{"id":14578,"date":"2020-12-16T17:56:00","date_gmt":"2020-12-16T10:56:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/2020121617560014578"},"modified":"2020-12-17T09:22:35","modified_gmt":"2020-12-17T01:22:35","slug":"%e8%be%89%e7%91%9e%e4%b8%ad%e5%9b%bd%e4%b8%8e%e5%9f%ba%e7%9f%b3%e8%8d%af%e4%b8%9a%e5%88%9b%e6%96%b0%e5%90%88%e4%bd%9c%e8%87%b4%e5%8a%9b%e6%bb%a1%e8%b6%b3%e4%b8%ad%e5%9b%bd%e8%82%bf%e7%98%a4%e6%b2%bb","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/2020121617560014578","title":{"rendered":"\u8f89\u745e\u4e2d\u56fd\u4e0e\u57fa\u77f3\u836f\u4e1a\u521b\u65b0\u5408\u4f5c\u81f4\u529b\u6ee1\u8db3\u4e2d\u56fd\u80bf\u7624\u6cbb\u7597\u9886\u57df\u9700\u6c42"},"content":{"rendered":"<p><p>\u4e0a\u6d772020\u5e7412\u670816\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 12\u670816\u65e5\uff0c\u8f89\u745e\u4e2d\u56fd\u548c\u57fa\u77f3\u836f\u4e1a\u5728\u4e0a\u6d77\u4e3e\u884c\u6218\u7565\u5408\u4f5c\u542f\u52a8\u4eea\u5f0f\u3002\u6b64\u6b21\u4eea\u5f0f\u4ee5\u201c\u643a\u624b\u540c\u884c\uff0c\u5171\u521b\u5065\u5eb7\u4e2d\u56fd\u201d\u4e3a\u4e3b\u9898\uff0c\u52a0\u901f\u63a8\u8fdb\u5408\u4f5c\u9879\u76ee\u843d\u5730\uff0c\u53cc\u65b9\u540c\u65f6\u5ba3\u5e03\u6210\u7acb\u534f\u4f5c\u5c0f\u7ec4\uff0c\u643a\u624b\u5e76\u8fdb\uff0c\u6ee1\u8db3\u4e2d\u56fd\u80bf\u7624\u60a3\u8005\u672a\u88ab\u6ee1\u8db3\u7684\u9700\u6c42\u3002\u8fd9\u662f\u7ee7\u4eca\u5e749\u670830\u65e5\u53cc\u65b9\u8fbe\u6210\u6218\u7565\u5408\u4f5c\u5173\u7cfb\u540e\uff0c\u52a0\u901f\u9879\u76ee\u63a8\u8fdb\u7684\u91cd\u8981\u4e00\u73af\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder3698\">\n<p><a href=\"https:\/\/mma.prnasia.com\/media2\/1387115\/image_1.html\" target=\"_blank\" rel=\"nofollow noopener noreferrer\"><img decoding=\"async\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/image_1-269.jpg\" title=\"\u8f89\u745e\u751f\u7269\u5236\u836f\u96c6\u56e2\u4e0e\u57fa\u77f3\u836f\u4e1a\u6218\u7565\u5408\u4f5c\u5e86\u5178\" alt=\"\u8f89\u745e\u751f\u7269\u5236\u836f\u96c6\u56e2\u4e0e\u57fa\u77f3\u836f\u4e1a\u6218\u7565\u5408\u4f5c\u5e86\u5178\" \/><\/a><br \/><span>\u8f89\u745e\u751f\u7269\u5236\u836f\u96c6\u56e2\u4e0e\u57fa\u77f3\u836f\u4e1a\u6218\u7565\u5408\u4f5c\u5e86\u5178<\/span><\/p>\n<\/p><\/div>\n<p>\u8212\u683c\u5229\u5355\u6297\uff08CS1001\uff09\u662f\u57fa\u77f3\u836f\u4e1a\u5f00\u53d1\u7684\u4e00\u6b3e\u6f5c\u5728\u540c\u7c7b\u6700\u4f18PD-L1\u6297\u4f53\u836f\u7269\uff0c\u5176\u6f5c\u5728\u9002\u5e94\u75c7\u6db5\u76d6\u80ba\u764c\u3001\u80c3\u764c\u548c\u98df\u7ba1\u764c\u7b49\u591a\u4e2a\u4e2d\u56fd\u9ad8\u53d1\u764c\u75c7\u7c7b\u578b<span id=\"spanHghltad52\">\u3002<sup><sup>[1]<\/sup><\/sup><\/span>\u8f89\u745e\u83b7\u5f97\u57fa\u77f3\u836f\u4e1a\u7684\u6388\u6743\uff0c\u5728\u4e2d\u56fd\u72ec\u5bb6\u8d1f\u8d23\u8212\u683c\u5229\u5355\u6297\u7684\u5546\u4e1a\u5316\u7ecf\u8425\uff0c\u5e76\u5c06\u53d1\u6325\u5176\u884c\u4e1a\u9886\u5148\u7684\u5546\u4e1a\u5316\u80fd\u529b\uff0c\u8ba9\u8be5\u521b\u65b0\u7597\u6cd5\u66f4\u5feb\u60e0\u53ca\u4e2d\u56fd\u66f4\u5e7f\u5927\u5730\u533a\u7684\u533b\u751f\u548c\u60a3\u8005\u3002\u8be5\u4ea7\u54c1\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff08NDA\uff09\u4e8e\u4eca\u5e7411\u670812\u65e5\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u53d7\u7406\uff0c\u7528\u4e8e\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u665a\u671f\u9cde\u72b6\u548c\u975e\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u3002<\/p>\n<p>\u201c\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u8212\u683c\u5229\u5355\u6297\u5177\u6709\u826f\u597d\u7684\u5b89\u5168\u6027\uff0c\u5bf9\u665a\u671f\u9cde\u72b6\u548c\u975e\u9cde\u72b6NSCLC\u60a3\u8005\u5747\u6709\u826f\u597d\u4e34\u5e8a\u83b7\u76ca\uff0c\u80fd\u591f\u663e\u8457\u5ef6\u957f\u60a3\u8005\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff0c\u964d\u4f4e\u75be\u75c5\u8fdb\u5c55\u6216\u6b7b\u4ea1\u98ce\u9669\u3002\u8212\u683c\u5229\u5355\u6297\u672a\u6765\u5c06\u4e3a\u56fd\u5185\u4e34\u5e8a\u533b\u751f\u63d0\u4f9b\u65b0\u7684\u6cbb\u7597\u9009\u62e9\uff0c\u6ee1\u8db3\u56fd\u5185NSCLC\u60a3\u8005\u5c1a\u672a\u88ab\u6ee1\u8db3\u7684\u5de8\u5927\u4e34\u5e8a\u9700\u6c42\uff0c\u8ba9\u66f4\u591a\u60a3\u8005\u4ece\u4e2d\u83b7\u76ca\uff0c\u4e3a\u60a3\u8005\u5e26\u6765\u5ef6\u957f\u751f\u547d\u7684\u5e0c\u671b\uff0c\u5e76\u5e26\u6765\u6cbb\u7597\u4e0a\u7684\u7a81\u7834\u3002\u201d \u4e0a\u6d77\u5e02\u80ba\u79d1\u533b\u9662\u80bf\u7624\u79d1\u4e3b\u4efb\u5468\u5f69\u5b58\u6559\u6388\u8868\u793a\u3002<\/p>\n<p><span id=\"spanHghlt575d\">\u201c\u2018<\/span>\u4e3a\u60a3\u8005\u5e26\u6765\u6539\u53d8\u5176\u751f\u6d3b\u7684\u7a81\u7834\u521b\u65b0\u2019\u662f\u8f89\u745e\u4e00\u8d2f\u7684\u7406\u5ff5\uff0c\u6211\u4eec\u575a\u6301\u4ee5\u60a3\u8005\u4e3a\u4e2d\u5fc3\uff0c\u4e0d\u65ad\u5c06\u5168\u7403\u521b\u65b0\u836f\u7269\u548c\u7597\u6cd5\u5f15\u5165\u4e2d\u56fd\u3002\u5728\u4e2d\u56fd\u653f\u5e9c\u9f13\u52b1\u521b\u65b0\u4e0e\u52a0\u901f\u5ba1\u8bc4\u5ba1\u6279\u7684\u65b0\u5f62\u52bf\u4e0b\uff0c\u8f89\u745e\u79ef\u6781\u63a2\u7d22\u5e76\u4e0d\u65ad\u6269\u5927\u4e0e\u56fd\u5185\u521b\u65b0\u751f\u7269\u5236\u836f\u4f01\u4e1a\u7684\u5408\u4f5c\uff0c\u901a\u8fc7\u5185\u5916\u517c\u4fee\u7684\u65b9\u5f0f\uff0c\u9020\u798f\u56fd\u5185\u5e7f\u5927\u60a3\u8005\u3002<span id=\"spanHghltc415\">\u201d<\/span>\u8f89\u745e\u751f\u7269\u5236\u836f\u96c6\u56e2\u4e2d\u56fd\u533a\u9996\u5e2d\u8fd0\u8425\u5b98\u5434\u7428\u8bf4\u5230\uff0c\u201c\u6b64\u6b21\u542f\u52a8\u4f1a\u6807\u5fd7\u7740\u8f89\u745e\u4e0e\u57fa\u77f3\u6218\u7565\u5408\u4f5c\u7684\u771f\u6b63\u843d\u5730\uff0c\u53cc\u65b9\u5c06\u5728\u5408\u4f5c\u4e2d\u4e92\u76f8\u52a9\u529b\uff0c\u52a0\u901f\u4f18\u79c0\u80bf\u7624\u514d\u75ab\u836f\u7269\u7684\u4e0a\u5e02\u548c\u5546\u4e1a\u5316\uff0c\u8ba9\u60a3\u8005\u66f4\u5feb\u83b7\u5f97\u521b\u65b0\u6cbb\u7597\u836f\u7269\uff0c\u63a8\u52a8\u2018\u5065\u5eb7\u4e2d\u56fd2030\u2019\u76ee\u6807\u7684\u8fbe\u6210\u3002\u201d<\/p>\n<p>\u57fa\u77f3\u836f\u4e1a\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u6c5f\u5b81\u519b\u535a\u58eb\u8868\u793a\uff1a\u201c\u8f89\u745e\u548c\u57fa\u77f3\u836f\u4e1a\u6210\u4e3a\u6218\u7565\u5408\u4f5c\u4f19\u4f34\uff0c\u4f53\u73b0\u4e86\u53cc\u65b9\u7684\u76f8\u4e92\u4fe1\u4efb\u4e0e\u8ba4\u53ef\u3002\u764c\u75c7\u5728\u4e2d\u56fd\u5b58\u5728\u5de8\u5927\u7684\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u9700\u8981\u591a\u65b9\u643a\u624b\u5171\u8fdb\uff0c\u6b64\u6b21\u57fa\u77f3\u836f\u4e1a\u548c\u8f89\u745e\u7684\u6218\u7565\u5408\u4f5c\u5c06\u8fdb\u4e00\u6b65\u52a9\u529b\u53cc\u65b9\u7684\u5546\u4e1a\u5316\u5e03\u5c40\u548c\u4ea7\u54c1\u7ba1\u7ebf\u5e03\u5c40\uff0c\u529b\u4e89\u5c06\u66f4\u591a\u7684\u521b\u65b0\u80bf\u7624\u6cbb\u7597\u4ea7\u54c1\u5e26\u7ed9\u5e7f\u5927\u4e2d\u56fd\u60a3\u8005\u3002\u201d<\/p>\n<p><b>\u5173\u4e8e\u8212\u683c\u5229\u5355\u6297<\/b><\/p>\n<p>\u8212\u683c\u5229\u5355\u6297\u662f\u7531\u57fa\u77f3\u836f\u4e1a\u5f00\u53d1\u7684\u5728\u7814\u6297PD-L1\u5355\u514b\u9686\u6297\u4f53\u3002\u8212\u683c\u5229\u5355\u6297\u7684\u5f00\u53d1\u57fa\u4e8e\u7531\u7f8e\u56fdLigand\u516c\u53f8\u6388\u6743\u5f15\u8fdb\u7684OmniRat<sup>&reg;<\/sup>\u8f6c\u57fa\u56e0\u52a8\u7269\u5e73\u53f0\u3002\u8be5\u5e73\u53f0\u53ef\u4e00\u7ad9\u5f0f\u4ea7\u751f\u5168\u4eba\u6e90\u6297\u4f53\u3002\u4f5c\u4e3a\u4e00\u79cd\u5168\u4eba\u6e90\u5168\u957f\u6297PD-L1\u5355\u514b\u9686\u6297\u4f53\uff0c\u8212\u683c\u5229\u5355\u6297\u662f\u4e00\u79cd\u6700\u63a5\u8fd1\u4eba\u4f53\u7684\u5929\u7136G\u578b\u514d\u75ab\u7403\u86cb\u767d4\uff08IgG4\uff09\u5355\u6297\u836f\u7269\u3002\u8212\u683c\u5229\u5355\u6297\u5728\u60a3\u8005\u4f53\u5185\u4ea7\u751f\u514d\u75ab\u539f\u6027\u53ca\u76f8\u5173\u6bd2\u6027\u7684\u98ce\u9669\u66f4\u4f4e\uff0c\u8fd9\u4f7f\u5f97\u8212\u683c\u5229\u5355\u6297\u4e0e\u540c\u7c7b\u836f\u7269\u76f8\u6bd4\u4f53\u73b0\u51fa\u6f5c\u5728\u7684\u72ec\u7279\u4f18\u52bf\u3002<\/p>\n<p>\u8212\u683c\u5229\u5355\u6297\u5df2\u5728\u4e2d\u56fd\u5b8c\u6210I\u671f\u4e34\u5e8a\u7814\u7a76\u5242\u91cf\u722c\u5761\u3002\u5728Ia\u671f\u548cIb\u671f\u7814\u7a76\u4e2d\uff0c\u8212\u683c\u5229\u5355\u6297\u5728\u591a\u4e2a\u9002\u5e94\u8bc1\u4e2d\u5747\u8868\u73b0\u51fa\u826f\u597d\u7684\u6297\u80bf\u7624\u6d3b\u6027\u548c\u8010\u53d7\u6027\u3002<\/p>\n<p>\u76ee\u524d\uff0c\u8212\u683c\u5229\u5355\u6297\u6b63\u5728\u8fdb\u884c\u591a\u9879\u4e34\u5e8a\u7814\u7a76\uff0c\u9664\u4e86\u4e00\u9879\u7f8e\u56fd\u6865\u63a5\u6027I\u671f\u7814\u7a76\u5916\uff0c\u5728\u4e2d\u56fd\uff0c\u8212\u683c\u5229\u5355\u6297\u6b63\u9488\u5bf9\u591a\u4e2a\u764c\u79cd\u5f00\u5c55\u4e00\u9879\u591a\u81c2Ib\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u4e00\u9879\u9488\u5bf9\u6dcb\u5df4\u7624\u7684II\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76\uff0c\u4ee5\u53ca\u56db\u9879\u5206\u522b\u5728III\u3001IV\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u80c3\u764c\u548c\u98df\u7ba1\u764c\u7684III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76\u3002\u5176\u4e2d\u8212\u683c\u5229\u5355\u6297\u6cbb\u7597IV\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u7684III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u8fbe\u5230\u4e3b\u8981\u7ec8\u70b9\uff0cNDA\u5df2\u7ecf\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u53d7\u7406\u3002<\/p>\n<p><b>\u5173\u4e8e\u8f89\u745e<\/b><\/p>\n<p>\u5728\u8f89\u745e\uff0c\u6211\u4eec\u81f4\u529b\u4e8e\u8fd0\u7528\u79d1\u5b66\u4ee5\u53ca\u6211\u4eec\u7684\u5168\u7403\u8d44\u6e90\u6765\u63d0\u4f9b\u80fd\u5ef6\u957f\u5e76\u660e\u663e\u6539\u5584\u4eba\u7c7b\u5bff\u547d\u7684\u6cbb\u7597\u3002\u5728\u533b\u7597\u536b\u751f\u4ea7\u54c1\uff08\u5305\u62ec\u521b\u65b0\u836f\u548c\u75ab\u82d7\uff09\u7684\u63a2\u7d22\u3001\u7814\u53d1\u548c\u751f\u4ea7\u8fc7\u7a0b\u4e2d\uff0c\u6211\u4eec\u5747\u5efa\u7acb\u4e86\u8d28\u91cf\u3001\u5b89\u5168\u548c\u4ef7\u503c\u6807\u51c6\u3002\u6bcf\u5929\uff0c\u53d1\u8fbe\u548c\u65b0\u5174\u5e02\u573a\u7684\u8f89\u745e\u5458\u5de5\u90fd\u81f4\u529b\u4e8e\u63a8\u8fdb\u5065\u5eb7\uff0c\u4ee5\u53ca\u80fd\u591f\u5e94\u5bf9\u6211\u4eec\u8fd9\u4e2a\u65f6\u4ee3\u6700\u4e3a\u68d8\u624b\u7684\u75be\u75c5\u7684\u9884\u9632\u548c\u6cbb\u7597\u65b9\u6848\u3002\u8f89\u745e\u8fd8\u4e0e\u4e16\u754c\u5404\u5730\u7684\u533b\u7597\u536b\u751f\u4e13\u4e1a\u4eba\u58eb\u3001\u653f\u5e9c\u548c\u793e\u533a\u5408\u4f5c\uff0c\u652f\u6301\u4e16\u754c\u5404\u5730\u7684\u4eba\u4eec\u80fd\u591f\u83b7\u5f97\u66f4\u4e3a\u53ef\u9760\u548c\u53ef\u627f\u4ed8\u7684\u533b\u7597\u536b\u751f\u670d\u52a1\u3002\u8fd9\u4e0e\u8f89\u745e\u4f5c\u4e3a\u4e00\u5bb6\u5353\u8d8a\u7684\u521b\u65b0\u751f\u7269\u5236\u836f\u516c\u53f8\u7684\u8d23\u4efb\u662f\u4e00\u81f4\u7684\u3002170\u591a\u5e74\u6765\uff0c\u8f89\u745e\u4e00\u76f4\u52aa\u529b\u4e3a\u4eba\u4eec\u63d0\u4f9b\u66f4\u597d\u3001\u66f4\u4f18\u8d28\u7684\u670d\u52a1\u3002\u5982\u9700\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u767b\u5f55 <a target=\"_blank\" href=\"http:\/\/www.pfizer.com\/\" rel=\"nofollow noopener noreferrer\">www.pfizer.com.cn<\/a>\u3002<\/p>\n<p><b>\u5173\u4e8e\u57fa\u77f3\u836f\u4e1a<\/b><\/p>\n<p>\u57fa\u77f3\u836f\u4e1a\u662f\u4e00\u5bb6\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u521b\u65b0\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u53ca\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\uff0c\u4ee5\u6ee1\u8db3\u4e2d\u56fd\u548c\u5168\u7403\u764c\u75c7\u60a3\u8005\u7684\u6bb7\u5207\u533b\u7597\u9700\u6c42\u3002\u6210\u7acb\u4e8e2015\u5e74\u5e95\uff0c\u57fa\u77f3\u836f\u4e1a\u5df2\u96c6\u7ed3\u4e86\u4e00\u652f\u5728\u65b0\u836f\u7814\u53d1\u3001\u4e34\u5e8a\u7814\u7a76\u4ee5\u53ca\u5546\u4e1a\u5316\u65b9\u9762\u62e5\u6709\u4e30\u5bcc\u7ecf\u9a8c\u7684\u4e16\u754c\u7ea7\u7ba1\u7406\u56e2\u961f\u3002\u516c\u53f8\u4ee5\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u8054\u5408\u7597\u6cd5\u4e3a\u6838\u5fc3\uff0c\u5efa\u7acb\u4e86\u4e00\u676116\u79cd\u80bf\u7624\u5019\u9009\u836f\u7269\u7ec4\u6210\u7684\u4e30\u5bcc\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u5176\u4e2d5\u6b3e\u540e\u671f\u5019\u9009\u836f\u7269\u6b63\u5904\u4e8e\u5173\u952e\u6027\u4e34\u5e8a\u8bd5\u9a8c\u6216\u6ce8\u518c\u9636\u6bb5\u3002\u51ed\u501f\u7ecf\u9a8c\u4e30\u5bcc\u7684\u7ba1\u7406\u56e2\u961f\u3001\u4e30\u5bcc\u7684\u7ba1\u7ebf\u3001\u4e13\u6ce8\u4e8e\u4e34\u5e8a\u5f00\u53d1\u7684\u4e1a\u52a1\u6a21\u5f0f\u548c\u5145\u88d5\u8d44\u91d1\uff0c\u57fa\u77f3\u836f\u4e1a\u7684\u613f\u666f\u662f\u6210\u4e3a\u4eab\u8a89\u5168\u7403\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u5f15\u9886\u653b\u514b\u764c\u75c7\u4e4b\u8def\u3002\u5982\u9700\u4e86\u89e3\u6709\u5173\u57fa\u77f3\u836f\u4e1a\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1a<a target=\"_blank\" href=\"http:\/\/www.cstonepharma.com\/\" rel=\"nofollow noopener noreferrer\">www.cstonepharma.com<\/a>\u3002<\/p>\n<div>\n<table id=\"convertedTable51c4\" cellspacing=\"0\" cellpadding=\"0\" border=\"1\" class=\"prntblns\">\n<tbody>\n<tr>\n<td class=\"prnsbt1 prnsbr1 prnvab prnsbb1 prnpl6 prnsbl1 prnpr6\">\n<p class=\"prnews_p\"><span class=\"prnews_span\">[1] 2019\u5e74\u5168\u56fd\u764c\u75c7\u62a5\u544a\uff0c\u4e2d\u534e\u4eba\u6c11\u5171\u548c\u56fd\u56fd\u5bb6\u536b\u751f\u5065\u5eb7\u59d4\u5458\u4f1a\u56fd\u5bb6\u80bf\u7624\u8d28\u63a7\u4e2d\u5fc3<br \/><a target=\"_blank\" href=\"http:\/\/www.china-rt.cn\/special\/846.html\" class=\"prnews_a\" rel=\"nofollow noopener noreferrer\">http:\/\/www.china-rt.cn\/special\/846.html<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>&nbsp;<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder0\">  <\/div>\n<p>\u76f8\u5173\u94fe\u63a5 :<\/p>\n<p>http:\/\/www.pfizer.com.cn<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e0a\u6d772020\u5e7412\u670816\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 12\u670816\u65e5\uff0c\u8f89\u745e\u4e2d\u56fd\u548c\u57fa\u77f3\u836f\u4e1a\u5728\u4e0a\u6d77\u4e3e\u884c\u6218\u7565\u5408\u4f5c\u542f\u52a8\u4eea\u5f0f\u3002\u6b64\u6b21\u4eea\u5f0f\u4ee5\u201c\u643a\u624b\u540c\u884c\uff0c\u5171\u521b\u5065\u5eb7\u4e2d\u56fd\u201d\u4e3a\u4e3b\u9898\uff0c\u52a0\u901f\u63a8\u8fdb\u5408\u4f5c\u9879\u76ee\u843d\u5730\uff0c\u53cc\u65b9\u540c\u65f6\u5ba3\u5e03\u6210\u7acb\u534f\u4f5c\u5c0f\u7ec4\uff0c\u643a\u624b\u5e76\u8fdb\uff0c\u6ee1\u8db3\u4e2d\u56fd\u80bf\u7624\u60a3\u8005\u672a\u88ab\u6ee1\u8db3\u7684\u9700\u6c42\u3002\u8fd9\u662f\u7ee7\u4eca\u5e749\u670830\u65e5\u53cc\u65b9\u8fbe\u6210\u6218\u7565\u5408\u4f5c\u5173\u7cfb\u540e\uff0c\u52a0\u901f\u9879\u76ee\u63a8\u8fdb\u7684\u91cd\u8981\u4e00\u73af\u3002 \u8f89\u745e\u751f\u7269\u5236\u836f\u96c6\u56e2\u4e0e\u57fa\u77f3\u836f\u4e1a\u6218\u7565\u5408\u4f5c\u5e86\u5178 \u8212\u683c\u5229\u5355\u6297\uff08CS1001\uff09\u662f\u57fa\u77f3\u836f\u4e1a\u5f00\u53d1\u7684\u4e00\u6b3e\u6f5c\u5728\u540c\u7c7b\u6700\u4f18PD-L1\u6297\u4f53\u836f\u7269\uff0c\u5176\u6f5c\u5728\u9002\u5e94\u75c7\u6db5\u76d6\u80ba\u764c\u3001\u80c3\u764c\u548c\u98df\u7ba1\u764c\u7b49\u591a\u4e2a\u4e2d\u56fd\u9ad8\u53d1\u764c\u75c7\u7c7b\u578b\u3002[1]\u8f89\u745e\u83b7\u5f97\u57fa\u77f3\u836f\u4e1a\u7684\u6388\u6743\uff0c\u5728\u4e2d\u56fd\u72ec\u5bb6\u8d1f\u8d23\u8212\u683c\u5229\u5355\u6297\u7684\u5546\u4e1a\u5316\u7ecf\u8425\uff0c\u5e76\u5c06\u53d1\u6325\u5176\u884c\u4e1a\u9886\u5148\u7684\u5546\u4e1a\u5316\u80fd\u529b\uff0c\u8ba9\u8be5\u521b\u65b0\u7597\u6cd5\u66f4\u5feb\u60e0\u53ca\u4e2d\u56fd\u66f4\u5e7f\u5927\u5730\u533a\u7684\u533b\u751f\u548c\u60a3\u8005\u3002\u8be5\u4ea7\u54c1\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\uff08NDA\uff09\u4e8e\u4eca\u5e7411\u670812\u65e5\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u53d7\u7406\uff0c\u7528\u4e8e\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u665a\u671f\u9cde\u72b6\u548c\u975e\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u3002 \u201c\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u8212\u683c\u5229\u5355\u6297\u5177\u6709\u826f\u597d\u7684\u5b89\u5168\u6027\uff0c\u5bf9\u665a\u671f\u9cde\u72b6\u548c\u975e\u9cde\u72b6NSCLC\u60a3\u8005\u5747\u6709\u826f\u597d\u4e34\u5e8a\u83b7\u76ca\uff0c\u80fd\u591f\u663e\u8457\u5ef6\u957f\u60a3\u8005\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff0c\u964d\u4f4e\u75be\u75c5\u8fdb\u5c55\u6216\u6b7b\u4ea1\u98ce\u9669\u3002\u8212\u683c\u5229\u5355\u6297\u672a\u6765\u5c06\u4e3a\u56fd\u5185\u4e34\u5e8a\u533b\u751f\u63d0\u4f9b\u65b0\u7684\u6cbb\u7597\u9009\u62e9\uff0c\u6ee1\u8db3\u56fd\u5185NSCLC\u60a3\u8005\u5c1a\u672a\u88ab\u6ee1\u8db3\u7684\u5de8\u5927\u4e34\u5e8a\u9700\u6c42\uff0c\u8ba9\u66f4\u591a\u60a3\u8005\u4ece\u4e2d\u83b7\u76ca\uff0c\u4e3a\u60a3\u8005\u5e26\u6765\u5ef6\u957f\u751f\u547d\u7684\u5e0c\u671b\uff0c\u5e76\u5e26\u6765\u6cbb\u7597\u4e0a\u7684\u7a81\u7834\u3002\u201d \u4e0a\u6d77\u5e02\u80ba\u79d1\u533b\u9662\u80bf\u7624\u79d1\u4e3b\u4efb\u5468\u5f69\u5b58\u6559\u6388\u8868\u793a\u3002 \u201c\u2018\u4e3a\u60a3\u8005\u5e26\u6765\u6539\u53d8\u5176\u751f\u6d3b\u7684\u7a81\u7834\u521b\u65b0\u2019\u662f\u8f89\u745e\u4e00\u8d2f\u7684\u7406\u5ff5\uff0c\u6211\u4eec\u575a\u6301\u4ee5\u60a3\u8005\u4e3a\u4e2d\u5fc3\uff0c\u4e0d\u65ad\u5c06\u5168\u7403\u521b\u65b0\u836f\u7269\u548c\u7597\u6cd5\u5f15\u5165\u4e2d\u56fd\u3002\u5728\u4e2d\u56fd\u653f\u5e9c\u9f13\u52b1\u521b\u65b0\u4e0e\u52a0\u901f\u5ba1\u8bc4\u5ba1\u6279\u7684\u65b0\u5f62\u52bf\u4e0b\uff0c\u8f89\u745e\u79ef\u6781\u63a2\u7d22\u5e76\u4e0d\u65ad\u6269\u5927\u4e0e\u56fd\u5185\u521b\u65b0\u751f\u7269\u5236\u836f\u4f01\u4e1a\u7684\u5408\u4f5c\uff0c\u901a\u8fc7\u5185\u5916\u517c\u4fee\u7684\u65b9\u5f0f\uff0c\u9020\u798f\u56fd\u5185\u5e7f\u5927\u60a3\u8005\u3002\u201d\u8f89\u745e\u751f\u7269\u5236\u836f\u96c6\u56e2\u4e2d\u56fd\u533a\u9996\u5e2d\u8fd0\u8425\u5b98\u5434\u7428\u8bf4\u5230\uff0c\u201c\u6b64\u6b21\u542f\u52a8\u4f1a\u6807\u5fd7\u7740\u8f89\u745e\u4e0e\u57fa\u77f3\u6218\u7565\u5408\u4f5c\u7684\u771f\u6b63\u843d\u5730\uff0c\u53cc\u65b9\u5c06\u5728\u5408\u4f5c\u4e2d\u4e92\u76f8\u52a9\u529b\uff0c\u52a0\u901f\u4f18\u79c0\u80bf\u7624\u514d\u75ab\u836f\u7269\u7684\u4e0a\u5e02\u548c\u5546\u4e1a\u5316\uff0c\u8ba9\u60a3\u8005\u66f4\u5feb\u83b7\u5f97\u521b\u65b0\u6cbb\u7597\u836f\u7269\uff0c\u63a8\u52a8\u2018\u5065\u5eb7\u4e2d\u56fd2030\u2019\u76ee\u6807\u7684\u8fbe\u6210\u3002\u201d \u57fa\u77f3\u836f\u4e1a\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u6c5f\u5b81\u519b\u535a\u58eb\u8868\u793a\uff1a\u201c\u8f89\u745e\u548c\u57fa\u77f3\u836f\u4e1a\u6210\u4e3a\u6218\u7565\u5408\u4f5c\u4f19\u4f34\uff0c\u4f53\u73b0\u4e86\u53cc\u65b9\u7684\u76f8\u4e92\u4fe1\u4efb\u4e0e\u8ba4\u53ef\u3002\u764c\u75c7\u5728\u4e2d\u56fd\u5b58\u5728\u5de8\u5927\u7684\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u9700\u8981\u591a\u65b9\u643a\u624b\u5171\u8fdb\uff0c\u6b64\u6b21\u57fa\u77f3\u836f\u4e1a\u548c\u8f89\u745e\u7684\u6218\u7565\u5408\u4f5c\u5c06\u8fdb\u4e00\u6b65\u52a9\u529b\u53cc\u65b9\u7684\u5546\u4e1a\u5316\u5e03\u5c40\u548c\u4ea7\u54c1\u7ba1\u7ebf\u5e03\u5c40\uff0c\u529b\u4e89\u5c06\u66f4\u591a\u7684\u521b\u65b0\u80bf\u7624\u6cbb\u7597\u4ea7\u54c1\u5e26\u7ed9\u5e7f\u5927\u4e2d\u56fd\u60a3\u8005\u3002\u201d \u5173\u4e8e\u8212\u683c\u5229\u5355\u6297 \u8212\u683c\u5229\u5355\u6297\u662f\u7531\u57fa\u77f3\u836f\u4e1a\u5f00\u53d1\u7684\u5728\u7814\u6297PD-L1\u5355\u514b\u9686\u6297\u4f53\u3002\u8212\u683c\u5229\u5355\u6297\u7684\u5f00\u53d1\u57fa\u4e8e\u7531\u7f8e\u56fdLigand\u516c\u53f8\u6388\u6743\u5f15\u8fdb\u7684OmniRat&reg;\u8f6c\u57fa\u56e0\u52a8\u7269\u5e73\u53f0\u3002\u8be5\u5e73\u53f0\u53ef\u4e00\u7ad9\u5f0f\u4ea7\u751f\u5168\u4eba\u6e90\u6297\u4f53\u3002\u4f5c\u4e3a\u4e00\u79cd\u5168\u4eba\u6e90\u5168\u957f\u6297PD-L1\u5355\u514b\u9686\u6297\u4f53\uff0c\u8212\u683c\u5229\u5355\u6297\u662f\u4e00\u79cd\u6700\u63a5\u8fd1\u4eba\u4f53\u7684\u5929\u7136G\u578b\u514d\u75ab\u7403\u86cb\u767d4\uff08IgG4\uff09\u5355\u6297\u836f\u7269\u3002\u8212\u683c\u5229\u5355\u6297\u5728\u60a3\u8005\u4f53\u5185\u4ea7\u751f\u514d\u75ab\u539f\u6027\u53ca\u76f8\u5173\u6bd2\u6027\u7684\u98ce\u9669\u66f4\u4f4e\uff0c\u8fd9\u4f7f\u5f97\u8212\u683c\u5229\u5355\u6297\u4e0e\u540c\u7c7b\u836f\u7269\u76f8\u6bd4\u4f53\u73b0\u51fa\u6f5c\u5728\u7684\u72ec\u7279\u4f18\u52bf\u3002 \u8212\u683c\u5229\u5355\u6297\u5df2\u5728\u4e2d\u56fd\u5b8c\u6210I\u671f\u4e34\u5e8a\u7814\u7a76\u5242\u91cf\u722c\u5761\u3002\u5728Ia\u671f\u548cIb\u671f\u7814\u7a76\u4e2d\uff0c\u8212\u683c\u5229\u5355\u6297\u5728\u591a\u4e2a\u9002\u5e94\u8bc1\u4e2d\u5747\u8868\u73b0\u51fa\u826f\u597d\u7684\u6297\u80bf\u7624\u6d3b\u6027\u548c\u8010\u53d7\u6027\u3002 \u76ee\u524d\uff0c\u8212\u683c\u5229\u5355\u6297\u6b63\u5728\u8fdb\u884c\u591a\u9879\u4e34\u5e8a\u7814\u7a76\uff0c\u9664\u4e86\u4e00\u9879\u7f8e\u56fd\u6865\u63a5\u6027I\u671f\u7814\u7a76\u5916\uff0c\u5728\u4e2d\u56fd\uff0c\u8212\u683c\u5229\u5355\u6297\u6b63\u9488\u5bf9\u591a\u4e2a\u764c\u79cd\u5f00\u5c55\u4e00\u9879\u591a\u81c2Ib\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u4e00\u9879\u9488\u5bf9\u6dcb\u5df4\u7624\u7684II\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76\uff0c\u4ee5\u53ca\u56db\u9879\u5206\u522b\u5728III\u3001IV\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u80c3\u764c\u548c\u98df\u7ba1\u764c\u7684III\u671f\u6ce8\u518c\u4e34\u5e8a\u7814\u7a76\u3002\u5176\u4e2d\u8212\u683c\u5229\u5355\u6297\u6cbb\u7597IV\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u7684III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u8fbe\u5230\u4e3b\u8981\u7ec8\u70b9\uff0cNDA\u5df2\u7ecf\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u53d7\u7406\u3002 \u5173\u4e8e\u8f89\u745e \u5728\u8f89\u745e\uff0c\u6211\u4eec\u81f4\u529b\u4e8e\u8fd0\u7528\u79d1\u5b66\u4ee5\u53ca\u6211\u4eec\u7684\u5168\u7403\u8d44\u6e90\u6765\u63d0\u4f9b\u80fd\u5ef6\u957f\u5e76\u660e\u663e\u6539\u5584\u4eba\u7c7b\u5bff\u547d\u7684\u6cbb\u7597\u3002\u5728\u533b\u7597\u536b\u751f\u4ea7\u54c1\uff08\u5305\u62ec\u521b\u65b0\u836f\u548c\u75ab\u82d7\uff09\u7684\u63a2\u7d22\u3001\u7814\u53d1\u548c\u751f\u4ea7\u8fc7\u7a0b\u4e2d\uff0c\u6211\u4eec\u5747\u5efa\u7acb\u4e86\u8d28\u91cf\u3001\u5b89\u5168\u548c\u4ef7\u503c\u6807\u51c6\u3002\u6bcf\u5929\uff0c\u53d1\u8fbe\u548c\u65b0\u5174\u5e02\u573a\u7684\u8f89\u745e\u5458\u5de5\u90fd\u81f4\u529b\u4e8e\u63a8\u8fdb\u5065\u5eb7\uff0c\u4ee5\u53ca\u80fd\u591f\u5e94\u5bf9\u6211\u4eec\u8fd9\u4e2a\u65f6\u4ee3\u6700\u4e3a\u68d8\u624b\u7684\u75be\u75c5\u7684\u9884\u9632\u548c\u6cbb\u7597\u65b9\u6848\u3002\u8f89\u745e\u8fd8\u4e0e\u4e16\u754c\u5404\u5730\u7684\u533b\u7597\u536b\u751f\u4e13\u4e1a\u4eba\u58eb\u3001\u653f\u5e9c\u548c\u793e\u533a\u5408\u4f5c\uff0c\u652f\u6301\u4e16\u754c\u5404\u5730\u7684\u4eba\u4eec\u80fd\u591f\u83b7\u5f97\u66f4\u4e3a\u53ef\u9760\u548c\u53ef\u627f\u4ed8\u7684\u533b\u7597\u536b\u751f\u670d\u52a1\u3002\u8fd9\u4e0e\u8f89\u745e\u4f5c\u4e3a\u4e00\u5bb6\u5353\u8d8a\u7684\u521b\u65b0\u751f\u7269\u5236\u836f\u516c\u53f8\u7684\u8d23\u4efb\u662f\u4e00\u81f4\u7684\u3002170\u591a\u5e74\u6765\uff0c\u8f89\u745e\u4e00\u76f4\u52aa\u529b\u4e3a\u4eba\u4eec\u63d0\u4f9b\u66f4\u597d\u3001\u66f4\u4f18\u8d28\u7684\u670d\u52a1\u3002\u5982\u9700\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u767b\u5f55 www.pfizer.com.cn\u3002 \u5173\u4e8e\u57fa\u77f3\u836f\u4e1a \u57fa\u77f3\u836f\u4e1a\u662f\u4e00\u5bb6\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u521b\u65b0\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u53ca\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\uff0c\u4ee5\u6ee1\u8db3\u4e2d\u56fd\u548c\u5168\u7403\u764c\u75c7\u60a3\u8005\u7684\u6bb7\u5207\u533b\u7597\u9700\u6c42\u3002\u6210\u7acb\u4e8e2015\u5e74\u5e95\uff0c\u57fa\u77f3\u836f\u4e1a\u5df2\u96c6\u7ed3\u4e86\u4e00\u652f\u5728\u65b0\u836f\u7814\u53d1\u3001\u4e34\u5e8a\u7814\u7a76\u4ee5\u53ca\u5546\u4e1a\u5316\u65b9\u9762\u62e5\u6709\u4e30\u5bcc\u7ecf\u9a8c\u7684\u4e16\u754c\u7ea7\u7ba1\u7406\u56e2\u961f\u3002\u516c\u53f8\u4ee5\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u8054\u5408\u7597\u6cd5\u4e3a\u6838\u5fc3\uff0c\u5efa\u7acb\u4e86\u4e00\u676116\u79cd\u80bf\u7624\u5019\u9009\u836f\u7269\u7ec4\u6210\u7684\u4e30\u5bcc\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u5176\u4e2d5\u6b3e\u540e\u671f\u5019\u9009\u836f\u7269\u6b63\u5904\u4e8e\u5173\u952e\u6027\u4e34\u5e8a\u8bd5\u9a8c\u6216\u6ce8\u518c\u9636\u6bb5\u3002\u51ed\u501f\u7ecf\u9a8c\u4e30\u5bcc\u7684\u7ba1\u7406\u56e2\u961f\u3001\u4e30\u5bcc\u7684\u7ba1\u7ebf\u3001\u4e13\u6ce8\u4e8e\u4e34\u5e8a\u5f00\u53d1\u7684\u4e1a\u52a1\u6a21\u5f0f\u548c\u5145\u88d5\u8d44\u91d1\uff0c\u57fa\u77f3\u836f\u4e1a\u7684\u613f\u666f\u662f\u6210\u4e3a\u4eab\u8a89\u5168\u7403\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u5f15\u9886\u653b\u514b\u764c\u75c7\u4e4b\u8def\u3002\u5982\u9700\u4e86\u89e3\u6709\u5173\u57fa\u77f3\u836f\u4e1a\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1awww.cstonepharma.com\u3002 [1] 2019\u5e74\u5168\u56fd\u764c\u75c7\u62a5\u544a\uff0c\u4e2d\u534e\u4eba\u6c11\u5171\u548c\u56fd\u56fd\u5bb6\u536b\u751f\u5065\u5eb7\u59d4\u5458\u4f1a\u56fd\u5bb6\u80bf\u7624\u8d28\u63a7\u4e2d\u5fc3http:\/\/www.china-rt.cn\/special\/846.html &nbsp; \u76f8\u5173\u94fe\u63a5 : http:\/\/www.pfizer.com.cn&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/2020121617560014578\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":14582,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-14578","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/14578","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=14578"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/14578\/revisions"}],"predecessor-version":[{"id":14581,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/14578\/revisions\/14581"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/14582"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=14578"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=14578"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=14578"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}