{"id":14871,"date":"2020-12-18T10:00:00","date_gmt":"2020-12-18T03:00:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2020121810000014871"},"modified":"2020-12-19T09:14:03","modified_gmt":"2020-12-19T01:14:03","slug":"%e8%85%be%e7%9b%9b%e5%8d%9a%e8%8d%af%e7%a0%94%e5%8f%91%e6%88%98%e7%95%a5%e5%8f%96%e5%be%97%e9%87%8d%e5%a4%a7%e8%bf%9b%e5%b1%95","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2020121810000014871","title":{"rendered":"\u817e\u76db\u535a\u836f\u7814\u53d1\u6218\u7565\u53d6\u5f97\u91cd\u5927\u8fdb\u5c55"},"content":{"rendered":"<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" title=\"logo\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/Logo-20.jpg\" alt=\"\" width=\"118\" border=\"0\" hspace=\"0\" vspace=\"0\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul type=\"disc\">\n<li><em>\u4e0e\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662(NIH)\u8fc7\u654f\u548c\u4f20\u67d3\u75c5\u7814\u7a76\u6240(NIAID)\u5408\u4f5c\u5f00\u5c55\u7814\u7a76\u6027\u5355\u514b\u9686\u6297\u4f53BRII-196\u548cBRII-198\u8054\u5408\u7528\u836f\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u7528\u4e8e\u6cbb\u7597\u65b0\u51a0\u80ba\u708e\uff08COVID-19\uff09<\/em><\/li>\n<li><em>\u6301\u7eed\u5feb\u901f\u63a8\u8fdb\u5728\u7814\u65b0\u836f\u7684\u5f00\u53d1\u5de5\u4f5c\uff0c\u4ee5\u5bf9\u6297\u4e59\u578b\u809d\u708e\uff08HBV\uff09\u3001\u591a\u91cd\u8010\u836f\u9769\u5170\u6c0f\u9634\u6027\u83cc\u611f\u67d3\u4ee5\u53ca\u827e\u6ecb\u75c5\uff08HIV\uff09\u7b49\u4f20\u67d3\u75c5\u7684\u4e25\u91cd\u5a01\u80c1<\/em><\/li>\n<li><em>\u9ad8\u6548\u63a8\u8fdb\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u9879\u76ee\uff0c\u8ba1\u5212\u4e8e2021\u5e741\u6708\u63d0\u4ea4BRII-296\u7684\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7<\/em><\/li>\n<li><em>\u7f8e\u56fd\u9886\u5bfc\u56e2\u961f\u8fdb\u884c\u4eba\u4e8b\u4efb\u547d\u5e76\u8fdb\u4e00\u6b65\u58ee\u5927<\/em><\/li>\n<\/ul>\n<p><p>\u5317\u4eac\u4e0e\u5317\u5361\u7f57\u6765\u7eb3\u5dde\u8fbe\u52d2\u59c6\u5e022020\u5e7412\u670818\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; <span id=\"spanHghlt8c45\">\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f42020\u5e7412\u670817\u65e5\uff0c<\/span>\u817e\u76db\u535a\u836f\uff08Brii Biosciences\uff09\uff0c\u4e00\u5bb6\u6a2a\u8de8\u4e2d\u7f8e\uff0c\u81f4\u529b\u4e8e\u5f00\u53d1\u521b\u65b0\u836f\u7269\u4ee5\u670d\u52a1\u60a3\u8005\u9700\u6c42\uff0c\u5e76\u63d0\u5347\u5168\u7403\u548c\u4e2d\u56fd\u516c\u5171\u536b\u751f\u6c34\u5e73\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c<span id=\"spanHghltbce0\">\u4eca\u5929<\/span>\u53d1\u5e03\u4e86\u516c\u53f8\u6700\u65b0\u7814\u53d1\u52a8\u6001\u3002\u516c\u53f8\u76846\u79cd\u6cbb\u7597\u5019\u9009\u836f\u7269\u5728\u7814\u53d1\u65b9\u9762\u53d6\u5f97\u4e86\u91cd\u5927\u8fdb\u5c55\uff0c\u8fd9\u4e9b\u836f\u7269\u7528\u4e8e\u5e94\u5bf9<span id=\"spanHghlte19d\">\u4e16\u754c\u4e0a\u6781\u5176\u4e25\u91cd<\/span>\u7684\u4f20\u67d3\u75c5\u5a01\u80c1\uff0c\u5305\u62ec\u65b0\u51a0\u80ba\u708e\u3001\u4e59\u578b\u809d\u708e\u548c\u591a\u91cd\u8010\u836f\u9769\u5170\u6c0f\u9634\u6027\u83cc\u611f\u67d3\u7b49\u3002<\/p>\n<div id=\"DivAssetPlaceHolder7895\" class=\"PRN_ImbeddedAssetReference\">\n<p style=\"text-align: center;width: 100%\"><a href=\"https:\/\/mma.prnasia.com\/media2\/1388803\/image1.html\" rel=\"nofollow noopener noreferrer\" target=\"_blank\"><img decoding=\"async\" title=\"\u817e\u76db\u535a\u836f\u9879\u76ee\u8fdb\u5c55\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/image1-261.jpg\" alt=\"\u817e\u76db\u535a\u836f\u9879\u76ee\u8fdb\u5c55\" \/><\/a><br \/><span>\u817e\u76db\u535a\u836f\u9879\u76ee\u8fdb\u5c55<\/span><\/p>\n<\/p><\/div>\n<p>&ldquo; \u817e\u76db\u535a\u836f\u81f4\u529b\u4e8e\u89e3\u51b3\u5f53\u4eca\u793e\u4f1a\u9762\u4e34\u7684\u6700\u7d27\u8feb\u7684\u516c\u5171\u536b\u751f\u96be\u9898\uff0c\u901a\u8fc7\u52a0\u5feb\u65b0\u836f\u5f00\u53d1\u6765\u9884\u9632\u3001\u6cbb\u7597\u548c\u6cbb\u6108\u4e00\u7cfb\u5217\u4f20\u67d3\u75c5\uff0c\u5305\u62ec\u65b0\u51a0\u80ba\u708e\u3001\u6162\u6027\u4e59\u578b\u809d\u708e\u3001\u591a\u91cd\u8010\u836f\u9769\u5170\u6c0f\u9634\u6027\u83cc\u611f\u67d3\u4ee5\u53ca\u827e\u6ecb\u75c5\u7b49\uff0c&rdquo;\u817e\u76db\u535a\u836f\u9996\u5e2d\u6267\u884c\u5b98\u6d2a\u5fd7\u535a\u58eb\u8bf4\u3002&ldquo;\u4e16\u754c\u6025\u9700\u6cbb\u7597\u65b0\u51a0\u80ba\u708e\u7684\u65b0\u836f\uff0c\u4f46\u5bf9\u4e8e\u4f20\u67d3\u75c5\u65b0\u836f\u7684\u9700\u6c42\u8fdc\u8fdc\u8d85\u51fa\u5f53\u4eca\u7684\u65b0\u51a0\u80ba\u708e\u75ab\u60c5\u3002\u4f20\u67d3\u75c5\u53ef\u5bfc\u81f4\u6b7b\u4ea1\u548c\u6b8b\u75be\uff0c\u5e76\u5bf9\u793e\u4f1a\u548c\u7ecf\u6d4e\u5e26\u6765\u7834\u574f\u6027\u7684\u5f71\u54cd\uff0c\u8fd9\u662f\u6211\u4eec\u4e0d\u80fd\u5ffd\u89c6\u7684\u4e8b\u5b9e\u3002\u6211\u4eec\u5fc5\u987b\u4e3a\u4eca\u540e\u4e0d\u53ef\u907f\u514d\u7684\u516c\u5171\u536b\u751f\u6311\u6218\u505a\u597d\u51c6\u5907\u3002\u817e\u76db\u535a\u836f\u79ef\u6781\u5e94\u5bf9\u8fd9\u4e00\u6311\u6218\uff0c\u81f4\u529b\u4e8e\u6539\u5584\u4eba\u4eec\u7684\u5065\u5eb7\u72b6\u51b5\u548c\u751f\u6d3b\u8d28\u91cf\uff0c\u65e0\u8bba\u4ed6\u4eec\u8eab\u5728\u4f55\u5904\u3002&rdquo;<\/p>\n<p><strong>SARS-CoV-2\u9879\u76ee\u8fdb\u5c55<\/strong><\/p>\n<ul type=\"disc\">\n<li>BRII-196\u548cBRII-198\u4e3a\u975e\u7ade\u4e89\u6027\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2(SARS-CoV-2)\u4e2d\u548c\u6297\u4f53\uff0c\u5176\u4e2d\u7279\u522b\u5e94\u7528\u4e86\u57fa\u56e0\u5de5\u7a0b\u6280\u672f\u4ee5\u964d\u4f4e\u6297\u4f53\u4f9d\u8d56\u6027\u589e\u5f3a\u4f5c\u7528\u7684\u98ce\u9669\u3002\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2(SARS-CoV-2) \u611f\u67d3\u5bfc\u81f4\u65b0\u51a0\u80ba\u708e\uff08COVID-19\uff09\u3002\u817e\u76db\u535a\u836f\u6b63\u5728\u4e0e\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\uff08NIH\uff09\u4e0b\u5c5e\u7684\u56fd\u5bb6\u8fc7\u654f\u548c\u4f20\u67d3\u75c5\u7814\u7a76\u6240\uff08NIAID\uff09\u5408\u4f5c\uff0c\u8fdb\u884c\u6297\u4f53\u8054\u5408\u7528\u836f\u7597\u6cd5\u7684\u4e8c\/\u4e09\u671f\u4e34\u5e8a\u7814\u7a76\u3002\u8fd9\u9879\u7814\u7a76\u5c5e\u4e8eNIAID\u7684 ACTIV-3\u4e3b\u4e34\u5e8a\u65b9\u6848\u7684\u4e00\u90e8\u5206\uff0c\u5c06\u68c0\u9a8c\u5728\u6807\u51c6\u6cbb\u7597\u57fa\u7840\u4e0a\uff0cBRII-196\u548cBRII-198\u8054\u5408\u7597\u6cd5\u5728\u60a3\u6709\u66f4\u4e25\u91cd\u75be\u75c5\u7684\u4f4f\u9662\u75c5\u4eba\u4e2d\u7684\u4e34\u5e8a\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002\u8be5\u7814\u7a76(NCT04501978)\u4e8e2020\u5e7412\u6708\u5f00\u59cb\u7ed9\u836f\uff0c\u521d\u6b65\u7ed3\u679c\u6709\u671b\u5728\u660e\u5e74\u5e74\u521d\u83b7\u5f97\u3002\u4e00\u65e6\u83b7\u5f97\u6709\u6548\u7684\u4e34\u5e8a\u6570\u636e\uff0c\u817e\u76db\u535a\u836f\u5c06\u4e0e\u4e16\u754c\u5404\u56fd\u7684\u76d1\u7ba1\u673a\u6784\u7d27\u5bc6\u5408\u4f5c\uff0c\u786e\u4fdd\u5c06\u6570\u636e\u5c3d\u5feb\u63d0\u4ea4\u8fdb\u884c\u5ba1\u67e5\uff0c\u4ee5\u4fbf\u8ba9\u53ef\u80fd\u4ece\u8be5\u7597\u6cd5\u4e2d\u53d7\u76ca\u7684\u60a3\u8005\u7b2c\u4e00\u65f6\u95f4\u5f97\u5230\u6cbb\u7597\u3002\u540c\u65f6\uff0c\u4e3aBRII-196\u548cBRII-198\u7597\u6cd5\u5728\u9ad8\u5371\u975e\u4f4f\u9662\u60a3\u8005\u4e2d\u8fdb\u884c\u7814\u7a76\u7684\u51c6\u5907\u5de5\u4f5c\u4e5f\u8fdb\u5c55\u5230\u4e86\u6700\u7ec8\u9636\u6bb5\u3002<\/li>\n<li>\u817e\u76db\u535a\u836f\u8fd8\u4e8e2020\u5e7411\u6708\u5411\u9999\u6e2f\u7279\u522b\u884c\u653f\u533a\u653f\u5e9c\u536b\u751f\u7f72\u63d0\u4ea4\u4e86\u9488\u5bf9BRII-196\u548cBRII-198\u8054\u5408\u7528\u836f\u7684\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c\u5e76\u4e8e2020\u5e7412\u6708\u5411\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u7ba1\u7406\u5c40\u63d0\u4ea4\u4e86\u9488\u5bf9\u8be5\u7814\u7a76\u7684\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u3002\u8be5\u4e34\u5e8a\u8bd5\u9a8c\u5c06\u7814\u7a76\u8be5\u7597\u6cd5\u5728\u60a3\u6709\u65b0\u51a0\u80ba\u708e\u7684\u4e9a\u6d32\u4eba\u7fa4\u4e2d\u7684\u4e34\u5e8a\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\uff0c\u9884\u8ba1\u5c06\u4e8e2021\u5e74\u521d\u542f\u52a8\u3002<\/li>\n<\/ul>\n<p><strong>\u4e59\u578b\u809d\u708e\uff08HBV\uff09\u6cbb\u6108\u9879\u76ee\u8fdb\u5c55<\/strong><\/p>\n<ul type=\"disc\">\n<li><span class=\"xn-money\">1b<\/span>\/2a\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u4e2d\u671f\u6570\u636e\u65e8\u5728\u8bc4\u4f30BRII-179\uff08VBI-2601\uff09\uff08\u4e00\u79cd\u65b0\u578b\u91cd\u7ec4\u86cb\u767d\u514d\u75ab\u7597\u6cd5\uff09\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u6297\u75c5\u6bd2\u6d3b\u6027\uff0c\u5df2\u8bc1\u660e\u5176\u8bf1\u5bfc\u6162\u6027\u4e59\u809d\u60a3\u8005\u4e2d\u4ea7\u751f\u6297\u4f53\u548cT\u7ec6\u80de\u53cd\u5e94\u3002<\/li>\n<li>\u516c\u53f8\u5ba3\u5e03\u5df2\u5b8c\u6210BRII-835\uff08VIR-2218\uff092\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u62db\u52df\u5de5\u4f5c\uff0c\u8fd9\u662f\u4e00\u79cd\u65b0\u578b\u7684\u5728\u7814RNA\u5e72\u6270\u6cbb\u7597\u836f\u7269\uff08RNAi\uff09\uff0c\u65e8\u5728\u6291\u5236\u5305\u62ec\u4e59\u809d\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u7684\u8868\u8fbe\u5728\u5185\u7684\u6240\u6709\u4e59\u809d\u75c5\u6bd2\u86cb\u767d\u7684\u8868\u8fbe\u3002\u4e2d\u671f\u6570\u636e\u9884\u8ba1\u5c06\u4e8e2021\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u516c\u5e03\u3002<\/li>\n<li>\u57282021\u5e74\u7b2c\u4e00\u5b63\u5ea6\uff0c\u516c\u53f8\u8fd8\u51c6\u5907\u542f\u52a8\u4e00\u9879\u4e8c\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u8bc1\u660eBRII-179\u548cBRII-835\u8054\u5408\u7528\u836f\u5728\u6301\u7eed\u63a5\u53d7\u6838\u82f7\u9178\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002<\/li>\n<\/ul>\n<p><strong>\u591a\u836f\u8010\u836f\u9769\u5170\u6c0f\u9634\u6027\u7ec6\u83cc\u611f\u67d3\u9879\u76ee\u8fdb\u5c55<\/strong><\/p>\n<p>\u817e\u76db\u535a\u836f\u5c06\u4e0eQpex Biopharma\u516c\u53f8\u5408\u4f5c\uff0c\u5728\u4e2d\u56fd\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u4e00\u7cfb\u5217\u65b0\u578b\u6297\u751f\u7d20\u4ea7\u54c1\uff0c\u4ee5\u6cbb\u7597\u7531\u9ad8\u5ea6\u8010\u836f\u7684\u9769\u5170\u6c0f\u9634\u6027\u75c5\u539f\u4f53\u5f15\u8d77\u7684\u611f\u67d3\u3002<\/p>\n<ul type=\"disc\">\n<li>\u4e00\u79cd\u5168\u65b0\u8d85\u5e7f\u8c31&beta;-\u5185\u9170\u80fa\u9176\u6291\u5236\u5242BRII-636\uff08QPX-7728\uff09\u7684\u4e00\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e8e2020\u5e7411\u6708\u5728\u7f8e\u56fd\u83b7\u5f97\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u6279\u51c6\u5e76\u542f\u52a8\u3002\u8fd9\u9879\u4e00\u671f\u8bd5\u9a8c\u5c06\u7814\u7a76\u5728\u5065\u5eb7\u6210\u4eba\u53d7\u8bd5\u8005\u4e2d\u9996\u5148\u5355\u72ec\u4f7f\u7528BRII-636\u8fdb\u884c\u5355\u6b21\u548c\u591a\u6b21\u9759\u8109\u6ce8\u5c04\uff0c\u8fdb\u800c\u4e0e&beta;-\u5185\u9170\u80fa\u7c7b\u6297\u751f\u7d20\u8054\u5408\u4f7f\u7528\u7684\u5b89\u5168\u6027\u548c\u836f\u4ee3\u52a8\u529b\u5b66\u3002<\/li>\n<li>\u5373\u5c06\u5728\u7f8e\u56fd\u63d0\u4ea4BRII-672\u7684\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c\u8be5\u836f\u7269\u4e3a\u4e00\u79cd\u53e3\u670d\u8d85\u5e7f\u8c31&beta;-\u5185\u9170\u80fa\u9176\u6291\u5236\u5242\uff0c\u7528\u4e8e\u6cbb\u7597\u4ea7\u751f\u8d85\u5e7f\u8c31&beta;-\u5185\u9170\u80fa\u9176\uff08ESBL\uff09\u548c\u78b3\u9752\u9709\u70ef\u9176\u7684\u80a0\u6746\u83cc\uff0c\u4e00\u671f\u4e34\u5e8a\u7814\u7a76\u5c06\u4e8e2021\u5e743\u6708\u542f\u52a8\u3002<\/li>\n<li>\u5c06\u5728\u7f8e\u56fd\u63d0\u4ea4BRII-693\uff08QPX-9003\uff09\u7684\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c\u8be5\u836f\u7269\u4e3a\u65b0\u4e00\u4ee3\u5408\u6210\u591a\u7c98\u83cc\u7d20\uff0c\u7528\u4e8e\u6cbb\u7597\u7531\u94dc\u7eff\u5047\u5355\u80de\u83cc\u548c\u9c8d\u6c0f\u4e0d\u52a8\u6746\u83cc\u5f15\u8d77\u7684\u591a\u836f\u8010\u836f\u6027\u611f\u67d3\uff0c\u9884\u8ba1\u4e8e2021\u5e743\u6708\u542f\u52a8\u4e00\u671f\u4e34\u5e8a\u7814\u7a76\u3002<\/li>\n<\/ul>\n<p><strong>\u827e\u6ecb\u75c5\uff08HIV\uff09\u9879\u76ee\u8fdb\u5c55<\/strong><\/p>\n<ul type=\"disc\">\n<li>\u516c\u53f8\u5728\u4e3a\u827e\u6ecb\u75c5\u6bd2\u611f\u67d3\u8005\u5f00\u53d1\u4e00\u79cd\u5168\u65b0\u7684\u6cbb\u7597\u65b9\u6848\uff0c\u6bcf\u5468\u53e3\u670d\u4e00\u7247\u836f\uff0c\u5e76\u8ba1\u5212\u4e8e2021\u5e741\u6708\u5728\u7f8e\u56fd\u63d0\u4ea4BRII-778\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c\u8be5\u836f\u7269\u6709\u671b\u5b9e\u73b0\u6bcf\u5468\u53ea\u9700\u53e3\u670d\u4e00\u6b21\u3002<\/li>\n<li>\u516c\u53f8\u5f00\u53d1\u7684\u53e6\u4e00\u79cd\u6709\u671b\u5b9e\u73b0\u6bcf\u5468\u53e3\u670d\u4e00\u6b21\u7684\u5206\u5b50\u836f\u7269BRII-732\u4e5f\u8ba1\u5212\u4e8e2021\u5e741\u6708\u5728\u7f8e\u56fd\u63d0\u4ea4\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u3002<\/li>\n<li>BRII-778\u548cBRII-732\u7684\u4e00\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5747\u9884\u8ba1\u4e8e2021\u5e742\u6708\u542f\u52a8\u3002<\/li>\n<\/ul>\n<p><strong>\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\uff08CNS\uff09\u9879\u76ee\u8fdb\u5c55<\/strong><\/p>\n<ul type=\"disc\">\n<li>\u516c\u53f8\u5c06\u7ee7\u7eed\u63a8\u8fdb\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u7684\u9879\u76ee\uff0c\u91cd\u70b9\u6539\u5584\u5bf9\u60a3\u6709\u4e25\u91cd\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u800c<span id=\"spanHghltd2d6\">\u6ca1\u6709\u6709\u6548\u7597\u6cd5\u60a3\u8005\u7684\u6cbb\u7597<\/span>\u3002\u516c\u53f8\u8ba1\u5212\u4e8e2021\u5e741\u6708\u63d0\u4ea4BRII-296\u7684\u7f8e\u56fd\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c\u5e76\u9884\u8ba1\u4e8e2021\u5e743\u6708\u542f\u52a8\u4e00\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/li>\n<\/ul>\n<p><strong>\u7ba1\u7406\u5c42\u884c\u653f\u4efb\u547d<\/strong><\/p>\n<p>\u817e\u76db\u535a\u836f\u540c\u65f6\u5ba3\u5e03\u4e86\u51e0\u9879\u7ba1\u7406\u5c42\u4eba\u4e8b\u4efb\u547d\uff0c\u4ee5\u52a9\u529b\u516c\u53f8\u5728\u7f8e\u56fd\u7684\u6301\u7eed\u589e\u957f\u3002<\/p>\n<ul type=\"disc\">\n<li>David Margolis\u535a\u58eb\u52a0\u5165\u817e\u76db\u535a\u836f\u62c5\u4efb\u526f\u603b\u88c1\uff0c\u8d1f\u8d23\u516c\u53f8\u5728\u7f8e\u56fd\u7684\u4f20\u67d3\u75c5\u4e34\u5e8a\u9879\u76ee\u3002Margolis\u535a\u58eb\u4e5f\u5c06\u652f\u6301\u4e2d\u56fd\u7684\u4e34\u5e8a\u9879\u76ee\u5e76\u63d0\u4f9b\u6218\u7565\u5efa\u8bae\u3002\u52a0\u5165\u817e\u76db\u535a\u836f\u4e4b\u524dMargolis\u535a\u58eb\u5c31\u804c\u4e8eGSK\u548cViiV Healthcare\u516c\u53f8\u3002<\/li>\n<li>\u949f\u793c\u6770\u535a\u58eb\u4ece\u7f8e\u56fd\u5409\u5229\u5fb7\u516c\u53f8\u52a0\u5165\u817e\u76db\u535a\u836f\u62c5\u4efb\u526f\u603b\u88c1\uff0c\u8d1f\u8d23\u751f\u7269\u7edf\u8ba1\u3001\u6d41\u884c\u75c5\u5b66\u53ca\u771f\u5b9e\u4e16\u754c\u7814\u7a76\uff08RWE\uff09\u3002\u4ed6\u5c06\u5e26\u9886\u5404\u65b9\u56e2\u961f\u91c7\u7528\u786e\u5b9e\u6709\u6548\u7684\u65b9\u6cd5\u8bbe\u8ba1\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u6536\u96c6\u3001\u5206\u6790\u548c\u89e3\u8bfb\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\uff0c\u4ee5\u5b9e\u73b0\u65b0\u836f\u7684\u6279\u51c6\u548c\u4e0a\u5e02\u3002<\/li>\n<li>Lorraine Horgan\u5973\u58eb\u664b\u5347\u4e3a\u526f\u603b\u88c1\uff0c\u8d1f\u8d23\u9879\u76ee\u89c4\u5212\u4e0e\u7ba1\u7406\u3002Horgan\u5973\u58eb\u4e8e2019\u5e748\u6708\u52a0\u5165\u817e\u76db\u535a\u836f\uff0c\u8d1f\u8d23\u5efa\u7acb\u9879\u76ee\u7ba1\u7406\u90e8\u95e8\u3002\u5979\u5bf9\u4e8e\u4f20\u67d3\u75c5\u7b49\u591a\u4e2a\u6cbb\u7597\u9886\u57df\u548c\u591a\u79cd\u6cbb\u7597\u65b9\u6cd5\u90fd\u6709\u4e30\u5bcc\u7684\u7ecf\u9a8c\uff0c\u5e76\u5177\u5907\u5168\u9762\u548c\u7cfb\u7edf\u7684\u836f\u54c1\u5f00\u53d1\u7ecf\u9a8c\u3002<\/li>\n<li>\u9a6c\u9aa5\u535a\u58eb\u664b\u5347\u4e3a\u526f\u603b\u88c1\uff0c\u8d1f\u8d23\u4e34\u5e8a\u524d\u7814\u7a76\u548c\u5f00\u53d1\u3002\u9a6c\u535a\u58eb\u4e8e2019\u5e746\u6708\u52a0\u5165\u817e\u76db\u535a\u836f\uff0c\u5efa\u7acb\u4e86\u516c\u53f8\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u548c\u4e34\u5e8a\u836f\u7406\u5b66\u90e8\u95e8\uff0c\u5e76\u534f\u52a9\u5c06\u6240\u6709\u9879\u76ee\u4ece\u4e34\u5e8a\u524d\u9636\u6bb5\u63a8\u8fdb\u5230\u4e34\u5e8a\u9636\u6bb5\u3002\u4ed6\u5bf9\u591a\u79cd\u6cbb\u7597\u65b9\u6cd5\u62e5\u670920\u591a\u5e74\u7684\u836f\u7269\u53d1\u73b0\u548c\u5f00\u53d1\u7ecf\u9a8c\u3002<\/li>\n<\/ul>\n<p>\u76f8\u5173\u94fe\u63a5 :<\/p>\n<p>http:\/\/www.briibio.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e0e\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662(NIH)\u8fc7\u654f\u548c\u4f20\u67d3\u75c5\u7814\u7a76\u6240(NIAID)\u5408\u4f5c\u5f00\u5c55\u7814\u7a76\u6027\u5355\u514b\u9686\u6297\u4f53BRII-196\u548cBRII-198\u8054\u5408\u7528\u836f\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u7528\u4e8e\u6cbb\u7597\u65b0\u51a0\u80ba\u708e\uff08COVID-19\uff09 \u6301\u7eed\u5feb\u901f\u63a8\u8fdb\u5728\u7814\u65b0\u836f\u7684\u5f00\u53d1\u5de5\u4f5c\uff0c\u4ee5\u5bf9\u6297\u4e59\u578b\u809d\u708e\uff08HBV\uff09\u3001\u591a\u91cd\u8010\u836f\u9769\u5170\u6c0f\u9634\u6027\u83cc\u611f\u67d3\u4ee5\u53ca\u827e\u6ecb\u75c5\uff08HIV\uff09\u7b49\u4f20\u67d3\u75c5\u7684\u4e25\u91cd\u5a01\u80c1 \u9ad8\u6548\u63a8\u8fdb\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u9879\u76ee\uff0c\u8ba1\u5212\u4e8e2021\u5e741\u6708\u63d0\u4ea4BRII-296\u7684\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7 \u7f8e\u56fd\u9886\u5bfc\u56e2\u961f\u8fdb\u884c\u4eba\u4e8b\u4efb\u547d\u5e76\u8fdb\u4e00\u6b65\u58ee\u5927 \u5317\u4eac\u4e0e\u5317\u5361\u7f57\u6765\u7eb3\u5dde\u8fbe\u52d2\u59c6\u5e022020\u5e7412\u670818\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f42020\u5e7412\u670817\u65e5\uff0c\u817e\u76db\u535a\u836f\uff08Brii Biosciences\uff09\uff0c\u4e00\u5bb6\u6a2a\u8de8\u4e2d\u7f8e\uff0c\u81f4\u529b\u4e8e\u5f00\u53d1\u521b\u65b0\u836f\u7269\u4ee5\u670d\u52a1\u60a3\u8005\u9700\u6c42\uff0c\u5e76\u63d0\u5347\u5168\u7403\u548c\u4e2d\u56fd\u516c\u5171\u536b\u751f\u6c34\u5e73\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u4eca\u5929\u53d1\u5e03\u4e86\u516c\u53f8\u6700\u65b0\u7814\u53d1\u52a8\u6001\u3002\u516c\u53f8\u76846\u79cd\u6cbb\u7597\u5019\u9009\u836f\u7269\u5728\u7814\u53d1\u65b9\u9762\u53d6\u5f97\u4e86\u91cd\u5927\u8fdb\u5c55\uff0c\u8fd9\u4e9b\u836f\u7269\u7528\u4e8e\u5e94\u5bf9\u4e16\u754c\u4e0a\u6781\u5176\u4e25\u91cd\u7684\u4f20\u67d3\u75c5\u5a01\u80c1\uff0c\u5305\u62ec\u65b0\u51a0\u80ba\u708e\u3001\u4e59\u578b\u809d\u708e\u548c\u591a\u91cd\u8010\u836f\u9769\u5170\u6c0f\u9634\u6027\u83cc\u611f\u67d3\u7b49\u3002 \u817e\u76db\u535a\u836f\u9879\u76ee\u8fdb\u5c55 &ldquo; \u817e\u76db\u535a\u836f\u81f4\u529b\u4e8e\u89e3\u51b3\u5f53\u4eca\u793e\u4f1a\u9762\u4e34\u7684\u6700\u7d27\u8feb\u7684\u516c\u5171\u536b\u751f\u96be\u9898\uff0c\u901a\u8fc7\u52a0\u5feb\u65b0\u836f\u5f00\u53d1\u6765\u9884\u9632\u3001\u6cbb\u7597\u548c\u6cbb\u6108\u4e00\u7cfb\u5217\u4f20\u67d3\u75c5\uff0c\u5305\u62ec\u65b0\u51a0\u80ba\u708e\u3001\u6162\u6027\u4e59\u578b\u809d\u708e\u3001\u591a\u91cd\u8010\u836f\u9769\u5170\u6c0f\u9634\u6027\u83cc\u611f\u67d3\u4ee5\u53ca\u827e\u6ecb\u75c5\u7b49\uff0c&rdquo;\u817e\u76db\u535a\u836f\u9996\u5e2d\u6267\u884c\u5b98\u6d2a\u5fd7\u535a\u58eb\u8bf4\u3002&ldquo;\u4e16\u754c\u6025\u9700\u6cbb\u7597\u65b0\u51a0\u80ba\u708e\u7684\u65b0\u836f\uff0c\u4f46\u5bf9\u4e8e\u4f20\u67d3\u75c5\u65b0\u836f\u7684\u9700\u6c42\u8fdc\u8fdc\u8d85\u51fa\u5f53\u4eca\u7684\u65b0\u51a0\u80ba\u708e\u75ab\u60c5\u3002\u4f20\u67d3\u75c5\u53ef\u5bfc\u81f4\u6b7b\u4ea1\u548c\u6b8b\u75be\uff0c\u5e76\u5bf9\u793e\u4f1a\u548c\u7ecf\u6d4e\u5e26\u6765\u7834\u574f\u6027\u7684\u5f71\u54cd\uff0c\u8fd9\u662f\u6211\u4eec\u4e0d\u80fd\u5ffd\u89c6\u7684\u4e8b\u5b9e\u3002\u6211\u4eec\u5fc5\u987b\u4e3a\u4eca\u540e\u4e0d\u53ef\u907f\u514d\u7684\u516c\u5171\u536b\u751f\u6311\u6218\u505a\u597d\u51c6\u5907\u3002\u817e\u76db\u535a\u836f\u79ef\u6781\u5e94\u5bf9\u8fd9\u4e00\u6311\u6218\uff0c\u81f4\u529b\u4e8e\u6539\u5584\u4eba\u4eec\u7684\u5065\u5eb7\u72b6\u51b5\u548c\u751f\u6d3b\u8d28\u91cf\uff0c\u65e0\u8bba\u4ed6\u4eec\u8eab\u5728\u4f55\u5904\u3002&rdquo; SARS-CoV-2\u9879\u76ee\u8fdb\u5c55 BRII-196\u548cBRII-198\u4e3a\u975e\u7ade\u4e89\u6027\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2(SARS-CoV-2)\u4e2d\u548c\u6297\u4f53\uff0c\u5176\u4e2d\u7279\u522b\u5e94\u7528\u4e86\u57fa\u56e0\u5de5\u7a0b\u6280\u672f\u4ee5\u964d\u4f4e\u6297\u4f53\u4f9d\u8d56\u6027\u589e\u5f3a\u4f5c\u7528\u7684\u98ce\u9669\u3002\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2(SARS-CoV-2) \u611f\u67d3\u5bfc\u81f4\u65b0\u51a0\u80ba\u708e\uff08COVID-19\uff09\u3002\u817e\u76db\u535a\u836f\u6b63\u5728\u4e0e\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\uff08NIH\uff09\u4e0b\u5c5e\u7684\u56fd\u5bb6\u8fc7\u654f\u548c\u4f20\u67d3\u75c5\u7814\u7a76\u6240\uff08NIAID\uff09\u5408\u4f5c\uff0c\u8fdb\u884c\u6297\u4f53\u8054\u5408\u7528\u836f\u7597\u6cd5\u7684\u4e8c\/\u4e09\u671f\u4e34\u5e8a\u7814\u7a76\u3002\u8fd9\u9879\u7814\u7a76\u5c5e\u4e8eNIAID\u7684 ACTIV-3\u4e3b\u4e34\u5e8a\u65b9\u6848\u7684\u4e00\u90e8\u5206\uff0c\u5c06\u68c0\u9a8c\u5728\u6807\u51c6\u6cbb\u7597\u57fa\u7840\u4e0a\uff0cBRII-196\u548cBRII-198\u8054\u5408\u7597\u6cd5\u5728\u60a3\u6709\u66f4\u4e25\u91cd\u75be\u75c5\u7684\u4f4f\u9662\u75c5\u4eba\u4e2d\u7684\u4e34\u5e8a\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002\u8be5\u7814\u7a76(NCT04501978)\u4e8e2020\u5e7412\u6708\u5f00\u59cb\u7ed9\u836f\uff0c\u521d\u6b65\u7ed3\u679c\u6709\u671b\u5728\u660e\u5e74\u5e74\u521d\u83b7\u5f97\u3002\u4e00\u65e6\u83b7\u5f97\u6709\u6548\u7684\u4e34\u5e8a\u6570\u636e\uff0c\u817e\u76db\u535a\u836f\u5c06\u4e0e\u4e16\u754c\u5404\u56fd\u7684\u76d1\u7ba1\u673a\u6784\u7d27\u5bc6\u5408\u4f5c\uff0c\u786e\u4fdd\u5c06\u6570\u636e\u5c3d\u5feb\u63d0\u4ea4\u8fdb\u884c\u5ba1\u67e5\uff0c\u4ee5\u4fbf\u8ba9\u53ef\u80fd\u4ece\u8be5\u7597\u6cd5\u4e2d\u53d7\u76ca\u7684\u60a3\u8005\u7b2c\u4e00\u65f6\u95f4\u5f97\u5230\u6cbb\u7597\u3002\u540c\u65f6\uff0c\u4e3aBRII-196\u548cBRII-198\u7597\u6cd5\u5728\u9ad8\u5371\u975e\u4f4f\u9662\u60a3\u8005\u4e2d\u8fdb\u884c\u7814\u7a76\u7684\u51c6\u5907\u5de5\u4f5c\u4e5f\u8fdb\u5c55\u5230\u4e86\u6700\u7ec8\u9636\u6bb5\u3002 \u817e\u76db\u535a\u836f\u8fd8\u4e8e2020\u5e7411\u6708\u5411\u9999\u6e2f\u7279\u522b\u884c\u653f\u533a\u653f\u5e9c\u536b\u751f\u7f72\u63d0\u4ea4\u4e86\u9488\u5bf9BRII-196\u548cBRII-198\u8054\u5408\u7528\u836f\u7684\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c\u5e76\u4e8e2020\u5e7412\u6708\u5411\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u7ba1\u7406\u5c40\u63d0\u4ea4\u4e86\u9488\u5bf9\u8be5\u7814\u7a76\u7684\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u3002\u8be5\u4e34\u5e8a\u8bd5\u9a8c\u5c06\u7814\u7a76\u8be5\u7597\u6cd5\u5728\u60a3\u6709\u65b0\u51a0\u80ba\u708e\u7684\u4e9a\u6d32\u4eba\u7fa4\u4e2d\u7684\u4e34\u5e8a\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\uff0c\u9884\u8ba1\u5c06\u4e8e2021\u5e74\u521d\u542f\u52a8\u3002 \u4e59\u578b\u809d\u708e\uff08HBV\uff09\u6cbb\u6108\u9879\u76ee\u8fdb\u5c55 1b\/2a\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u4e2d\u671f\u6570\u636e\u65e8\u5728\u8bc4\u4f30BRII-179\uff08VBI-2601\uff09\uff08\u4e00\u79cd\u65b0\u578b\u91cd\u7ec4\u86cb\u767d\u514d\u75ab\u7597\u6cd5\uff09\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u6297\u75c5\u6bd2\u6d3b\u6027\uff0c\u5df2\u8bc1\u660e\u5176\u8bf1\u5bfc\u6162\u6027\u4e59\u809d\u60a3\u8005\u4e2d\u4ea7\u751f\u6297\u4f53\u548cT\u7ec6\u80de\u53cd\u5e94\u3002 \u516c\u53f8\u5ba3\u5e03\u5df2\u5b8c\u6210BRII-835\uff08VIR-2218\uff092\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u62db\u52df\u5de5\u4f5c\uff0c\u8fd9\u662f\u4e00\u79cd\u65b0\u578b\u7684\u5728\u7814RNA\u5e72\u6270\u6cbb\u7597\u836f\u7269\uff08RNAi\uff09\uff0c\u65e8\u5728\u6291\u5236\u5305\u62ec\u4e59\u809d\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u7684\u8868\u8fbe\u5728\u5185\u7684\u6240\u6709\u4e59\u809d\u75c5\u6bd2\u86cb\u767d\u7684\u8868\u8fbe\u3002\u4e2d\u671f\u6570\u636e\u9884\u8ba1\u5c06\u4e8e2021\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u516c\u5e03\u3002 \u57282021\u5e74\u7b2c\u4e00\u5b63\u5ea6\uff0c\u516c\u53f8\u8fd8\u51c6\u5907\u542f\u52a8\u4e00\u9879\u4e8c\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u8bc1\u660eBRII-179\u548cBRII-835\u8054\u5408\u7528\u836f\u5728\u6301\u7eed\u63a5\u53d7\u6838\u82f7\u9178\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002 \u591a\u836f\u8010\u836f\u9769\u5170\u6c0f\u9634\u6027\u7ec6\u83cc\u611f\u67d3\u9879\u76ee\u8fdb\u5c55 \u817e\u76db\u535a\u836f\u5c06\u4e0eQpex Biopharma\u516c\u53f8\u5408\u4f5c\uff0c\u5728\u4e2d\u56fd\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u4e00\u7cfb\u5217\u65b0\u578b\u6297\u751f\u7d20\u4ea7\u54c1\uff0c\u4ee5\u6cbb\u7597\u7531\u9ad8\u5ea6\u8010\u836f\u7684\u9769\u5170\u6c0f\u9634\u6027\u75c5\u539f\u4f53\u5f15\u8d77\u7684\u611f\u67d3\u3002 \u4e00\u79cd\u5168\u65b0\u8d85\u5e7f\u8c31&beta;-\u5185\u9170\u80fa\u9176\u6291\u5236\u5242BRII-636\uff08QPX-7728\uff09\u7684\u4e00\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e8e2020\u5e7411\u6708\u5728\u7f8e\u56fd\u83b7\u5f97\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u6279\u51c6\u5e76\u542f\u52a8\u3002\u8fd9\u9879\u4e00\u671f\u8bd5\u9a8c\u5c06\u7814\u7a76\u5728\u5065\u5eb7\u6210\u4eba\u53d7\u8bd5\u8005\u4e2d\u9996\u5148\u5355\u72ec\u4f7f\u7528BRII-636\u8fdb\u884c\u5355\u6b21\u548c\u591a\u6b21\u9759\u8109\u6ce8\u5c04\uff0c\u8fdb\u800c\u4e0e&beta;-\u5185\u9170\u80fa\u7c7b\u6297\u751f\u7d20\u8054\u5408\u4f7f\u7528\u7684\u5b89\u5168\u6027\u548c\u836f\u4ee3\u52a8\u529b\u5b66\u3002 \u5373\u5c06\u5728\u7f8e\u56fd\u63d0\u4ea4BRII-672\u7684\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c\u8be5\u836f\u7269\u4e3a\u4e00\u79cd\u53e3\u670d\u8d85\u5e7f\u8c31&beta;-\u5185\u9170\u80fa\u9176\u6291\u5236\u5242\uff0c\u7528\u4e8e\u6cbb\u7597\u4ea7\u751f\u8d85\u5e7f\u8c31&beta;-\u5185\u9170\u80fa\u9176\uff08ESBL\uff09\u548c\u78b3\u9752\u9709\u70ef\u9176\u7684\u80a0\u6746\u83cc\uff0c\u4e00\u671f\u4e34\u5e8a\u7814\u7a76\u5c06\u4e8e2021\u5e743\u6708\u542f\u52a8\u3002 \u5c06\u5728\u7f8e\u56fd\u63d0\u4ea4BRII-693\uff08QPX-9003\uff09\u7684\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c\u8be5\u836f\u7269\u4e3a\u65b0\u4e00\u4ee3\u5408\u6210\u591a\u7c98\u83cc\u7d20\uff0c\u7528\u4e8e\u6cbb\u7597\u7531\u94dc\u7eff\u5047\u5355\u80de\u83cc\u548c\u9c8d\u6c0f\u4e0d\u52a8\u6746\u83cc\u5f15\u8d77\u7684\u591a\u836f\u8010\u836f\u6027\u611f\u67d3\uff0c\u9884\u8ba1\u4e8e2021\u5e743\u6708\u542f\u52a8\u4e00\u671f\u4e34\u5e8a\u7814\u7a76\u3002 \u827e\u6ecb\u75c5\uff08HIV\uff09\u9879\u76ee\u8fdb\u5c55 \u516c\u53f8\u5728\u4e3a\u827e\u6ecb\u75c5\u6bd2\u611f\u67d3\u8005\u5f00\u53d1\u4e00\u79cd\u5168\u65b0\u7684\u6cbb\u7597\u65b9\u6848\uff0c\u6bcf\u5468\u53e3\u670d\u4e00\u7247\u836f\uff0c\u5e76\u8ba1\u5212\u4e8e2021\u5e741\u6708\u5728\u7f8e\u56fd\u63d0\u4ea4BRII-778\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c\u8be5\u836f\u7269\u6709\u671b\u5b9e\u73b0\u6bcf\u5468\u53ea\u9700\u53e3\u670d\u4e00\u6b21\u3002 \u516c\u53f8\u5f00\u53d1\u7684\u53e6\u4e00\u79cd\u6709\u671b\u5b9e\u73b0\u6bcf\u5468\u53e3\u670d\u4e00\u6b21\u7684\u5206\u5b50\u836f\u7269BRII-732\u4e5f\u8ba1\u5212\u4e8e2021\u5e741\u6708\u5728\u7f8e\u56fd\u63d0\u4ea4\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u3002 BRII-778\u548cBRII-732\u7684\u4e00\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5747\u9884\u8ba1\u4e8e2021\u5e742\u6708\u542f\u52a8\u3002 \u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\uff08CNS\uff09\u9879\u76ee\u8fdb\u5c55 \u516c\u53f8\u5c06\u7ee7\u7eed\u63a8\u8fdb\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u7684\u9879\u76ee\uff0c\u91cd\u70b9\u6539\u5584\u5bf9\u60a3\u6709\u4e25\u91cd\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u800c\u6ca1\u6709\u6709\u6548\u7597\u6cd5\u60a3\u8005\u7684\u6cbb\u7597\u3002\u516c\u53f8\u8ba1\u5212\u4e8e2021\u5e741\u6708\u63d0\u4ea4BRII-296\u7684\u7f8e\u56fd\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff0c\u5e76\u9884\u8ba1\u4e8e2021\u5e743\u6708\u542f\u52a8\u4e00\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002 \u7ba1\u7406\u5c42\u884c\u653f\u4efb\u547d \u817e\u76db\u535a\u836f\u540c\u65f6\u5ba3\u5e03\u4e86\u51e0\u9879\u7ba1\u7406\u5c42\u4eba\u4e8b\u4efb\u547d\uff0c\u4ee5\u52a9\u529b\u516c\u53f8\u5728\u7f8e\u56fd\u7684\u6301\u7eed\u589e\u957f\u3002 David Margolis\u535a\u58eb\u52a0\u5165\u817e\u76db\u535a\u836f\u62c5\u4efb\u526f\u603b\u88c1\uff0c\u8d1f\u8d23\u516c\u53f8\u5728\u7f8e\u56fd\u7684\u4f20\u67d3\u75c5\u4e34\u5e8a\u9879\u76ee\u3002Margolis\u535a\u58eb\u4e5f\u5c06\u652f\u6301\u4e2d\u56fd\u7684\u4e34\u5e8a\u9879\u76ee\u5e76\u63d0\u4f9b\u6218\u7565\u5efa\u8bae\u3002\u52a0\u5165\u817e\u76db\u535a\u836f\u4e4b\u524dMargolis\u535a\u58eb\u5c31\u804c\u4e8eGSK\u548cViiV Healthcare\u516c\u53f8\u3002 \u949f\u793c\u6770\u535a\u58eb\u4ece\u7f8e\u56fd\u5409\u5229\u5fb7\u516c\u53f8\u52a0\u5165\u817e\u76db\u535a\u836f\u62c5\u4efb\u526f\u603b\u88c1\uff0c\u8d1f\u8d23\u751f\u7269\u7edf\u8ba1\u3001\u6d41\u884c\u75c5\u5b66\u53ca\u771f\u5b9e\u4e16\u754c\u7814\u7a76\uff08RWE\uff09\u3002\u4ed6\u5c06\u5e26\u9886\u5404\u65b9\u56e2\u961f\u91c7\u7528\u786e\u5b9e\u6709\u6548\u7684\u65b9\u6cd5\u8bbe\u8ba1\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u6536\u96c6\u3001\u5206\u6790\u548c\u89e3\u8bfb\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\uff0c\u4ee5\u5b9e\u73b0\u65b0\u836f\u7684\u6279\u51c6\u548c\u4e0a\u5e02\u3002 Lorraine Horgan\u5973\u58eb\u664b\u5347\u4e3a\u526f\u603b\u88c1\uff0c\u8d1f\u8d23\u9879\u76ee\u89c4\u5212\u4e0e\u7ba1\u7406\u3002Horgan\u5973\u58eb\u4e8e2019\u5e748\u6708\u52a0\u5165\u817e\u76db\u535a\u836f\uff0c\u8d1f\u8d23\u5efa\u7acb\u9879\u76ee\u7ba1\u7406\u90e8\u95e8\u3002\u5979\u5bf9\u4e8e\u4f20\u67d3\u75c5\u7b49\u591a\u4e2a\u6cbb\u7597\u9886\u57df\u548c\u591a\u79cd\u6cbb\u7597\u65b9\u6cd5\u90fd\u6709\u4e30\u5bcc\u7684\u7ecf\u9a8c\uff0c\u5e76\u5177\u5907\u5168\u9762\u548c\u7cfb\u7edf\u7684\u836f\u54c1\u5f00\u53d1\u7ecf\u9a8c\u3002 \u9a6c\u9aa5\u535a\u58eb\u664b\u5347\u4e3a\u526f\u603b\u88c1\uff0c\u8d1f\u8d23\u4e34\u5e8a\u524d\u7814\u7a76\u548c\u5f00\u53d1\u3002\u9a6c\u535a\u58eb\u4e8e2019\u5e746\u6708\u52a0\u5165\u817e\u76db\u535a\u836f\uff0c\u5efa\u7acb\u4e86\u516c\u53f8\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u548c\u4e34\u5e8a\u836f\u7406\u5b66\u90e8\u95e8\uff0c\u5e76\u534f\u52a9\u5c06\u6240\u6709\u9879\u76ee\u4ece\u4e34\u5e8a\u524d\u9636\u6bb5\u63a8\u8fdb\u5230\u4e34\u5e8a\u9636\u6bb5\u3002\u4ed6\u5bf9\u591a\u79cd\u6cbb\u7597\u65b9\u6cd5\u62e5\u670920\u591a\u5e74\u7684\u836f\u7269\u53d1\u73b0\u548c\u5f00\u53d1\u7ecf\u9a8c\u3002 \u76f8\u5173\u94fe\u63a5 : http:\/\/www.briibio.com&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2020121810000014871\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":14876,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-14871","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/14871","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=14871"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/14871\/revisions"}],"predecessor-version":[{"id":14875,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/14871\/revisions\/14875"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/14876"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=14871"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=14871"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=14871"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}