{"id":115562,"date":"2025-03-21T18:10:00","date_gmt":"2025-03-21T11:10:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/20250321181000115562"},"modified":"2025-03-23T00:36:19","modified_gmt":"2025-03-22T16:36:19","slug":"%e8%85%be%e7%9b%9b%e5%8d%9a%e8%8d%af%e5%8f%91%e5%b8%832024%e5%b9%b4%e5%ba%a6%e5%85%a8%e5%b9%b4%e8%b4%a2%e5%8a%a1%e4%b8%9a%e7%bb%a9%e5%8f%8a%e5%85%ac%e5%8f%b8%e6%9c%80%e6%96%b0%e8%bf%9b%e5%b1%95","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/20250321181000115562","title":{"rendered":"\u817e\u76db\u535a\u836f\u53d1\u5e032024\u5e74\u5ea6\u5168\u5e74\u8d22\u52a1\u4e1a\u7ee9\u53ca\u516c\u53f8\u6700\u65b0\u8fdb\u5c55"},"content":{"rendered":"<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/www.xinwengao.com\/cn\/wp-content\/uploads\/Logo-680.jpg\" border=\"0\" alt=\"\" title=\"logo\" hspace=\"0\" vspace=\"0\" width=\"118\" 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rel=\"nofollow\">\u817e\u76db\u535a\u836f\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8<\/a>\uff08&quot;\u817e\u76db\u535a\u836f&quot;\u6216&quot;\u516c\u53f8&quot;\uff0c\u80a1\u7968\u4ee3\u7801\uff1a2137.HK\uff09\uff0c\u4e00\u5bb6\u81f4\u529b\u4e8e\u9488\u5bf9\u60a3\u8005\u533b\u7597\u9700\u6c42\u672a\u88ab\u6ee1\u8db3\u7684\u75be\u75c5\u5f00\u53d1\u6cbb\u7597\u65b9\u6848\uff0c\u4ee5\u6539\u5584\u60a3\u8005\u5065\u5eb7\u72b6\u51b5\u548c\u6cbb\u7597\u9009\u62e9\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u4eca\u65e5\u53d1\u5e03\u6700\u65b0\u516c\u53f8\u8fdb\u5c55\u5e76\u62a5\u544a\u622a\u81f32024\u5e7412\u670831\u65e5\u7684\u5e74\u5ea6\u8d22\u52a1\u4e1a\u7ee9\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">\n<\/p><\/div>\n<p>2024\u5e74\uff0c\u817e\u76db\u535a\u836f\u6301\u7eed\u63a8\u8fdb\u5176\u6838\u5fc3\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u529f\u80fd\u6027\u6cbb\u6108\u9879\u76ee\uff0c\u5e76\u4ece\u6b63\u5728\u8fdb\u884c\u76842\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u83b7\u5f97\u4e86\u5173\u952e\u6570\u636e\uff0c\u652f\u6301\u5176\u901a\u8fc7\u514d\u75ab\u8c03\u8282\u4e0e\u964d\u4f4e\u8868\u9762\u6297\u539f\u53cc\u7ba1\u9f50\u4e0b\u7684\u65b9\u5f0f\u63d0\u9ad8\u60a3\u8005\u529f\u80fd\u6027\u6cbb\u6108\u7387\u7684\u76ee\u6807\u3002\u8fd9\u4e9b\u6570\u636e\u8868\u660e\uff0cBRII-179\uff08\u4e00\u79cd\u57fa\u4e8e\u91cd\u7ec4<span id=\"spanHghlt3aaa\">\u86cb\u767d<\/span>\u7684HBV\u514d\u75ab\u7597\u6cd5\uff09\u6709\u671b\u8bc6\u522b\u53ef\u80fd\u5bf9\u6cbb\u6108\u6027\u7597\u6cd5\u4ea7\u751f\u5e94\u7b54\u7684\u60a3\u8005\uff0c\u4ece\u800c\u4e3a\u63a8\u8fdb\u6cbb\u6108\u6027\u7597\u6cd5\u8d77\u5230\u5173\u952e\u6027\u4f5c\u7528\u3002\u4e24\u98792b\u671f\u7814\u7a76ENRICH\u548cENHANCE\u5df2\u5b8c\u6210\u5168\u90e8\u5165\u7ec4\uff0c\u5c06\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u8fd9\u4e9b\u91cd\u8981\u53d1\u73b0\u3002\u5176\u4e2dENSURE\u7814\u7a76\u6cbb\u7597\u7ed3\u675f\u65f6\uff08EOT\uff09\u6570\u636e\u663e\u793a\uff0c\u9776\u5411HBV\u7684\u5c0f\u5e72\u6270\u6838\u7cd6\u6838\u9178\uff08siRNA\uff09\u836f\u7269elebsiran\u5bf9\u53d6\u5f97\u66f4\u9ad8HBV\u529f\u80fd\u6027\u6cbb\u6108\u7387\u8d77\u5230\u76f4\u63a5\u4f5c\u7528\u3002\u76ee\u524delebsiran\u6b63\u5728\u8fdb\u884c\u591a\u9879\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8bc4\u4f30\u5176\u4e0e\u817e\u76db\u535a\u836f\u7684\u5176\u4ed6\u8d44\u4ea7\u7684\u8054\u7528\uff0c\u5305\u62ecVir 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id=\"spanHghlt7085\">\u6297\u4f53\uff09<\/span>\u5f00\u5c55\u7684\u8bd5\u9a8c\u3002\u8fd9\u4e9b\u7814\u7a76\u5373\u5c06\u57282025\u5e74\u516c\u5e03\u7684\u6570\u636e\uff0c\u5c06\u4e3a\u516c\u53f8\u7684\u540e\u671f\u5f00\u53d1\u53ca\u6ce8\u518c\u7b56\u7565\u5e26\u6765\u6307\u5f15\u3002\u817e\u76db\u535a\u836f\u4ecd\u67093.357\u4ebf\u7f8e\u5143\u7684\u5145\u8db3\u73b0\u91d1\u50a8\u5907\uff0c\u8db3\u4ee5\u652f\u6301\u516c\u53f8\u5b8c\u6210\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u6108\u540e\u671f\u5f00\u53d1\u8ba1\u5212\u3002&nbsp;<\/p>\n<p>\u817e\u76db\u535a\u836f\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u6d2a\u5fd7\u535a\u58eb\u8868\u793a\uff1a&quot;\u6211\u4eec2024\u5e74\u53d6\u5f97\u7684\u591a\u9879\u91cd\u8981\u91cc\u7a0b\u7891\u4ece\u4e34\u5e8a\u548c\u6218\u7565\u5c42\u9762\u5f3a\u5316\u4e86\u817e\u76db\u535a\u836f\u8986\u76d6\u591a\u79cd\u4f5c\u7528\u673a\u5236\u7684HBV\u4ea7\u54c1\u7ec4\u5408\u3002\u591a\u9879\u8054\u5408\u7597\u6cd5\u7814\u7a76\u6570\u636e\u663e\u793a\uff0c\u6211\u4eec\u5dee\u5f02\u5316\u7684HBV\u8d44\u4ea7\u6709\u671b\u901a\u8fc7\u591a\u91cd\u673a\u5236\u7684\u7597\u6cd5\u4e3a\u66f4\u5e7f\u6cdb\u7684\u4e59\u809d\u60a3\u8005\u7fa4\u4f53\u5e26\u6765\u66f4\u9ad8\u7684\u529f\u80fd\u6027\u6cbb\u6108\u7387\u3002\u901a\u8fc7\u5bf9BRII-179\u7684\u6218\u7565\u6027\u6536\u8d2d\uff0c\u548c\u5c06\u5728\u4eca\u660e\u4e24\u5e74\u9646\u7eed\u516c\u5e03\u6570\u636e\u7684\u4e09\u9879\u5728\u78142b\u671f\u7814\u7a76\uff0c\u6211\u4eec\u6b63\u5728\u4e3a\u6162\u6027\u4e59\u809d\u60a3\u8005\u5f00\u53d1\u591a\u5143\u7684\u6cbb\u6108\u6027\u6cbb\u7597\u65b9\u6848\u3002&quot;&nbsp;<\/p>\n<p><b><u>\u4e34\u5e8a\u5f00\u53d1\u8fdb\u5c55<\/u><\/b><\/p>\n<p>\u817e\u76db\u535a\u836f\u6b63\u79ef\u6781\u63a8\u52a8\u5176\u521b\u65b0\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u91cd\u70b9\u805a\u7126\u6838\u5fc3HBV\u9879\u76ee\u7684\u540e\u671f\u4e34\u5e8a\u5f00\u53d1\u3002&nbsp;<\/p>\n<p><b><i>HBV\u9879\u76ee&nbsp; 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type=\"disc\">\n<li>ENHANCE\u7814\u7a76\uff1a2025\u5e741\u6708\u5b8c\u6210\u5165\u7ec4\u3002\u8be52b\u671f\u968f\u673a\u53cc\u76f2\u7814\u7a76\u8bc4\u4f30BRII-179\u3001elebsiran\u8054\u5408PEG-IFN\u03b1\u5bf9\u6bd4PEG-IFN\u03b1\u5355\u836f\u5728\u975e\u809d\u786c\u5316\u6162\u6027HBV\u611f\u67d3\u60a3\u8005\uff08\u63a5\u53d7\u6838\u82f7\u9178\u9006\u8f6c\u5f55\u9176\u6291\u5236\u5242\uff08NRTI\uff09\u80cc\u666f\u6cbb\u7597\uff09\u4e2d\u7684\u7597\u6548\u4e0e\u5b89\u5168\u6027\u3002<\/li>\n<li>ENSURE\u7814\u7a76\uff1a\u57282024\u5e7411\u6708\u4e3e\u884c\u7684\u7f8e\u56fd\u809d\u75c5\u7814\u7a76\u5b66\u4f1a\uff08AASLD\uff09\u5e74\u4f1a\u4e0a\uff0c\u817e\u76db\u535a\u836f\u4ee5\u6700\u65b0\u7a81\u7834\u6027\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\u4e86ENSURE\u7814\u7a7648\u5468\u6cbb\u7597\u7ed3\u675f\u65f6\u6570\u636e\u3002\u6570\u636e\u663e\u793a\uff0celebsiran\u8054\u5408PEG-IFN\u03b1\u6cbb\u7597\u7ec4\u60a3\u8005\u7684\u4e59\u809d\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u6e05\u9664\u7387\u663e\u8457\u9ad8\u4e8e\u5e72\u6270\u7d20\u5355\u836f\u7ec4\u3002ENSURE\u7814\u7a76\u6807\u5fd7\u7740\u4e1a\u5185\u9996\u6b21\u901a\u8fc7\u4e0e\u5e72\u6270\u7d20\u5355\u836f\u5934\u5bf9\u5934\u7684\u6bd4\u8f83\uff0c\u660e\u786e\u4e86siRNA\uff08elebsiran\uff09\u5728\u4e0e\u5e72\u6270\u7d20\u8054\u7528\u65f6\u5bf9\u529f\u80fd\u6027\u6cbb\u6108\u7684\u8d21\u732e\uff0c\u51f8\u663e\u5176\u63d0\u5347HBV\u529f\u80fd\u6027\u6cbb\u6108\u7387\u7684\u6f5c\u529b\u3002\u817e\u76db\u535a\u836f\u5c06\u4e8e2025\u5e74\u4e0a\u534a\u5e74\u516c\u5e03\u66f4\u591a\u5173\u952e\u6570\u636e\u3002<\/li>\n<li>ENRICH\u7814\u7a76\uff1aENSURE \u7814\u7a76\u8fd8\u5bf9\u66fe\u63a5\u53d7\u8fc7 BRII-179 \u6cbb\u7597\u7684\u60a3\u8005\u8fdb\u884c\u4e86\u7814\u7a76\u3002\u57fa\u4e8eENSURE\u7814\u7a76\u961f\u52174\u7684\u65e9\u671f\u6570\u636e\uff08\u5c06\u4e8e2025\u5e74APASL\u516c\u5e03\uff09\uff0cENRICH\u7814\u7a76\u4e8e2024\u5e7411\u6708\u5b8c\u6210\u5165\u7ec4\uff0c\u65e8\u5728\u8bc4\u4f30BRII-179\u4f5c\u4e3a\u6cbb\u6108\u65b9\u6848\u4e2d\u6fc0\u6d3bHBV\u7279\u5e94\u6027\u514d\u75ab\u7684\u4e00\u90e8\u5206\uff0c\u5e76\u5c06\u5176\u4f5c\u4e3a\u4e00\u79cd\u5de5\u5177\uff0c\u7528\u4e8e\u8bc6\u522b\u514d\u75ab\u5e94\u7b54\u60a3\u8005\uff0c\u4ee5\u63d0\u9ad8\u529f\u80fd\u6027\u6cbb\u6108\u7684\u53ef\u80fd\u6027\u3002<\/li>\n<li>\u817e\u76db\u535a\u836f\u7684\u5f00\u53d1\u5408\u4f5c\u4f19\u4f34Vir Biotechnology\u57282024\u5e7411\u6708AASLD\u5e74\u4f1a\u4e0a\u516c\u5e03\u4e86\u51762\u671f<a href=\"https:\/\/investors.vir.bio\/news\/news-details\/2024\/Vir-Biotechnology-Announces-Positive-End-of-Treatment-Results-for-Tobevibart-and-Elebsiran-Combinations-in-Chronic-Hepatitis-B-from-the-MARCH-Study-at-AASLD-The-Liver-Meeting\/default.aspx\" target=\"_blank\" rel=\"nofollow\">MARCH<\/a>\u7814\u7a76\u548c<a href=\"https:\/\/investors.vir.bio\/news\/news-details\/2024\/Vir-Biotechnology-Presents-Positive-Chronic-Hepatitis-Delta-Clinical-Trial-Data-and-Announces-Initiation-of-Phase-3-Registrational-Program\/default.aspx\" target=\"_blank\" rel=\"nofollow\">SOLSTICE<\/a>\u7814\u7a76\u6570\u636e.\n<ul type=\"disc\">\n<li>Vir Biotechnology\u8fd1\u671f\u542f\u52a8\u4e863\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8cECLIPSE\u9879\u76ee\u4ee5\u5728\u8bc4\u4f30tobevibart\u4e0eelebsiran\u8054\u5408\u7597\u6cd5\u6cbb\u7597\u6162\u6027\u4e01\u578b\u809d\u708e\uff08CHD\uff09\u3002<\/li>\n<li>2024\u5e746\u6708\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6388\u4e88Vir Biotechnology\u7528\u4e8e\u6cbb\u7597CHD\u7684tobevibart\u548celebsiran \u5feb\u901f\u901a\u9053\u8ba4\u8bc1\uff1b2024\u5e7411\u6708\u83b7\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u5b64\u513f\u836f\u8ba4\u8bc1\uff1b12\u6708\u83b7FDA\u7a81\u7834\u6027\u6cbb\u7597\u54c1\u79cd\u8ba4\u5b9a\u53caEMA\u7684PRIME\u8ba4\u8bc1\uff08PRIME Designation\uff09\u3002<\/li>\n<\/ul>\n<\/li>\n<li>2024\u5e745\u6708\uff0ctobevibart\u4e0eelebsiran\u83b7\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u7a81\u7834\u6027\u6cbb\u7597\u54c1\u79cd\u8ba4\u5b9a\u3002<\/li>\n<\/ul>\n<p><b><i>\u5176\u4ed6\u4e34\u5e8a\u9879\u76ee&nbsp; <\/i><\/b><\/p>\n<p>\u817e\u76db\u535a\u836f\u6b63\u79ef\u6781\u4e3aHIV\u3001\u591a\u91cd\u8010\u836f\/\u5e7f\u6cdb\u8010\u836f\u611f\u67d3\u53ca\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u9886\u57df\u7684\u5019\u9009\u836f\u7269\u5bfb\u6c42\u5916\u90e8\u5408\u4f5c\u3002&nbsp;<\/p>\n<ul type=\"disc\">\n<li>2024\u5e7410\u6708\uff0c\u817e\u76db\u535a\u836f\u83b7\u5f97\u4e86 NMPA CDE \u7684 IND \u6279\u51c6\uff0c\u5728\u4e2d\u56fd\u5f00\u5c55BRII-693\uff08\u65b0\u578b\u591a\u9ecf\u83cc\u7d20\uff0c\u7528\u4e8e\u6cbb\u7597\u4e25\u91cd\u9769\u5170\u6c0f\u9634\u6027\u83cc\u611f\u67d3\uff09\u76841\u671f\u836f\u4ee3\u52a8\u529b\u5b66\u6865\u63a5\u8bd5\u9a8c\u3002\u6b64\u524d1\u671f\u6570\u636e\u5df2\u4e8e2024\u5e7412\u6708\u53d1\u8868\u4e8e\u300a<i>Antimicrobial Agents and Chemotherapy<\/i>\u300b\u671f\u520a\uff0c\u652f\u6301\u672a\u6765\u9488\u5bf9\u533b\u9662\u83b7\u5f97\u6027\u7ec6\u83cc\u6027\u80ba\u708e\/\u547c\u5438\u673a\u76f8\u5173\u7ec6\u83cc\u6027\u80ba\u708e\u7684\u5168\u74033\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\u3002\u817e\u76db\u535a\u836f\u62e5\u6709BRII-693\u7684\u5168\u7403\u72ec\u5bb6\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u6743\u76ca\u3002&nbsp;<\/li>\n<\/ul>\n<p><b><u>2024\u5e74\u5ea6\u4f01\u4e1a\u4eae\u70b9\u53ca\u8fd1\u671f\u52a8\u6001&nbsp;<\/u><\/b><\/p>\n<ul type=\"disc\">\n<li>\u80a1\u4efd\u56de\u8d2d\uff1a2024\u5e7412\u6708\uff0c\u516c\u53f8\u5ba3\u5e03\u6279\u51c66,000\u4e07\u6e2f\u5143\u80a1\u7968\u56de\u8d2d\u8ba1\u5212\uff08\u5360\u5df2\u53d1\u884c\u80a1\u4efd10%\uff09\uff0c\u5f70\u663e\u4e86\u516c\u53f8\u5bf9\u5176\u524d\u666f\u7684\u4fe1\u5fc3\u3002\u622a\u81f32025\u5e743\u670821\u65e5\uff0c\u516c\u53f8\u5df2\u5728\u9999\u6e2f\u8054\u4ea4\u6240\u56de\u8d2d\u7ea6443.3\u4e07\u80a1\uff0c\u8017\u8d44\u7ea6530\u4e07\u6e2f\u5143\u3002<\/li>\n<li>\u8d44\u4ea7\u6536\u8d2d\uff1a2024\u5e7412\u6708\uff0c\u516c\u53f8\u4e0eVBI Vaccines, Inc. \u53ca\u5176\u5173\u8054\u5b50\u516c\u53f8\u7b7e\u7f72\u4e86\u4e00\u9879\u8d44\u4ea7\u8d2d\u4e70\u534f\u8bae\uff0c\u4ee5<span id=\"spanHghlt396b\">1,800<\/span>\u4e07\u7f8e\u5143\u603b\u4ef7\u6536\u8d2dBRII-179\u5b8c\u6574\u77e5\u8bc6\u4ea7\u6743\u53ca\u76f8\u5173\u8d44\u4ea7\u3002\u8be5\u534f\u8bae\u53d6\u6d88\u4e86\u672a\u6765\u5411VBI\u652f\u4ed8\u7684\u4e0eBRII-179\u548cPreHevbri<sup> TM<\/sup>\u76f8\u5173\u7684\u8d39\u7528\uff0c\u5e76\u89e3\u9664\u4e86\u4e4b\u524d\u4e8e2024\u5e742\u670814\u65e5\u5ba3\u5e03\u7684\u534f\u8bae\u3002\u6b64\u6b21\u6536\u8d2d\u4e3a\u817e\u76db\u535a\u836f\u5e26\u6765\u4e86\u66f4\u591a\u7684\u5546\u4e1a\u83b7\u76ca\uff0c\u540c\u65f6\u786e\u4fdd\u4e86 BRII-179 \u7684\u4e0d\u95f4\u65ad\u4e34\u5e8a\u4f9b\u5e94\u3002\u516c\u53f8\u5c06\u7ee7\u7eed\u5f00\u53d1\u8fd9\u4e00\u8d44\u4ea7\uff0c\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u7684\u7814\u7a76\u652f\u6301 BRII-179 \u5177\u6709\u63d0\u9ad8 HBV \u60a3\u8005\u5bf9\u6cbb\u7597\u53cd\u5e94\u7684\u6f5c\u529b\u3002<\/li>\n<\/ul>\n<p><b><u>2024\u5e74\u5ea6\u8d22\u52a1\u4e1a\u7ee9<\/u><\/b><\/p>\n<ul type=\"disc\">\n<li>\u622a\u81f32024\u5e7412\u670831\u65e5\uff0c\u6211\u4eec\u7684\u94f6\u884c\u5b58\u6b3e\u3001\u73b0\u91d1\u53ca\u73b0\u91d1\u7b49\u4ef7\u7269\u4e3a\u4eba\u6c11\u5e0124.134\u4ebf\u5143\uff0c\u4e0e\u622a\u81f32023\u5e7412\u670831\u65e5\u7684\u4eba\u6c11\u5e0126.614\u4ebf\u5143\u76f8\u6bd4\uff0c\u51cf\u5c11\u4e86\u4eba\u6c11\u5e012.48\u4ebf\u5143\u62169.3%\u3002\u8be5\u51cf\u5c11\u4e3b\u8981\u662f\u7531\u4e8e\u65e5\u5e38\u8425\u8fd0\u53ca\u7814\u53d1\u6d3b\u52a8\u652f\u51fa\u3002<\/li>\n<li>\u622a\u81f32024\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\uff0c\u5176\u4ed6\u6536\u5165\u4e3a\u4eba\u6c11\u5e011.414\u4ebf\u5143\uff0c\u4e0e\u622a\u81f32023\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e011.637\u4ebf\u5143\u76f8\u6bd4\uff0c\u51cf\u5c11\u4eba\u6c11\u5e012,230\u4e07\u5143\u621613.6%\u3002\u8fd9\u4e3b\u8981\u662f\u7531\u4e8e\u7f8e\u5143\u53ca\u6e2f\u5143\u5b9a\u671f\u5b58\u6b3e\u5229\u7387\u4e0b\u964d\u5bfc\u81f4\u94f6\u884c\u5229\u606f\u6536\u5165\u51cf\u5c11\u4eba\u6c11\u5e012,080\u4e07\u5143\u4ee5\u53ca\u5c31\u4e2d\u56fd\u653f\u5e9c\u8865\u52a9\u786e\u8ba4\u7684\u6536\u5165\u51cf\u5c11\u3002<\/li>\n<li>\u622a\u81f32024\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\uff0c\u7814\u53d1\u5f00\u652f\u4e3a\u4eba\u6c11\u5e012.498\u4ebf\u5143\uff0c\u4e0e\u622a\u81f32023\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e014.027\u4ebf\u5143\u76f8\u6bd4\uff0c\u51cf\u5c11\u4e86\u4eba\u6c11\u5e011.529\u4ebf\u5143\u621638.0%\u3002\u8be5\u51cf\u5c11\u4e3b\u8981\u5f52\u56e0\u4e8e\u62a5\u544a\u671f\u95f4\u7ba1\u7ebf\u6392\u5e8f\u53ca\u7ec4\u7ec7\u4f18\u5316\uff0c\u5bfc\u81f4\u7b2c\u4e09\u65b9\u627f\u5305\u6210\u672c\u51cf\u5c11\u4e86\u4eba\u6c11\u5e017,930\u4e07\u5143\u53ca\u96c7\u5458\u6210\u672c\u51cf\u5c11\u4eba\u6c11\u5e01<span id=\"spanHghltb456\">6,770<\/span>\u4e07\u5143\u3002<\/li>\n<li>\u622a\u81f32024\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\uff0c\u884c\u653f\u5f00\u652f\u4e3a\u4eba\u6c11\u5e011.532\u4ebf\u5143\uff0c\u4e0e\u622a\u81f32023\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e011.965\u4ebf\u5143\u76f8\u6bd4\uff0c\u51cf\u5c11\u4e86\u4eba\u6c11\u5e014,330\u4ebf\u5143\u621622.0%\u3002\u8be5\u51cf\u5c11\u4e3b\u8981\u5f52\u56e0\u4e8e\u62a5\u544a\u671f\u95f4\u7ba1\u7ebf\u6392\u5e8f\u53ca\u7ec4\u7ec7\u4f18\u5316\uff0c\u5bfc\u81f4\u96c7\u5458\u6210\u672c\u51cf\u5c11\u4eba\u6c11\u5e013,970\u4e07\u5143\u3002<\/li>\n<li>\u622a\u81f32024\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\uff0c\u671f\u5185\u4e8f\u635f\u4e3a\u4eba\u6c11\u5e015.124\u4ebf\u5143\uff0c\u4e0e\u622a\u81f32023\u5e7412\u670831\u65e5\u6b62\u5e74\u5ea6\u7684\u4eba\u6c11\u5e011.844\u4ebf\u5143\u76f8\u6bd4\uff0c\u589e\u52a0\u4e86\u4eba\u6c11\u5e013.28\u4ebf\u5143\u6216177.9%\u3002\u4e8f\u635f\u589e\u52a0\u4e3b\u8981\u5f52\u56e0\u4e8e\u6295\u8d44\u76f8\u5173\u4e8f\u635f\u4eba\u6c11\u5e011.261\u4ebf\u5143\u53ca\u51cf\u503c\u8d39\u7528\u4eba\u6c11\u5e019,030\u4e07\u5143\uff0c\u90e8\u5206\u88ab\u7814\u53d1\u5f00\u652f\u53ca\u884c\u653f\u5f00\u652f\u51cf\u5c11\u6240\u62b5\u9500\u3002\u4e0a\u4e00\u5e74\u5ea6\u5f97\u76ca\u4e8e\u4e00\u6b21\u6027\u51fa\u552e\u8d44\u4ea7\u4ea7\u751f\u7684\u91cd\u5927\u6536\u76ca\u4eba\u6c11\u5e011.318\u4ebf\u5143\u53ca\u4e00\u9879\u80a1\u6743\u6295\u8d44\u7684\u80a1\u4ef7\u4e0a\u5347\u4eba\u6c11\u5e011.292\u4ebf\u5143\uff0c\u800c\u672c\u5e74\u5ea6\u5219\u53d7\u540c\u4e00\u9879\u80a1\u6743\u6295\u8d44\u516c\u5141\u4ef7\u503c\u4e0b\u8dcc\u6240\u5f71\u54cd\u3002<\/li>\n<\/ul>\n<p><b><u>\u7535\u8bdd\u4f1a\u8bae\u4fe1\u606f&nbsp; <\/u><\/b><\/p>\n<p>\u516c\u53f8\u5c06\u4e8e\u5c06\u4e8e2025\u5e743\u670831\u65e5\u9999\u6e2f\u65f6\u95f4\u4e0a\u53488:30\uff08\u7f8e\u56fd\u4e1c\u90e8\u65f6\u95f43\u670830\u65e5\u665a\u95f48:30\uff09\u53ec\u5f00\u7535\u8bdd\u4f1a\u8bae\uff08\u4e2d\u6587\u573a\uff09\u3002\u7ba1\u7406\u5c42\u5c06\u5206\u4eab\u5e74\u5ea6\u66f4\u65b0\u53ca\u57283\u670826\u65e5\u81f330\u65e5\u671f\u95f4APASL\u4f1a\u8bae\u4e0a\u5c55\u793a\u7684\u6570\u636e\u3002\u6240\u6709\u53c2\u4f1a\u8005\u987b\u5b8c\u6210\u4f1a\u8bae\u6ce8\u518c\u3002\u6ce8\u518c\u94fe\u63a5\u8bf7\u70b9\u51fb<a href=\"https:\/\/www.comein.cn\/roadshow\/home\/349413\" target=\"_blank\" rel=\"nofollow\"><span id=\"spanHghlt7e9a\">\u8fd9\u91cc<\/span><\/a>\u3002<\/p>\n<p>\u6240\u6709\u53c2\u4f1a\u8005\u987b\u5728\u7535\u8bdd\u4f1a\u8bae\u4e4b\u524d\u901a\u8fc7\u4e0a\u8ff0\u94fe\u63a5\u5b8c\u6210\u5728\u7ebf\u6ce8\u518c\u3002\u6ce8\u518c\u540e\uff0c\u6bcf\u4f4d\u53c2\u4f1a\u8005\u5c06\u6536\u5230\u4e00\u5c01\u7535\u5b50\u90ae\u4ef6\uff0c\u5176\u4e2d\u5305\u542b\u6b64\u6b21\u7535\u8bdd\u4f1a\u8bae\u7684\u91cd\u8981\u4fe1\u606f\uff0c\u5305\u62ec\u7535\u8bdd\u4f1a\u8bae\u65e5\u671f\u3001\u65f6\u95f4\u53ca\u8bbf\u95ee\u94fe\u63a5\u3002\u8be5\u94fe\u63a5\u987b\u4e88\u4ee5\u4fdd\u5bc6\uff0c\u4e0d\u5f97\u4e0e\u5176\u4ed6\u53c2\u4f1a\u8005\u5171\u4eab\u3002\u6b64\u5916\uff0c\u6b64\u7535\u8bdd\u4f1a\u8bae\u7684\u56de\u653e\u5c06\u5728\u4f1a\u8bae\u540e\u63d0\u4f9b\uff0c\u5e76\u53ef\u901a\u8fc7\u8bbf\u95ee\u672c\u516c\u53f8\u7f51\u7ad9<a href=\"https:\/\/www.briibio.com\/cn\/\" target=\"_blank\" rel=\"nofollow\">www.briibio.com<\/a>\u7684\u6295\u8d44\u8005\u5173\u7cfb\u7248\u5757\u83b7\u53d6\u3002<\/p>\n<p>\u672c\u65b0\u95fb\u7a3f\u6d89\u53ca\u7b2c\u4e09\u65b9\u4fe1\u606f\u7684\u5f15\u7528\u3002\u6b64\u7c7b\u4fe1\u606f\u4e0d\u5e94\u88ab\u89c6\u4e3a\u53c2\u8003\u4fe1\u606f\u7eb3\u5165\u672c\u65b0\u95fb\u7a3f\u4e2d\u3002\u817e\u76db\u535a\u836f\u5bf9\u6b64\u7c7b\u7b2c\u4e09\u65b9\u4fe1\u606f\u7684\u4e0d\u8d1f\u4efb\u4f55\u8d23\u4efb\u3002<\/p>\n<p><b>\u5173\u4e8e\u817e\u76db\u535a\u836f&nbsp; 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href=\"https:\/\/www.briibio.com\/cn\/\" target=\"_blank\" rel=\"nofollow\">www.briibio.com<\/a>\u3002<\/p>\n<p><b>\u524d\u77bb\u6027\u58f0\u660e&nbsp; 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Biotechnology, Inc. \uff08&quot;Vir Biotechnology&quot;\uff0c\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aVIR\uff09\u6b63\u5728\u5bf9 tobevibart\uff08\u4e00\u79cd\u9488\u5bf9HBV\u7684\u5e7f\u8c31\u4e2d\u548c\u5355\u514b\u9686\u6297\u4f53\uff09\u5f00\u5c55\u7684\u8bd5\u9a8c\u3002\u8fd9\u4e9b\u7814\u7a76\u5373\u5c06\u57282025\u5e74\u516c\u5e03\u7684\u6570\u636e\uff0c\u5c06\u4e3a\u516c\u53f8\u7684\u540e\u671f\u5f00\u53d1\u53ca\u6ce8\u518c\u7b56\u7565\u5e26\u6765\u6307\u5f15\u3002\u817e\u76db\u535a\u836f\u4ecd\u67093.357\u4ebf\u7f8e\u5143\u7684\u5145\u8db3\u73b0\u91d1\u50a8\u5907\uff0c\u8db3\u4ee5\u652f\u6301\u516c\u53f8\u5b8c\u6210\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u6108\u540e\u671f\u5f00\u53d1\u8ba1\u5212\u3002&nbsp; 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\u4e34\u5e8a\u5f00\u53d1\u8fdb\u5c55 \u817e\u76db\u535a\u836f\u6b63\u79ef\u6781\u63a8\u52a8\u5176\u521b\u65b0\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u91cd\u70b9\u805a\u7126\u6838\u5fc3HBV\u9879\u76ee\u7684\u540e\u671f\u4e34\u5e8a\u5f00\u53d1\u3002&nbsp; HBV\u9879\u76ee&nbsp; \u516c\u53f8\u6b63\u5728\u63a8\u8fdb\u591a\u9879\u5dee\u5f02\u5316HBV\u5019\u9009\u836f\u7269\u7684\u8054\u5408\u7814\u7a76\uff0c\u5305\u62ec\u9776\u5411HBV\u7684siRNA\u836f\u7269elebsiran\u3001\u57fa\u4e8e\u91cd\u7ec4\u86cb\u767d\u7684HBV\u514d\u75ab\u7597\u6cd5BRII-179\u3002\u516c\u53f8\u7684\u5408\u4f5c\u4f19\u4f34 Vir Biotechnology\u516c\u53f8\u4e5f\u6b63\u5728\u63a8\u8fdb elebsiran \u548c tobevibart\uff08\u4e00\u79cd\u9488\u5bf9 HBV \u8868\u9762\u6297\u539f\u7684\u5e7f\u8c31\u4e2d\u548c\u5355\u514b\u9686\u6297\u4f53\uff09\u7684\u591a\u9879\u8054\u5408\u7814\u7a76\u3002 \u901a\u8fc7\u4ee5\u4e0a\u4e09\u79cd\u4e0d\u540c\u6cbb\u7597\u673a\u5236\u7684\u836f\u7269\u7ec4\u5408\u6cbb\u7597HBV\uff0c\u817e\u76db\u535a\u836f\u65e8\u5728\u786e\u5b9a\u9488\u5bf9\u4e0d\u540c\u60a3\u8005\u4e9a\u7fa4\u7684\u6700\u4f73\u6cbb\u6108\u65b9\u6848\uff0c\u53ca\u6700\u9ad8\u6548\u7684\u5ba1\u8bc4\u8def\u5f84\u3002\u968f\u7740\u817e\u76db\u535a\u836f\u5728 HBV \u529f\u80fd\u6027\u6cbb\u6108\u65b9\u9762\u53d6\u5f97\u8fdb\u5c55\uff0c\u516c\u53f8\u6b63\u5728\u8fdb\u884c\u7684ENRICH\uff08\u8bc4\u4f30BRII-179\u5728\u6fc0\u6d3bHBV\u7279\u5f02\u6027\u514d\u75ab\u53ca\u7b5b\u9009\u9ad8\u514d\u75ab\u5e94\u7b54\u60a3\u8005\u4e2d\u7684\u4f5c\u7528\uff09\u548cENSURE\uff08elebsiran\u8054\u5408\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u03b1\uff08PEG-IFN\u03b1\uff09\u5bf9\u7167PEG-IFN\u03b1\u5355\u836f\uff09\u7814\u7a76\u9884\u8ba1\u5c06\u5728 2025-2026 \u5e74\u95f4\u83b7\u5f97\u5173\u952e\u6570\u636e\uff0c\u8fdb\u4e00\u6b65\u4e3a\u540e\u671f\u7814\u7a76\u63d0\u4f9b\u4fe1\u606f\u3002 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ENSURE\u7814\u7a76\uff1a\u57282024\u5e7411\u6708\u4e3e\u884c\u7684\u7f8e\u56fd\u809d\u75c5\u7814\u7a76\u5b66\u4f1a\uff08AASLD\uff09\u5e74\u4f1a\u4e0a\uff0c\u817e\u76db\u535a\u836f\u4ee5\u6700\u65b0\u7a81\u7834\u6027\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\u4e86ENSURE\u7814\u7a7648\u5468\u6cbb\u7597\u7ed3\u675f\u65f6\u6570\u636e\u3002\u6570\u636e\u663e\u793a\uff0celebsiran\u8054\u5408PEG-IFN\u03b1\u6cbb\u7597\u7ec4\u60a3\u8005\u7684\u4e59\u809d\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u6e05\u9664\u7387\u663e\u8457\u9ad8\u4e8e\u5e72\u6270\u7d20\u5355\u836f\u7ec4\u3002ENSURE\u7814\u7a76\u6807\u5fd7\u7740\u4e1a\u5185\u9996\u6b21\u901a\u8fc7\u4e0e\u5e72\u6270\u7d20\u5355\u836f\u5934\u5bf9\u5934\u7684\u6bd4\u8f83\uff0c\u660e\u786e\u4e86siRNA\uff08elebsiran\uff09\u5728\u4e0e\u5e72\u6270\u7d20\u8054\u7528\u65f6\u5bf9\u529f\u80fd\u6027\u6cbb\u6108\u7684\u8d21\u732e\uff0c\u51f8\u663e\u5176\u63d0\u5347HBV\u529f\u80fd\u6027\u6cbb\u6108\u7387\u7684\u6f5c\u529b\u3002\u817e\u76db\u535a\u836f\u5c06\u4e8e2025\u5e74\u4e0a\u534a\u5e74\u516c\u5e03\u66f4\u591a\u5173\u952e\u6570\u636e\u3002 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Vir Biotechnology\u8fd1\u671f\u542f\u52a8\u4e863\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8cECLIPSE\u9879\u76ee\u4ee5\u5728\u8bc4\u4f30tobevibart\u4e0eelebsiran\u8054\u5408\u7597\u6cd5\u6cbb\u7597\u6162\u6027\u4e01\u578b\u809d\u708e\uff08CHD\uff09\u3002 2024\u5e746\u6708\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6388\u4e88Vir Biotechnology\u7528\u4e8e\u6cbb\u7597CHD\u7684tobevibart\u548celebsiran \u5feb\u901f\u901a\u9053\u8ba4\u8bc1\uff1b2024\u5e7411\u6708\u83b7\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u5b64\u513f\u836f\u8ba4\u8bc1\uff1b12\u6708\u83b7FDA\u7a81\u7834\u6027\u6cbb\u7597\u54c1\u79cd\u8ba4\u5b9a\u53caEMA\u7684PRIME\u8ba4\u8bc1\uff08PRIME Designation\uff09\u3002 2024\u5e745\u6708\uff0ctobevibart\u4e0eelebsiran\u83b7\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u7a81\u7834\u6027\u6cbb\u7597\u54c1\u79cd\u8ba4\u5b9a\u3002 \u5176\u4ed6\u4e34\u5e8a\u9879\u76ee&nbsp; \u817e\u76db\u535a\u836f\u6b63\u79ef\u6781\u4e3aHIV\u3001\u591a\u91cd\u8010\u836f\/\u5e7f\u6cdb\u8010\u836f\u611f\u67d3\u53ca\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u9886\u57df\u7684\u5019\u9009\u836f\u7269\u5bfb\u6c42\u5916\u90e8\u5408\u4f5c\u3002&nbsp; 2024\u5e7410\u6708\uff0c\u817e\u76db\u535a\u836f\u83b7\u5f97\u4e86 NMPA CDE \u7684 IND \u6279\u51c6\uff0c\u5728\u4e2d\u56fd\u5f00\u5c55BRII-693\uff08\u65b0\u578b\u591a\u9ecf\u83cc\u7d20\uff0c\u7528\u4e8e\u6cbb\u7597\u4e25\u91cd\u9769\u5170\u6c0f\u9634\u6027\u83cc\u611f\u67d3\uff09\u76841\u671f\u836f\u4ee3\u52a8\u529b\u5b66\u6865\u63a5\u8bd5\u9a8c\u3002\u6b64\u524d1\u671f\u6570\u636e\u5df2\u4e8e2024\u5e7412\u6708\u53d1\u8868\u4e8e\u300aAntimicrobial Agents and Chemotherapy\u300b\u671f\u520a\uff0c\u652f\u6301\u672a\u6765\u9488\u5bf9\u533b\u9662\u83b7\u5f97\u6027\u7ec6\u83cc\u6027\u80ba\u708e\/\u547c\u5438\u673a\u76f8\u5173\u7ec6\u83cc\u6027\u80ba\u708e\u7684\u5168\u74033\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\u3002\u817e\u76db\u535a\u836f\u62e5\u6709BRII-693\u7684\u5168\u7403\u72ec\u5bb6\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u6743\u76ca\u3002&nbsp;&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/20250321181000115562\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":115565,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-115562","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/115562","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=115562"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/115562\/revisions"}],"predecessor-version":[{"id":115564,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/115562\/revisions\/115564"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/115565"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=115562"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=115562"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=115562"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}