{"id":110455,"date":"2024-04-10T07:41:00","date_gmt":"2024-04-10T00:41:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/20240410074100110455"},"modified":"2024-04-11T00:40:58","modified_gmt":"2024-04-10T16:40:58","slug":"her2%e5%8f%8c%e6%8a%97adc%e8%8d%af%e7%89%a9jskn003%e6%be%b3%e5%a4%a7%e5%88%a9%e4%ba%9a%e2%85%b0%e6%9c%9f%e4%b8%b4%e5%ba%8a%e7%a0%94%e7%a9%b6%e6%95%b0%e6%8d%ae%e4%ba%ae%e7%9b%b82024-aacr%e5%b9%b4","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/20240410074100110455","title":{"rendered":"HER2\u53cc\u6297ADC\u836f\u7269JSKN003\u6fb3\u5927\u5229\u4e9a\u2160\u671f\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u4eae\u76f82024 AACR\u5e74\u4f1a"},"content":{"rendered":"<ul type=\"disc\">\n<li>\u672c\u6b21AACR\u4f1a\u8bae\u4e0a\u62a5\u9053\u7684\u662fJSKN003\u5728\u5242\u91cf\u9012\u589e\u671f\uff08\u2160a\uff09\u7684\u7814\u7a76\u7ed3\u679c\u3002<\/li>\n<li>JSKN003\u6cbb\u7597HER2\u8868\u8fbe\u665a\u671f\/\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\u663e\u793a\u51fa\u4ee4\u4eba\u9f13\u821e\u7684\u7597\u6548\u4fe1\u53f7\uff0cHER2\u9633\u6027\u4e73\u817a\u764c\u60a3\u8005ORR\u8fbe\u5230100%\u3002\u8010\u53d7\u6027\u548c\u5b89\u5168\u6027\u826f\u597d\uff0c\u672a\u53d1\u751fDLT\uff0cMTD\u5c1a\u672a\u8fbe\u5230\u3002<\/li>\n<\/ul>\n<p><p><span class=\"legendSpanClass\">\u4e2d\u56fd\u82cf\u5dde<\/span><span class=\"legendSpanClass\">2024\u5e744\u670810\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u5eb7\u5b81\u6770\u745e\u751f\u7269\u5236\u836f\uff08\u80a1\u7968\u4ee3\u7801\uff1a9966.HK\uff09\u5ba3\u5e03\uff0c\u516c\u53f8\u57282024\u5e74\u7f8e\u56fd\u764c\u75c7\u7814\u7a76\u534f\u4f1a\u5e74\u4f1a\u4e0a\uff08AACR 2024\uff09\uff0c\u4ee5\u58c1\u62a5\u5f62\u5f0f\u516c\u5e03\u4e86HER2\u53cc\u6297\u5076\u8054\u836f\u7269JSKN003\u5728\u6fb3\u5927\u5229\u4e9a\u6cbb\u7597HER2\u8868\u8fbe\u665a\u671f\u5b9e\u4f53\u7624\u7684\u2160\u671f\u4e34\u5e8a\u7814\u7a76\u6570\u636e\uff08\u7814\u7a76\u7f16\u53f7\uff1aJSKN003-101\uff09\u3002<\/p>\n<p><b>\u4e3b\u9898\uff1a<\/b>JSKN003\u7528\u4e8e\u6cbb\u7597\u665a\u671f\/\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\u7684\u5b89\u5168\u6027\u548c\u7597\u6548\uff1a\u4e00\u9879\u9996\u6b21\u5728\u4eba\u4f53\u4e2d\u8fdb\u884c\u7684\u3001\u5242\u91cf\u9012\u589e\u548c\u5242\u91cf\u6269\u5c55\u3001\u591a\u4e2d\u5fc3\u3001\u5f00\u653e\u7684I\u671f\u7814\u7a76<br \/><b>\u6458\u8981\u7f16\u53f7\uff1a<\/b>CT179<br \/><b>\u5c55\u793a\u5730\u70b9\uff1a<\/b>Poster Section 48<br \/><b>\u4e3b\u8981\u7814\u7a76\u8005\uff1a<\/b><span class=\"xn-person\">Claire Beecroft<\/span><br 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100%\uff085\/5\uff09\uff0cHER2\u4f4e\u8868\u8fbe\u4e73\u817a\u764c\u60a3\u8005ORR\u4e3a50%\uff085\/10\uff09\u3002<\/p>\n<p><b>\u5b89\u5168\u6027\uff1a<\/b>\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\uff08TRAEs\uff09\u53d1\u751f27\u4f8b\uff0884.4%\uff09\uff0c4\u4f8b\u60a3\u8005\uff0812.5%\uff09\u53d1\u751f3\u7ea7TRAE\uff0c1\u4f8b\u60a3\u8005\uff083.1%\uff09\u53d1\u751f2\u7ea7\u95f4\u8d28\u6027\u80ba\u708e\uff087.3mg\/kg\u7ec4\uff09\u3002\u53d1\u751f\u7387\u8d85\u8fc710%\u7684\u6240\u6709\u7ea7\u522b\u5e38\u89c1TRAE\u4e3a\uff1a\u8179\u6cfb\uff0862.5%\uff09\u3001\u6076\u5fc3\uff0853.1%\uff09\u3001\u75b2\u4e4f\uff0821.9%\uff09\u3001\u5455\u5410\uff0821.9%\uff09\u3001\u98df\u6b32\u51cf\u9000\uff0818.8%\uff09\u3001\u8179\u75db\uff0812.5%\uff09\u3001\u56f0\u5026\uff0812.5%\uff09\u548c\u8131\u53d1\uff0812.5%\uff09\u3002\u8840\u6db2\u5b66\u6bd2\u6027\u53d1\u751f\u7387\u6781\u4f4e\u3002\u65e0TRAE\u5bfc\u81f4\u7684\u6b7b\u4ea1\u6216\u7ec8\u6b62\u6cbb\u7597\u3002\u6240\u6709\u60a3\u8005\u5747\u5df2\u5b8c\u6210\u5242\u91cf\u9650\u5236\u6027\u6bd2\u6027\uff08DLT\uff09\u89c2\u5bdf\u671f\uff0c\u672a\u53d1\u751fDLT\u4e8b\u4ef6\uff0c\u7814\u7a76\u672a\u8fbe\u5230\u6700\u5927\u8010\u53d7\u5242\u91cf\uff08MTD\uff09\u3002<\/p>\n<p><b>PK: 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