{"id":113045,"date":"2024-04-30T13:04:00","date_gmt":"2024-04-30T06:04:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/20240430130400113045"},"modified":"2024-05-01T00:27:08","modified_gmt":"2024-04-30T16:27:08","slug":"%e5%85%a8%e7%90%83%e9%a6%96%e5%88%9b%e5%bf%83%e8%82%8c%e8%82%8c%e7%90%83%e8%9b%8b%e7%99%bd%e6%8a%91%e5%88%b6%e5%89%82%e8%bf%88%e5%87%a1%e5%a6%a5%ef%bc%88%e7%8e%9b%e4%bc%90%e5%87%af%e6%b3%b0","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/20240430130400113045","title":{"rendered":"\u5168\u7403\u9996\u521b\u5fc3\u808c\u808c\u7403\u86cb\u767d\u6291\u5236\u5242\u8fc8\u51e1\u59a5\u00ae\uff08\u739b\u4f10\u51ef\u6cf0\u80f6\u56ca\uff09\u5728\u4e2d\u56fd\u83b7\u6279"},"content":{"rendered":"<p class=\"prntac\"><b><span id=\"spanHghlt2e36\">\u7528\u4e8e\u6cbb\u7597\u6897\u963b\u6027\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u6210\u4eba\u60a3\u8005<\/span><\/b><\/p>\n<ul 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id=\"spanHghltb9c8\">[1]<\/span><\/sup>\u4e2d\u53ef\u663e\u8457\u6539\u5584\u9759\u606f\u6216Valsalva\u6fc0\u53d1\u4e0b\u5de6\u5fc3\u5ba4\u6d41\u51fa\u9053\uff08LVOT\uff09\u538b\u5dee\u3001\u7ebd\u7ea6\u5fc3\u810f\u534f\u4f1a\uff08NYHA\uff09\u5fc3\u529f\u80fd\u5206\u7ea7\uff0c\u5e76\u6539\u5584\u60a3\u8005\u8fd0\u52a8\u80fd\u529b\u548c\u751f\u6d3b\u8d28\u91cf<\/i><\/li>\n<li><i>\u83b7<\/i><i>FDA\u548cCDE\u6388\u4e88\u6cbb\u7597oHCM<sup><span id=\"spanHghlt9766\"> [<\/span><\/sup><\/i><i><sup><span id=\"spanHghltc3a2\">1]<\/span><\/sup><\/i><i>&quot;\u7a81\u7834\u6027\u6cbb\u7597\u836f\u7269&quot;\u8d44\u683c\u8ba4\u8bc1\uff0c\u8363\u81ba2023\u5e74\u7f8e\u56fd\u76d6\u4f26\u5956&quot;\u6700\u4f73\u751f\u7269\u6280\u672f\u4ea7\u54c1\u5956&quot;\uff0c\u6253\u7834\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u56db\u5341\u4f59\u5e74\u6cbb\u7597\u56f0\u5c40<\/i><\/li>\n<\/ul>\n<p><p><span class=\"legendSpanClass\">\u4e0a\u6d77<\/span><span class=\"legendSpanClass\">2024\u5e744\u670830\u65e5<\/span> 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\u5de6\u5fc3\u5ba4\u6d41\u51fa\u9053\uff08LVOT\uff09\u5cf0\u503c\u538b\u5dee\u4e0a\u8868\u73b0\u51fa\u663e\u8457\u6539\u5584\uff0c\u540c\u65f6\u5728\u5305\u62ecLVOT\u6897\u963b\u3001\u4e34\u5e8a\u75c7\u72b6\u3001\u5065\u5eb7\u72b6\u6001\u3001\u5fc3\u810f\u751f\u7269\u6807\u5fd7\u7269\u53ca\u5fc3\u810f\u7ed3\u6784\u5728\u5185\u7684\u6240\u6709\u6b21\u8981\u7ec8\u70b9\u4e2d\u5747\u89c2\u5bdf\u5230\u6539\u5584\u3002\u5728\u5b89\u5168\u6027\u65b9\u9762\uff0c\u8fc8\u51e1\u59a5<sup>&reg;<\/sup>\u5728\u4e2d\u56fd\u6897\u963b\u6027HCM\u60a3\u8005\u4e2d\u8010\u53d7\u6027\u826f\u597d\uff0c\u5e76\u8868\u73b0\u51fa\u4e0e\u65e2\u5f80\u7814\u7a76\u4e00\u81f4\u7684\u5b89\u5168\u6027\u7279\u5f81\u3002<\/p>\n<p><b>\u5f20\u6292\u626c\u6559\u6388<\/b>\u8868\u793a\uff1a&quot;\u739b\u4f10\u51ef\u6cf0\u662f\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u6cbb\u7597\u9886\u57df\u7684\u521b\u65b0\u6cbb\u7597\u836f\u7269\uff0c\u5df2\u5728\u591a\u9879\u56fd\u9645\u7814\u7a76\u4e2d\u8bc1\u5b9e\u4e86\u7597\u6548\u548c\u5b89\u5168\u6027\uff0c\u800c\u9488\u5bf9\u4e2d\u56fd\u60a3\u8005\u5f00\u5c55\u7684EXPLORER-CN\u7814\u7a76\u4e5f\u8bc1\u5b9e\u4e86\u739b\u4f10\u51ef\u6cf0\u80fd\u591f\u4e3a\u4e2d\u56fd\u60a3\u8005\u5e26\u6765\u663e\u8457\u83b7\u76ca\u3002\u739b\u4f10\u51ef\u6cf0\u5728\u4e2d\u56fd\u7684\u83b7\u6279\u5f00\u542f\u4e86\u4e2d\u56fd\u6897\u963b\u6027HCM\u6cbb\u7597\u7684\u65b0\u7eaa\u5143\uff0c\u6709\u671b\u91cd\u65b0\u5b9a\u4e49\u6b64\u7c7b\u60a3\u8005\u7684\u6cbb\u7597\u524d\u666f\u3002&quot;<\/p>\n<p>2022\u5e74\uff0c\u8fc8\u51e1\u59a5<sup>&reg;<\/sup>\u83b7\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u6388\u4e88&quot;\u7a81\u7834\u6027\u6cbb\u7597\u836f\u7269&quot;\u8d44\u683c\u8ba4\u8bc1\u5e76\u4e8e\u6b21\u5e74\u5c06\u5176\u7eb3\u5165\u4e86\u4f18\u5148\u5ba1\u8bc4\u30022023\u5e7410\u6708\uff0c\u8fc8\u51e1\u59a5<sup>&reg;<\/sup>\u56e0\u5176\u521b\u65b0\u7684\u673a\u5236\u5728\u7f8e\u56fd\u6458\u5f97\u4eab\u6709\u533b\u7597\u754c&quot;\u8bfa\u8d1d\u5c14\u5956&quot;\u4e4b\u79f0\u7684\u76d6\u4f26\u5956 &quot;\u6700\u4f73\u751f\u7269\u6280\u672f\u4ea7\u54c1\u5956&quot;\u3002\u76ee\u524d\uff0c\u8fc8\u51e1\u59a5<sup>&reg;<\/sup>\u5df2\u88ab\u7eb3\u5165\u300a2023\u6b27\u6d32\u5fc3\u810f\u75c5\u5b66\u4f1a\uff08ESC\uff09\u5fc3\u808c\u75c5\u7ba1\u7406\u6307\u5357\u300b<sup>[8]<\/sup>\u3001\u300a\u4e2d\u56fd\u6210\u4eba\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u8bca\u65ad\u4e0e\u6cbb\u7597\u6307\u53572023\u300b<sup>[9]<\/sup> \u4ee5\u53ca\u300a\u4e2d\u56fd\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u6307\u53572022\u300b<sup>[10]<\/sup>\uff0c\u4f5c\u4e3a\u6897\u963b\u6027\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u60a3\u8005\u7684\u63a8\u8350\u7597\u6cd5\u4e4b\u4e00\u3002<\/p>\n<p><b>\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u526f\u603b\u88c1\u3001\u4e2d\u56fd\u53ca\u4e9a\u6d32\u533a\u57df\u5e02\u573a\u603b\u7ecf\u7406\u3001\u4e2d\u56fd\u533a\u603b\u88c1\u9648\u601d\u6e0a\u5973\u58eb<\/b>\u8868\u793a\uff0c&quot;\u4e2d\u56fd\u5bf9\u521b\u65b0\u836f\u7269\u51c6\u5165\u7684\u652f\u6301\u529b\u5ea6\u6b63\u5728\u4e0d\u65ad\u52a0\u5927\uff0c\u4f5c\u4e3a\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u2018\u4e2d\u56fd2030\u6218\u7565&#8217;\u5b9e\u65bd\u4ee5\u6765\u5728\u5fc3\u8840\u7ba1\u9886\u57df\u83b7\u6279\u7684\u7b2c\u4e00\u4e2a\u521b\u65b0\u836f\u7269\uff0c\u8fc8\u51e1\u59a5<sup>&reg;<\/sup>\u6b64\u524d\u5df2\u5728\u6fb3\u95e8\u548c\u9999\u6e2f\u83b7\u6279\uff0c\u5e76\u4e8e\u4eca\u5e74\u5e74\u521d\u6b63\u5f0f\u843d\u5730\u6d77\u5357\u535a\u9ccc\u2018\u533b\u7597\u7279\u533a&#8217;\u3002\u6b64\u6b21\u5728\u4e2d\u56fd\u5927\u9646\u7684\u83b7\u6279\u5c06\u6709\u671b\u4e3a\u66f4\u591a\u7684\u6897\u963b\u6027\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u60a3\u8005\u5e26\u6765\u5168\u65b0\u6cbb\u7597\u9009\u62e9\uff0c\u63d0\u9ad8\u60a3\u8005\u751f\u6d3b\u8d28\u91cf\u3002\u76ee\u524d\u6211\u4eec\u6b63\u79ef\u6781\u4e0e\u76d1\u7ba1\u673a\u6784\u534f\u4f5c\uff0c\u52a0\u901f\u63a8\u52a8\u836f\u7269\u5728\u4e2d\u56fd\u7684\u53ef\u53ca\uff0c\u4ee5\u671f\u8ba9\u60a3\u8005\u65e9\u65e5\u83b7\u76ca\uff0c\u8fc8\u5411\u6cf0\u7136\u751f\u6d3b\u3002&quot;<\/p>\n<p><i>\u672c\u6750\u6599\u975e\u63a8\u5e7f\u7528\u9014\uff0c\u5982\u82e5\u60f3\u4e86\u89e3\u66f4\u591a\u533b\u5b66\u4e13\u4e1a\u4fe1\u606f\uff0c\u8bf7\u54a8\u8be2\u533b\u7597\u536b\u751f\u4e13\u4e1a\u4eba\u58eb\u3002<\/i><\/p>\n<p><b><u>\u5173\u4e8e\u80a5\u539a\u578b\u5fc3\u808c\u75c5<\/u><\/b><\/p>\n<p>\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u4e3b\u8981\u662f\u7531\u4e8e\u7f16\u7801\u808c\u5c0f\u8282\u76f8\u5173\u86cb\u767d\u57fa\u56e0\u81f4\u75c5\u6027\u53d8\u5f02\u5bfc\u81f4\u7684\uff0c\u6216\u75c5\u56e0\u4e0d\u660e\u7684\u4ee5\u5fc3\u808c\u80a5\u539a\u4e3a\u7279\u5f81\u7684\u5fc3\u808c\u75c5\uff0c\u5de6\u5fc3\u5ba4\u58c1\u53d7\u7d2f\u5e38\u89c1\uff0c\u9700\u6392\u9664\u5176\u4ed6\u7684\u5fc3\u8840\u7ba1\u75be\u75c5\u6216\u5168\u8eab\u6027\u3001\u4ee3\u8c22\u6027\u75be\u75c5\u5f15\u8d77\u7684\u5fc3\u5ba4\u58c1\u589e\u539a\u3002\u636e\u4f30\u7b97\uff0c\u6211\u56fd\u7ecf\u5e74\u9f84\u548c\u6027\u522b\u6821\u6b63\u540e\u7684\u60a3\u75c5\u7387\u7ea6\u4e3a80\/10\u4e07<sup>[4]<\/sup>\u3002\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u4e0e\u623f\u98a4\u3001\u5352\u4e2d\u3001\u5fc3\u529b\u8870\u7aed\u548c\u5fc3\u810f\u6027\u731d\u6b7b\u98ce\u9669\u7684\u589e\u52a0\u6709\u5173\u3002<\/p>\n<p>HCM\u6839\u636e\u662f\u5426\u5b58\u5728\u5de6\u5fc3\u5ba4\u6d41\u51fa\u9053\uff08LVOT\uff09\u6897\u963b\u53ef\u5206\u4e3a\u6897\u963b\u6027\u548c\u975e\u6897\u963b\u6027\u3002\u5728\u6897\u963b\u6027\u6216\u975e\u6897\u963b\u6027\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u60a3\u8005\u4e2d\uff0c\u4f53\u529b\u6d3b\u52a8\u53ef\u5bfc\u81f4\u75b2\u52b3\u6216\u547c\u5438\u56f0\u96be\uff0c\u4e25\u91cd\u5f71\u54cd\u60a3\u8005\u7684\u65e5\u5e38\u5de5\u4f5c\u548c\u751f\u6d3b\u3002<\/p>\n<p><b><u>\u5173\u4e8e\u8fc8\u51e1\u59a5<\/u><\/b><b><u><sup>&reg;<\/sup><\/u><\/b><b><u>\uff08\u739b\u4f10\u51ef\u6cf0\u80f6\u56ca\uff09<\/u><\/b><\/p>\n<p>\u8fc8\u51e1\u59a5<sup>&reg;<\/sup>\uff08\u739b\u4f10\u51ef\u6cf0\u80f6\u56ca\uff09\u662f\u9996\u4e2a\u4e14\u76ee\u524d\u552f\u4e00\u83b7\u5f97\u6279\u51c6\u7684\u5fc3\u808c\u808c\u7403\u86cb\u767d\u6291\u5236\u5242\uff0c\u7528\u4e8e\u6cbb\u7597\u7ebd\u7ea6\u5fc3\u810f\u534f\u4f1a\uff08NYHA\uff09\u5fc3\u529f\u80fd\u5206\u7ea7II-III\u7ea7\u7684\u6897\u963b\u6027\u80a5\u539a\u578b\u5fc3\u808c\u75c5\uff08HCM\uff09\u6210\u4eba\u60a3\u8005\uff0c\u4ee5\u6539\u5584\u8fd0\u52a8\u80fd\u529b\u548c\u75c7\u72b6\u3002\u76ee\u524d\uff0c\u8be5\u836f\u5df2\u5728\u4e94\u5927\u6d32\u7684\u591a\u4e2a\u56fd\u5bb6\u548c\u5730\u533a\u83b7\u6279\u4e0a\u5e02\uff0c\u5305\u62ec\u7f8e\u56fd\u3001\u6b27\u76df\u3001\u963f\u6839\u5ef7\u3001\u6fb3\u5927\u5229\u4e9a\u3001\u5df4\u897f\u3001\u52a0\u62ff\u5927\u3001\u82f1\u56fd\u3001\u6fb3\u95e8\u3001\u9999\u6e2f\u3001\u4ee5\u8272\u5217\u3001\u65b0\u52a0\u5761\u3001\u97e9\u56fd\u548c\u745e\u58eb\u7b49\u3002\u8fc8\u51e1\u59a5<sup>&reg;<\/sup>\u662f\u4e00\u79cd\u5fc3\u808c\u808c\u7403\u86cb\u767d\u9009\u62e9\u6027\u7684\u53d8\u6784\u3001\u53ef\u9006\u6027\u6291\u5236\u5242\uff0c\u5176\u901a\u8fc7\u8c03\u8282\u80fd\u8fdb\u5165&quot;\u53ef\u7ed3\u5408\u808c\u52a8\u86cb\u767d&quot;\uff08\u4ea7\u751f\u6536\u7f29\u529b\uff09\u72b6\u6001\u7684\u808c\u7403\u86cb\u767d\u5934\u7684\u6570\u91cf\uff0c\u4ece\u800c\u51cf\u5c11\u52a8\u529b\u4ea7\u751f\uff08\u6536\u7f29\u671f\uff09\u548c\u6b8b\u7559\uff08\u8212\u5f20\u671f\uff09\u6a2a\u6865\u5f62\u6210\u7684\u6982\u7387\u3002HCM\u7684\u4e3b\u8981\u673a\u7406\u7279\u5f81\u5728\u4e8e\u8fc7\u91cf\u808c\u7403\u86cb\u767d-\u808c\u52a8\u86cb\u767d\u6a2a\u6865\u7684\u5f62\u6210\u548c\u8d85\u677e\u5f1b\u72b6\u6001\u7684\u5931\u8c03\uff0c\u8fc8\u51e1\u59a5<sup>&reg;<\/sup>\u80fd\u591f\u51cf\u5c11\u808c\u7403\u86cb\u767d-\u808c\u52a8\u86cb\u767d\u6a2a\u6865\u5f62\u6210\uff0c\u5e76\u5c06\u6574\u4f53\u808c\u7403\u86cb\u767d\u7fa4\u6709\u6548\u8f6c\u53d8\u81f3\u8282\u80fd\u4e14\u53ef\u52df\u96c6\u7684\u8d85\u677e\u5f1b\u72b6\u6001\u3002\u5bf9\u4e8eHCM\u60a3\u8005\u7684\u6cbb\u7597\uff0c\u8fc8\u51e1\u59a5<sup>&reg;<\/sup>\u6291\u5236\u5fc3\u808c\u808c\u7403\u86cb\u767d\u53ef\u51cf\u5c11\u52a8\u529b\u6027\u5de6\u5fc3\u5ba4\u6d41\u51fa\u9053\uff08LVOT\uff09\u6897\u963b\u5e76\u6539\u5584\u5fc3\u810f\u5145\u76c8\u538b\u3002<\/p>\n<p><b><u>\u5173\u4e8e<\/u><\/b><b><u>EXPLORER-CN<\/u><\/b><\/p>\n<p>EXPLORER-CN\u7814\u7a76\u662f\u4e00\u9879\u591a\u4e2d\u5fc3\u3001\u53cc\u76f2\u3001\u968f\u673a\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684\u2162\u671f\u4e34\u5e8a\u6ce8\u518c\u7814\u7a76\uff0c\u76ee\u7684\u662f\u9a8c\u8bc1<i>\u8fc8\u51e1\u59a5<\/i><i><sup>&reg;<\/sup><\/i><i>\uff08\u739b\u4f10\u51ef\u6cf0\uff09<\/i>\u5728\u4e2d\u56fd\u6897\u963b\u6027\u80a5\u539a\u578b\u5fc3\u808c\u75c5\uff08HCM\uff09\u60a3\u8005\u4e2d\u7684\u4f7f\u7528\u6548\u679c\uff0c\u4ee5\u8fdb\u4e00\u6b65\u8bc4\u4f30<i>\u8fc8\u51e1\u59a5<\/i><i><sup>&reg;<\/sup><\/i>\u5728\u4e2d\u56fd\u6897\u963b\u6027HCM\u60a3\u8005\u4e2d\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002\u7814\u7a76\u7eb3\u5165\u4e86\u4e2d\u56fd12\u5bb6\u4e2d\u5fc381\u4f8b\u6709\u75c7\u72b6\u7684\u6897\u963b\u6027HCM\u60a3\u8005\u3002\u6240\u6709\u60a3\u8005\u63092:1\u7684\u6bd4\u4f8b\u968f\u673a\u5206\u914d\u81f3<i>\u8fc8\u51e1\u59a5<\/i><i><sup>&reg;<\/sup><\/i>\u7ec4\u548c\u5b89\u6170\u5242\u7ec4\uff0c\u5728\u53cc\u76f2\u72b6\u6001\u4e0b\u63a5\u53d7<i>\u8fc8\u51e1\u59a5<\/i><i><sup>&reg;<\/sup><\/i>\u6216\u5b89\u6170\u5242\u5bf9\u7167\u6cbb\u759730\u5468\u3002\u572830\u5468\u53cc\u76f2\u5b89\u6170\u5242\u5bf9\u7167\u6cbb\u7597\u671f\u540e\uff0c\u6240\u6709\u7b26\u5408\u6761\u4ef6\u7684\u60a3\u8005\u8fdb\u5165\u5ef6\u957f\u6cbb\u7597\u671f\uff0c\u7ee7\u7eed\u63a5\u53d748\u5468\u7684<i>\u8fc8\u51e1\u59a5<\/i><i><sup>&reg;<\/sup><\/i>\u6cbb\u7597\u3002<\/p>\n<p>\u8be5\u7814\u7a76\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\u662f\u4ece\u57fa\u7ebf\u5230\u7b2c30\u5468Valsalva LVOT\u5cf0\u503c\u538b\u5dee\u7684\u53d8\u5316\u3002\u66f4\u591a\u5173\u4e8e EXPLORER-CN \u8bd5\u9a8c\u7684\u4fe1\u606f\uff0c\u53ef\u767b\u5f55ClinicalTrials.gov (NCT05174416) <a href=\"http:\/\/www.chinadrugtrials.org.cn\/index.html\" target=\"_blank\" rel=\"nofollow noopener\">http:\/\/www.chinadrugtrials.org.cn\/index.html<\/a> (CTR20212890)\u8fdb\u884c\u67e5\u8be2\u3002<\/p>\n<p><b><u>\u5173\u4e8e\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u4e2d\u56fd<\/u><\/b><\/p>\n<p>\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u662f\u4e00\u5bb6\u4ee5&quot;\u7814\u53d1\u5e76\u63d0\u4f9b\u521b\u65b0\u836f\u7269\uff0c\u5e2e\u52a9\u60a3\u8005\u6218\u80dc\u4e25\u91cd\u75be\u75c5&quot;\u4e3a\u4f7f\u547d\u7684\u5168\u7403\u9886\u5148\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u59cb\u7ec8\u8df5\u884c&quot;\u5f15\u9886\u79d1\u5b66\uff0c\u6539\u53d8\u60a3\u8005\u751f\u547d&quot;\u7684\u4f01\u4e1a\u613f\u666f\u3002\u5728\u4e2d\u56fd\uff0c\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u81f4\u529b\u4e8e\u6210\u4e3a&quot;\u6839\u690d\u4e2d\u56fd\u3001\u6e90\u4e8e\u4e2d\u56fd&quot;\u7684\u521b\u65b0\u9886\u5bfc\u8005\uff0c\u4e13\u6ce8\u4e8e\u52a0\u901f\u5f15\u8fdb\u516c\u53f8\u5728\u80bf\u7624\u5b66\u3001\u8840\u6db2\u5b66\u3001\u514d\u75ab\u5b66\u548c\u5fc3\u8840\u7ba1\u75be\u75c5\u7b49\u6838\u5fc3\u6cbb\u7597\u9886\u57df\u7684\u521b\u65b0\u836f\u7269\uff0c\u65e9\u65e5\u60e0\u53ca\u4e2d\u56fd\u60a3\u8005\u3002<\/p>\n<p>\u65b0\u57fa\u4e0e\u6731\u8bfa\u533b\u7597\u662f\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u516c\u53f8\u7684\u5168\u8d44\u5b50\u516c\u53f8\u3002\u5728\u7f8e\u56fd\u4ee5\u5916\u7684\u90e8\u5206\u5e02\u573a\uff0c\u9274\u4e8e\u5f53\u5730\u6cd5\u5f8b\uff0c\u65b0\u57fa\u548c\u6731\u8bfa\u533b\u7597\u5206\u522b\u88ab\u79f0\u4e4b\u4e3a\u65b0\u57fa\u2014\u2014\u4e00\u5bb6\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u7684\u516c\u53f8\u548c\u6731\u8bfa\u533b\u7597\u2014\u2014\u4e00\u5bb6\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u7684\u516c\u53f8\u3002<\/p>\n<p>\u5982\u9700\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u6d4f\u89c8\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u4e2d\u56fd\u5b98\u65b9\u7f51\u7ad9<a href=\"https:\/\/urldefense.proofpoint.com\/v2\/url?u=http-3A__www.bms.com.cn-25E6-2588-2596-25E6-2589-25AB-25E6-258F-258F-25E4-25BA-258C-25E7-25BB-25B4-25E7-25A0-2581-25E5-2585-25B3-25E6-25B3-25A8-25E7-2599-25BE-25E6-2597-25B6-25E7-25BE-258E-25E6-2596-25BD-25E8-25B4-25B5-25E5-25AE-259D-25E4-25B8-25AD-25E5-259B-25BD-25E5-25AE-2598-25E6-2596-25B9-25E5-25BE-25AE-25E4-25BF-25A1&amp;d=DwMGaQ&amp;c=Ftw_YSVcGmqQBvrGwAZugGylNRkk-uER0-5bY94tjsc&amp;r=LGao_coYPQpmz-mnB1Vq7iKZSZlsMdb2v9hKQgcKzf4&amp;m=iG0reKBbe8yRFXBhven_EmhVkh2ESG0Hua_WApYAdI8&amp;s=sDSYyuQY6KenzhFjas5VOq8toE4eUSVkw_KdwLzicRo&amp;e=\" target=\"_blank\" rel=\"nofollow noopener\">www.bms.com.<span id=\"spanHghlt20c4\">cn\u6216\u5173\u6ce8\u767e\u65f6<\/span>\u7f8e\u65bd\u8d35\u5b9d\u4e2d\u56fd\u5b98\u65b9\u5fae\u4fe1<\/a>\u516c\u4f17\u53f7\u53ca\u5b98\u65b9\u89c6\u9891\u53f7\u3002<\/p>\n<div>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"1\" class=\"prnbcc\">\n<tbody>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[1] <\/sup><\/span>\u7ebd\u7ea6\u5fc3\u810f\u534f\u4f1a\uff08NYHA\uff09\u5fc3\u529f\u80fd\u5206\u7ea7II-III\u7ea7\u7684\u6897\u963b\u6027\u80a5\u539a\u578b\u5fc3\u808c\u75c5\uff08HCM\uff09\u6210\u4eba\u60a3\u8005<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[2]<\/sup><\/span>&nbsp;Olivotto I, et al. Lancet 2020;396:759\u201369. \uff1bTian Z, et al. JAMA Cardiol. 2023 Oct 1;8(10):957-965.<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[3]<\/sup><\/span>&nbsp;\u56fd\u5bb6\u5fc3\u8840\u7ba1\u75c5\u4e13\u5bb6\u59d4\u5458\u4f1a\u5fc3\u529b\u8870\u7aed\u4e13\u4e1a\u59d4\u5458\u4f1a, \u4e2d\u56fd\u533b\u5e08\u534f\u4f1a\u5fc3\u529b\u8870\u7aed\u4e13\u4e1a\u59d4\u5458\u4f1a, \u4e2d\u534e\u533b\u5b66\u4f1a\u5fc3\u8840\u7ba1\u5206\u4f1a\u5fc3\u529b\u8870\u7aed\u5b66\u7ec4, \u7b49. \u4e2d\u56fd\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u6307\u5357 2022[J]. \u4e2d\u534e\u5fc3\u529b\u8870\u7aed\u548c\u5fc3\u808c\u75c5\u6742\u5fd7, 2022, 6(2): 80-105. DOI: 10.3760\/cma.j.cn1101460-20220805-00070.<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[4]<\/sup><\/span>&nbsp;Zou, Y. , Song, L. , Wang, Z. , Ma, A. , Liu, T. , Gu, H. , et al. (2004). Prevalence of idiopathic hypertrophic cardiomyopathy in China: a population-based echocardiographic analysis of 8080 adults. American Journal of Medicine, 116(1), 14-18.<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[5]<\/sup><\/span>&nbsp;Maron M, et al. Heart. 2022 Oct 21:heartjnl-2020-316693<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[6]<\/sup><\/span>&nbsp;Butzner, Michael et al. &quot;Clinical Characteristics and Healthcare Resource Utilization among Patients with Obstructive Hypertrophic Cardiomyopathy Treated in a Range of Settings in the United States.&quot;&nbsp;Journal of clinical medicine&nbsp;vol. 11,13 3898. 4 Jul. 2022<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[7]<\/sup><\/span>&nbsp;Zhuang Tian,et al. JAMA Cardiol. Published online August 28, 2023. doi:10.1001\/jamacardio.2023.3030 (https:\/\/jamanetwork.com\/journals\/jamacardiology\/fullarticle\/2809051)<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[8]<\/sup><\/span>&nbsp;Arbelo E, et al; ESC Scientific Document Group. Eur Heart J. 2023 Oct 1;44(37):3503-3626.&nbsp;<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[9]<\/sup><\/span>&nbsp;\u56fd\u5bb6\u5fc3\u8840\u7ba1\u75c5\u4e2d\u5fc3\u5fc3\u808c\u75c5\u4e13\u79d1\u8054\u76df, \u7b49. \u4e2d\u56fd\u5faa\u73af\u6742\u5fd7,2023,38(1):1-33.<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[10]<\/sup><\/span>&nbsp;\u56fd\u5bb6\u5fc3\u8840\u7ba1\u75c5\u4e13\u5bb6\u59d4\u5458\u4f1a\u5fc3\u529b\u8870\u7aed\u4e13\u4e1a\u59d4\u5458\u4f1a,\u7b49. \u4e2d\u534e\u5fc3\u529b\u8870\u7aed\u548c\u5fc3\u808c\u75c5\u6742\u5fd7, 2022, 06(2): 80-105.<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7528\u4e8e\u6cbb\u7597\u6897\u963b\u6027\u80a5\u539a\u578b\u5fc3\u808c\u75c5\u6210\u4eba\u60a3\u8005 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