{"id":114494,"date":"2024-07-15T16:02:00","date_gmt":"2024-07-15T09:02:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/20240715160200114494"},"modified":"2024-07-16T04:00:18","modified_gmt":"2024-07-15T20:00:18","slug":"%e5%a4%a9%e6%bc%94%e8%8d%af%e4%b8%9a%e5%b0%86%e5%9c%a82024%e5%b9%b4-esmo-%e4%b8%8a%e5%85%ac%e5%b8%83%e5%85%b6%e6%8a%97-ctla-4-safebody-%e5%ae%89%e5%85%a8%e6%8a%97%e4%bd%93-adg126-muzastotug","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/20240715160200114494","title":{"rendered":"\u5929\u6f14\u836f\u4e1a\u5c06\u57282024\u5e74 ESMO \u4e0a\u516c\u5e03\u5176\u6297 CTLA-4 SAFEbody\u00ae \u5b89\u5168\u6297\u4f53 ADG126 (muzastotug) \u8054\u5408\u5e15\u535a\u5229\u73e0\u5355\u6297\u6cbb\u7597MSS CRC\u7684\u6700\u65b0\u6570\u636e"},"content":{"rendered":"

\u4e2d\u56fd\u82cf\u5dde\u548c\u7f8e\u56fd\u5723\u5730\u4e9a\u54e5<\/span>2024\u5e747\u670815\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u5929\u6f14\u836f\u4e1a\uff08\u4ee5\u4e0b\u7b80\u79f0"\u516c\u53f8"\u6216"\u5929\u6f14"\uff09\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aADAG\uff09\u662f\u4e00\u5bb6\u81f4\u529b\u4e8e\u53d1\u73b0\u5e76\u5f00\u53d1\u4ee5\u539f\u521b\u6297\u4f53\u4e3a\u57fa\u77f3\u7684\u65b0\u578b\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u751f\u7269\u5236\u836f\u4f01\u4e1a\uff0c\u516c\u53f8\u4eca\u65e5\u5ba3\u5e03\uff0c\u5c06\u57282024\u5e749\u670813\u65e5\u81f317\u65e5\u4e8e\u897f\u73ed\u7259\u5df4\u585e\u7f57\u90a3\u4e3e\u529e\u7684\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\u5927\u4f1a (ESMO) \u4e0a\u8fdb\u884c\u6d77\u62a5\u5c55\u793a\u3002<\/p>\n

\u6d77\u62a5\u5c06\u516c\u5e03\u6297CTLA-4\u5b89\u5168\u6297\u4f53ADG126\u8054\u5408\u6297PD-1\u836f\u7269\u5e15\u535a\u5229\u73e0\u5355\u6297 (Pembrolizumab) \u7684 1b\/2 \u671f\u7814\u7a76\u7ed3\u679c\u3002\u6d77\u62a5\u6807\u9898\u4e3a\uff1a<\/p>\n

\u6297CTLA-4 SAFEbody®\u5b89\u5168\u6297\u4f53ADG126 (Muzastotug, Muza) \u4e0e \u5e15\u535a\u5229\u73e0\u5355\u6297 (Pembrolizumab) \u8054\u7528\u663e\u8457\u63d0\u9ad8\u4e86\u6cbb\u7597\u6307\u6570\uff0c\u4e8e\u8f6c\u79fb\u6027\u5fae\u536b\u661f\u7a33\u5b9a\u578b\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u4e2d\u89c2\u5bdf\u5230\u7684\u4e34\u5e8a\u83b7\u76ca\u652f\u6301\u8fdb\u4e00\u6b65\u4e34\u5e8a\u5f00\u53d1<\/p>\n

\u66f4\u591a\u8be6\u60c5\uff0c\u53ef\u5728\u53d1\u5e03\u540e\u767b\u9646\u516c\u53f8\u5b98\u65b9\u7f51\u7ad9\u7684\u53d1\u8868\u6587\u732e\u9875\u9762<\/a><\/u>\u67e5\u9605\u76f8\u5173\u6d77\u62a5\u3002<\/p>\n

\u5173\u4e8e\u5929\u6f14\u836f\u4e1a<\/b><\/p>\n

\u5929\u6f14\u836f\u4e1a\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aADAG\uff09\u662f\u5e73\u53f0\u9a71\u52a8\u5e76\u62e5\u6709\u81ea\u4e3b\u5e73\u53f0\u4ea7\u51fa\u7684\u4e34\u5e8a\u4ea7\u54c1\u5f00\u53d1\u9636\u6bb5\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u516c\u53f8\u81f4\u529b\u4e8e\u53d1\u73b0\u5e76\u5f00\u53d1\u4ee5\u539f\u521b\u6297\u4f53\u4e3a\u57fa\u77f3\u7684\u65b0\u578b\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u3002\u501f\u529b\u4e8e\u8ba1\u7b97\u751f\u7269\u5b66\u4e0e\u4eba\u5de5\u667a\u80fd\uff0c\u51ed\u501f\u5176\u5168\u7403\u9996\u521b\u7684\u4e09\u4f53\u5e73\u53f0\u6280\u672f\uff08\u65b0\u8868\u4f4d\u6297\u4f53NEObody™\uff0c\u5b89\u5168\u6297\u4f53SAFEbody®\u53ca\u5f3a\u529b\u6297\u4f53POWERbody™\uff09\uff0c\u5929\u6f14\u836f\u4e1a\u5df2\u5efa\u7acb\u8d77\u805a\u7126\u4e8e\u65b0\u578b\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u72ec\u7279\u539f\u521b\u7684\u6297\u4f53\u4ea7\u54c1\u7ebf\uff0c\u4ee5\u89e3\u51b3\u5c1a\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002\u5929\u6f14\u5df2\u548c\u591a\u4e2a\u5168\u7403\u77e5\u540d\u5408\u4f5c\u4f19\u4f34\u8fbe\u6210\u4e86\u6218\u7565\u5408\u4f5c\u5173\u7cfb\uff0c\u5e76\u4ee5\u5176\u591a\u79cd\u539f\u521b\u524d\u6cbf\u79d1\u6280\u4e3a\u5408\u4f5c\u4f19\u4f34\u7684\u65b0\u836f\u7814\u53d1\u8d4b\u80fd\u3002<\/p>\n

\u5982\u9700\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1a https:\/\/investor.adagene.com<\/a><\/u>.\u5e76\u5173\u6ce8\u5929\u6f14\u836f\u4e1a\u5fae\u4fe1<\/a><\/u>\u3001\u9886\u82f1<\/a><\/u>\u53ca\u63a8\u7279<\/a><\/u>\u5b98\u65b9\u8d26\u53f7\u3002<\/p>\n

SAFEbody®<\/sup> \u4e3a\u5929\u6f14\u5728\u7f8e\u56fd\u3001\u4e2d\u56fd\u3001\u6fb3\u5927\u5229\u4e9a\u3001\u65e5\u672c\u3001\u65b0\u52a0\u5761\u548c\u6b27\u76df\u7684\u6ce8\u518c\u5546\u6807\u3002<\/p>\n

\u5b89\u5168\u6e2f\u58f0\u660e<\/b><\/p>\n

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\u4e2d\u56fd\u82cf\u5dde\u548c\u7f8e\u56fd\u5723\u5730\u4e9a\u54e52024\u5e747\u670815\u65e5 \/\u7f8e\u901a\u793e\/ — \u5929\u6f14\u836f\u4e1a\uff08\u4ee5\u4e0b\u7b80\u79f0"\u516c\u53f8"\u6216"\u5929\u6f14"\uff09\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aADAG\uff09\u662f\u4e00\u5bb6\u81f4\u529b\u4e8e\u53d1\u73b0\u5e76\u5f00\u53d1\u4ee5\u539f\u521b\u6297\u4f53\u4e3a\u57fa\u77f3\u7684\u65b0\u578b\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u751f\u7269\u5236\u836f\u4f01\u4e1a\uff0c\u516c\u53f8\u4eca\u65e5\u5ba3\u5e03\uff0c\u5c06\u57282024\u5e749\u670813\u65e5\u81f317\u65e5\u4e8e\u897f\u73ed\u7259\u5df4\u585e\u7f57\u90a3\u4e3e\u529e\u7684\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\u5927\u4f1a (ESMO) \u4e0a\u8fdb\u884c\u6d77\u62a5\u5c55\u793a\u3002 \u6d77\u62a5\u5c06\u516c\u5e03\u6297CTLA-4\u5b89\u5168\u6297\u4f53ADG126\u8054\u5408\u6297PD-1\u836f\u7269\u5e15\u535a\u5229\u73e0\u5355\u6297 (Pembrolizumab) \u7684 1b\/2 \u671f\u7814\u7a76\u7ed3\u679c\u3002\u6d77\u62a5\u6807\u9898\u4e3a\uff1a \u6297CTLA-4 SAFEbody®\u5b89\u5168\u6297\u4f53ADG126 (Muzastotug, Muza) \u4e0e \u5e15\u535a\u5229\u73e0\u5355\u6297 (Pembrolizumab) \u8054\u7528\u663e\u8457\u63d0\u9ad8\u4e86\u6cbb\u7597\u6307\u6570\uff0c\u4e8e\u8f6c\u79fb\u6027\u5fae\u536b\u661f\u7a33\u5b9a\u578b\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u4e2d\u89c2\u5bdf\u5230\u7684\u4e34\u5e8a\u83b7\u76ca\u652f\u6301\u8fdb\u4e00\u6b65\u4e34\u5e8a\u5f00\u53d1 \u66f4\u591a\u8be6\u60c5\uff0c\u53ef\u5728\u53d1\u5e03\u540e\u767b\u9646\u516c\u53f8\u5b98\u65b9\u7f51\u7ad9\u7684\u53d1\u8868\u6587\u732e\u9875\u9762\u67e5\u9605\u76f8\u5173\u6d77\u62a5\u3002 \u5173\u4e8e\u5929\u6f14\u836f\u4e1a 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