{"id":113477,"date":"2024-07-04T09:16:00","date_gmt":"2024-07-04T02:16:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/20240704091600113477"},"modified":"2024-07-05T03:55:15","modified_gmt":"2024-07-04T19:55:15","slug":"%e5%92%8c%e9%bb%84%e5%8c%bb%e8%8d%af%e5%ae%a3%e5%b8%83%e4%bb%96%e6%b3%bd%e5%8f%b8%e4%bb%96-tazemetostat-%e7%94%a8%e4%ba%8e%e6%b2%bb%e7%96%97%e5%a4%8d%e5%8f%91%e6%88%96%e9%9a%be%e6%b2%bb%e6%80%a7","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/20240704091600113477","title":{"rendered":"\u548c\u9ec4\u533b\u836f\u5ba3\u5e03\u4ed6\u6cfd\u53f8\u4ed6 (tazemetostat) \u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\u7684\u4e2d\u56fd\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u83b7\u53d7\u7406\u5e76\u83b7\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4"},"content":{"rendered":"<table border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" 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href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT05467943\" target=\"_blank\" rel=\"nofollow noopener\">NCT05467943<\/a>\uff09\u3002<\/p>\n<p>\u548c\u9ec4\u533b\u836f\u6b63\u53c2\u4e0e\u76ca\u666e\u751f\u7684SYMPHONY-1\u7814\u7a76\uff0c\u5e76\u9886\u5bfc\u5728\u4e2d\u56fd\u8fdb\u884c\u7684\u7814\u7a76\u3002\u8fd9\u662f\u4e00\u9879\u591a\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u6d3b\u6027\u5bf9\u7167\u3001\u4e09\u9636\u6bb5\u3001\u751f\u7269\u6807\u5fd7\u7269\u5bcc\u96c6\u7684\u786e\u8bc1\u6027\u5168\u7403Ib\/III\u671f\u7814\u7a76\uff0c\u65e8\u5728\u8bc4\u4f30\u4ed6\u6cfd\u53f8\u4ed6\u8054\u5408\u5229\u59a5\u6614\u5355\u6297\u548c\u6765\u90a3\u5ea6\u80fa\uff08rituximab \u548clenalidomide\uff0c&nbsp;R&sup2;\u65b9\u6848\uff09\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u7ebf\u6cbb\u7597\u540e\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\u60a3\u8005\u7684\u5b89\u5168\u6027\u548c\u7597\u6548\uff08<a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04224493\" target=\"_blank\" rel=\"nofollow noopener\">NCT04224493<\/a>\uff09\u3002<\/p>\n<p><b>\u5173\u4e8e\u4ed6\u6cfd\u53f8\u4ed6\u5728\u7f8e\u56fd\u83b7\u6279<\/b><\/p>\n<p>\u4ed6\u6cfd\u53f8\u4ed6\u662f\u4e00\u79cd\u7532\u57fa\u8f6c\u79fb\u9176\u6291\u5236\u5242\uff0c\u5728\u7f8e\u56fd\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u4ee5\u4e0b\u60a3\u8005\uff1a<\/p>\n<ul 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href=\"https:\/\/d2rkmuse97gwnh.cloudfront.net\/a88aa6d6-3ca0-4362-a711-d53c45ae33ff\/522a2033-f01b-422d-81b6-78692eb7a6da\/522a2033-f01b-422d-81b6-78692eb7a6da_source__v.pdf\" target=\"_blank\" rel=\"nofollow noopener\">\u7f8e\u56fd\u5b8c\u6574\u5904\u65b9\u8d44\u6599<\/a>\u3002<\/p>\n<p>\u8fbe\u552f\u73c2&reg;\u5df2\u4e8e\u65e5\u672c\u83b7\u6279\u7528\u4e8e\u6cbb\u7597EZH2\u57fa\u56e0\u7a81\u53d8\u9633\u6027\u7684\u590d\u53d1\u6216\u96be\u6cbb\u6027\u6ee4\u6ce1\u6027\u6dcb\u5df4\u7624\uff08\u4ec5\u5f53\u6807\u51c6\u6cbb\u7597\u4e0d\u9002\u7528\u65f6\uff09\u3002<\/p>\n<p>\u8fbe\u552f\u73c2&reg;\u662f\u76ca\u666e\u751f\u65d7\u4e0b\u516c\u53f8Epizyme Inc. \u7684\u6ce8\u518c\u5546\u6807\u3002<\/p>\n<p><b>\u5173\u4e8e\u548c\u9ec4\u533b\u836f<\/b><\/p>\n<p>\u548c\u9ec4\u533b\u836f\uff08\u7eb3\u65af\u8fbe\u514b\/\u4f26\u6566\u8bc1\u4ea4\u6240\uff1aHCM\uff1b\u9999\u6e2f\u4ea4\u6613\u6240\uff1a13\uff09\u662f\u4e00\u5bb6\u5904\u4e8e\u5546\u4e1a\u5316\u9636\u6bb5\u7684\u521b\u65b0\u578b\u751f\u7269\u533b\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u53d1\u73b0\u3001\u5168\u7403\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u6cbb\u7597\u764c\u75c7\u548c\u514d\u75ab\u6027\u75be\u75c5\u7684\u9776\u5411\u836f\u7269\u548c\u514d\u75ab\u7597\u6cd5\u3002\u96c6\u56e2\u65d7\u4e0b\u516c\u53f8\u5171\u6709\u7ea65,000\u540d\u5458\u5de5\uff0c\u5176\u4e2d\u6838\u5fc3\u7684\u80bf\u7624\/\u514d\u75ab\u4e1a\u52a1\u62e5\u6709\u7ea61,800\u4eba\u7684\u56e2\u961f\u3002\u81ea\u6210\u7acb\u4ee5\u6765\uff0c\u548c\u9ec4\u533b\u836f\u81f4\u529b\u4e8e\u5c06\u81ea\u4e3b\u53d1\u73b0\u7684\u6297\u80bf\u7624\u5019\u9009\u836f\u7269\u5e26\u5411\u5168\u7403\u60a3\u8005\uff0c\u9996\u4e09\u4e2a\u836f\u7269\u73b0\u5df2\u5728\u4e2d\u56fd\u4e0a\u5e02\uff0c\u5176\u4e2d\u9996\u4e2a\u836f\u7269\u4ea6\u4e8e\u7f8e\u56fd\u4e0a\u5e02\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u8be6\u60c5\uff0c\u8bf7\u8bbf\u95ee\uff1a<a href=\"https:\/\/www.hutch-med.com\/sc\" target=\"_blank\" rel=\"nofollow noopener\">www.hutch\u2011med.com<\/a>\u6216\u5173\u6ce8\u6211\u4eec\u7684<a href=\"https:\/\/www.linkedin.com\/company\/hutchmed\/\" target=\"_blank\" rel=\"nofollow noopener\">\u9886\u82f1<\/a>\u4e13\u9875\u3002<\/p>\n<p><i><b>\u524d\u77bb\u6027\u9648\u8ff0<\/b><\/i><\/p>\n<p><i>\u672c\u65b0<\/i><i>\u95fb<\/i><i>\u7a3f\u5305\u542b<\/i><i>1995<\/i><i>\u5e74\u300a\u7f8e\u56fd\u79c1\u4eba<\/i><i>\u8bc1<\/i><i>\u5238<\/i><i>\u8bc9\u8bbc<\/i><i>\u6539\u9769\u6cd5\u6848\u300b&quot;\u5b89\u5168\u6e2f&quot;\u6761\u6b3e\u4e2d\u5b9a<\/i><i>\u4e49<\/i><i>\u7684\u524d\u77bb\u6027<\/i><i>\u9648<\/i><i>\u8ff0\u3002<\/i><i>\u8fd9<\/i><i>\u4e9b\u524d\u77bb\u6027<\/i><i>\u9648<\/i><i>\u8ff0\u53cd\u6620\u4e86\u548c\u9ec4\u533b<\/i><i>\u836f<\/i><i>\u76ee\u524d<\/i><i>\u5bf9<\/i><i>\u672a\u6765\u4e8b\u4ef6\u7684<\/i><i>\u9884<\/i><i>\u671f\uff0c\u5305\u62ec<\/i><i>\u5bf9<\/i><i>\u56fd\u5bb6<\/i><i>\u836f\u76d1<\/i><i>\u5c40<\/i><i>\u5ba1\u8bc4<\/i><i>\u4ed6<\/i><i>\u6cfd<\/i><i>\u53f8\u4ed6\u7528\u4e8e\u6cbb<\/i><i>\u7597\u6ee4<\/i><i>\u6ce1\u6027\u6dcb\u5df4\u7624\u7684\u65b0<\/i><i>\u836f<\/i><i>\u4e0a\u5e02\u7533<\/i><i>\u8bf7<\/i><i>\u4ee5\u53ca<\/i><i>\u5ba1\u8bc4\u65f6\u95f4<\/i><i>\u7684<\/i><i>\u9884<\/i><i>\u671f\u3001<\/i><i>\u4ed6<\/i><i>\u6cfd<\/i><i>\u53f8\u4ed6\u7528\u4e8e\u6cbb<\/i><i>\u7597\u6ee4<\/i><i>\u6ce1\u6027\u6dcb\u5df4\u7624\u7684\u6cbb<\/i><i>\u7597<\/i><i>\u6f5c\u529b\u7684<\/i><i>\u9884<\/i><i>\u671f\uff0c\u4ee5\u53ca\u4ed6<\/i><i>\u6cfd<\/i><i>\u53f8<\/i><i>\u4ed6<\/i><i>\u9488\u5bf9<\/i><i>\u6b64\u9002<\/i><i>\u5e94<\/i><i>\u75c7\u53ca\u5176\u4ed6\u9002<\/i><i>\u5e94<\/i><i>\u75c7\u7684<\/i><i>\u8fdb<\/i><i>\u4e00\u6b65<\/i><i>\u4e34<\/i><i>\u5e8a\u7814\u7a76<\/i><i>\u8ba1<\/i><i>\u5212\u3002<\/i><i>\u524d\u77bb\u6027<\/i><i>\u9648<\/i><i>\u8ff0\u6d89\u53ca<\/i><i>\u98ce\u9669<\/i><i>\u548c\u4e0d\u786e\u5b9a\u6027\u3002<\/i><i>\u6b64\u7c7b<\/i><i>\u98ce\u9669<\/i><i>\u548c\u4e0d\u786e\u5b9a\u6027\u5305\u62ec\u4e0b\u5217\u5047<\/i><i>\u8bbe<\/i><i>\uff1a<\/i><i>\u5bf9<\/i><i>\u7814\u7a76<\/i><i>\u65f6\u95f4<\/i><i>\u548c<\/i><i>\u7ed3<\/i><i>\u679c<\/i><i>\u53d1<\/i><i>\u5e03\u7684<\/i><i>\u9884<\/i><i>\u671f\u3001\u652f\u6301\u4ed6<\/i><i>\u6cfd<\/i><i>\u53f8\u4ed6\u5728\u4e2d\u56fd\u6216\u5176\u4ed6\u5730\u533a<\/i><i>\u83b7<\/i><i>\u6279<\/i><i>\u7528\u4e8e\u6cbb<\/i><i>\u7597\u6ee4<\/i><i>\u6ce1\u6027\u6dcb\u5df4\u7624\u7684\u65b0<\/i><i>\u836f<\/i><i>\u4e0a\u5e02\u7533<\/i><i>\u8bf7<\/i><i>\u7684\u6570\u636e\u5145\u8db3\u6027\u3001<\/i><i>\u83b7<\/i><i>\u5f97<\/i><i>\u76d1<\/i><i>\u7ba1\u90e8\u95e8\u5feb\u901f<\/i><i>\u5ba1<\/i><i>\u6279\u6216<\/i><i>\u5ba1<\/i><i>\u6279\u7684\u6f5c\u529b\uff0c\u4ed6<\/i><i>\u6cfd<\/i><i>\u53f8\u4ed6\u7684\u5b89\u5168\u6027\u3001\u548c\u9ec4\u533b<\/i><i>\u836f\u4e3a<\/i><i>\u4ed6<\/i><i>\u6cfd<\/i><i>\u53f8\u4ed6<\/i><i>\u8fdb<\/i><i>\u4e00\u6b65<\/i><i>\u4e34<\/i><i>\u5e8a\u5f00<\/i><i>\u53d1\u8ba1<\/i><i>\u5212\u53ca\u5546<\/i><i>\u4e1a<\/i><i>\u5316\u63d0\u4f9b<\/i><i>\u8d44<\/i><i>\u91d1\u5e76<\/i><i>\u5b9e\u73b0<\/i><i>\u53ca\u5b8c\u6210\u7684\u80fd\u529b\uff0c\u4ee5\u53ca\u6b64\u7c7b\u4e8b\u4ef6<\/i><i>\u53d1<\/i><i>\u751f\u7684<\/i><i>\u65f6\u95f4<\/i><i>\u7b49<\/i><i>\u3002\u5f53\u524d\u548c\u6f5c\u5728\u6295<\/i><i>\u8d44<\/i><i>\u8005<\/i><i>\u8bf7<\/i><i>\u52ff<\/i><i>\u8fc7<\/i><i>\u5ea6\u4f9d<\/i><i>\u8d56\u8fd9<\/i><i>\u4e9b\u524d\u77bb\u6027<\/i><i>\u9648<\/i><i>\u8ff0\uff0c<\/i><i>\u8fd9<\/i><i>\u4e9b<\/i><i>\u9648<\/i><i>\u8ff0<\/i><i>\u4ec5<\/i><i>\u5728\u622a\u81f3\u672c\u65b0<\/i><i>\u95fb<\/i><i>\u7a3f<\/i><i>\u53d1<\/i><i>\u5e03\u5f53\u65e5\u6709\u6548\u3002<\/i><i>\u6709\u5173<\/i><i>\u8fd9<\/i><i>\u4e9b<\/i><i>\u98ce\u9669<\/i><i>\u548c\u5176\u4ed6<\/i><i>\u98ce\u9669<\/i><i>\u7684<\/i><i>\u8fdb<\/i><i>\u4e00\u6b65<\/i><i>\u8ba8\u8bba<\/i><i>\uff0c<\/i><i>\u8bf7\u67e5\u9605<\/i><i>\u548c\u9ec4\u533b<\/i><i>\u836f<\/i><i>\u5411\u7f8e\u56fd<\/i><i>\u8bc1<\/i><i>\u5238\u4ea4<\/i><i>\u6613\u59d4<\/i><i>\u5458<\/i><i>\u4f1a\u3001\u9999\u6e2f<\/i><i>\u8054<\/i><i>\u5408\u4ea4\u6613\u6240\u6709\u9650\u516c\u53f8\u4ee5\u53ca<\/i><i>AIM<\/i><i>\u63d0\u4ea4\u7684\u6587\u4ef6\u3002\u65e0<\/i><i>\u8bba<\/i><i>\u662f\u5426\u51fa<\/i><i>\u73b0<\/i><i>\u65b0<\/i><i>\u8baf<\/i><i>\u606f\u3001\u672a\u6765\u4e8b\u4ef6\u6216\u60c5\u51b5\u6216\u5176\u4ed6\u56e0\u7d20\uff0c\u548c\u9ec4\u533b<\/i><i>\u836f<\/i><i>\u5747\u4e0d\u627f\u62c5\u66f4\u65b0\u6216\u4fee<\/i><i>\u8ba2<\/i><i>\u672c\u65b0<\/i><i>\u95fb<\/i><i>\u7a3f\u6240\u542b<\/i><i>\u8baf<\/i><i>\u606f\u7684<\/i><i>\u4e49\u52a1<\/i><i>\u3002<\/i><\/p>\n<p><b><i>\u533b\u7597\u4fe1\u606f<\/i><\/b><\/p>\n<p><i>\u672c\u65b0<\/i><i>\u95fb<\/i><i>\u7a3f\u6240\u63d0<\/i><i>\u5230\u7684<\/i><i>\u4ea7<\/i><i>\u54c1\u53ef\u80fd\u5e76\u672a\u5728\u6240\u6709\u56fd\u5bb6\u4e0a\u5e02\uff0c\u6216\u53ef\u80fd\u4ee5\u4e0d\u540c\u7684\u5546<\/i><i>\u6807\u8fdb<\/i><i>\u884c<\/i><i>\u9500<\/i><i>\u552e\uff0c\u6216\u7528\u4e8e\u4e0d\u540c\u7684\u75c5\u75c7\uff0c\u6216\u91c7\u7528\u4e0d\u540c\u7684<\/i><i>\u5242<\/i><i>\u91cf\uff0c\u6216<\/i><i>\u62e5<\/i><i>\u6709\u4e0d\u540c\u7684\u6548\u529b<\/i><i>\u3002\u672c\u6587\u4e2d\u6240\u5305\u542b\u7684\u4efb\u4f55\u4fe1\u606f\u90fd\u4e0d<\/i><i>\u5e94<\/i><i>\u88ab\u770b\u4f5c\u662f\u4efb\u4f55<\/i><i>\u5904<\/i><i>\u65b9<\/i><i>\u836f<\/i><i>\u7684\u7533<\/i><i>\u8bf7<\/i><i>\u3001\u63a8\u5e7f\u6216\u5e7f\u544a\uff0c\u5305\u62ec\u90a3\u4e9b\u6b63\u5728\u7814<\/i><i>\u53d1<\/i><i>\u7684<\/i><i>\u836f<\/i><i>\u7269\u3002<\/i><\/p>\n[1] Source: NCCN \u2013&nbsp;<a href=\"https:\/\/www.nccn.org\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.nccn.org<\/a><br \/>[2]&nbsp;Source: SEER \u2013 <a href=\"https:\/\/seer.cancer.gov\/statfacts\/html\/follicular.html\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/seer.cancer.gov\/statfacts\/html\/follicular.html<\/a><br \/>[3]&nbsp;Source: GLOBOCAN <a href=\"https:\/\/gco.iarc.fr\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/gco.iarc.fr\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u9999\u6e2f\u3001\u4e0a\u6d77\u548c\u65b0\u6cfd\u897f\u5dde\u5f17\u6d1b\u52d2\u59c6\u516c\u56ed2024\u5e747\u67084\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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\u533b\u7597\u4fe1\u606f \u672c\u65b0\u95fb\u7a3f\u6240\u63d0\u5230\u7684\u4ea7\u54c1\u53ef\u80fd\u5e76\u672a\u5728\u6240\u6709\u56fd\u5bb6\u4e0a\u5e02\uff0c\u6216\u53ef\u80fd\u4ee5\u4e0d\u540c\u7684\u5546\u6807\u8fdb\u884c\u9500\u552e\uff0c\u6216\u7528\u4e8e\u4e0d\u540c\u7684\u75c5\u75c7\uff0c\u6216\u91c7\u7528\u4e0d\u540c\u7684\u5242\u91cf\uff0c\u6216\u62e5\u6709\u4e0d\u540c\u7684\u6548\u529b\u3002\u672c\u6587\u4e2d\u6240\u5305\u542b\u7684\u4efb\u4f55\u4fe1\u606f\u90fd\u4e0d\u5e94\u88ab\u770b\u4f5c\u662f\u4efb\u4f55\u5904\u65b9\u836f\u7684\u7533\u8bf7\u3001\u63a8\u5e7f\u6216\u5e7f\u544a\uff0c\u5305\u62ec\u90a3\u4e9b\u6b63\u5728\u7814\u53d1\u7684\u836f\u7269\u3002 [1] Source: NCCN \u2013&nbsp;https:\/\/www.nccn.org[2]&nbsp;Source: SEER \u2013 https:\/\/seer.cancer.gov\/statfacts\/html\/follicular.html[3]&nbsp;Source: GLOBOCAN https:\/\/gco.iarc.fr\/&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/20240704091600113477\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":113480,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-113477","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/113477","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=113477"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/113477\/revisions"}],"predecessor-version":[{"id":113479,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/113477\/revisions\/113479"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media\/113480"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=113477"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=113477"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=113477"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}