\u82cf\u5dde2021\u5e742\u670818\u65e5 \/\u7f8e\u901a\u793e\/ — 2021\u5e742\u670818\u65e5\uff0c\u5f00\u62d3\u836f\u4e1a\u6709\u9650\u516c\u53f8\uff08\u80a1\u7968\u4ee3\u7801\uff1a9939.HK\uff0c\u4ee5\u4e0b\u7b80\u79f0\uff1a\u201c\u5f00\u62d3\u836f\u4e1a\u201d\uff09\u5ba3\u5e03\uff0c\u5176ALK-1\u6297\u4f53GT90001\u8054\u5408\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d(BMS)\u7684PD-1\u5355\u6297Nivolumab (Opdivo)\u4e8c\u7ebf\u6cbb\u7597\u665a\u671f\u809d\u7ec6\u80de\u764c(HCC)\u7684II\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff08\u5168\u7403\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\uff0cMRCT\uff09\u7533\u8bf7\u5df2\u83b7\u5f97\u7f8e\u56fdFDA\u7684\u6279\u51c6\u3002<\/p>\n
GT90001\u662f\u4e00\u79cd\u5168\u4eba\u6e90IgG2<\/sub>\u4e2d\u548c\u6297\u4f53\uff0c\u53ef\u6291\u5236ALK-1\/ TGF-\u03b2\u4fe1\u53f7\u8f6c\u5bfc\u548c\u80bf\u7624\u8840\u7ba1\u751f\u6210\u3002GT90001\u8054\u5408Nivolumab\u9488\u5bf9\u4e00\u7ebf\u7d22\u62c9\u975e\u5c3c\u6216\u4ed1\u4f10\u66ff\u5c3c\u6cbb\u7597\u540e\u8fdb\u5c55\u7684\u665a\u671fHCC\u60a3\u8005\u7684II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u9996\u5148\u5728\u4e2d\u56fd\u53f0\u6e7e\u5f00\u5c55\u3002\u6b64\u524d\u5728ASCO GI 2021\u4e0a\u516c\u5e03\u7684\u53f0\u6e7e\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u663e\u793a\uff0c\u8be5\u8054\u5408\u7597\u6cd5\u7684\u7597\u6548\u4ee4\u4eba\u9f13\u821e\u4e14\u5b89\u5168\u6027\u826f\u597d\uff0c\u5176\u4e2d\u5ba2\u89c2\u7f13\u89e3\u7387(ORR)\u8fbe\u523040%\u3002\uff08\u5177\u4f53\u4fe1\u606f\u8be6\u89c1\u65b0\u95fb\u201c\u5f00\u62d3\u836f\u4e1aGT90001\u8054\u5408Nivolumab\u6cbb\u7597\u665a\u671f\u809d\u764cII\u671f\u4e34\u5e8a\u7814\u7a76\u4eae\u76f8ASCO GI 2021<\/a><\/u>\u201d\uff09<\/p>\n 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