed\u6c38\u4e3a\u9996\u5e2d\u5546\u52a1\u5b98\u3002\u90ed\u5148\u751f\u62e5\u6709\u8d85\u8fc722\u5e74\u5728\u591a\u5bb6\u8de8\u56fd\u5236\u836f\u516c\u53f8\u62c5\u4efb\u9886\u5bfc\u53ca\u4e1a\u52a1\u7ba1\u7406\u5de5\u4f5c\u7684\u4e30\u5bcc\u7ecf\u9a8c\u3002&nbsp;<\/p>\n<p id=\"indentid\" class=\"prnml40\">\u6839\u636e\u6052\u751f\u6307\u6570\u6709\u9650\u516c\u53f8\u516c\u5e03\u7684\u6700\u65b0\u6307\u6570\u7cfb\u5217\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u88ab\u7eb3\u5165\u4e3a\u6052\u751f\u7efc\u5408\u6307\u6570\u3001\u6052\u751f\u533b\u7597\u4fdd\u5065\u6307\u6570\u53ca\u6052\u751f\u9999\u6e2f\u4e0a\u5dff\u751f\u7269\u79d1\u6280\u6307\u6570\u6210\u4efd\u80a1\uff0c\u81ea2021\u5e743\u670815\u65e5\u8d77\u751f\u6548\u3002\u83b7\u7eb3\u5165\u4e0a\u8ff0\u6052\u751f\u6307\u6570\u6807\u5fd7\u7740\u672c\u516c\u53f8\u5df2\u7b26\u5408\u4e86\u88ab\u7eb3\u5165\u6e2f\u80a1\u901a\u4ea4\u6613\u7684\u6807\u51c6\uff0c\u800c\u6e2f\u80a1\u901a\u4e3a\u9999\u6e2f\u4e0e\u4e2d\u56fd\u5e7f\u5927\u8d44\u672c\u5e02\u573a\u6295\u8d44\u8005\u4e4b\u95f4\u7684\u80a1\u7968\u4e70\u5356\u4e0e\u6295\u8d44\u7684\u6e20\u9053\u3002<\/p>\n<p>&nbsp;<b><i>\u672a\u6765\u53d1\u5c55<\/i><\/b><\/p>\n<p><span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u5c06\u7ee7\u7eed\u6253\u9020\uff0c\u4ee5\u5927\u4e2d\u534e\u53ca\u4e9a\u592a\u533a\u5176\u4ed6\u5e02\u573a\u4e3a\u8d77\u70b9\u4e13\u6ce8\u4e8e\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u5168\u7403\u521b\u65b0\u7597\u6cd5\u7684\u9876\u5c16\u751f\u7269\u5236\u836f\u516c\u53f8\u3002\u4e3a\u4e86\u8fbe\u6210\u76ee\u6807\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u5c06\u52aa\u529b\u63a8\u8fdb\u53ca\u5b8c\u6210\u73b0\u6709\u5019\u9009\u836f\u7269\u6ce8\u518c\u6027\u8bd5\u9a8c\uff0c\u5e76\u4e14\u5bfb\u6c42\u6700\u5177\u6210\u6548\u7684\u5ba1\u6279\u9014\u5f84\u3002\u4e0e\u6b64\u540c\u65f6\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u5c06\u7ee7\u7eed\u901a\u8fc7\u5f15\u8fdb\u6388\u6743\u53ca\u6253\u9020\u81ea\u6709\u7814\u53d1\u80fd\u529b\uff0c\u6269\u5927\u5728\u6709\u5927\u91cf\u5c1a\u672a\u5f97\u5230\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u7684\u9009\u5b9a\u6cbb\u7597\u9886\u57df\u4e2d\u7684\u521b\u65b0\u836f\u7269\u4ea7\u54c1\u7ec4\u5408\u3002\u4e3a\u652f\u6301\u591a\u6b3e\u5373\u5c06\u4e0a\u5e02\u7684\u540e\u671f\u9636\u6bb5\u4ea7\u54c1\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u5df2\u5f00\u59cb\u7ec4\u5efa\u4e00\u652f\u5728\u4e0d\u540c\u6cbb\u7597\u9886\u57df\u5747\u62e5\u6709\u4e30\u5bcc\u9500\u552e\u3001\u8425\u8fd0\u53ca\u5e02\u573a\u51c6\u5165\u6218\u7565\u77e5\u8bc6\u7684\u5546\u4e1a\u56e2\u961f\u3002\u6b64\u5916\uff0c<span id=\"spanHghlte0a3\">\u4e91\u9876\u65b0\u8000<\/span>\u6b63\u5728\u4e8e\u4e2d\u56fd\u5efa\u7acb\u81ea\u8eab\u7684GMP\/GSP\u751f\u4ea7\u8bbe\u65bd\uff0c\u52a1\u6c42\u786e\u4fdd\u957f\u671f\u7a33\u5b9a\u53ca\u5145\u8db3\u7684\u836f\u7269\u4f9b\u5e94\u53ca\u4f18\u5316\u5546\u54c1\u6210\u672c\u3002&nbsp;<\/p>\n<p><b><i>\u8d22\u52a1\u6458\u8981<\/i><\/b><\/p>\n<p><b><i>\u56fd\u9645\u8d22\u52a1\u62a5\u544a\u51c6\u5219\u6570\u5b57<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li>\u622a\u81f32020\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\uff0c\u672c\u96c6\u56e2\u7684\u7814\u53d1\u5f00\u652f\u7531\u622a\u81f32019\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e01150.9\u767e\u4e07\u5143\u589e\u52a0\u4eba\u6c11\u5e01226.5\u767e\u4e07\u5143\uff0c\u81f3\u4eba\u6c11\u5e01377.4\u767e\u4e07\u5143\uff0c\u4e3b\u8981\u7531\u4e8e<span id=\"spanHghlte0a3\">\u672c\u96c6\u56e2<\/span>\u5bf9\u5019\u9009\u836f\u7269\u5f00\u5c55\u989d\u5916\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u53ca\u62d3\u5c55\u7814\u53d1\u56e2\u961f\u6240\u81f4\u3002&nbsp; <\/li>\n<li>\u622a\u81f32020\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\uff0c\u672c\u96c6\u56e2\u7684\u4e00\u822c\u53ca\u884c\u653f\u5f00\u652f\u7531\u622a\u81f32019\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e0153.9\u767e\u4e07\u5143\u589e\u52a0\u4eba\u6c11\u5e01223.9\u767e\u4e07\u5143\uff0c\u81f3\u4eba\u6c11\u5e01277.8\u767e\u4e07\u5143\uff0c\u4e3b\u8981\u7531\u4e8e\u9996\u6b21\u516c\u5f00\u53d1\u552e\uff08\u9996\u6b21\u516c\u5f00\u53d1\u552e\uff09\u8d39\u7528\u53ca\u7ec4\u7ec7\u56e2\u961f\u6269\u5145\u4ee4\u96c7\u5458\u85aa\u916c\u589e\u52a0\u6240\u81f4\u3002&nbsp; <\/li>\n<li>\u622a\u81f32020\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\uff0c\u5411\u6295\u8d44\u8005\u53d1\u884c\u7684\u91d1\u878d\u5de5\u5177\u516c\u5141\u503c\u53d8\u52a8\u4ea7\u751f\u7684\u4e8f\u635f\u7531\u622a\u81f32019\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e0136.5\u767e\u4e07\u5143\u589e\u52a0\u4eba\u6c11\u5e014,901.5\u767e\u4e07\u5143\uff0c\u81f3\u4eba\u6c11\u5e014,938.0\u767e\u4e07\u5143\uff0c\u4e3b\u8981\u5f52\u56e0\u4e8e\u672c\u516c\u53f8\u5b8c\u6210\u9996\u6b21\u516c\u5f00\u53d1\u552e\u540e\u91cd\u65b0\u8ba1\u91cf\u65e2\u5f80\u53d1\u884c\u4e88\u6295\u8d44\u8005\u7684\u53ef\u8f6c\u6362\u53ef\u8d4e\u56de\u4f18\u5148\u80a1\u65f6\u6bcf\u80a1\u516c\u5141\u503c\u5927\u5e45\u4e0a\u5347\u3002&nbsp; <\/li>\n<li>\u622a\u81f32020\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u5e74\u5185\u4e8f\u635f\u51c0\u989d\uff0c\u7531\u622a\u81f32019\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e01214.5\u767e\u4e07\u5143\uff0c\u589e\u81f3\u4eba\u6c11\u5e015,658.2\u767e\u4e07\u5143\uff0c\u4e3b\u8981\u7531\u4e8e\u5411\u6295\u8d44\u8005\u53d1\u884c\u7684\u91d1\u878d\u5de5\u5177\u516c\u5141\u503c\u53d8\u52a8\u4ea7\u751f\u4e8f\u635f\u4eba\u6c11\u5e014,938.0\u767e\u4e07\u5143\uff0c\u4e43\u6839\u636e\u56fd\u9645\u8d22\u52a1\u62a5\u544a\u51c6\u5219\uff08\u56fd\u9645\u8d22\u52a1\u62a5\u544a\u51c6\u5219\uff09\u89c4\u5b9a\u4e8e\u4e0a\u5e02\u540e\u8fdb\u884c\u7684\u975e\u73b0\u91d1\u4e00\u6b21\u6027\u8c03\u6574\u3002<\/li>\n<\/ul>\n<p><b><i>\u975e\u56fd\u9645\u8d22\u52a1\u62a5\u544a\u51c6\u5219\u8ba1\u91cf\uff1a<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li>\u622a\u81f32020\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u5e74\u5185\u7ecf\u8c03\u6574\u4e8f\u635f<sup><span id=\"spanHghlt08d9\">[1]<\/span><\/sup>\u4e3a\u4eba\u6c11\u5e01602.9\u767e\u4e07\u5143\uff0c\u8f83\u622a\u81f32019\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e01163.1\u767e\u4e07\u5143\u589e\u52a0\u4eba\u6c11\u5e01439.8\u767e\u4e07\u5143\uff0c\u4e3b\u8981\u7531\u4e8e\u7814\u53d1\u5f00\u652f\u53ca\u4e00\u822c\u53ca\u884c\u653f\u5f00\u652f\u589e\u52a0\u6240\u81f4\u3002&nbsp;<\/li>\n<\/ul>\n<p><span id=\"spanHghltaa6a\"><sup>[1]<\/sup> \u5e74\u5185\u7ecf\u8c03\u6574\u4e8f\u635f\u6307\u672a\u8ba1\u53ca\u82e5\u5e72\u975e\u73b0\u91d1\u9879\u76ee\u53ca\u4e00\u6b21\u6027\u4e8b\u4ef6\u5f71\u54cd\u7684\u672c\u516c\u53f8\u6743\u76ca\u6301\u6709\u4eba\u5e94\u5360\u5e74\u5185\u4e8f\u635f\uff0c\u5373\u4f18\u5148\u80a1\u516c\u5141\u503c\u53d8\u52a8\u4ea7\u751f\u7684\u4e8f\u635f\uff08\u6309\u516c\u5141\u503c\u8ba1\u5165\u635f\u76ca\u8ba1\u91cf\u7684\u975e\u6d41\u52a8\u91d1\u878d\u8d1f\u503a\uff09\u53ca\u4ee5\u80a1\u4efd\u4e3a\u57fa\u7840\u7684\u85aa\u916c\u4e8f\u635f\u3002<\/span><\/p>\n<p><b>\u5173\u4e8e\u4e91\u9876\u65b0\u8000<\/b><\/p>\n<p>\u4e91\u9876\u65b0\u8000\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u521b\u65b0\u836f\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u6ee1\u8db3\u5927\u4e2d\u534e\u533a\u53ca\u4e9a\u6d32\u5176\u4ed6\u5e02\u573a\u5c1a\u672a\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u3002\u4e91\u9876\u65b0\u8000\u7684\u7ba1\u7406\u56e2\u961f\u5728\u56fd\u5185\u5916\u9ad8\u8d28\u91cf\u4e34\u5e8a\u5f00\u53d1\u3001\u836f\u653f\u4e8b\u52a1\u3001\u5316\u5b66\u5236\u9020\u4e0e\u63a7\u5236(CMC)\u3001\u4e1a\u52a1\u53d1\u5c55\u548c\u8fd0\u8425\u65b9\u9762\u62e5\u6709\u6df1\u539a\u7684\u4e13\u957f\u548c\u4e30\u5bcc\u7684\u7ecf\u9a8c\u3002\u4e91\u9876\u65b0\u8000\u5df2\u6253\u9020\u4e868\u6b3e\u6709\u6f5c\u529b\u6210\u4e3a\u5168\u7403\u540c\u7c7b\u9996\u521b\u6216\u8005\u540c\u7c7b\u6700\u4f73\u7684\u836f\u7269\u7ec4\u5408\uff0c\u5176\u4e2d\u5927\u90e8\u5206\u5df2\u7ecf\u5904\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u540e\u671f\u9636\u6bb5\u3002\u516c\u53f8\u7684\u6cbb\u7597\u9886\u57df\u5305\u62ec\u80bf\u7624\u3001\u81ea\u4f53\u514d\u75ab\u6027\u75be\u75c5\u3001\u5fc3\u80be\u75be\u75c5\u548c\u611f\u67d3\u6027\u75be\u75c5\u3002\u6709\u5173\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9\uff1a<a target=\"_blank\" href=\"http:\/\/www.everestmedicines.com\/\" rel=\"nofollow noopener\">www.everestmedicines.com<\/a><span id=\"spanHghltaff3\">\u3002<\/span><\/p>\n<p>\u76f8\u5173\u94fe\u63a5 :<\/p>\n<p>http:\/\/www.everestmedicines.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e0a\u6d772021\u5e743\u670822\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u4e91\u9876\u65b0\u8000\uff08Everest Medicines\uff0cHKEX 1952.HK\uff09\uff0c\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u521b\u65b0\u836f\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u6ee1\u8db3\u5927\u4e2d\u534e\u533a\u4ee5\u53ca\u4e9a\u6d32\u5176\u4ed6\u5e02\u573a\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\uff0c\u4eca\u5929\u516c\u5e032020\u5e74\u5ea6\u8d22\u52a1\u4e1a\u7ee9\u62a5\u544a\uff08\u622a\u81f32020\u5e7412\u670831\u65e5\uff09\u53ca\u4e1a\u52a1\u8fdb\u5c55\u3002 \u4e91\u9876\u65b0\u8000\u9996\u5e2d\u6267\u884c\u5b98\u8584\u79d1\u745e\u535a\u58eb\u8868\u793a\uff1a\u201c\u5c3d\u7ba12020\u5e74\u5168\u7403\u906d\u9047\u8bf8\u591a\u5b8f\u89c2\u6311\u6218\u4e0e\u52a8\u8361\uff0c\u4e91\u9876\u65b0\u8000\u4ecd\u7ee7\u7eed\u4fdd\u6301\u957f\u671f\u589e\u957f\u6001\u52bf\uff0c\u8fd9\u5176\u4e2d\u5305\u62ec\u6211\u4eec\u5404\u79cd\u6781\u5177\u524d\u666f\u7684\u521b\u65b0\u5019\u9009\u836f\u7269\u91ca\u653e\u51fa\u7684\u5f3a\u52b2\u52a8\u529b\u3002\u6211\u4eec\u6301\u7eed\u63a8\u8fdb\u5728\u4e3b\u8981\u6cbb\u7597\u9886\u57df\u5019\u9009\u836f\u7269\u7684\u5f00\u53d1\uff0c\u5305\u62ec\u542f\u52a8sacituzumab govitecan-hziy\u5728\u4e24\u79cd\u4e0d\u540c\u4e73\u817a\u764c\u9002\u5e94\u75c7\u7684\u540e\u671f\u9636\u6bb5\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8fd9\u4e24\u79cd\u9002\u5e94\u75c7\u5177\u6709\u5927\u91cf\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\uff1b\u6211\u4eec\u5b8c\u6210\u4e86\u4e00\u98793\u671f\u6865\u63a5\u8bd5\u9a8c\uff0c\u5c31\u5728\u8fd9\u4e2a\u6708\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u53d7\u7406\u4e86\u4f9d\u62c9\u73af\u7d20\uff08eravacycline, XeravaTM\uff09\u6cbb\u7597\u590d\u6742\u6027\u8179\u8154\u5185\u611f\u67d3\uff08cIAI\uff09\u7684\u836f\u54c1\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7\uff08NDA\uff09\u3002\u540c\u65f6\uff0cNefecon\u5728\u6cbb\u7597IgA\u80be\u75c5\uff08IgAN\uff09\u9886\u57df\u5728\u4e2d\u56fd\u88ab\u7eb3\u5165\u2018\u7a81\u7834\u6027\u6cbb\u7597\u836f\u7269\u2019\uff08BTD\uff09\u3002\u201d 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govitecan-hziy\u4e0e\u6807\u51c6\u5316\u7597\u8fdb\u884c\u8bc4\u4f30\u6bd4\u8f83\u3002\u53d7\u8bd5\u8005\u5c06\u968f\u673a\u5165\u7ec4\u81f3sacituzumab govitecan-hziy\u7ec4\u6216\u533b\u751f\u9009\u62e9\u7597\u6cd5\u7ec4\uff08\u5305\u62ec\u7d2b\u6749\u9187\u3001\u591a\u897f\u4ed6\u8d5b\u548c\u957f\u6625\u6c1f\u5b81\uff09\u3002 \u4e91\u9876\u65b0\u8000\u9884\u671f\u5c06\u4e8e2021\u5e74\u4e0b\u534a\u5e74\u53d6\u5f97EVER-132-001\u7528\u4e8emTNBC\u7684\u4e2d\u56fd2b\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\u5173\u952e\u6027\u6570\u636e\u5206\u6790\u7ed3\u679c\uff0c\u5e76\u4e14\u5728\u4e2d\u56fd\u542f\u52a8\u60a3\u8005\u62db\u52df\uff0c\u4f5c\u4e3a\u5168\u74033\u671f\u9488\u5bf9\u8f6c\u79fb\u6027\u5c3f\u8def\u4e0a\u76ae\u764c\uff08mUC\uff09\u7684TROPiCS-04\u4e34\u5e8a\u8bd5\u9a8c\u7684\u4e00\u90e8\u5206\u3002 \u4e91\u9876\u65b0\u8000\u7684\u5408\u4f5c\u65b9Gilead Sciences\uff0cInc.\uff08Gilead\uff09\u9884\u8ba1\u4e8e2021\u5e74\u4e0a\u534a\u5e74\u83b7\u5f97\u7f8e\u56fdFDA\u5168\u9762\u6279\u51c6mTNBC\u53ca\u7f8e\u56fdFDA\u9488\u5bf9\u6cbb\u7597mUC\u7684\u52a0\u901f\u5ba1\u6279\uff0c\u4ee5\u53ca\u4e8e2021\u5e74\u4e0b\u534a\u5e74\u53d1\u5e03\u5168\u74033\u671fTROPiCS-02\u4e34\u5e8a\u8bd5\u9a8c\u9488\u5bf9HR+\/HER2-mBC\u7684\u5173\u952e\u6027\u6570\u636e\u5206\u6790\u7ed3\u679c\u30021\u671fTROPiCS-03\u7bee\u5b50\u7814\u7a76\u7ee7\u7eed\u8fdb\u884c\uff0cGilead\u9884\u8ba1\u5c06\u4e8e2021\u5e74\u4e0b\u534a\u5e74\u63d0\u4f9b\u6700\u65b0\u6570\u636e\uff0c\u7279\u522b\u662f\u5728\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u65b9\u9762\u3002&nbsp; Nefecon\u4e3a\u4e91\u9876\u65b0\u8000\u5fc3\u80be\u6cbb\u7597\u9886\u57df\u4e2d\u7684\u652f\u67f1\u5019\u9009\u836f\u7269\uff0c\u662f\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597IgA\u80be\u75c5\u7684\u5e03\u5730\u5948\u5fb7\u65b0\u578b\u53e3\u670d\u5236\u5242\u4ea7\u54c1\u3002 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