{"id":16481,"date":"2021-01-04T07:00:00","date_gmt":"2021-01-04T00:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2021010407000016481"},"modified":"2021-01-04T09:13:52","modified_gmt":"2021-01-04T01:13:52","slug":"%e5%be%b7%e7%90%aa%e5%8c%bb%e8%8d%af%e5%9c%a8%e9%9f%a9%e5%9b%bd%e6%8f%90%e4%ba%a4atg-010%ef%bc%88selinexor%ef%bc%89%e7%9a%84%e6%96%b0%e8%8d%af%e4%b8%8a%e5%b8%82%e7%94%b3%e8%af%b7%ef%bc%8c%e7%94%a8","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2021010407000016481","title":{"rendered":"\u5fb7\u742a\u533b\u836f\u5728\u97e9\u56fd\u63d0\u4ea4ATG-010\uff08Selinexor\uff09\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff0c\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u53ca\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624"},"content":{"rendered":"

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ATG-010<\/b>\uff08<\/b>selinexor<\/b>\uff0c<\/b>XPOVIO<\/b>®<\/sup>\uff09\u662f\u540c\u7c7b\u9996\u6b3e\u4e14\u552f\u4e00\u4e00\u6b3e\u53e3\u670d\u578b\u9009\u62e9\u6027\u6838\u8f93\u51fa\u6291\u5236\u5242\uff08<\/b>SINE<\/b>\uff09\uff0c\u4e5f\u662f\u9996\u6b3e\u83b7<\/b>FDA<\/b>\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u4e0e\u5f25\u6f2b\u6027\u5927<\/b>B<\/b>\u7ec6\u80de\u6dcb\u5df4\u7624\u7684\u836f\u7269\u3002<\/b>2020\u5e7412\u6708\uff0c\u7f8e\u56fd\u56fd\u5bb6\u7efc\u5408\u764c\u75c7\u7f51\u7edc\uff08NCCN®<\/sup>\uff09\u5c06\u4e09\u79cdATG-010\uff08selinexor\uff0cXPOVIO®<\/sup>\uff09\u6cbb\u7597\u590d\u53d1\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u7684\u8054\u5408\u65b9\u6848\u7eb3\u5165\u4e34\u5e8a\u5b9e\u8df5\u6307\u5357\uff08NCCN®<\/sup> Guidelines\uff09\uff0c\u5305\u62ecSVd\uff08selinexor\u3001bortezomib\u4e0edexamethasone\uff09\uff0cSPd\uff08selinexor\u3001pomalidomide\u4e0edexamethasone\uff09\u548cSDd\uff08selinexor\u3001daratumumab\u4e0edexamethasone\uff09\u65b9\u6848\u3002\u5fb7\u742a\u533b\u836f\u5df2\u5411\u65b0\u52a0\u5761\u536b\u751f\u79d1\u5b66\u5c40\uff08<\/b>HSA<\/b>\uff09\u548c\u6fb3\u5927\u5229\u4e9a\u533b\u7597\u7528\u54c1\u7ba1\u7406\u5c40\uff08<\/b>TGA<\/b>\uff09\u9012\u4ea4\u4e86<\/b>ATG-010<\/b>\uff08<\/b>selinexor<\/b>\uff0c<\/b>XPOVIO<\/b>®<\/sup>\uff09\u7528\u4e8e\u6cbb\u7597<\/b>rrMM<\/b>\u548c<\/b>rrDLBCL<\/b>\u60a3\u8005\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u3002<\/b><\/p>\n

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\u5fb7\u742a\u533b\u836f\u6b63\u5728\u4e2d\u56fd\u8fdb\u884cATG-010\uff08selinexor\uff0cXPOVIO®<\/sup>\uff09\u9488\u5bf9\u590d\u53d1\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u76842\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u7814\u7a76\uff08\u4ee3\u53f7MARCH\uff09\u4ee5\u53ca\u9488\u5bf9\u590d\u53d1\u96be\u6cbb\u6027\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u76242\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u7814\u7a76\uff08\u4ee3\u53f7SEARCH\uff09\u3002\u540c\u65f6\uff0c\u5fb7\u742a\u533b\u836f\u9488\u5bf9\u4e9a\u592a\u9ad8\u53d1\u7624\u79cd\u542f\u52a8\u4e86ATG-010\uff08selinexor\uff0cXPOVIO®<\/sup>\uff09\u7528\u4e8e\u6cbb\u7597\u5916\u5468T\u7ec6\u80de\u6dcb\u5df4\u7624\u3001NK\/T\u7ec6\u80de\u6dcb\u5df4\u7624\uff08\u4ee3\u53f7TOUCH\uff09\u53caKRAS\u7a81\u53d8\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u4e34\u5e8a\u7814\u7a76\uff08\u4ee3\u53f7TRUMP\uff09\u3002<\/p>\n

\u5173\u4e8e\u5fb7\u742a\u533b\u836f<\/b><\/p>\n

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\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n

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XPOVIO®\u4e3aKaryopharm Therapeutics Inc.\u6ce8\u518c\u5546\u6807\uff1b<\/p>\n

NCCN®\u4e3a\u7f8e\u56fd\u56fd\u5bb6\u7efc\u5408\u764c\u75c7\u7f51\u7edc\u6ce8\u518c\u5546\u6807\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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