{"id":23611,"date":"2021-03-22T10:57:00","date_gmt":"2021-03-22T03:57:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021032210570023611"},"modified":"2021-03-22T21:37:04","modified_gmt":"2021-03-22T13:37:04","slug":"%e5%85%a8%e7%90%83%e9%a6%96%e4%b8%aa%e9%bc%bb%e5%92%bd%e7%99%8c%e5%85%8d%e7%96%ab%e6%b2%bb%e7%96%97%e8%8d%af%e7%89%a9-%e6%8b%93%e7%9b%8ar%e6%96%b0%e9%80%82%e5%ba%94%e7%97%87%e5%85%a8%e5%9b%bd","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021032210570023611","title":{"rendered":"\u5168\u7403\u9996\u4e2a\u9f3b\u54bd\u764c\u514d\u75ab\u6cbb\u7597\u836f\u7269-\u62d3\u76ca(R)\u65b0\u9002\u5e94\u75c7\u5168\u56fd\u4e0a\u5e02\u4f1a\u987a\u5229\u4e3e\u529e"},"content":{"rendered":"

\u201c\u65e0\u4e0e\u4f26\u6bd4 \u62d3\u65b0\u60a6\u76ca\u201d<\/span><\/p>\n

\u76f8\u5173\u9002\u5e94\u75c7\u5df2\u540c\u6b65\u5728\u7f8e\u56fd\u63d0\u4ea4\u4e0a\u5e02\u7533\u8bf7<\/span><\/p>\n

\u4e0a\u6d772021\u5e743\u670822\u65e5 \/\u7f8e\u901a\u793e\/ — 2021\u5e743\u670820\u65e5\uff0c\u4f5c\u4e3a\u201c\u541bDREAM·\u6b63\u5f53\u5b9e\u201d\u7b2c\u4e8c\u5c4aCSCO-\u541b\u5b9e\u751f\u7269\u80bf\u7624\u514d\u75ab\u9ad8\u5cf0\u8bba\u575b\u7684\u91cd\u8981<\/span>\u73af\u8282 — \u62d3\u76ca®<\/sup>\u9f3b\u54bd\u764c\u9002\u5e94\u75c7\u5168\u56fd\u4e0a\u5e02\u4f1a\u5728\u5e7f\u5dde\u987a\u5229\u53ec\u5f00\u3002\u4e2d\u5c71\u5927\u5b66\u80bf\u7624\u9632\u6cbb\u4e2d\u5fc3\u5f90\u745e\u534e\u6559\u6388\u548c\u5362\u6cf0\u7965\u6559\u6388\u3001\u798f\u5efa\u7701\u80bf\u7624\u533b\u9662\u6f58\u5efa\u57fa\u6559\u6388\u62c5\u4efb\u5927\u4f1a\u540d\u8a89\u4e3b\u5e2d\uff0c\u56fd\u5185\u767e\u4f59\u4f4d\u9f3b\u54bd\u764c\u3001\u5934\u9888\u90e8\u80bf\u7624\u9886\u57df\u4e13\u5bb6\u3001\u5b66\u8005\u548c\u540c\u9053\u9f50\u805a\u4e00\u5802\uff0c\u63a2\u8ba8\u514d\u75ab\u6cbb\u7597\u7684\u673a\u4f1a\u4e0e\u6311\u6218\uff0c\u540c\u65f6\u5e86\u8d3a\u5168\u7403\u9996\u4e2a\u9f3b\u54bd\u764c\u514d\u75ab\u7597\u6cd5\u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca®<\/sup>\uff09\u65b0\u9002\u5e94\u75c7\u6b63\u5f0f\u5728\u5168\u56fd\u4e0a\u5e02\u3002<\/p>\n

\n

\"\u56fd\u5185\u767e\u4f59\u4f4d\u9f3b\u54bd\u764c\u3001\u5934\u9888\u90e8\u80bf\u7624\u9886\u57df\u4e13\u5bb6\u3001\u5b66\u8005\u548c\u540c\u9053\u9f50\u805a\u4e00\u5802\uff0c\u63a2\u8ba8\u514d\u75ab\u6cbb\u7597\u7684\u673a\u4f1a\u4e0e\u6311\u6218\uff0c\u540c\u65f6\u5e86\u8d3a\u5168\u7403\u9996\u4e2a\u9f3b\u54bd\u764c\u514d\u75ab\u7597\u6cd5\u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca(R)\uff09\u65b0\u9002\u5e94\u75c7\u6b63\u5f0f\u5728\u5168\u56fd\u4e0a\u5e02\"<\/a>
\u56fd\u5185\u767e\u4f59\u4f4d\u9f3b\u54bd\u764c\u3001\u5934\u9888\u90e8\u80bf\u7624\u9886\u57df\u4e13\u5bb6\u3001\u5b66\u8005\u548c\u540c\u9053\u9f50\u805a\u4e00\u5802\uff0c\u63a2\u8ba8\u514d\u75ab\u6cbb\u7597\u7684\u673a\u4f1a\u4e0e\u6311\u6218\uff0c\u540c\u65f6\u5e86\u8d3a\u5168\u7403\u9996\u4e2a\u9f3b\u54bd\u764c\u514d\u75ab\u7597\u6cd5\u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca(R)\uff09\u65b0\u9002\u5e94\u75c7\u6b63\u5f0f\u5728\u5168\u56fd\u4e0a\u5e02<\/span><\/p>\n<\/p><\/div>\n

\u7279\u745e\u666e\u5229\u5355\u6297\u7531\u541b\u5b9e\u751f\u7269\u81ea\u4e3b\u7814\u53d1\uff0c\u662f\u4e00\u6b3e\u91cd\u7ec4\u4eba\u6e90\u5316\u6297PD-1\u5355\u514b\u9686\u6297\u4f53\u6ce8\u5c04\u6db2\uff0c\u81ea\u9762\u4e16\u4ee5\u6765\u5c31\u4e0d\u65ad\u5237\u65b0\u7740\u201c\u7b2c\u4e00\u201d\u30022018\u5e7412\u6708\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u4f5c\u4e3a\u6211\u56fd\u9996\u4e2a<\/b>\u56fd\u4ea7\u6297PD-1\u5355\u6297\u836f\u7269\u83b7\u6279\u4e0a\u5e02\uff0c\u7528\u4e8e\u65e2\u5f80\u63a5\u53d7\u5168\u8eab\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u7684\u6cbb\u7597\u30022021\u5e742\u6708\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u201c\u518d\u4e0b\u4e00\u57ce\u201d\uff0c\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\uff0c\u7528\u4e8e\u65e2\u5f80\u63a5\u53d7\u8fc7\u4e8c\u7ebf\u53ca\u4ee5\u4e0a\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u7684\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\u7684\u6cbb\u7597\uff0c\u6210\u4e3a\u5168\u7403\u9996\u4e2a<\/b>\u83b7\u6279\u9f3b\u54bd\u764c\u6cbb\u7597\u7684\u6297PD-1\u5355\u6297\u836f\u7269\uff0c\u5b9e\u73b0\u4e86\u8be5\u9886\u57df\u5185\u514d\u75ab\u6cbb\u7597\u96f6\u7684\u7a81\u7834\u3002\u7d27\u63a5\u77402021\u5e743\u6708\uff0c\u541b\u5b9e\u751f\u7269\u53c8\u518d\u63a5\u518d\u5389\uff0c\u5411\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6eda\u52a8\u63d0\u4ea4\u4e86\u7279\u745e\u666e\u5229\u5355\u6297\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7\u3002\u7279\u745e\u666e\u5229\u5355\u6297\u6210\u4e3a\u9996\u4e2a<\/b>\u5411\u7f8e\u56fdFDA\u63d0\u4ea4\u4e0a\u5e02\u7533\u8bf7\u7684\u56fd\u4ea7\u6297PD-1\u5355\u6297\u3002<\/p>\n

\u6b64\u6b21\u83b7\u6279\u57fa\u4e8e\u4e00\u9879\u591a\u4e2d\u5fc3\u3001\u5f00\u653e\u6807\u7b7e\u3001II\u671f\u5173\u952e\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76\uff08POLARIS-02\u7814\u7a76\uff0cNCT02915432\uff09\uff0c\u5171\u7eb3\u5165190\u4f8b\u65e2\u5f80\u63a5\u53d7\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u7684\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\uff0c\u662f\u8fc4\u4eca\u4e3a\u6b62\u5168\u7403\u8303\u56f4\u5185\u5df2\u5b8c\u6210\u7684\u6700\u5927\u89c4\u6a21<\/b>\u7684\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u5355\u836f\u6cbb\u7597\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684\u4e34\u5e8a\u8bd5\u9a8c\u3002POLARIS-02\u7814\u7a76\u6210\u679c\u66fe\u9891\u9891\u4eae\u76f8\u56fd\u9645\u5b66\u672f\u821e\u53f0\uff0c\u5148\u540e\u5165\u9009\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\uff08ESMO\uff09\u5e74\u4f1a\u3001\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\uff0c\u5e76\u6700\u7ec8\u6536\u5f55\u5728\u300a\u4e34\u5e8a\u80bf\u7624\u5b66\u6742\u5fd7\u300b\uff08Journal of Clinical Oncology<\/i>\uff0cIF: 32.956\uff09\u3002\u7279\u745e\u666e\u5229\u5355\u6297\u8fd8\u51ed\u501f\u8fd9\u9879\u7814\u7a76\u83b7\u5f97\u4e86\u7f8e\u56fdFDA\u6388\u4e88\u7684\u5b64\u513f\u836f\u8d44\u683c\u548c\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u8fd9\u4e5f\u662f\u4e2d\u56fd\u6297\u4f53\u7c7b\u836f\u7269\u7b2c\u4e00\u6b21\u83b7\u5f97FDA\u7684\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u3002<\/p>\n

POLARIS-02\u7684\u4e3b\u8981\u7814\u7a76\u8005\u4e2d\u5c71\u5927\u5b66\u80bf\u7624\u9632\u6cbb\u4e2d\u5fc3\u9662\u957f\u5f90\u745e\u534e\u6559\u6388<\/b>\u5728\u5927\u4f1a\u81f4\u8f9e\u4e2d\u5bf9\u7279\u745e\u666e\u5229\u5355\u6297\u65b0\u9002\u5e94\u75c7\u7684\u4e0a\u5e02\u8868\u793a\u795d\u8d3a\uff0c\u5145\u5206\u80af\u5b9a\u4e86\u6211\u56fd\u7814\u53d1\u4eba\u5458\u3001\u7814\u7a76\u8005\u548c\u60a3\u8005\u4e3a\u5168\u7403\u9f3b\u54bd\u764c\u6cbb\u7597\u7684\u53d1\u5c55\u505a\u51fa\u7684\u8d21\u732e\u3002<\/p>\n

\u201c\u4e2d\u56fd\u662f\u5168\u7403\u9f3b\u54bd\u764c\u60a3\u8005\u6700\u591a\u7684\u56fd\u5bb6\uff0c\u867d\u7136\u65e9\u671f\u9f3b\u54bd\u764c\u6cbb\u7597\u6548\u679c\u5c1a\u53ef\uff0c\u4f46\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684\u6574\u4f53\u4e34\u5e8a\u9884\u540e\u4e0d\u4f73\uff0c\u56e0\u6b64\u5bfb\u6c42\u66f4\u597d\u7684\u6cbb\u7597\u624b\u6bb5\u662f\u665a\u671f\u9f3b\u54bd\u764c\u6cbb\u7597\u7684\u5f53\u52a1\u4e4b\u6025\u3002\u201d\u5f90\u745e\u534e\u6559\u6388<\/b>\u8868\u793a\uff0c\u201c\u9488\u5bf9\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\u7684\u5355\u836f\u514d\u75ab\u6cbb\u7597POLARIS-02\u7814\u7a76\u4e3a\u5168\u7403\u9f3b\u54bd\u764c\u6cbb\u7597\u7684\u53d1\u5c55\u8d21\u732e\u4e86\u4e2d\u56fd\u65b9\u6848\u3002\u76ee\u524d\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u5df2\u5411\u7f8e\u56fd\u76d1\u7ba1\u90e8\u95e8\u63d0\u4ea4\u4e86\u4e0a\u5e02\u7533\u8bf7\u3002\u76f8\u4fe1\u518d\u8fc7\u4e0d\u4e45\uff0c\u4e0d\u8bba\u662f\u4e2d\u56fd\u8fd8\u662f\u5168\u7403\u5c42\u9762\uff0c\u9996\u4e2a\u5728\u9f3b\u54bd\u764c\u9886\u57df\u83b7\u6279\u9002\u5e94\u75c7\u7684\u6297PD-1\u5355\u6297\u90fd\u5c06\u662f\u4e2d\u56fd\u2018\u667a\u9020\u2019\u3002\u201d<\/p>\n

\u5728\u9f3b\u54bd\u764c\u6cbb\u7597\u9886\u57df\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u5df2\u5728\u4e34\u5e8a\u5e03\u5c40\u65b9\u9762\u5b9e\u73b0\u4e86\u4ece\u4e00\u7ebf\u81f3\u540e\u7ebf\u7684\u201c\u5168\u7ebf\u8d2f\u7a7f\u201d\uff0c\u5305\u62ec\u8986\u76d6\u540e\u7ebf\u60a3\u8005\u7684POLARIS-02\u7814\u7a76\u548c\u9488\u5bf9\u4e00\u7ebf\u6cbb\u7597\u60a3\u8005\u7684JUPITER-02\uff08NCT03581786\uff09\u7814\u7a76\u3002\u4f1a\u4e0a\uff0c\u4e2d\u5c71\u5927\u5b66\u80bf\u7624\u9632\u6cbb\u4e2d\u5fc3\u9ea6\u6d77\u5f3a\u6559\u6388<\/b>\u4ecb\u7ecd\u4e86\u8fd9\u4e24\u9879\u7814\u7a76\u6240\u53d6\u5f97\u7684\u8fdb\u5c55\u3002<\/p>\n

\u201c\u7279\u745e\u666e\u5229\u5355\u6297\u7684\u65b0\u9002\u5e94\u75c7\u83b7\u6279\u5f00\u521b\u4e86\u4e2d\u56fd\u4e43\u81f3\u5168\u7403\u9f3b\u54bd\u764c\u514d\u75ab\u6cbb\u7597\u7684\u65b0\u7eaa\u5143\u3002\u201d\u9ea6\u6d77\u5f3a\u6559\u6388<\/b>\u8868\u793a\uff0c\u201cPOLARIS-02\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u4e3a\u63a5\u53d7\u8fc7\u4e00\u7ebf\u3001\u4e8c\u7ebf\uff0c\u751a\u81f3\u4e09\u7ebf\u6cbb\u7597\u7684\u60a3\u8005\u5e26\u6765\u4e86\u66f4\u957f\u751f\u5b58\u83b7\u76ca\u3002\u8fd9\u90e8\u5206\u60a3\u8005\u957f\u671f\u4ee5\u6765\u90fd\u5904\u4e8e\u7f3a\u4e4f\u6709\u6548\u836f\u7269\u6cbb\u7597\u7684\u5883\u5730\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u4e3a\u4ed6\u4eec\u5e26\u6765\u4e86\u65b0\u7684\u5e0c\u671b\u3002\u201d<\/p>\n

\u5728POLARIS<\/span>-02\u7814\u7a76\u768492\u4f8b\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e8c\u7ebf\u7cfb\u7edf\u5316\u7597\u5931\u8d25\u7684\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\u4e2d\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u5355\u836f\u6cbb\u7597\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u4e3a23.9%\uff0c\u4e2d\u4f4d\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff08mDOR\uff09\u8fbe\u523014.9\u4e2a\u6708\uff0c\u75be\u75c5\u63a7\u5236\u7387\uff08DCR\uff09\u4e3a41.3%\uff0c\u4e2d\u4f4d\u603b\u751f\u5b58\u65f6\u95f4\uff08mOS\uff09\u8fbe\u523015.1\u4e2a\u6708[1]<\/sup>\u3002<\/p>\n

\u6b64\u5916\uff0c\u5728\u4e00\u7ebf\u6cbb\u7597\u9886\u57df\uff0c\u540c\u6837\u7531\u5f90\u745e\u534e\u6559\u6388\u62c5\u4efb\u4e3b\u8981\u7814\u7a76\u8005\u7684JUPITER-02\u7814\u7a76\u4e5f\u5df2\u8fbe\u5230\u4e3b\u8981\u7814\u7a76\u7ec8\u70b9\u3002JUPITER-02\u7814\u7a76\u662f\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u56fd\u9645\u591a\u4e2d\u5fc3\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u4e5f\u662f\u8fc4\u4eca\u4e3a\u6b62\u5168\u7403\u8303\u56f4\u5185\u89c4\u6a21\u6700\u5927<\/b>\u7684\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\u3002\u6839\u636e\u671f\u4e2d\u5206\u6790\u7ed3\u679c\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5409\u897f\u4ed6\u6ee8\/\u987a\u94c2\u4e00\u7ebf\u6cbb\u7597\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\uff0c\u8f83\u5409\u897f\u4ed6\u6ee8\/\u987a\u94c2\u7684\u6807\u51c6\u4e00\u7ebf\u6cbb\u7597\uff0c\u53ef\u663e\u8457\u5ef6\u957f\u60a3\u8005\u7684\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u3002\u57fa\u4e8eJUPITER-02\u7814\u7a76\uff0c\u541b\u5b9e\u751f\u7269\u4e8e\u4eca\u5e742\u6708\u5411\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u63d0\u4ea4\u4e86\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7528\u4e8e\u665a\u671f\u4e00\u7ebf\u672a\u63a5\u53d7\u8fc7\u7cfb\u7edf\u6027\u6cbb\u7597\u7684\u590d\u53d1\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u5e76\u83b7\u53d7\u7406\u3002<\/p>\n

\u9ea6\u6d77\u5f3a\u6559\u6388<\/b>\u8868\u793a\uff0c\u201c\u7279\u745e\u666e\u5229\u5355\u6297\u4f5c\u4e3a\u4e2d\u56fd\u521b\u65b0\u578b\u836f\u4f01\u751f\u4ea7\u7684\u836f\u7269\uff0c\u5f15\u9886\u56fd\u9645\u6cbb\u7597\u65b9\u6848\uff0c\u901a\u8fc7\u5168\u7403\u591a\u4e2d\u5fc3\u4e34\u5e8a\u7814\u7a76\u5b9a\u4e49\u5168\u65b0\u7684\u9f3b\u54bd\u764c\u6cbb\u7597\u65b9\u6cd5\uff0c\u4e3a\u9f3b\u54bd\u764c\u514d\u75ab\u4e00\u7ebf\u6cbb\u7597\u505a\u51fa\u4e86\u7a81\u51fa\u8d21\u732e\u3002\u201d<\/p>\n

\u541b\u5b9e\u751f\u7269\u9996\u5e2d\u8fd0\u8425\u5b98\u51af\u8f89\u535a\u58eb<\/b>\u5728\u4f1a\u4e0a\u4ecb\u7ecd\u4e86\u541b\u5b9e\u751f\u7269\u7684\u7814\u53d1\u5e03\u5c40\u548c\u672a\u6765\u5c55\u671b\u3002\u201c\u6211\u4eec\u9488\u5bf9\u9f3b\u54bd\u764c\u6cbb\u7597\u5236\u5b9a\u4e86\u2018\u5168\u7ebf\u8d2f\u7a7f\u2019\u7684\u7814\u53d1\u5e03\u5c40\uff0c\u76ee\u524d\u5df2\u83b7\u5f97\u8be5\u9886\u57df\u7684\u4e00\u9879\u9002\u5e94\u75c7\u83b7\u6279\uff0c\u6211\u4eec\u4e5f\u5c06\u7ee7\u7eed\u52aa\u529b\u5411\u524d\u63a8\u8fdb\uff0c\u671f\u5f85\u4e3a\u66f4\u591a\u665a\u671f\u9f3b\u54bd\u764c\u60a3\u8005\u63d0\u4f9b\u66f4\u597d\u7684\u6cbb\u7597\u9009\u62e9\u3002\u201d<\/p>\n

\u51af\u8f89\u535a\u58eb<\/b>\u8868\u793a\uff0c\u4f5c\u4e3a\u541b\u5b9e\u751f\u7269\u80bf\u7624\u514d\u75ab\u9886\u57df\u7684\u6838\u5fc3\u4ea7\u54c1\uff0c\u541b\u5b9e\u751f\u7269\u6b63\u5728\u5168\u7403\u5c42\u9762\u540c\u6b65\u63a8\u8fdb\u7279\u745e\u666e\u5229\u5355\u6297\u7684\u7814\u53d1\u4e0e\u5546\u4e1a\u5316\u5e03\u5c40\uff0c\u6d89\u53ca\u9ed1\u8272\u7d20\u7624\u3001\u9f3b\u54bd\u764c\u3001\u5c3f\u8def\u4e0a\u76ae\u764c\u3001\u80ba\u764c\u3001\u98df\u7ba1\u764c\u3001\u809d\u764c\u3001\u4e73\u817a\u764c\u7b49\u5341\u591a\u4e2a\u7624\u79cd\u300130\u591a\u9879\u5355\u836f\u548c\u8054\u5408\u7597\u6cd5\u7814\u7a76\u3002\u7279\u745e\u666e\u5229\u5355\u6297\u5728\u7f8e\u56fd\u83b7\u5f97FDA\u6388\u4e88\u7684\u7a81\u7834\u6027\u7597\u6cd5\u3001\u5feb\u901f\u901a\u9053\u4ee5\u53ca\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff0c\u4e5f\u5c06\u52a0\u901f\u541b\u5b9e\u751f\u7269\u7684\u6d77\u5916\u5546\u4e1a\u5316\u8fdb\u7a0b\u3002\u51af\u8f89\u535a\u58eb\u8868\u793a\uff0c\u201c\u672a\u6765\uff0c\u541b\u5b9e\u751f\u7269\u5c06\u7ee7\u7eed\u9075\u5faa\u2018\u7acb\u8db3\u672c\u571f\uff0c\u5e03\u5c40\u5168\u7403\u2019\u7684\u6218\u7565\u89c4\u5212\uff0c\u6301\u7eed\u5173\u6ce8\u56fd\u4eba\u4e2d\u9ad8\u53d1\uff0c\u4e14\u5bf9\u514d\u75ab\u6cbb\u7597\u6709\u8f83\u597d\u54cd\u5e94\u3001\u4e34\u5e8a\u6025\u9700\u6cbb\u7597\u7684\u7624\u79cd\uff0c\u4e3a\u4e2d\u56fd\u60a3\u8005\u4e43\u81f3\u5168\u7403\u60a3\u8005\u63d0\u4f9b\u4e16\u754c\u4e00\u6d41\u3001\u503c\u5f97\u4fe1\u8d56\u7684\u751f\u7269\u6e90\u521b\u836f\uff0c\u8d21\u732e\u4e2d\u56fd\u529b\u91cf\u3002\u201d<\/p>\n

\n\n\n\n
\n

[1]<\/sup> \u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca®\uff09\u4ea7\u54c1\u8bf4\u660e\u4e66
<\/b><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n

\u5173\u4e8e<\/b>\u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2<\/b>\uff08<\/b>\u62d3\u76ca<\/b>®<\/sup><\/b>\uff09<\/b><\/p>\n

\u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca®<\/sup>\uff09\u4f5c\u4e3a\u6211\u56fd\u6279\u51c6\u4e0a\u5e02\u7684\u9996\u4e2a\u56fd\u4ea7\u4ee5PD-1\u4e3a\u9776\u70b9\u7684\u5355\u6297\u836f\u7269\uff0c\u83b7\u5f97\u56fd\u5bb6\u79d1\u6280\u91cd\u5927\u4e13\u9879\u9879\u76ee\u652f\u6301\u3002\u672c\u54c1\u83b7\u6279\u7684\u7b2c\u4e00\u4e2a\u9002\u5e94\u75c7\u4e3a\u7528\u4e8e\u65e2\u5f80\u63a5\u53d7\u5168\u8eab\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u7684\u6cbb\u7597\uff0c\u5e76\u83b7\u5f972019\u5e74\u548c2020\u5e74\u7248\u300a\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u9ed1\u8272\u7d20\u7624\u8bca\u7597\u6307\u5357\u300b\u63a8\u8350\u30022020\u5e7412\u6708\uff0c\u62d3\u76ca®<\/sup>\u6210\u529f\u901a\u8fc7\u56fd\u5bb6\u533b\u4fdd\u8c08\u5224\uff0c\u88ab\u7eb3\u5165\u65b0\u7248\u76ee\u5f55\u30022021\u5e742\u6708\uff0c\u62d3\u76ca®<\/sup>\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\uff0c\u7528\u4e8e\u65e2\u5f80\u63a5\u53d7\u8fc7\u4e8c\u7ebf\u53ca\u4ee5\u4e0a\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u7684\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\u7684\u6cbb\u7597\u3002<\/p>\n

2020\u5e745\u6708\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u9002\u7528\u4e8e\u65e2\u5f80\u63a5\u53d7\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u6216\u4e0d\u53ef\u8010\u53d7\u7684\u5c40\u90e8\u8fdb\u5c55\u6216\u8f6c\u79fb\u6027\u5c3f\u8def\u4e0a\u76ae\u764c\u60a3\u8005\u7684\u6cbb\u7597\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40NMPA\u53d7\u7406\uff0c\u5e76\u4e8e2020\u5e747\u6708\u88abNMPA\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u7a0b\u5e8f\u30022020\u5e749\u6708\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u7528\u4e8e\u6cbb\u7597\u9f3b\u54bd\u764c\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u30022021\u5e742\u6708\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7528\u4e8e\u665a\u671f\u4e00\u7ebf\u672a\u63a5\u53d7\u8fc7\u7cfb\u7edf\u6027\u6cbb\u7597\u7684\u590d\u53d1\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97NMPA\u53d7\u7406\u30022021\u5e743\u6708\uff0c\u541b\u5b9e\u751f\u7269\u5f00\u59cb\u5411\u7f8e\u56fdFDA\u6eda\u52a8\u63d0\u4ea4\u7279\u745e\u666e\u5229\u5355\u6297\u4e0a\u5e02\u7533\u8bf7\u3002\u76ee\u524d\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u5df2\u5728\u9ecf\u819c\u9ed1\u8272\u7d20\u7624\u3001\u9f3b\u54bd\u764c\u3001\u8f6f\u7ec4\u7ec7\u8089\u7624\u9886\u57df\u83b7\u5f97FDA\u6388\u4e881\u9879\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u30011\u9879\u5feb\u901f\u901a\u9053\u8ba4\u5b9a\u548c3\u9879\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\u3002<\/p>\n

\u7279\u745e\u666e\u5229\u5355\u6297\u81ea2016\u5e74\u521d\u5f00\u59cb\u4e34\u5e8a\u7814\u53d1\uff0c\u81f3\u4eca\u5df2\u5728\u5168\u7403\u5f00\u5c55\u4e8630\u591a\u9879\u4e34\u5e8a\u7814\u7a76\uff0c\u79ef\u6781\u63a2\u7d22\u672c\u54c1\u5728\u9ed1\u8272\u7d20\u7624\u3001\u9f3b\u54bd\u764c\u3001\u5c3f\u8def\u4e0a\u76ae\u764c\u3001\u80ba\u764c\u3001\u80c3\u764c\u3001\u98df\u7ba1\u764c\u3001\u809d\u764c\u3001\u80c6\u7ba1\u764c\u3001\u4e73\u817a\u764c\u3001\u80be\u764c\u7b49\u9002\u5e94\u75c7\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\uff0c\u4e0e\u56fd\u5185\u5916\u9886\u5148\u521b\u65b0\u836f\u4f01\u7684\u8054\u5408\u7597\u6cd5\u5408\u4f5c\u4e5f\u5728\u8fdb\u884c\u5f53\u4e2d\uff0c\u671f\u5f85\u8ba9\u66f4\u591a\u4e2d\u56fd\u4ee5\u53ca\u5176\u5b83\u56fd\u5bb6\u7684\u60a3\u8005\u83b7\u5f97\u56fd\u9645\u5148\u8fdb\u6c34\u5e73\u7684\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u3002<\/p>\n

\u5173\u4e8e\u541b\u5b9e\u751f\u7269<\/b><\/p>\n

\u541b\u5b9e\u751f\u7269\uff081877.HK\uff0c688180.SH\uff09\u6210\u7acb\u4e8e2012\u5e7412\u6708\uff0c\u662f\u4e00\u5bb6\u4ee5\u521b\u65b0\u4e3a\u9a71\u52a8\uff0c\u81f4\u529b\u4e8e\u521b\u65b0\u7597\u6cd5\u7684\u53d1\u73b0\u3001\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\u3002\u516c\u53f8\u5177\u6709\u4e30\u5bcc\u7684\u5728\u7814\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u5305\u62ec28\u4e2a\u521b\u65b0\u836f\uff0c2\u4e2a\u751f\u7269\u7c7b\u4f3c\u7269\uff0c\u8986\u76d6\u4e94\u5927\u6cbb\u7597\u9886\u57df\uff0c\u5305\u62ec\u6076\u6027\u80bf\u7624\u3001\u81ea\u8eab\u514d\u75ab\u7cfb\u7edf\u75be\u75c5\u3001\u6162\u6027\u4ee3\u8c22\u7c7b\u75be\u75c5\u3001\u795e\u7ecf\u7cfb\u7edf\u7c7b\u75be\u75c5\u4ee5\u53ca\u611f\u67d3\u6027\u75be\u75c5\u3002<\/p>\n

\u51ed\u501f\u86cb\u767d\u8d28\u5de5\u7a0b\u6838\u5fc3\u5e73\u53f0\u6280\u672f\uff0c\u541b\u5b9e\u751f\u7269\u8eab\u5904\u56fd\u9645\u5927\u5206\u5b50\u836f\u7269\u7814\u53d1\u524d\u6cbf\uff0c\u83b7\u5f97\u4e86\u9996\u4e2a\u56fd\u4ea7\u6297PD-1\u5355\u514b\u9686\u6297\u4f53NMPA\u4e0a\u5e02\u6279\u51c6\u3001\u56fd\u4ea7\u6297PCSK9\u5355\u514b\u9686\u6297\u4f53NMPA\u4e34\u5e8a\u7533\u8bf7\u6279\u51c6\u3001\u5168\u7403\u9996\u4e2a\u6cbb\u7597\u80bf\u7624\u6297BTLA\u963b\u65ad\u6297\u4f53\u5728\u4e2d\u56fdNMPA\u548c\u7f8e\u56fdFDA\u7684\u4e34\u5e8a\u7533\u8bf7\u6279\u51c6\uff0c\u5728\u4e2d\u7f8e\u4e24\u5730\u8fdb\u884cI\u671f\u4e34\u5e8a\u7814\u7a76\u30022020\u5e74\uff0c\u541b\u5b9e\u751f\u7269\u8fd8\u4e0e\u56fd\u5185\u79d1\u7814\u673a\u6784\u643a\u624b\u6297\u75ab\uff0c\u5171\u540c\u5f00\u53d1\u7684JS016\u5df2\u4f5c\u4e3a\u56fd\u5185\u9996\u4e2a\u6297\u65b0\u51a0\u75c5\u6bd2\u5355\u514b\u9686\u4e2d\u548c\u6297\u4f53\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u76ee\u524d\u5df2\u5728\u7f8e\u56fd\u3001\u610f\u5927\u5229\u83b7\u5f97\u7d27\u6025\u4f7f\u7528\u6388\u6743\uff0c\u7528\u672c\u571f\u521b\u65b0\u4e3a\u4e2d\u56fd\u548c\u4e16\u754c\u75be\u75c5\u9884\u9632\u63a7\u5236\u8d21\u732e\u529b\u91cf\u3002\u76ee\u524d\u541b\u5b9e\u751f\u7269\u5728\u5168\u7403\u62e5\u6709\u4e24\u5343\u591a\u540d\u5458\u5de5\uff0c\u5206\u5e03\u5728\u7f8e\u56fd\u65e7\u91d1\u5c71\u548c\u9a6c\u91cc\u5170\uff0c\u4e2d\u56fd\u4e0a\u6d77\u3001\u82cf\u5dde\u3001\u5317\u4eac\u548c\u5e7f\u5dde\u3002<\/p>\n

\u76f8\u5173\u94fe\u63a5 :<\/p>\n

http:\/\/www.junshipharma.com<\/p>\n","protected":false},"excerpt":{"rendered":"

\u201c\u65e0\u4e0e\u4f26\u6bd4 \u62d3\u65b0\u60a6\u76ca\u201d \u76f8\u5173\u9002\u5e94\u75c7\u5df2\u540c\u6b65\u5728\u7f8e\u56fd\u63d0\u4ea4\u4e0a\u5e02\u7533\u8bf7 \u4e0a\u6d772021\u5e743\u670822\u65e5 \/\u7f8e\u901a\u793e\/ — 2021\u5e743\u670820\u65e5\uff0c\u4f5c\u4e3a\u201c\u541bDREAM·\u6b63\u5f53\u5b9e\u201d\u7b2c\u4e8c\u5c4aCSCO-\u541b\u5b9e\u751f\u7269\u80bf\u7624\u514d\u75ab\u9ad8\u5cf0\u8bba\u575b\u7684\u91cd\u8981\u73af\u8282 — \u62d3\u76ca®\u9f3b\u54bd\u764c\u9002\u5e94\u75c7\u5168\u56fd\u4e0a\u5e02\u4f1a\u5728\u5e7f\u5dde\u987a\u5229\u53ec\u5f00\u3002\u4e2d\u5c71\u5927\u5b66\u80bf\u7624\u9632\u6cbb\u4e2d\u5fc3\u5f90\u745e\u534e\u6559\u6388\u548c\u5362\u6cf0\u7965\u6559\u6388\u3001\u798f\u5efa\u7701\u80bf\u7624\u533b\u9662\u6f58\u5efa\u57fa\u6559\u6388\u62c5\u4efb\u5927\u4f1a\u540d\u8a89\u4e3b\u5e2d\uff0c\u56fd\u5185\u767e\u4f59\u4f4d\u9f3b\u54bd\u764c\u3001\u5934\u9888\u90e8\u80bf\u7624\u9886\u57df\u4e13\u5bb6\u3001\u5b66\u8005\u548c\u540c\u9053\u9f50\u805a\u4e00\u5802\uff0c\u63a2\u8ba8\u514d\u75ab\u6cbb\u7597\u7684\u673a\u4f1a\u4e0e\u6311\u6218\uff0c\u540c\u65f6\u5e86\u8d3a\u5168\u7403\u9996\u4e2a\u9f3b\u54bd\u764c\u514d\u75ab\u7597\u6cd5\u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca®\uff09\u65b0\u9002\u5e94\u75c7\u6b63\u5f0f\u5728\u5168\u56fd\u4e0a\u5e02\u3002 \u56fd\u5185\u767e\u4f59\u4f4d\u9f3b\u54bd\u764c\u3001\u5934\u9888\u90e8\u80bf\u7624\u9886\u57df\u4e13\u5bb6\u3001\u5b66\u8005\u548c\u540c\u9053\u9f50\u805a\u4e00\u5802\uff0c\u63a2\u8ba8\u514d\u75ab\u6cbb\u7597\u7684\u673a\u4f1a\u4e0e\u6311\u6218\uff0c\u540c\u65f6\u5e86\u8d3a\u5168\u7403\u9996\u4e2a\u9f3b\u54bd\u764c\u514d\u75ab\u7597\u6cd5\u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca(R)\uff09\u65b0\u9002\u5e94\u75c7\u6b63\u5f0f\u5728\u5168\u56fd\u4e0a\u5e02 \u7279\u745e\u666e\u5229\u5355\u6297\u7531\u541b\u5b9e\u751f\u7269\u81ea\u4e3b\u7814\u53d1\uff0c\u662f\u4e00\u6b3e\u91cd\u7ec4\u4eba\u6e90\u5316\u6297PD-1\u5355\u514b\u9686\u6297\u4f53\u6ce8\u5c04\u6db2\uff0c\u81ea\u9762\u4e16\u4ee5\u6765\u5c31\u4e0d\u65ad\u5237\u65b0\u7740\u201c\u7b2c\u4e00\u201d\u30022018\u5e7412\u6708\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u4f5c\u4e3a\u6211\u56fd\u9996\u4e2a\u56fd\u4ea7\u6297PD-1\u5355\u6297\u836f\u7269\u83b7\u6279\u4e0a\u5e02\uff0c\u7528\u4e8e\u65e2\u5f80\u63a5\u53d7\u5168\u8eab\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u7684\u6cbb\u7597\u30022021\u5e742\u6708\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u201c\u518d\u4e0b\u4e00\u57ce\u201d\uff0c\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\uff0c\u7528\u4e8e\u65e2\u5f80\u63a5\u53d7\u8fc7\u4e8c\u7ebf\u53ca\u4ee5\u4e0a\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u7684\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\u7684\u6cbb\u7597\uff0c\u6210\u4e3a\u5168\u7403\u9996\u4e2a\u83b7\u6279\u9f3b\u54bd\u764c\u6cbb\u7597\u7684\u6297PD-1\u5355\u6297\u836f\u7269\uff0c\u5b9e\u73b0\u4e86\u8be5\u9886\u57df\u5185\u514d\u75ab\u6cbb\u7597\u96f6\u7684\u7a81\u7834\u3002\u7d27\u63a5\u77402021\u5e743\u6708\uff0c\u541b\u5b9e\u751f\u7269\u53c8\u518d\u63a5\u518d\u5389\uff0c\u5411\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6eda\u52a8\u63d0\u4ea4\u4e86\u7279\u745e\u666e\u5229\u5355\u6297\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7\u3002\u7279\u745e\u666e\u5229\u5355\u6297\u6210\u4e3a\u9996\u4e2a\u5411\u7f8e\u56fdFDA\u63d0\u4ea4\u4e0a\u5e02\u7533\u8bf7\u7684\u56fd\u4ea7\u6297PD-1\u5355\u6297\u3002 \u6b64\u6b21\u83b7\u6279\u57fa\u4e8e\u4e00\u9879\u591a\u4e2d\u5fc3\u3001\u5f00\u653e\u6807\u7b7e\u3001II\u671f\u5173\u952e\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76\uff08POLARIS-02\u7814\u7a76\uff0cNCT02915432\uff09\uff0c\u5171\u7eb3\u5165190\u4f8b\u65e2\u5f80\u63a5\u53d7\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u7684\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\uff0c\u662f\u8fc4\u4eca\u4e3a\u6b62\u5168\u7403\u8303\u56f4\u5185\u5df2\u5b8c\u6210\u7684\u6700\u5927\u89c4\u6a21\u7684\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u5355\u836f\u6cbb\u7597\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684\u4e34\u5e8a\u8bd5\u9a8c\u3002POLARIS-02\u7814\u7a76\u6210\u679c\u66fe\u9891\u9891\u4eae\u76f8\u56fd\u9645\u5b66\u672f\u821e\u53f0\uff0c\u5148\u540e\u5165\u9009\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\uff08ESMO\uff09\u5e74\u4f1a\u3001\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\uff0c\u5e76\u6700\u7ec8\u6536\u5f55\u5728\u300a\u4e34\u5e8a\u80bf\u7624\u5b66\u6742\u5fd7\u300b\uff08Journal of Clinical Oncology\uff0cIF: 32.956\uff09\u3002\u7279\u745e\u666e\u5229\u5355\u6297\u8fd8\u51ed\u501f\u8fd9\u9879\u7814\u7a76\u83b7\u5f97\u4e86\u7f8e\u56fdFDA\u6388\u4e88\u7684\u5b64\u513f\u836f\u8d44\u683c\u548c\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u8fd9\u4e5f\u662f\u4e2d\u56fd\u6297\u4f53\u7c7b\u836f\u7269\u7b2c\u4e00\u6b21\u83b7\u5f97FDA\u7684\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u3002 POLARIS-02\u7684\u4e3b\u8981\u7814\u7a76\u8005\u4e2d\u5c71\u5927\u5b66\u80bf\u7624\u9632\u6cbb\u4e2d\u5fc3\u9662\u957f\u5f90\u745e\u534e\u6559\u6388\u5728\u5927\u4f1a\u81f4\u8f9e\u4e2d\u5bf9\u7279\u745e\u666e\u5229\u5355\u6297\u65b0\u9002\u5e94\u75c7\u7684\u4e0a\u5e02\u8868\u793a\u795d\u8d3a\uff0c\u5145\u5206\u80af\u5b9a\u4e86\u6211\u56fd\u7814\u53d1\u4eba\u5458\u3001\u7814\u7a76\u8005\u548c\u60a3\u8005\u4e3a\u5168\u7403\u9f3b\u54bd\u764c\u6cbb\u7597\u7684\u53d1\u5c55\u505a\u51fa\u7684\u8d21\u732e\u3002 \u201c\u4e2d\u56fd\u662f\u5168\u7403\u9f3b\u54bd\u764c\u60a3\u8005\u6700\u591a\u7684\u56fd\u5bb6\uff0c\u867d\u7136\u65e9\u671f\u9f3b\u54bd\u764c\u6cbb\u7597\u6548\u679c\u5c1a\u53ef\uff0c\u4f46\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684\u6574\u4f53\u4e34\u5e8a\u9884\u540e\u4e0d\u4f73\uff0c\u56e0\u6b64\u5bfb\u6c42\u66f4\u597d\u7684\u6cbb\u7597\u624b\u6bb5\u662f\u665a\u671f\u9f3b\u54bd\u764c\u6cbb\u7597\u7684\u5f53\u52a1\u4e4b\u6025\u3002\u201d\u5f90\u745e\u534e\u6559\u6388\u8868\u793a\uff0c\u201c\u9488\u5bf9\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\u7684\u5355\u836f\u514d\u75ab\u6cbb\u7597POLARIS-02\u7814\u7a76\u4e3a\u5168\u7403\u9f3b\u54bd\u764c\u6cbb\u7597\u7684\u53d1\u5c55\u8d21\u732e\u4e86\u4e2d\u56fd\u65b9\u6848\u3002\u76ee\u524d\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u5df2\u5411\u7f8e\u56fd\u76d1\u7ba1\u90e8\u95e8\u63d0\u4ea4\u4e86\u4e0a\u5e02\u7533\u8bf7\u3002\u76f8\u4fe1\u518d\u8fc7\u4e0d\u4e45\uff0c\u4e0d\u8bba\u662f\u4e2d\u56fd\u8fd8\u662f\u5168\u7403\u5c42\u9762\uff0c\u9996\u4e2a\u5728\u9f3b\u54bd\u764c\u9886\u57df\u83b7\u6279\u9002\u5e94\u75c7\u7684\u6297PD-1\u5355\u6297\u90fd\u5c06\u662f\u4e2d\u56fd\u2018\u667a\u9020\u2019\u3002\u201d \u5728\u9f3b\u54bd\u764c\u6cbb\u7597\u9886\u57df\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u5df2\u5728\u4e34\u5e8a\u5e03\u5c40\u65b9\u9762\u5b9e\u73b0\u4e86\u4ece\u4e00\u7ebf\u81f3\u540e\u7ebf\u7684\u201c\u5168\u7ebf\u8d2f\u7a7f\u201d\uff0c\u5305\u62ec\u8986\u76d6\u540e\u7ebf\u60a3\u8005\u7684POLARIS-02\u7814\u7a76\u548c\u9488\u5bf9\u4e00\u7ebf\u6cbb\u7597\u60a3\u8005\u7684JUPITER-02\uff08NCT03581786\uff09\u7814\u7a76\u3002\u4f1a\u4e0a\uff0c\u4e2d\u5c71\u5927\u5b66\u80bf\u7624\u9632\u6cbb\u4e2d\u5fc3\u9ea6\u6d77\u5f3a\u6559\u6388\u4ecb\u7ecd\u4e86\u8fd9\u4e24\u9879\u7814\u7a76\u6240\u53d6\u5f97\u7684\u8fdb\u5c55\u3002 \u201c\u7279\u745e\u666e\u5229\u5355\u6297\u7684\u65b0\u9002\u5e94\u75c7\u83b7\u6279\u5f00\u521b\u4e86\u4e2d\u56fd\u4e43\u81f3\u5168\u7403\u9f3b\u54bd\u764c\u514d\u75ab\u6cbb\u7597\u7684\u65b0\u7eaa\u5143\u3002\u201d\u9ea6\u6d77\u5f3a\u6559\u6388\u8868\u793a\uff0c\u201cPOLARIS-02\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u4e3a\u63a5\u53d7\u8fc7\u4e00\u7ebf\u3001\u4e8c\u7ebf\uff0c\u751a\u81f3\u4e09\u7ebf\u6cbb\u7597\u7684\u60a3\u8005\u5e26\u6765\u4e86\u66f4\u957f\u751f\u5b58\u83b7\u76ca\u3002\u8fd9\u90e8\u5206\u60a3\u8005\u957f\u671f\u4ee5\u6765\u90fd\u5904\u4e8e\u7f3a\u4e4f\u6709\u6548\u836f\u7269\u6cbb\u7597\u7684\u5883\u5730\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u4e3a\u4ed6\u4eec\u5e26\u6765\u4e86\u65b0\u7684\u5e0c\u671b\u3002\u201d \u5728POLARIS-02\u7814\u7a76\u768492\u4f8b\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e8c\u7ebf\u7cfb\u7edf\u5316\u7597\u5931\u8d25\u7684\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\u4e2d\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u5355\u836f\u6cbb\u7597\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u4e3a23.9%\uff0c\u4e2d\u4f4d\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff08mDOR\uff09\u8fbe\u523014.9\u4e2a\u6708\uff0c\u75be\u75c5\u63a7\u5236\u7387\uff08DCR\uff09\u4e3a41.3%\uff0c\u4e2d\u4f4d\u603b\u751f\u5b58\u65f6\u95f4\uff08mOS\uff09\u8fbe\u523015.1\u4e2a\u6708[1]\u3002 \u6b64\u5916\uff0c\u5728\u4e00\u7ebf\u6cbb\u7597\u9886\u57df\uff0c\u540c\u6837\u7531\u5f90\u745e\u534e\u6559\u6388\u62c5\u4efb\u4e3b\u8981\u7814\u7a76\u8005\u7684JUPITER-02\u7814\u7a76\u4e5f\u5df2\u8fbe\u5230\u4e3b\u8981\u7814\u7a76\u7ec8\u70b9\u3002JUPITER-02\u7814\u7a76\u662f\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u56fd\u9645\u591a\u4e2d\u5fc3\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u4e5f\u662f\u8fc4\u4eca\u4e3a\u6b62\u5168\u7403\u8303\u56f4\u5185\u89c4\u6a21\u6700\u5927\u7684\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\u3002\u6839\u636e\u671f\u4e2d\u5206\u6790\u7ed3\u679c\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5409\u897f\u4ed6\u6ee8\/\u987a\u94c2\u4e00\u7ebf\u6cbb\u7597\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\uff0c\u8f83\u5409\u897f\u4ed6\u6ee8\/\u987a\u94c2\u7684\u6807\u51c6\u4e00\u7ebf\u6cbb\u7597\uff0c\u53ef\u663e\u8457\u5ef6\u957f\u60a3\u8005\u7684\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u3002\u57fa\u4e8eJUPITER-02\u7814\u7a76\uff0c\u541b\u5b9e\u751f\u7269\u4e8e\u4eca\u5e742\u6708\u5411\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u63d0\u4ea4\u4e86\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7528\u4e8e\u665a\u671f\u4e00\u7ebf\u672a\u63a5\u53d7\u8fc7\u7cfb\u7edf\u6027\u6cbb\u7597\u7684\u590d\u53d1\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u5e76\u83b7\u53d7\u7406\u3002 \u9ea6\u6d77\u5f3a\u6559\u6388\u8868\u793a\uff0c\u201c\u7279\u745e\u666e\u5229\u5355\u6297\u4f5c\u4e3a\u4e2d\u56fd\u521b\u65b0\u578b\u836f\u4f01\u751f\u4ea7\u7684\u836f\u7269\uff0c\u5f15\u9886\u56fd\u9645\u6cbb\u7597\u65b9\u6848\uff0c\u901a\u8fc7\u5168\u7403\u591a\u4e2d\u5fc3\u4e34\u5e8a\u7814\u7a76\u5b9a\u4e49\u5168\u65b0\u7684\u9f3b\u54bd\u764c\u6cbb\u7597\u65b9\u6cd5\uff0c\u4e3a\u9f3b\u54bd\u764c\u514d\u75ab\u4e00\u7ebf\u6cbb\u7597\u505a\u51fa\u4e86\u7a81\u51fa\u8d21\u732e\u3002\u201d \u541b\u5b9e\u751f\u7269\u9996\u5e2d\u8fd0\u8425\u5b98\u51af\u8f89\u535a\u58eb\u5728\u4f1a\u4e0a\u4ecb\u7ecd\u4e86\u541b\u5b9e\u751f\u7269\u7684\u7814\u53d1\u5e03\u5c40\u548c\u672a\u6765\u5c55\u671b\u3002\u201c\u6211\u4eec\u9488\u5bf9\u9f3b\u54bd\u764c\u6cbb\u7597\u5236\u5b9a\u4e86\u2018\u5168\u7ebf\u8d2f\u7a7f\u2019\u7684\u7814\u53d1\u5e03\u5c40\uff0c\u76ee\u524d\u5df2\u83b7\u5f97\u8be5\u9886\u57df\u7684\u4e00\u9879\u9002\u5e94\u75c7\u83b7\u6279\uff0c\u6211\u4eec\u4e5f\u5c06\u7ee7\u7eed\u52aa\u529b\u5411\u524d\u63a8\u8fdb\uff0c\u671f\u5f85\u4e3a\u66f4\u591a\u665a\u671f\u9f3b\u54bd\u764c\u60a3\u8005\u63d0\u4f9b\u66f4\u597d\u7684\u6cbb\u7597\u9009\u62e9\u3002\u201d \u51af\u8f89\u535a\u58eb\u8868\u793a\uff0c\u4f5c\u4e3a\u541b\u5b9e\u751f\u7269\u80bf\u7624\u514d\u75ab\u9886\u57df\u7684\u6838\u5fc3\u4ea7\u54c1\uff0c\u541b\u5b9e\u751f\u7269\u6b63\u5728\u5168\u7403\u5c42\u9762\u540c\u6b65\u63a8\u8fdb\u7279\u745e\u666e\u5229\u5355\u6297\u7684\u7814\u53d1\u4e0e\u5546\u4e1a\u5316\u5e03\u5c40\uff0c\u6d89\u53ca\u9ed1\u8272\u7d20\u7624\u3001\u9f3b\u54bd\u764c\u3001\u5c3f\u8def\u4e0a\u76ae\u764c\u3001\u80ba\u764c\u3001\u98df\u7ba1\u764c\u3001\u809d\u764c\u3001\u4e73\u817a\u764c\u7b49\u5341\u591a\u4e2a\u7624\u79cd\u300130\u591a\u9879\u5355\u836f\u548c\u8054\u5408\u7597\u6cd5\u7814\u7a76\u3002\u7279\u745e\u666e\u5229\u5355\u6297\u5728\u7f8e\u56fd\u83b7\u5f97FDA\u6388\u4e88\u7684\u7a81\u7834\u6027\u7597\u6cd5\u3001\u5feb\u901f\u901a\u9053\u4ee5\u53ca\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff0c\u4e5f\u5c06\u52a0\u901f\u541b\u5b9e\u751f\u7269\u7684\u6d77\u5916\u5546\u4e1a\u5316\u8fdb\u7a0b\u3002\u51af\u8f89\u535a\u58eb\u8868\u793a\uff0c\u201c\u672a\u6765\uff0c\u541b\u5b9e\u751f\u7269\u5c06\u7ee7\u7eed\u9075\u5faa\u2018\u7acb\u8db3\u672c\u571f\uff0c\u5e03\u5c40\u5168\u7403\u2019\u7684\u6218\u7565\u89c4\u5212\uff0c\u6301\u7eed\u5173\u6ce8\u56fd\u4eba\u4e2d\u9ad8\u53d1\uff0c\u4e14\u5bf9\u514d\u75ab\u6cbb\u7597\u6709\u8f83\u597d\u54cd\u5e94\u3001\u4e34\u5e8a\u6025\u9700\u6cbb\u7597\u7684\u7624\u79cd\uff0c\u4e3a\u4e2d\u56fd\u60a3\u8005\u4e43\u81f3\u5168\u7403\u60a3\u8005\u63d0\u4f9b\u4e16\u754c\u4e00\u6d41\u3001\u503c\u5f97\u4fe1\u8d56\u7684\u751f\u7269\u6e90\u521b\u836f\uff0c\u8d21\u732e\u4e2d\u56fd\u529b\u91cf\u3002\u201d [1] \u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca®\uff09\u4ea7\u54c1\u8bf4\u660e\u4e66 \u5173\u4e8e\u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca®\uff09 \u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u62d3\u76ca®\uff09\u4f5c\u4e3a\u6211\u56fd\u6279\u51c6\u4e0a\u5e02\u7684\u9996\u4e2a\u56fd\u4ea7\u4ee5PD-1\u4e3a\u9776\u70b9\u7684\u5355\u6297\u836f\u7269\uff0c\u83b7\u5f97\u56fd\u5bb6\u79d1\u6280\u91cd\u5927\u4e13\u9879\u9879\u76ee\u652f\u6301\u3002\u672c\u54c1\u83b7\u6279\u7684\u7b2c\u4e00\u4e2a\u9002\u5e94\u75c7\u4e3a\u7528\u4e8e\u65e2\u5f80\u63a5\u53d7\u5168\u8eab\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u7684\u6cbb\u7597\uff0c\u5e76\u83b7\u5f972019\u5e74\u548c2020\u5e74\u7248\u300a\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u9ed1\u8272\u7d20\u7624\u8bca\u7597\u6307\u5357\u300b\u63a8\u8350\u30022020\u5e7412\u6708\uff0c\u62d3\u76ca®\u6210\u529f\u901a\u8fc7\u56fd\u5bb6\u533b\u4fdd\u8c08\u5224\uff0c\u88ab\u7eb3\u5165\u65b0\u7248\u76ee\u5f55\u30022021\u5e742\u6708\uff0c\u62d3\u76ca®\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\uff0c\u7528\u4e8e\u65e2\u5f80\u63a5\u53d7\u8fc7\u4e8c\u7ebf\u53ca\u4ee5\u4e0a\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u7684\u590d\u53d1\/\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u60a3\u8005\u7684\u6cbb\u7597\u3002 2020\u5e745\u6708\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u9002\u7528\u4e8e\u65e2\u5f80\u63a5\u53d7\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u6216\u4e0d\u53ef\u8010\u53d7\u7684\u5c40\u90e8\u8fdb\u5c55\u6216\u8f6c\u79fb\u6027\u5c3f\u8def\u4e0a\u76ae\u764c\u60a3\u8005\u7684\u6cbb\u7597\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40NMPA\u53d7\u7406\uff0c\u5e76\u4e8e2020\u5e747\u6708\u88abNMPA\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u7a0b\u5e8f\u30022020\u5e749\u6708\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u7528\u4e8e\u6cbb\u7597\u9f3b\u54bd\u764c\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u30022021\u5e742\u6708\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u8054\u5408\u5316\u7597\u7528\u4e8e\u665a\u671f\u4e00\u7ebf\u672a\u63a5\u53d7\u8fc7\u7cfb\u7edf\u6027\u6cbb\u7597\u7684\u590d\u53d1\u8f6c\u79fb\u6027\u9f3b\u54bd\u764c\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97NMPA\u53d7\u7406\u30022021\u5e743\u6708\uff0c\u541b\u5b9e\u751f\u7269\u5f00\u59cb\u5411\u7f8e\u56fdFDA\u6eda\u52a8\u63d0\u4ea4\u7279\u745e\u666e\u5229\u5355\u6297\u4e0a\u5e02\u7533\u8bf7\u3002\u76ee\u524d\uff0c\u7279\u745e\u666e\u5229\u5355\u6297\u5df2\u5728\u9ecf\u819c\u9ed1\u8272\u7d20\u7624\u3001\u9f3b\u54bd\u764c\u3001\u8f6f\u7ec4\u7ec7\u8089\u7624\u9886\u57df\u83b7\u5f97FDA\u6388\u4e881\u9879\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u30011\u9879\u5feb\u901f\u901a\u9053\u8ba4\u5b9a\u548c3\u9879\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\u3002 \u7279\u745e\u666e\u5229\u5355\u6297\u81ea2016\u5e74\u521d\u5f00\u59cb\u4e34\u5e8a\u7814\u53d1\uff0c\u81f3\u4eca\u5df2\u5728\u5168\u7403\u5f00\u5c55\u4e8630\u591a\u9879\u4e34\u5e8a\u7814\u7a76\uff0c\u79ef\u6781\u63a2\u7d22\u672c\u54c1\u5728\u9ed1\u8272\u7d20\u7624\u3001\u9f3b\u54bd\u764c\u3001\u5c3f\u8def\u4e0a\u76ae\u764c\u3001\u80ba\u764c\u3001\u80c3\u764c\u3001\u98df\u7ba1\u764c\u3001\u809d\u764c\u3001\u80c6\u7ba1\u764c\u3001\u4e73\u817a\u764c\u3001\u80be\u764c\u7b49\u9002\u5e94\u75c7\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\uff0c\u4e0e\u56fd\u5185\u5916\u9886\u5148\u521b\u65b0\u836f\u4f01\u7684\u8054\u5408\u7597\u6cd5\u5408\u4f5c\u4e5f\u5728\u8fdb\u884c\u5f53\u4e2d\uff0c\u671f\u5f85\u8ba9\u66f4\u591a\u4e2d\u56fd\u4ee5\u53ca\u5176\u5b83\u56fd\u5bb6\u7684\u60a3\u8005\u83b7\u5f97\u56fd\u9645\u5148\u8fdb\u6c34\u5e73\u7684\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u3002 \u5173\u4e8e\u541b\u5b9e\u751f\u7269 \u541b\u5b9e\u751f\u7269\uff081877.HK\uff0c688180.SH\uff09\u6210\u7acb\u4e8e2012\u5e7412\u6708\uff0c\u662f\u4e00\u5bb6\u4ee5\u521b\u65b0\u4e3a\u9a71\u52a8\uff0c\u81f4\u529b\u4e8e\u521b\u65b0\u7597\u6cd5\u7684\u53d1\u73b0\u3001\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\u3002\u516c\u53f8\u5177\u6709\u4e30\u5bcc\u7684\u5728\u7814\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u5305\u62ec28\u4e2a\u521b\u65b0\u836f\uff0c2\u4e2a\u751f\u7269\u7c7b\u4f3c\u7269\uff0c\u8986\u76d6\u4e94\u5927\u6cbb\u7597\u9886\u57df\uff0c\u5305\u62ec\u6076\u6027\u80bf\u7624\u3001\u81ea\u8eab\u514d\u75ab\u7cfb\u7edf\u75be\u75c5\u3001\u6162\u6027\u4ee3\u8c22\u7c7b\u75be\u75c5\u3001\u795e\u7ecf\u7cfb\u7edf\u7c7b\u75be\u75c5\u4ee5\u53ca\u611f\u67d3\u6027\u75be\u75c5\u3002 \u51ed\u501f\u86cb\u767d\u8d28\u5de5\u7a0b\u6838\u5fc3\u5e73\u53f0\u6280\u672f\uff0c\u541b\u5b9e\u751f\u7269\u8eab\u5904\u56fd\u9645\u5927\u5206\u5b50\u836f\u7269\u7814\u53d1\u524d\u6cbf\uff0c\u83b7\u5f97\u4e86\u9996\u4e2a\u56fd\u4ea7\u6297PD-1\u5355\u514b\u9686\u6297\u4f53NMPA\u4e0a\u5e02\u6279\u51c6\u3001\u56fd\u4ea7\u6297PCSK9\u5355\u514b\u9686\u6297\u4f53NMPA\u4e34\u5e8a\u7533\u8bf7\u6279\u51c6\u3001\u5168\u7403\u9996\u4e2a\u6cbb\u7597\u80bf\u7624\u6297BTLA\u963b\u65ad\u6297\u4f53\u5728\u4e2d\u56fdNMPA\u548c\u7f8e\u56fdFDA\u7684\u4e34\u5e8a\u7533\u8bf7\u6279\u51c6\uff0c\u5728\u4e2d\u7f8e\u4e24\u5730\u8fdb\u884cI\u671f\u4e34\u5e8a\u7814\u7a76\u30022020\u5e74\uff0c\u541b\u5b9e\u751f\u7269\u8fd8\u4e0e\u56fd\u5185\u79d1\u7814\u673a\u6784\u643a\u624b\u6297\u75ab\uff0c\u5171\u540c\u5f00\u53d1\u7684JS016\u5df2\u4f5c\u4e3a\u56fd\u5185\u9996\u4e2a\u6297\u65b0\u51a0\u75c5\u6bd2\u5355\u514b\u9686\u4e2d\u548c\u6297\u4f53\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u76ee\u524d\u5df2\u5728\u7f8e\u56fd\u3001\u610f\u5927\u5229\u83b7\u5f97\u7d27\u6025\u4f7f\u7528\u6388\u6743\uff0c\u7528\u672c\u571f\u521b\u65b0\u4e3a\u4e2d\u56fd\u548c\u4e16\u754c\u75be\u75c5\u9884\u9632\u63a7\u5236\u8d21\u732e\u529b\u91cf\u3002\u76ee\u524d\u541b\u5b9e\u751f\u7269\u5728\u5168\u7403\u62e5\u6709\u4e24\u5343\u591a\u540d\u5458\u5de5\uff0c\u5206\u5e03\u5728\u7f8e\u56fd\u65e7\u91d1\u5c71\u548c\u9a6c\u91cc\u5170\uff0c\u4e2d\u56fd\u4e0a\u6d77\u3001\u82cf\u5dde\u3001\u5317\u4eac\u548c\u5e7f\u5dde\u3002 \u76f8\u5173\u94fe\u63a5 : http:\/\/www.junshipharma.com… Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":23614,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-23611","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/23611","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=23611"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/23611\/revisions"}],"predecessor-version":[{"id":23613,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/23611\/revisions\/23613"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/23614"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=23611"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=23611"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=23611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}