\u9999\u6e2f\u3001\u9a6c\u91cc\u5170\u5dde\u5fb7\u56fd\u57ce\u548c\u4e2d\u56fd\u82cf\u5dde<\/span>2024\u5e743\u670812\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — Sirnaomics Ltd.<\/b>\uff08"\u516c\u53f8"\uff0c\u80a1\u4efd\u4ee3\u53f7\uff1a2257.HK\uff0c\u8fde\u540c\u5176\u9644\u5c5e\u516c\u53f8\uff0c\u7edf\u79f0"\u96c6\u56e2"\u6216"Sirnaomics"\uff09\uff0c\u4e00\u5bb6\u884c\u4e1a\u9886\u5148\u7684\u4e13\u6ce8\u4e8e\u63a2\u7d22\u53ca\u5f00\u53d1RNAi\u7597\u6cd5\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\u3002Sirnaomics\u4eca\u5929\u5ba3\u5e03\u53d7\u9080\u51fa\u5e2d2024 OPT\u5cf0\u4f1a\uff08\u5be1\u6838\u82f7\u9178\u4e0emRNA \u7597\u6cd5\u5cf0\u4f1a\uff09\u5e76\u5206\u4eab\u516c\u53f8\u57fa\u4e8eGalNAc-RNAi\u7597\u6cd5\u7684\u53cc\u9776\u5411\u521b\u65b0muRNA\u9012\u9001\u5e73\u53f0GalAhead™\u53ca\u5176\u76f8\u5173\u7ba1\u7ebf\u9879\u76ee\u7684\u6700\u65b0\u8fdb\u5c55\u30022024\u5e74OPT\u5cf0\u4f1a\u5c06\u4e8e2024\u5e743\u670813\u65e5-14\u65e5\u5728\u7f8e\u56fd\u6ce2\u58eb\u987f\u4e3e\u884c\u3002<\/p>\n \u57fa\u4e8eGalAhead™ mxRNA\u5355\u9776\u70b9\u53d6\u5f97\u7684\u8fdb\u5c55\uff0cSirnaomics\u7814\u53d1\u51fa\u4e00\u79cd\u57fa\u4e8eRNAi\u7597\u6cd5\u7684\u4e13\u6709\u9012\u9001\u5e73\u53f0GalAhead™ muRNA\uff0c\u53ef\u540c\u65f6\u6291\u5236\u591a\u4e2a\u57fa\u56e0\u3002GalAhead™ muRNA\u548cmxRNA\u4e00\u6837\u91c7\u7528\u4e86GalNac\u914d\u4f53\uff0c\u4e3a\u4e00\u79cd\u7ecf\u8fc7\u4e34\u5e8a\u9a8c\u8bc1\u7684RNAi\u89e6\u53d1\u5668\u9012\u9001\u81f3\u809d\u810f\u809d\u7ec6\u80de\u4ee5\u6cbb\u7597\u809d\u810f\u76f8\u5173\u75be\u75c5\u7684\u6982\u5ff5\u7597\u6cd5\u3002muRNA \u6982\u5ff5\u7597\u6cd5\u91c7\u7528\u72ec\u7279\u7684 RNAi \u8bbe\u8ba1\uff0c\u7531\u5305\u542b\u4e24\u6761\u53cd\u4e49\u94fe\u3001\u4e24\u6761\u4e92\u8865\u9002\u914d\u94fe\u7684\u53cc\u94fe\u7ec4\u6210\u53ca\u5176\u7279\u5b9a\u7684\u5de5\u7a0b\u5316\u53ef\u53d8\u70b9\u3002\u88c2\u89e3\u70b9\u53ef\u4f7f muRNA \u5728\u9001\u5165\u7ec6\u80de\u540e\u5728\u6eb6\u9176\u4f53\u5185\u9014\u5f84\u4e2d\u5206\u89e3\u6210\u4e24\u4e2a\u5355\u72ec\u7684 RNAi \u89e6\u53d1\u5668\uff0c\u800c\u4e2a\u4f53\u5316\u540e\u7684RNAi\u89e6\u53d1\u5668\u53ef\u5206\u522b\u9488\u5bf9\u5404\u81ea\u7684\u9776\u5411\u57fa\u56e0\u3002<\/p>\n \u4ece\u751f\u7269\u5b66\u7684\u89d2\u5ea6\u6765\u770b\uff0cmuRNA\u6982\u5ff5\u7597\u6cd5\u5728\u5bf9\u8fc7\u5ea6\u6fc0\u6d3b\u7684\u751f\u7269\u901a\u8def\u8fdb\u884c\u8c03\u8282\u65f6\uff0c\u4ea6\u53ef\u4ee4\u5176\u751f\u7406\u529f\u80fd\u5982\u5e38\u8fd0\u4f5c\u3002\u5728\u53e6\u4e00\u79cd\u60c5\u51b5\u4e0b\uff0cmuRNA \u53ef\u4ee5\u540c\u65f6\u9488\u5bf9\u4e24\u79cd\u6216\u4e24\u79cd\u4ee5\u4e0a\u975e\u76f8\u5173\u7684\u9002\u5e94\u75c7\uff0c\u800c\u8fd9\u4e9b\u9002\u5e94\u75c7\u7684\u60a3\u8005\u7fa4\u4f53\u5f80\u5f80\u591a\u75c5\u5171\u5b58\u3002GalAhead™ muRNA\u7597\u6cd5 \u4e3a RNAi \u9886\u57df\u63d0\u4f9b\u4e86\u4e00\u4e2a\u5168\u65b0\u7684\u3001\u9f13\u821e\u4eba\u5fc3\u7684\u65b9\u5411\uff0c\u6709\u671b\u4e3a\u533b\u7597\u9700\u6c42\u672a\u83b7\u6ee1\u8db3\u7684\u60a3\u8005\u7fa4\u4f53\u63d0\u4f9b\u5b89\u5168\u548c\u957f\u6548\u7684\u6cbb\u7597\u65b9\u6cd5\u3002<\/p>\n 2024\u5e74OPT\u5cf0\u4f1a\uff08Oligonucleotide & mRNA Therapeutics Congress\uff09\u6f14\u8bb2\u8be6\u60c5<\/p>\n Weterings\u535a\u58eb\u5c06\u4f5c\u4e3a\u5cf0\u4f1a\u4e3b\u5e2d\u51fa\u5e2d\u5e76\u4e3b\u6301\u540c\u65e5\u4e0b\u53483:40\u4e3e\u884c\u7684\u5cf0\u4f1a\u4e3b\u9898\u8bba\u575b\uff0c\u5e76\u5c31RNA\u7597\u6cd5\u7684\u529f\u6548\u4e0e\u672a\u6765\u5e94\u7528\u4f5c\u5f00\u9898\u6f14\u8bb2\u3002<\/p>\n \u5173\u4e8e<\/u><\/b>Sirnaomics Ltd. (<\/u><\/b>\u80a1\u4efd\u4ee3\u53f7<\/u><\/b>: 2257) \u9999\u6e2f\u3001\u9a6c\u91cc\u5170\u5dde\u5fb7\u56fd\u57ce\u548c\u4e2d\u56fd\u82cf\u5dde2024\u5e743\u670812\u65e5 \/\u7f8e\u901a\u793e\/ — Sirnaomics Ltd.\uff08"\u516c\u53f8"\uff0c\u80a1\u4efd\u4ee3\u53f7\uff1a2257.HK\uff0c\u8fde\u540c\u5176\u9644\u5c5e\u516c\u53f8\uff0c\u7edf\u79f0"\u96c6\u56e2"\u6216"Sirnaomics"\uff09\uff0c\u4e00\u5bb6\u884c\u4e1a\u9886\u5148\u7684\u4e13\u6ce8\u4e8e\u63a2\u7d22\u53ca\u5f00\u53d1RNAi\u7597\u6cd5\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\u3002Sirnaomics\u4eca\u5929\u5ba3\u5e03\u53d7\u9080\u51fa\u5e2d2024 OPT\u5cf0\u4f1a\uff08\u5be1\u6838\u82f7\u9178\u4e0emRNA \u7597\u6cd5\u5cf0\u4f1a\uff09\u5e76\u5206\u4eab\u516c\u53f8\u57fa\u4e8eGalNAc-RNAi\u7597\u6cd5\u7684\u53cc\u9776\u5411\u521b\u65b0muRNA\u9012\u9001\u5e73\u53f0GalAhead™\u53ca\u5176\u76f8\u5173\u7ba1\u7ebf\u9879\u76ee\u7684\u6700\u65b0\u8fdb\u5c55\u30022024\u5e74OPT\u5cf0\u4f1a\u5c06\u4e8e2024\u5e743\u670813\u65e5-14\u65e5\u5728\u7f8e\u56fd\u6ce2\u58eb\u987f\u4e3e\u884c\u3002 \u57fa\u4e8eGalAhead™ mxRNA\u5355\u9776\u70b9\u53d6\u5f97\u7684\u8fdb\u5c55\uff0cSirnaomics\u7814\u53d1\u51fa\u4e00\u79cd\u57fa\u4e8eRNAi\u7597\u6cd5\u7684\u4e13\u6709\u9012\u9001\u5e73\u53f0GalAhead™ muRNA\uff0c\u53ef\u540c\u65f6\u6291\u5236\u591a\u4e2a\u57fa\u56e0\u3002GalAhead™ muRNA\u548cmxRNA\u4e00\u6837\u91c7\u7528\u4e86GalNac\u914d\u4f53\uff0c\u4e3a\u4e00\u79cd\u7ecf\u8fc7\u4e34\u5e8a\u9a8c\u8bc1\u7684RNAi\u89e6\u53d1\u5668\u9012\u9001\u81f3\u809d\u810f\u809d\u7ec6\u80de\u4ee5\u6cbb\u7597\u809d\u810f\u76f8\u5173\u75be\u75c5\u7684\u6982\u5ff5\u7597\u6cd5\u3002muRNA \u6982\u5ff5\u7597\u6cd5\u91c7\u7528\u72ec\u7279\u7684 RNAi \u8bbe\u8ba1\uff0c\u7531\u5305\u542b\u4e24\u6761\u53cd\u4e49\u94fe\u3001\u4e24\u6761\u4e92\u8865\u9002\u914d\u94fe\u7684\u53cc\u94fe\u7ec4\u6210\u53ca\u5176\u7279\u5b9a\u7684\u5de5\u7a0b\u5316\u53ef\u53d8\u70b9\u3002\u88c2\u89e3\u70b9\u53ef\u4f7f muRNA \u5728\u9001\u5165\u7ec6\u80de\u540e\u5728\u6eb6\u9176\u4f53\u5185\u9014\u5f84\u4e2d\u5206\u89e3\u6210\u4e24\u4e2a\u5355\u72ec\u7684 RNAi \u89e6\u53d1\u5668\uff0c\u800c\u4e2a\u4f53\u5316\u540e\u7684RNAi\u89e6\u53d1\u5668\u53ef\u5206\u522b\u9488\u5bf9\u5404\u81ea\u7684\u9776\u5411\u57fa\u56e0\u3002 \u4ece\u751f\u7269\u5b66\u7684\u89d2\u5ea6\u6765\u770b\uff0cmuRNA\u6982\u5ff5\u7597\u6cd5\u5728\u5bf9\u8fc7\u5ea6\u6fc0\u6d3b\u7684\u751f\u7269\u901a\u8def\u8fdb\u884c\u8c03\u8282\u65f6\uff0c\u4ea6\u53ef\u4ee4\u5176\u751f\u7406\u529f\u80fd\u5982\u5e38\u8fd0\u4f5c\u3002\u5728\u53e6\u4e00\u79cd\u60c5\u51b5\u4e0b\uff0cmuRNA \u53ef\u4ee5\u540c\u65f6\u9488\u5bf9\u4e24\u79cd\u6216\u4e24\u79cd\u4ee5\u4e0a\u975e\u76f8\u5173\u7684\u9002\u5e94\u75c7\uff0c\u800c\u8fd9\u4e9b\u9002\u5e94\u75c7\u7684\u60a3\u8005\u7fa4\u4f53\u5f80\u5f80\u591a\u75c5\u5171\u5b58\u3002GalAhead™ muRNA\u7597\u6cd5 \u4e3a RNAi \u9886\u57df\u63d0\u4f9b\u4e86\u4e00\u4e2a\u5168\u65b0\u7684\u3001\u9f13\u821e\u4eba\u5fc3\u7684\u65b9\u5411\uff0c\u6709\u671b\u4e3a\u533b\u7597\u9700\u6c42\u672a\u83b7\u6ee1\u8db3\u7684\u60a3\u8005\u7fa4\u4f53\u63d0\u4f9b\u5b89\u5168\u548c\u957f\u6548\u7684\u6cbb\u7597\u65b9\u6cd5\u3002 2024\u5e74OPT\u5cf0\u4f1a\uff08Oligonucleotide & mRNA Therapeutics Congress\uff09\u6f14\u8bb2\u8be6\u60c5 \u6f14\u8bb2\u4e3b\u9898\uff1aGalAhead™\uff1a\u4e00\u79cd\u53ef\u4e0b\u8c03\u5355\u7c7b\u57fa\u56e0\u6216\u591a\u7c7b\u57fa\u56e0\u7684\u65b0\u578b\u6cbb\u7597\u6027GalNAc-RNAi\u9012\u9001\u5e73\u53f0 \u6f14\u8bb2\u8005\uff1aSirnaomics RNA\u7597\u6cd5\u4e0e\u9012\u9001\u7814\u53d1\u526f\u603b\u88c1Jim Weterings\u535a\u58eb \u6f14\u8bb2\u5185\u5bb9\uff1a \u4ecb\u7ecdGalAhead™\u2014\u2014Sirnaomics\u65b0\u578bGalNAc-RNAi\u9012\u9001\u5e73\u53f0 GalAhead™ muRNA\u6280\u672f\u5728\u4f53\u5185\u53ca\u4f53\u5916\u7684\u9a8c\u8bc1 muRNA\u53cc\u9776\u70b9\u8bbe\u8ba1\u76f8\u5173\u9879\u76ee\u8fdb\u5c55 Weterings\u535a\u58eb\u5c06\u4f5c\u4e3a\u5cf0\u4f1a\u4e3b\u5e2d\u51fa\u5e2d\u5e76\u4e3b\u6301\u540c\u65e5\u4e0b\u53483:40\u4e3e\u884c\u7684\u5cf0\u4f1a\u4e3b\u9898\u8bba\u575b\uff0c\u5e76\u5c31RNA\u7597\u6cd5\u7684\u529f\u6548\u4e0e\u672a\u6765\u5e94\u7528\u4f5c\u5f00\u9898\u6f14\u8bb2\u3002 \u5173\u4e8eSirnaomics Ltd. 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