{"id":19234,"date":"2021-02-01T07:09:00","date_gmt":"2021-02-01T00:09:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021020107090019234"},"modified":"2021-02-01T09:12:29","modified_gmt":"2021-02-01T01:12:29","slug":"%e4%b8%89%e6%96%b9%e5%90%88%e5%8a%9b%ef%bc%81%e5%be%b7%e7%90%aa%e5%8c%bb%e8%8d%af%e4%b8%8e%e8%8d%af%e6%98%8e%e7%94%9f%e7%89%a9%e3%80%81%e5%90%88%e5%85%a8%e8%8d%af%e4%b8%9a%e5%90%af%e5%8a%a8%e5%90%88","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021020107090019234","title":{"rendered":"\u4e09\u65b9\u5408\u529b\uff01\u5fb7\u742a\u533b\u836f\u4e0e\u836f\u660e\u751f\u7269\u3001\u5408\u5168\u836f\u4e1a\u542f\u52a8\u5408\u4f5c\uff0c\u52a0\u901f\u6297\u4f53\u5076\u8054\u836f\u7269\uff08ADC\uff09\u7814\u53d1\u751f\u4ea7"},"content":{"rendered":"

\u4e0a\u6d77\u548c\u9999\u6e2f2021\u5e742\u67081\u65e5 \/\u7f8e\u901a\u793e\/ — \u81f4\u529b\u4e8e\u7814\u53d1\u548c\u5546\u4e1a\u5316\u521b\u65b0\u80bf\u7624\u7597\u6cd5\u7684\u751f\u7269\u5236\u836f\u516c\u53f8 — \u5fb7\u742a\u533b\u836f\u6709\u9650\u516c\u53f8\uff08\u7b80\u79f0\u201c\u5fb7\u742a\u533b\u836f\u201d\uff0c6996.HK\uff09\u4e0e\u5168\u7403\u9886\u5148\u7684\u5f00\u653e\u5f0f\u751f\u7269\u5236\u836f\u6280\u672f\u5e73\u53f0\u516c\u53f8\u836f\u660e\u751f\u7269\uff08WuXi Biologics, 2269.HK\uff09\u53ca\u5168\u7403\u9886\u5148\u7684\u65b0\u836f\u7814\u53d1\u751f\u4ea7CDMO\u4f01\u4e1a\u5408\u5168\u836f\u4e1a\u4eca\u65e5\u5ba3\u5e03\uff0c\u4e09\u65b9\u8fbe\u6210\u6218\u7565\u5408\u4f5c\uff0c\u5171\u540c\u52a0\u901f\u521b\u65b0\u6297\u4f53\u5076\u8054\u836f\u7269\uff08Antibody-Drug Conjugate, ADC\uff09\u7684\u7814\u53d1\u751f\u4ea7\u3002\u8fd9\u4e5f\u662f\u81ea2020\u5e7410\u6708\u5fb7\u742a\u533b\u836f\u4e0e\u836f\u660e\u751f\u7269\u9488\u5bf9\u53cc\u7279\u5f02\u6027\u6297\u4f53\u8fbe\u6210CDMO\u5408\u4f5c\u540e\uff0c\u53cc\u65b9\u7b2c\u4e8c\u6b21\u5728GMP\u751f\u4ea7\u65b9\u9762\u5efa\u7acb\u5408\u4f5c\u3002\u5fb7\u742a\u533b\u836f\u5c06\u57fa\u4e8e\u81ea\u8eab\u7684\u7814\u53d1\u4f18\u52bf\uff0c\u901a\u8fc7\u201c\u5e73\u53f0+\u81ea\u7814\u201d\u5e76\u884c\u7684\u7b56\u7565\uff0c\u63d0\u9ad8ADC\u836f\u7269\u7b49\u65e9\u671f\u7814\u53d1\u9879\u76ee\u7684\u5b75\u5316\u6548\u7387\u3002<\/p>\n

\u9488\u5bf9\u56fd\u5185\u53ca\u4e9a\u592a\u60a3\u8005\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u5fb7\u742a\u533b\u836f\u81ea\u4e3b\u7814\u53d1\u4e0e\u5408\u4f5c\u5f15\u8fdb\u9f50\u5934\u5e76\u8fdb\uff0c\u5e03\u5c40\u4e86\u5305\u62ecADC\u836f\u7269\u5728\u5185\u76846\u6b3e\u521b\u65b0\u578b\u65e9\u671f\u7814\u53d1\u9879\u76ee\u3002\u5728\u7814\u53d1\u56e2\u961f\u6301\u7eed\u6709\u529b\u5730\u63a8\u8fdb\u4e0b\uff0c\u591a\u6b3e\u65e9\u671f\u836f\u7269\u9646\u7eed\u8fdb\u5165\u7814\u53d1<\/span>\u751f\u4ea7\u9636\u6bb5\u3002ADC\u662f\u4e00\u79cd\u901a\u8fc7\u8fde\u63a5\u5b50\uff08linker<\/span>\uff09\u5c06\u5177\u6709\u80bf\u7624\u7ec6\u80de\u6740\u4f24\u529b\u7684\u5c0f\u5206\u5b50\u836f\u7269\u5076\u8054\u81f3\u5355\u514b\u9686\u6297\u4f53\u4e0a\u800c\u4ea7\u751f\u7684\u590d\u5408\u4f53\u836f\u7269\uff0c\u51ed\u501f\u5176\u9ad8\u7cbe\u51c6\u5ea6\u548c\u663e\u8457\u7684\u6cbb\u7597\u6548\u679c\uff0c\u5df2\u9010\u6e10\u6210\u4e3a\u80bf\u7624\u9776\u5411\u6cbb\u7597\u9886\u57df\u7684\u65b0\u5174\u7597\u6cd5\u3002\u6b64\u6b21\u6218\u7565\u5408\u4f5c\uff0c\u836f\u660e\u751f\u7269\u4e0e\u5408\u5168\u836f\u4e1a\u5c06\u4e3a\u5fb7\u742a\u533b\u836fADC\u836f\u7269\u5f00\u53d1\u63d0\u4f9b\u4ea7\u54c1\u4e2d\u95f4\u4f53\u7684\u89c4\u6a21\u653e\u5927\u3001\u5de5\u827a\u5f00\u53d1\u548cGMP\u751f\u4ea7\u670d\u52a1\u3002\u5176\u4e2d\uff0c\u5fb7\u742a\u533b\u836f\u4e13\u6ce8\u4e8e\u6297\u4f53\u5076\u8054\u836f\u7269\u7684\u6838\u5fc3\u8981\u7d20 — \u5355\u514b\u9686\u6297\u4f53\u7684\u7814\u53d1\uff1b\u5408\u5168\u836f\u4e1a\u4e13\u6ce8\u4e8e\u8fde\u63a5\u4f53\u548c\u6709\u6548\u8f7d\u8377\uff08payload\uff09\u7684GMP\u751f\u4ea7\uff1b\u836f\u660e\u751f\u7269\u4e13\u6ce8\u4e8e\u5355\u514b\u9686\u6297\u4f53\uff08mAb\uff09\uff0c\u751f\u7269\u5076\u8054\u548c\u6210\u54c1\u51bb\u5e72\u5de5\u827a\u5f00\u53d1\uff0c\u5e76\u4ee5GMP\u6807\u51c6\u751f\u4ea7\u5076\u8054\u539f\u6db2\u548c\u51bb\u5e72\u5236\u5242\u3002\u4e09\u65b9\u5c06\u901a\u8fc7\u8d44\u6e90\u5339\u914d\u548c\u6280\u672f\u4e92\u8865\uff0c\u4fc3\u4f7fADC\u836f\u7269\u6982\u5ff5\u843d\u5730\uff0c\u4e3a\u60a3\u8005\u63d0\u4f9b\u884c\u4e4b\u6709\u6548\u7684\u6cbb\u7597\u624b\u6bb5\u3002<\/p>\n

\u5fb7\u742a\u533b\u836f\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u6885\u5efa\u660e\u535a\u58eb\u8868\u793a\uff1a\u201c\u5f88\u9ad8\u5174\u5fb7\u742a\u4e0e\u836f\u660e\u751f\u7269\u3001\u5408\u5168\u836f\u4e1a\u5efa\u7acb\u7684\u9ad8\u6548\u7a33\u5b9a\u7684\u5408\u4f5c\u5173\u7cfb\u3002\u6211\u4eec\u4e00\u76f4\u6ce8\u91cd\u81ea\u4e3b\u7814\u53d1\u4f53\u7cfb\u7684\u642d\u5efa\uff0c\u901a\u8fc7\u5efa\u7acb\u5fb7\u742a\u65b0\u836f\u7814\u53d1\u4e2d\u5fc3\uff0c\u5168\u9762\u5e03\u5c40\u65e9\u671f\u7814\u53d1\u9879\u76ee\uff1b\u6211\u4eec\u7acb\u8db3\u8054\u5408\u4e0e\u4e92\u8865\u7684\u6218\u7565\uff0c\u901a\u8fc7\u4e34\u5e8a\u56e2\u961f\u3001\u6ce8\u518c\u56e2\u961f\u548c\u65e9\u671f\u7814\u53d1\u56e2\u961f\u7684\u6574\u5408\uff0c\u66f4\u9ad8\u6548\u5730\u63a8\u8fdb\u836f\u7269\u7814\u53d1\u9879\u76ee\u3002\u76f8\u4fe1\u5408\u5168\u836f\u4e1a\u53ca\u836f\u660e\u751f\u7269\u5728ADC\u836f\u7269\u9886\u57df\u7684\u6df1\u539a\u79ef\u6dc0\u5c06\u4e0e\u5fb7\u742a\u7684\u521b\u65b0\u7406\u5ff5\u76f8\u7ed3\u5408\uff0c\u5f62\u6210\u66f4\u5f3a\u5927\u7684\u6280\u672f\u5408\u529b\uff0c\u52a0\u901fADC\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u53ca\u5e94\u7528\uff0c\u65e9\u65e5\u9020\u798f\u75c5\u60a3\u3002\u201d<\/p>\n

\u5fb7\u742a\u533b\u836f\u96c6\u56e2\u526f\u603b\u88c1\u3001\u65e9\u671f\u836f\u7269\u7814\u53d1\u53ca\u836f\u7269\u751f\u4ea7\u8d1f\u8d23\u4eba\u5355\u6ce2\u535a\u58eb\u8868\u793a\uff1a\u201c\u76ee\u524d\uff0c\u5fb7\u742a\u65e9\u671f\u7814\u53d1\u7684\u8282\u594f\u4e0d\u65ad\u52a0\u5feb\uff0cADC\u836f\u7269\u6cbb\u7597\u4f18\u52bf\u660e\u663e\uff0c\u9002\u7528\u4eba\u7fa4\u5e7f\u6cdb\uff0c\u62e5\u6709\u5de8\u5927<\/span>\u7684\u5e02\u573a\u6f5c\u529b\u3002\u76f8\u4fe1\u6b64\u6b21\u5408\u4f5c\u540e\uff0c\u5fb7\u742a\u5c06\u4ee5\u66f4\u9ad8\u6807\u51c6\u7684\u751f\u4ea7\u5de5\u827a\u548c\u8d28\u91cf\u4f53\u7cfb\uff0c\u7814\u53d1\u751f\u4ea7\u9ad8\u8d28\u91cf\u7684ADC\u836f\u7269\uff0c\u5728\u5168\u7403\u521b\u65b0\u836f\u7269\u7814\u53d1\u4e0a\u4e0d\u65ad\u63d0\u9ad8\u6838\u5fc3\u7ade\u4e89\u529b<\/span>\u3002\u201d<\/p>\n

\u836f\u660e\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u9648\u667a\u80dc\u535a\u58eb\u8868\u793a\uff1a\u201c\u6211\u4eec\u975e\u5e38\u9ad8\u5174\u4e0e\u5fb7\u742a\u533b\u836f\u6269\u5927\u6218\u7565\u5408\u4f5c\uff0c\u901a\u8fc7\u836f\u660e\u751f\u7269\u5353\u8d8a\u7684\u751f\u7269\u6280\u672f\u5e73\u53f0\u3001\u5145\u8db3\u7684\u4ea7\u80fd\u4ee5\u53ca\u9ad8\u8d28\u91cf\u6807\u51c6\uff0c\u52a0\u901f\u5c06\u5fb7\u742a\u533b\u836f\u521b\u65b0ADC\u836f\u7269\u63a8\u8fdb\u81f3\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002\u836f\u660e\u751f\u7269\u5c06\u6301\u7eed\u5728ADC\u836f\u7269\u9886\u57df\u592f\u5b9e\u80fd\u529b\u548c\u89c4\u6a21\u5efa\u8bbe\uff0c\u8d4b\u80fd\u5168\u7403\u5408\u4f5c\u4f19\u4f34\u62e5\u62b1\u65b0\u4e00\u4ee3\u751f\u7269\u836f\u6d6a\u6f6e\uff0c\u65e9\u65e5\u9020\u798f\u5e7f\u5927\u60a3\u8005\u3002\u201d<\/p>\n

\u5408\u5168\u836f\u4e1a\u9996\u5e2d\u6267\u884c\u5b98\u9648\u6c11\u7ae0\u535a\u58eb\u8868\u793a\uff1a\u201c\u975e\u5e38\u9ad8\u5174\u4e0e\u5fb7\u742a\u533b\u836f\u8fdb\u4e00\u6b65\u6269\u5927\u5408\u4f5c\u7684\u8303\u56f4\u4e0e\u6df1\u5ea6\uff0c\u76f8\u4fe1\u5408\u5168\u836f\u4e1a\u5728\u9ad8\u6d3b\u539f\u6599\u836f\u65b9\u9762\u548c\u6d89\u53caADC\u7b49\u65b0\u578b\u836f\u7269\u5206\u5b50\u7684\u5076\u8054\u5316\u5b66\u65b9\u9762\u7684\u9886\u5148\u80fd\u529b\u548c\u89c4\u6a21\u4f18\u52bf\uff0c\u4ee5\u53ca\u7b26\u5408\u5168\u7403\u6807\u51c6\u7684\u8d28\u91cf\u4f53\u7cfb\uff0c\u5c06\u4e3a\u5fb7\u742a\u533b\u836fADC\u836f\u7269\u9879\u76ee\u63d0\u4f9b\u5f3a\u6709\u529b\u7684\u652f\u6491\u3002\u5408\u5168\u836f\u4e1a\u5c06\u7ee7\u7eed\u63d0\u5347\u65b0\u578b\u836f\u7269\u5206\u5b50\u4ece\u4e34\u5e8a\u524d\u81f3\u5546\u4e1a\u5316\u7684\u4e00\u4f53\u5316CMC\u80fd\u529b\uff0c\u8d4b\u80fd\u66f4\u591a\u5168\u7403\u5408\u4f5c\u4f19\u4f34\uff0c\u60e0\u53ca\u66f4\u591a\u75c5\u60a3\u3002\u201d<\/p>\n

\u5173\u4e8e\u5fb7\u742a<\/b><\/p>\n

\u5fb7\u742a\u533b\u836f\u6709\u9650\u516c\u53f8\uff08\u7b80\u79f0\u201c\u5fb7\u742a\u533b\u836f\u201d\uff0c\u9999\u6e2f\u8054\u4ea4\u6240\u80a1\u7968\u4ee3\u7801\uff1a6996.HK\uff09\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u521b\u65b0\u6297\u80bf\u7624\u836f\u7269\u7684\u4e9a\u592a\u5730\u533a\u4e34\u5e8a\u9636\u6bb5\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u65e8\u5728\u4e3a\u4e2d\u56fd\u3001\u4e9a\u592a\u5730\u533a\u53ca\u5168\u7403\u5404\u5730\u7684\u60a3\u8005\u63d0\u4f9b\u6700\u524d\u6cbf\u7684\u6297\u80bf\u7624\u521b\u65b0\u7597\u6cd5\u3002\u81ea\u6210\u7acb\u4ee5\u6765\uff0c\u5fb7\u742a\u533b\u836f\u5df2\u5efa\u7acb\u8d77\u62e5\u670912\u6b3e\u4e34\u5e8a\u53ca\u4e34\u5e8a\u524d\u521b\u65b0\u836f\u7269\u7684\u4e30\u5bcc\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u5e76\u5728\u4e9a\u592a\u5730\u533a\u53d6\u5f9712\u4e2a\u4e34\u5e8a\u8bd5\u9a8c\u6279\u4ef6\u3002\u5fb7\u742a\u4eba\u4ee5\u201c\u533b\u8005\u65e0\u7586\uff0c\u521b\u65b0\u6c38\u7eed\u201d\u4e3a\u613f\u666f\uff0c\u529b\u4e89\u901a\u8fc7\u5bf9\u540c\u7c7b\u9996\u6b3e\/\u540c\u7c7b\u6700\u4f18\u7597\u6cd5\u7684\u4e13\u7814\u4e0e\u5e02\u573a\u5316\uff0c\u89e3\u51b3\u4e9a\u592a\u4e43\u81f3\u5168\u7403\u60a3\u8005\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002\u6b32\u4e86\u89e3\u66f4\u591a\uff0c\u8bf7\u8bbf\u95ee\uff1awww.antengene.com<\/a>\u4ee5\u53ca\u5173\u6ce8\u201cAntengene\u201d\u9886\u82f1\u8d26\u53f7\u3002<\/p>\n

\u5173\u4e8e\u836f\u660e\u751f\u7269<\/b><\/p>\n

\u836f\u660e\u751f\u7269\uff08\u80a1\u7968\u4ee3\u7801\uff1a2269.HK\uff09\u4f5c\u4e3a\u4e00\u5bb6\u9999\u6e2f\u4e0a\u5e02\u516c\u53f8\uff0c\u662f\u5168\u7403\u9886\u5148\u7684\u5f00\u653e\u5f0f\u3001\u4e00\u4f53\u5316\u751f\u7269\u5236\u836f\u80fd\u529b\u548c\u6280\u672f\u8d4b\u80fd\u5e73\u53f0\u3002\u516c\u53f8\u4e3a\u5168\u7403\u751f\u7269\u5236\u836f\u516c\u53f8\u548c\u751f\u7269\u6280\u672f\u516c\u53f8\u63d0\u4f9b\u5168\u65b9\u4f4d\u7684\u7aef\u5230\u7aef\u7814\u53d1\u670d\u52a1\uff0c\u5e2e\u52a9\u4efb\u4f55\u4eba\u3001\u4efb\u4f55\u516c\u53f8\u53d1\u73b0\u3001\u5f00\u53d1\u53ca\u751f\u4ea7\u751f\u7269\u836f\uff0c\u5b9e\u73b0\u4ece\u6982\u5ff5\u5230\u5546\u4e1a\u5316\u751f\u4ea7\u7684\u5168\u8fc7\u7a0b\uff0c\u52a0\u901f\u5168\u7403\u751f\u7269\u836f\u7814\u53d1\u8fdb\u7a0b\uff0c\u964d\u4f4e\u7814\u53d1\u6210\u672c\uff0c\u9020\u798f\u75c5\u60a3\u3002\u622a\u81f32020\u5e746\u670830\u65e5\uff0c\u5728\u836f\u660e\u751f\u7269\u5e73\u53f0\u4e0a\u7814\u53d1\u7684\u7efc\u5408\u9879\u76ee\u8fbe286\u4e2a\uff0c\u5305\u62ec141\u4e2a\u5904\u4e8e\u4e34\u5e8a\u524d\u7814\u7a76\u9636\u6bb5\uff0c125\u4e2a\u5728\u4e34\u5e8a\u65e9\u671f\uff08I\u671f\uff0cII\u671f\uff09\u9636\u6bb5\uff0c19\u4e2a\u5728\u540e\u671f\u4e34\u5e8a\uff08III\u671f\uff09\u4ee5\u53ca1\u4e2a\u5728\u5546\u4e1a\u5316\u751f\u4ea7\u9636\u6bb5\u3002\u9884\u8ba1\u52302023\u5e74\u540e\uff0c\u516c\u53f8\u5728\u4e2d\u56fd\u3001\u7231\u5c14\u5170\u3001\u7f8e\u56fd\u3001\u5fb7\u56fd\u548c\u65b0\u52a0\u5761\u89c4\u5212\u7684\u751f\u7269\u5236\u836f\u751f\u4ea7\u57fa\u5730\u5408\u8ba1\u4ea7\u80fd\u5c06\u8d85\u8fc730\u4e07\u5347\uff0c\u8fd9\u5c06\u6709\u529b\u786e\u4fdd\u516c\u53f8\u901a\u8fc7\u5065\u5168\u5f3a\u5927\u7684\u5168\u7403\u4f9b\u5e94\u94fe\u7f51\u7edc\u4e3a\u5ba2\u6237\u63d0\u4f9b\u7b26\u5408\u5168\u7403\u8d28\u91cf\u6807\u51c6\u7684\u751f\u7269\u836f\u3002\u5982\u9700\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1awww.wuxibiologics.com<\/a>\u3002<\/p>\n

\u5173\u4e8e\u5408\u5168\u836f\u4e1a<\/b><\/p>\n

\u5408\u5168\u836f\u4e1a\u662f\u5728\u4e2d\u7f8e\u4e24\u5730\u5747\u6709\u8fd0\u8425\u7684\u836f\u660e\u5eb7\u5fb7\u5b50\u516c\u53f8\uff0c\u670d\u52a1\u4e8e\u751f\u547d\u79d1\u5b66\u884c\u4e1a\uff0c\u62e5\u6709\u5353\u8d8a\u7684\u5316\u5b66\u521b\u65b0\u836f\u7814\u53d1\u548c\u751f\u4ea7\u7684\u80fd\u529b\u548c\u6280\u672f\u5e73\u53f0\u3002\u4f5c\u4e3a\u5168\u7403\u65b0\u836f\u5408\u4f5c\u7814\u7a76\u5f00\u53d1\u751f\u4ea7\u9886\u57df\uff08CDMO\uff09\u7684\u9886\u519b\u4f01\u4e1a\uff0c\u5408\u5168\u836f\u4e1a\u81f4\u529b\u4e8e\u4e3a\u5168\u7403\u5408\u4f5c\u4f19\u4f34\u63d0\u4f9b\u4ece\u4e34\u5e8a\u524d\u5230\u5546\u4e1a\u5316\uff0c\u9ad8\u6548\u3001\u7075\u6d3b\u3001\u9ad8\u8d28\u91cf\u7684\u4e00\u7ad9\u5f0fCMC\uff08\u5316\u5b66\u3001\u751f\u4ea7\u548c\u63a7\u5236\uff09\u89e3\u51b3\u65b9\u6848\u3002\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9\uff1awww.STApharma.com.cn<\/a> <\/p>\n

\u76f8\u5173\u94fe\u63a5 :<\/p>\n

http:\/\/www.antengene.com<\/p>\n","protected":false},"excerpt":{"rendered":"

\u4e0a\u6d77\u548c\u9999\u6e2f2021\u5e742\u67081\u65e5 \/\u7f8e\u901a\u793e\/ — \u81f4\u529b\u4e8e\u7814\u53d1\u548c\u5546\u4e1a\u5316\u521b\u65b0\u80bf\u7624\u7597\u6cd5\u7684\u751f\u7269\u5236\u836f\u516c\u53f8 — \u5fb7\u742a\u533b\u836f\u6709\u9650\u516c\u53f8\uff08\u7b80\u79f0\u201c\u5fb7\u742a\u533b\u836f\u201d\uff0c6996.HK\uff09\u4e0e\u5168\u7403\u9886\u5148\u7684\u5f00\u653e\u5f0f\u751f\u7269\u5236\u836f\u6280\u672f\u5e73\u53f0\u516c\u53f8\u836f\u660e\u751f\u7269\uff08WuXi Biologics, 2269.HK\uff09\u53ca\u5168\u7403\u9886\u5148\u7684\u65b0\u836f\u7814\u53d1\u751f\u4ea7CDMO\u4f01\u4e1a\u5408\u5168\u836f\u4e1a\u4eca\u65e5\u5ba3\u5e03\uff0c\u4e09\u65b9\u8fbe\u6210\u6218\u7565\u5408\u4f5c\uff0c\u5171\u540c\u52a0\u901f\u521b\u65b0\u6297\u4f53\u5076\u8054\u836f\u7269\uff08Antibody-Drug Conjugate, ADC\uff09\u7684\u7814\u53d1\u751f\u4ea7\u3002\u8fd9\u4e5f\u662f\u81ea2020\u5e7410\u6708\u5fb7\u742a\u533b\u836f\u4e0e\u836f\u660e\u751f\u7269\u9488\u5bf9\u53cc\u7279\u5f02\u6027\u6297\u4f53\u8fbe\u6210CDMO\u5408\u4f5c\u540e\uff0c\u53cc\u65b9\u7b2c\u4e8c\u6b21\u5728GMP\u751f\u4ea7\u65b9\u9762\u5efa\u7acb\u5408\u4f5c\u3002\u5fb7\u742a\u533b\u836f\u5c06\u57fa\u4e8e\u81ea\u8eab\u7684\u7814\u53d1\u4f18\u52bf\uff0c\u901a\u8fc7\u201c\u5e73\u53f0+\u81ea\u7814\u201d\u5e76\u884c\u7684\u7b56\u7565\uff0c\u63d0\u9ad8ADC\u836f\u7269\u7b49\u65e9\u671f\u7814\u53d1\u9879\u76ee\u7684\u5b75\u5316\u6548\u7387\u3002 \u9488\u5bf9\u56fd\u5185\u53ca\u4e9a\u592a\u60a3\u8005\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u5fb7\u742a\u533b\u836f\u81ea\u4e3b\u7814\u53d1\u4e0e\u5408\u4f5c\u5f15\u8fdb\u9f50\u5934\u5e76\u8fdb\uff0c\u5e03\u5c40\u4e86\u5305\u62ecADC\u836f\u7269\u5728\u5185\u76846\u6b3e\u521b\u65b0\u578b\u65e9\u671f\u7814\u53d1\u9879\u76ee\u3002\u5728\u7814\u53d1\u56e2\u961f\u6301\u7eed\u6709\u529b\u5730\u63a8\u8fdb\u4e0b\uff0c\u591a\u6b3e\u65e9\u671f\u836f\u7269\u9646\u7eed\u8fdb\u5165\u7814\u53d1\u751f\u4ea7\u9636\u6bb5\u3002ADC\u662f\u4e00\u79cd\u901a\u8fc7\u8fde\u63a5\u5b50\uff08linker\uff09\u5c06\u5177\u6709\u80bf\u7624\u7ec6\u80de\u6740\u4f24\u529b\u7684\u5c0f\u5206\u5b50\u836f\u7269\u5076\u8054\u81f3\u5355\u514b\u9686\u6297\u4f53\u4e0a\u800c\u4ea7\u751f\u7684\u590d\u5408\u4f53\u836f\u7269\uff0c\u51ed\u501f\u5176\u9ad8\u7cbe\u51c6\u5ea6\u548c\u663e\u8457\u7684\u6cbb\u7597\u6548\u679c\uff0c\u5df2\u9010\u6e10\u6210\u4e3a\u80bf\u7624\u9776\u5411\u6cbb\u7597\u9886\u57df\u7684\u65b0\u5174\u7597\u6cd5\u3002\u6b64\u6b21\u6218\u7565\u5408\u4f5c\uff0c\u836f\u660e\u751f\u7269\u4e0e\u5408\u5168\u836f\u4e1a\u5c06\u4e3a\u5fb7\u742a\u533b\u836fADC\u836f\u7269\u5f00\u53d1\u63d0\u4f9b\u4ea7\u54c1\u4e2d\u95f4\u4f53\u7684\u89c4\u6a21\u653e\u5927\u3001\u5de5\u827a\u5f00\u53d1\u548cGMP\u751f\u4ea7\u670d\u52a1\u3002\u5176\u4e2d\uff0c\u5fb7\u742a\u533b\u836f\u4e13\u6ce8\u4e8e\u6297\u4f53\u5076\u8054\u836f\u7269\u7684\u6838\u5fc3\u8981\u7d20 — \u5355\u514b\u9686\u6297\u4f53\u7684\u7814\u53d1\uff1b\u5408\u5168\u836f\u4e1a\u4e13\u6ce8\u4e8e\u8fde\u63a5\u4f53\u548c\u6709\u6548\u8f7d\u8377\uff08payload\uff09\u7684GMP\u751f\u4ea7\uff1b\u836f\u660e\u751f\u7269\u4e13\u6ce8\u4e8e\u5355\u514b\u9686\u6297\u4f53\uff08mAb\uff09\uff0c\u751f\u7269\u5076\u8054\u548c\u6210\u54c1\u51bb\u5e72\u5de5\u827a\u5f00\u53d1\uff0c\u5e76\u4ee5GMP\u6807\u51c6\u751f\u4ea7\u5076\u8054\u539f\u6db2\u548c\u51bb\u5e72\u5236\u5242\u3002\u4e09\u65b9\u5c06\u901a\u8fc7\u8d44\u6e90\u5339\u914d\u548c\u6280\u672f\u4e92\u8865\uff0c\u4fc3\u4f7fADC\u836f\u7269\u6982\u5ff5\u843d\u5730\uff0c\u4e3a\u60a3\u8005\u63d0\u4f9b\u884c\u4e4b\u6709\u6548\u7684\u6cbb\u7597\u624b\u6bb5\u3002 \u5fb7\u742a\u533b\u836f\u521b\u59cb\u4eba\u3001\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u6885\u5efa\u660e\u535a\u58eb\u8868\u793a\uff1a\u201c\u5f88\u9ad8\u5174\u5fb7\u742a\u4e0e\u836f\u660e\u751f\u7269\u3001\u5408\u5168\u836f\u4e1a\u5efa\u7acb\u7684\u9ad8\u6548\u7a33\u5b9a\u7684\u5408\u4f5c\u5173\u7cfb\u3002\u6211\u4eec\u4e00\u76f4\u6ce8\u91cd\u81ea\u4e3b\u7814\u53d1\u4f53\u7cfb\u7684\u642d\u5efa\uff0c\u901a\u8fc7\u5efa\u7acb\u5fb7\u742a\u65b0\u836f\u7814\u53d1\u4e2d\u5fc3\uff0c\u5168\u9762\u5e03\u5c40\u65e9\u671f\u7814\u53d1\u9879\u76ee\uff1b\u6211\u4eec\u7acb\u8db3\u8054\u5408\u4e0e\u4e92\u8865\u7684\u6218\u7565\uff0c\u901a\u8fc7\u4e34\u5e8a\u56e2\u961f\u3001\u6ce8\u518c\u56e2\u961f\u548c\u65e9\u671f\u7814\u53d1\u56e2\u961f\u7684\u6574\u5408\uff0c\u66f4\u9ad8\u6548\u5730\u63a8\u8fdb\u836f\u7269\u7814\u53d1\u9879\u76ee\u3002\u76f8\u4fe1\u5408\u5168\u836f\u4e1a\u53ca\u836f\u660e\u751f\u7269\u5728ADC\u836f\u7269\u9886\u57df\u7684\u6df1\u539a\u79ef\u6dc0\u5c06\u4e0e\u5fb7\u742a\u7684\u521b\u65b0\u7406\u5ff5\u76f8\u7ed3\u5408\uff0c\u5f62\u6210\u66f4\u5f3a\u5927\u7684\u6280\u672f\u5408\u529b\uff0c\u52a0\u901fADC\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u53ca\u5e94\u7528\uff0c\u65e9\u65e5\u9020\u798f\u75c5\u60a3\u3002\u201d \u5fb7\u742a\u533b\u836f\u96c6\u56e2\u526f\u603b\u88c1\u3001\u65e9\u671f\u836f\u7269\u7814\u53d1\u53ca\u836f\u7269\u751f\u4ea7\u8d1f\u8d23\u4eba\u5355\u6ce2\u535a\u58eb\u8868\u793a\uff1a\u201c\u76ee\u524d\uff0c\u5fb7\u742a\u65e9\u671f\u7814\u53d1\u7684\u8282\u594f\u4e0d\u65ad\u52a0\u5feb\uff0cADC\u836f\u7269\u6cbb\u7597\u4f18\u52bf\u660e\u663e\uff0c\u9002\u7528\u4eba\u7fa4\u5e7f\u6cdb\uff0c\u62e5\u6709\u5de8\u5927\u7684\u5e02\u573a\u6f5c\u529b\u3002\u76f8\u4fe1\u6b64\u6b21\u5408\u4f5c\u540e\uff0c\u5fb7\u742a\u5c06\u4ee5\u66f4\u9ad8\u6807\u51c6\u7684\u751f\u4ea7\u5de5\u827a\u548c\u8d28\u91cf\u4f53\u7cfb\uff0c\u7814\u53d1\u751f\u4ea7\u9ad8\u8d28\u91cf\u7684ADC\u836f\u7269\uff0c\u5728\u5168\u7403\u521b\u65b0\u836f\u7269\u7814\u53d1\u4e0a\u4e0d\u65ad\u63d0\u9ad8\u6838\u5fc3\u7ade\u4e89\u529b\u3002\u201d \u836f\u660e\u751f\u7269\u9996\u5e2d\u6267\u884c\u5b98\u9648\u667a\u80dc\u535a\u58eb\u8868\u793a\uff1a\u201c\u6211\u4eec\u975e\u5e38\u9ad8\u5174\u4e0e\u5fb7\u742a\u533b\u836f\u6269\u5927\u6218\u7565\u5408\u4f5c\uff0c\u901a\u8fc7\u836f\u660e\u751f\u7269\u5353\u8d8a\u7684\u751f\u7269\u6280\u672f\u5e73\u53f0\u3001\u5145\u8db3\u7684\u4ea7\u80fd\u4ee5\u53ca\u9ad8\u8d28\u91cf\u6807\u51c6\uff0c\u52a0\u901f\u5c06\u5fb7\u742a\u533b\u836f\u521b\u65b0ADC\u836f\u7269\u63a8\u8fdb\u81f3\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002\u836f\u660e\u751f\u7269\u5c06\u6301\u7eed\u5728ADC\u836f\u7269\u9886\u57df\u592f\u5b9e\u80fd\u529b\u548c\u89c4\u6a21\u5efa\u8bbe\uff0c\u8d4b\u80fd\u5168\u7403\u5408\u4f5c\u4f19\u4f34\u62e5\u62b1\u65b0\u4e00\u4ee3\u751f\u7269\u836f\u6d6a\u6f6e\uff0c\u65e9\u65e5\u9020\u798f\u5e7f\u5927\u60a3\u8005\u3002\u201d \u5408\u5168\u836f\u4e1a\u9996\u5e2d\u6267\u884c\u5b98\u9648\u6c11\u7ae0\u535a\u58eb\u8868\u793a\uff1a\u201c\u975e\u5e38\u9ad8\u5174\u4e0e\u5fb7\u742a\u533b\u836f\u8fdb\u4e00\u6b65\u6269\u5927\u5408\u4f5c\u7684\u8303\u56f4\u4e0e\u6df1\u5ea6\uff0c\u76f8\u4fe1\u5408\u5168\u836f\u4e1a\u5728\u9ad8\u6d3b\u539f\u6599\u836f\u65b9\u9762\u548c\u6d89\u53caADC\u7b49\u65b0\u578b\u836f\u7269\u5206\u5b50\u7684\u5076\u8054\u5316\u5b66\u65b9\u9762\u7684\u9886\u5148\u80fd\u529b\u548c\u89c4\u6a21\u4f18\u52bf\uff0c\u4ee5\u53ca\u7b26\u5408\u5168\u7403\u6807\u51c6\u7684\u8d28\u91cf\u4f53\u7cfb\uff0c\u5c06\u4e3a\u5fb7\u742a\u533b\u836fADC\u836f\u7269\u9879\u76ee\u63d0\u4f9b\u5f3a\u6709\u529b\u7684\u652f\u6491\u3002\u5408\u5168\u836f\u4e1a\u5c06\u7ee7\u7eed\u63d0\u5347\u65b0\u578b\u836f\u7269\u5206\u5b50\u4ece\u4e34\u5e8a\u524d\u81f3\u5546\u4e1a\u5316\u7684\u4e00\u4f53\u5316CMC\u80fd\u529b\uff0c\u8d4b\u80fd\u66f4\u591a\u5168\u7403\u5408\u4f5c\u4f19\u4f34\uff0c\u60e0\u53ca\u66f4\u591a\u75c5\u60a3\u3002\u201d \u5173\u4e8e\u5fb7\u742a \u5fb7\u742a\u533b\u836f\u6709\u9650\u516c\u53f8\uff08\u7b80\u79f0\u201c\u5fb7\u742a\u533b\u836f\u201d\uff0c\u9999\u6e2f\u8054\u4ea4\u6240\u80a1\u7968\u4ee3\u7801\uff1a6996.HK\uff09\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u521b\u65b0\u6297\u80bf\u7624\u836f\u7269\u7684\u4e9a\u592a\u5730\u533a\u4e34\u5e8a\u9636\u6bb5\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u65e8\u5728\u4e3a\u4e2d\u56fd\u3001\u4e9a\u592a\u5730\u533a\u53ca\u5168\u7403\u5404\u5730\u7684\u60a3\u8005\u63d0\u4f9b\u6700\u524d\u6cbf\u7684\u6297\u80bf\u7624\u521b\u65b0\u7597\u6cd5\u3002\u81ea\u6210\u7acb\u4ee5\u6765\uff0c\u5fb7\u742a\u533b\u836f\u5df2\u5efa\u7acb\u8d77\u62e5\u670912\u6b3e\u4e34\u5e8a\u53ca\u4e34\u5e8a\u524d\u521b\u65b0\u836f\u7269\u7684\u4e30\u5bcc\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u5e76\u5728\u4e9a\u592a\u5730\u533a\u53d6\u5f9712\u4e2a\u4e34\u5e8a\u8bd5\u9a8c\u6279\u4ef6\u3002\u5fb7\u742a\u4eba\u4ee5\u201c\u533b\u8005\u65e0\u7586\uff0c\u521b\u65b0\u6c38\u7eed\u201d\u4e3a\u613f\u666f\uff0c\u529b\u4e89\u901a\u8fc7\u5bf9\u540c\u7c7b\u9996\u6b3e\/\u540c\u7c7b\u6700\u4f18\u7597\u6cd5\u7684\u4e13\u7814\u4e0e\u5e02\u573a\u5316\uff0c\u89e3\u51b3\u4e9a\u592a\u4e43\u81f3\u5168\u7403\u60a3\u8005\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002\u6b32\u4e86\u89e3\u66f4\u591a\uff0c\u8bf7\u8bbf\u95ee\uff1awww.antengene.com\u4ee5\u53ca\u5173\u6ce8\u201cAntengene\u201d\u9886\u82f1\u8d26\u53f7\u3002 \u5173\u4e8e\u836f\u660e\u751f\u7269 \u836f\u660e\u751f\u7269\uff08\u80a1\u7968\u4ee3\u7801\uff1a2269.HK\uff09\u4f5c\u4e3a\u4e00\u5bb6\u9999\u6e2f\u4e0a\u5e02\u516c\u53f8\uff0c\u662f\u5168\u7403\u9886\u5148\u7684\u5f00\u653e\u5f0f\u3001\u4e00\u4f53\u5316\u751f\u7269\u5236\u836f\u80fd\u529b\u548c\u6280\u672f\u8d4b\u80fd\u5e73\u53f0\u3002\u516c\u53f8\u4e3a\u5168\u7403\u751f\u7269\u5236\u836f\u516c\u53f8\u548c\u751f\u7269\u6280\u672f\u516c\u53f8\u63d0\u4f9b\u5168\u65b9\u4f4d\u7684\u7aef\u5230\u7aef\u7814\u53d1\u670d\u52a1\uff0c\u5e2e\u52a9\u4efb\u4f55\u4eba\u3001\u4efb\u4f55\u516c\u53f8\u53d1\u73b0\u3001\u5f00\u53d1\u53ca\u751f\u4ea7\u751f\u7269\u836f\uff0c\u5b9e\u73b0\u4ece\u6982\u5ff5\u5230\u5546\u4e1a\u5316\u751f\u4ea7\u7684\u5168\u8fc7\u7a0b\uff0c\u52a0\u901f\u5168\u7403\u751f\u7269\u836f\u7814\u53d1\u8fdb\u7a0b\uff0c\u964d\u4f4e\u7814\u53d1\u6210\u672c\uff0c\u9020\u798f\u75c5\u60a3\u3002\u622a\u81f32020\u5e746\u670830\u65e5\uff0c\u5728\u836f\u660e\u751f\u7269\u5e73\u53f0\u4e0a\u7814\u53d1\u7684\u7efc\u5408\u9879\u76ee\u8fbe286\u4e2a\uff0c\u5305\u62ec141\u4e2a\u5904\u4e8e\u4e34\u5e8a\u524d\u7814\u7a76\u9636\u6bb5\uff0c125\u4e2a\u5728\u4e34\u5e8a\u65e9\u671f\uff08I\u671f\uff0cII\u671f\uff09\u9636\u6bb5\uff0c19\u4e2a\u5728\u540e\u671f\u4e34\u5e8a\uff08III\u671f\uff09\u4ee5\u53ca1\u4e2a\u5728\u5546\u4e1a\u5316\u751f\u4ea7\u9636\u6bb5\u3002\u9884\u8ba1\u52302023\u5e74\u540e\uff0c\u516c\u53f8\u5728\u4e2d\u56fd\u3001\u7231\u5c14\u5170\u3001\u7f8e\u56fd\u3001\u5fb7\u56fd\u548c\u65b0\u52a0\u5761\u89c4\u5212\u7684\u751f\u7269\u5236\u836f\u751f\u4ea7\u57fa\u5730\u5408\u8ba1\u4ea7\u80fd\u5c06\u8d85\u8fc730\u4e07\u5347\uff0c\u8fd9\u5c06\u6709\u529b\u786e\u4fdd\u516c\u53f8\u901a\u8fc7\u5065\u5168\u5f3a\u5927\u7684\u5168\u7403\u4f9b\u5e94\u94fe\u7f51\u7edc\u4e3a\u5ba2\u6237\u63d0\u4f9b\u7b26\u5408\u5168\u7403\u8d28\u91cf\u6807\u51c6\u7684\u751f\u7269\u836f\u3002\u5982\u9700\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1awww.wuxibiologics.com\u3002 \u5173\u4e8e\u5408\u5168\u836f\u4e1a \u5408\u5168\u836f\u4e1a\u662f\u5728\u4e2d\u7f8e\u4e24\u5730\u5747\u6709\u8fd0\u8425\u7684\u836f\u660e\u5eb7\u5fb7\u5b50\u516c\u53f8\uff0c\u670d\u52a1\u4e8e\u751f\u547d\u79d1\u5b66\u884c\u4e1a\uff0c\u62e5\u6709\u5353\u8d8a\u7684\u5316\u5b66\u521b\u65b0\u836f\u7814\u53d1\u548c\u751f\u4ea7\u7684\u80fd\u529b\u548c\u6280\u672f\u5e73\u53f0\u3002\u4f5c\u4e3a\u5168\u7403\u65b0\u836f\u5408\u4f5c\u7814\u7a76\u5f00\u53d1\u751f\u4ea7\u9886\u57df\uff08CDMO\uff09\u7684\u9886\u519b\u4f01\u4e1a\uff0c\u5408\u5168\u836f\u4e1a\u81f4\u529b\u4e8e\u4e3a\u5168\u7403\u5408\u4f5c\u4f19\u4f34\u63d0\u4f9b\u4ece\u4e34\u5e8a\u524d\u5230\u5546\u4e1a\u5316\uff0c\u9ad8\u6548\u3001\u7075\u6d3b\u3001\u9ad8\u8d28\u91cf\u7684\u4e00\u7ad9\u5f0fCMC\uff08\u5316\u5b66\u3001\u751f\u4ea7\u548c\u63a7\u5236\uff09\u89e3\u51b3\u65b9\u6848\u3002\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9\uff1awww.STApharma.com.cn \u76f8\u5173\u94fe\u63a5 : http:\/\/www.antengene.com… Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":8278,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-19234","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/19234","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=19234"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/19234\/revisions"}],"predecessor-version":[{"id":19235,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/19234\/revisions\/19235"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/8278"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=19234"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=19234"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=19234"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}