{"id":106232,"date":"2024-02-27T17:09:00","date_gmt":"2024-02-27T10:09:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/20240227170900106232"},"modified":"2024-02-28T00:26:37","modified_gmt":"2024-02-27T16:26:37","slug":"takeda%e5%ae%a3%e5%b8%83%e4%b8%8ebiological-e-%e5%bc%80%e5%b1%95%e5%8d%b0%e5%ba%a6%e5%88%b6%e9%80%a0%e7%96%ab%e8%8b%97%e7%94%9f%e4%ba%a7%e5%90%88%e4%bd%9c","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/20240227170900106232","title":{"rendered":"Takeda\u5ba3\u5e03\u4e0eBiological E. \u5f00\u5c55\u201c\u5370\u5ea6\u5236\u9020\u201d\u75ab\u82d7\u751f\u4ea7\u5408\u4f5c"},"content":{"rendered":"<p class=\"prntaj\"><b><span id=\"spanHghlt1029\" class=\"legendSpanClass\">\u52a0\u901f\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\u4f9b\u5e94<\/span><\/b><\/p>\n<p class=\"prntaj\"><b><i>&#8211; \u65b0\u7684\u6218\u7565\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\u5c06\u63d0\u5347\u75ab\u82d7\u751f\u4ea7\u80fd\u529b\uff0c\u4ee5\u652f\u6301\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\u7684\u5168\u7403\u4f9b\u5e94\uff0c\u6269\u5927\u6b66\u7530\u5236\u836f<\/i><\/b><b><i> (Takeda)<\/i><\/b><b><i>\u5728\u75ab\u82d7\u751f\u4ea7\u9886\u57df\u7684\u8db3\u8ff9\u3002<\/i><\/b><\/p>\n<p class=\"prntaj\"><b><i>&#8211; \u5230 <\/i><\/b><b><i>2030 <\/i><\/b><b><i>\u5e74\uff0c\u8be5\u6218\u7565\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\u5c06\u6bcf\u5e74\u4f9b\u5e94\u591a\u8fbe<\/i><\/b><b><i> 5000 <\/i><\/b><b><i>\u4e07\u5242\u75ab\u82d7\uff0c\u4ee5\u6ee1\u8db3\u5168\u7403\u516c\u5171\u536b\u751f\u9700\u6c42\u3002<\/i><\/b><\/p>\n<p class=\"prntaj\"><b><i>&#8211; \u9aa8\u75db\u70ed\u75c7\u662f\u5168\u7403\u6027\u7684\u516c\u5171\u536b\u751f\u5a01\u80c1\uff0c\u4e3a\u5e2e\u52a9\u51cf\u8f7b\u75be\u75c5\u8d1f\u62c5\uff0c\u6b66\u7530\u5236\u836f <\/i><\/b><b><i>(Takeda)<\/i><\/b><b><i>\u5c06<\/i><\/b><b><i>\u4e0d\u65ad\u52aa\u529b\u6269\u5927\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\u7684\u4f9b\u5e94\u80fd\u529b\u3002<\/i><\/b><\/p>\n<p id=\"temp_ReleaseStart\"><span class=\"legendSpanClass\">\u65b0\u52a0\u5761<\/span><span class=\"legendSpanClass\">2024\u5e742\u670827\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; <a href=\"http:\/\/www.takeda.com\/\" target=\"_blank\" rel=\"nofollow noopener\">Takeda<\/a>\u6b66\u7530\u5236\u836f\uff08<b>TSE:4502\/NYSE:TAK<\/b><b>\uff09<\/b>\u4eca\u65e5\u5ba3\u5e03\u4e0e\u5370\u5ea6\u9886\u5148\u7684\u75ab\u82d7\u548c\u751f\u7269\u5236\u54c1\u516c\u53f8 Biological E. Limited \u5efa\u7acb\u6218\u7565\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\uff0c\u5171\u540c\u751f\u4ea7\u6b66\u7530\u65d7\u4e0b\u7684\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7 TAK-003\u3002\u9aa8\u75db\u70ed\u75c7\u8fd1\u5e74\u88ab\u5e7f\u6cdb\u8ba4\u4e3a\u662f\u5168\u7403\u516c\u5171\u536b\u751f\u5a01\u80c1\u4e4b\u4e00\uff0c\u800c\u6b64\u6b21\u5408\u4f5c\u4e0d\u4ec5\u6807\u5fd7\u7740\u5168\u7403\u6297\u51fb\u9aa8\u75db\u70ed\u75c7\u7684\u5173\u952e\u6b65\u9aa4\uff0c\u540c\u65f6\u4e5f\u4e0e\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\uff08WHO\uff09\u6240\u5236\u5b9a\u7684 \u201c\u4e8e2030\u5e74\u5b9e\u73b0\u9aa8\u75db\u70ed\u75c7\u96f6\u81f4\u6b7b\u7387<sup>[i]<\/sup>.\u201d \u7684\u7279\u5b9a\u75be\u75c5\u76ee\u6807\u4e00\u81f4\u3002<\/p>\n<p class=\"prntaj\">\u6b66\u7530\u4e0eBiological E.\u7684\u5408\u4f5c\u5c06\u5927\u5927\u63d0\u9ad8\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\u7684\u751f\u4ea7\u80fd\u529b\uff0c\u786e\u4fdd\u75ab\u82d7\u5728\u5168\u7403\u7684\u53ef\u6301\u7eed\u4f9b\u5e94\u3002Biological E. \u5c06\u6269\u5927\u4ea7\u80fd\uff0c\u5176\u5e74\u4ea7\u91cf\u5c06\u53ef\u8fbe\u5230\u6bcf\u5e74 5000 \u4e07\u5242\uff0c\u4ece\u800c\u52a0\u5feb\u6b66\u7530\u5236\u836f\u5728\u4e3a\u6765\u5341\u5e74\u5185\u5b9e\u73b0\u5e74\u4ea7 1 \u4ebf\u5242\u7684\u76ee\u6807\u3002<\/p>\n<p class=\"prntaj\"><b>\u7279\u4f26\u7518\u7eb3\u90a6<\/b><b> (Telangana) <\/b><b>\u9996\u5e2d\u90e8\u957f<\/b>&nbsp;<b>Sri Anumula Revanth Reddy<\/b>\uff0c\u5728\u7279\u4f26\u7518\u7eb3\u90a6\u653f\u5e9c\u7ec4\u7ec7\u7684\u5730\u533a\u751f\u547d\u79d1\u5b66\u4e0e\u533b\u7597\u4fdd\u5065\u8bba\u575b BioAsia 2024 \u4e0a\u5ba3\u5e03\u4e86\u53cc\u65b9\u7684\u5408\u4f5c\u5173\u7cfb\u3002\u4ed6\u5728\u53d1\u8a00\u4e2d\u6307\u51fa\uff1a&quot;\u6211\u4eec\u5f88\u9ad8\u5174\u6b66\u7530\u5236\u836f\u548cBiological E.\u5408\u4f5c\u751f\u4ea7\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\u7684\u8bbe\u65bd\u5c06\u843d\u6237\u7279\u4f26\u7518\u7eb3\u90a6\uff08Telangana\uff09\u7684\u6d77\u5fb7\u62c9\u5df4\uff08Hyderabad\uff09\u3002\u7279\u4f26\u7518\u7eb3\u90a6\u4e3a\u751f\u547d\u79d1\u5b66\uff0c\u7279\u522b\u662f\u75ab\u82d7\u548c\u751f\u7269\u5236\u5242\u7684\u7814\u53d1\u548c\u5236\u9020\u63d0\u4f9b\u4e86\u826f\u597d\u7684\u73af\u5883\u3002\u6211\u5f88\u9ad8\u5174\u8fd9\u4e2a\u5de5\u5382\u80fd\u52a0\u901f\u75ab\u82d7\u5728\u5370\u5ea6\u53ca\u5176\u4ed6\u9aa8\u75db\u70ed\u75c7\u6d41\u884c\u56fd\u5bb6\u53ca\u5730\u533a\u7684\u4f9b\u5e94\u3002&quot;<\/p>\n<p class=\"prntaj\"><b>\u7279<\/b><b>\u4f26<\/b><b>\u7518\u7eb3\u90a6\u5de5\u4e1a\u548c\u5546\u4e1a\u90e8\u957f <\/b><b><span class=\"xn-person\">Sri Duddilla Sridhar Babu<\/span><\/b> \u6307\u51fa\uff1a&quot;\u900f\u8fc7\u6b66\u7530\u5236\u836f\u7684\u6280\u672f\u4e13\u957f\u548cBiological E.\u7684\u5236\u9020\u80fd\u529b\uff0c\u5c06\u6709\u52a9\u4e8e\u63d0\u9ad8\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\u7684\u53ef\u53ca\u6027\u548c\u53ef\u8d1f\u62c5\u6027\uff0c\u4e3a\u5370\u5ea6\u7684\u533b\u7597\u4fdd\u5065\u7684\u97e7\u529b\u548c\u672a\u6765\u51c6\u5907\u505a\u51fa\u8d21\u732e\u3002\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u652f\u6301\u8fd9\u6b21\u7ed3\u5408\u79d1\u5b66\u3001\u653f\u5e9c\u548c\u4ea7\u4e1a\u7684\u5408\u4f5c\uff0c\u63a8\u52a8\u548c\u6269\u5927\u521b\u65b0\uff0c\u5b9e\u73b0\u5168\u6c11\u5065\u5eb7\u8986\u76d6\u3002&quot;<\/p>\n<p class=\"prntaj\"><b>\u6b66\u7530\u5236\u836f\u5168\u7403\u75ab\u82d7\u4e8b\u4e1a\u90e8\u603b\u88c1\u3001\u533b\u5b66\u535a\u58eb<\/b><b><span class=\"xn-person\">Gary Dubin<\/span><\/b>\u8868\u793a\uff1a\u201c\u6b66\u7530\u9aa8\u75db\u70ed\u75c7\u9879\u76ee\u7684\u957f\u671f\u76ee\u6807\u662f\u4e3a\u90a3\u4e9b\u53ef\u80fd\u53d7\u76ca\u4e8e\u514d\u75ab\u63a5\u79cd\u7684\u9ad8\u5371\u4eba\u7fa4\u63d0\u4f9bTAK-003\u75ab\u82d7\u3002\u5728\u8fc7\u53bb\u4e00\u5e74\u91cc\uff0c\u6211\u4eec\u4e0d\u4ec5\u6210\u529f\u5728\u79c1\u8425\u5e02\u573a\u63a8\u51faTAK-003\uff0c\u6700\u8fd1\u66f4\u5728\u4e00\u90e8\u5206\u516c\u5171\u9879\u76ee\u4e2d\u63a8\u51faTAK-003\uff0c\u540c\u65f6\u4e0e\u5404\u754c\u5408\u4f5c\u4f19\u4f34\u4e00\u8d77\u4e3a\u52a0\u5f3a\u5bf9\u516c\u5171\u536b\u751f\u5065\u5eb7\u7684\u7ef4\u62a4\u3002\u4eca\u65e5\uff0c\u6211\u4eec\u5f88\u81ea\u8c6a\u5730\u5ba3\u5e03\u4e0e Biological E. Limited \u6b63\u5f0f\u6210\u4e3a\u6218\u7565\u751f\u4ea7\u5408\u4f5c\u4f19\u4f34\u3002\u8be5\u516c\u53f8\u5728\u75ab\u82d7\u751f\u4ea7\u65b9\u9762\u62e5\u6709\u6df1\u539a\u7684\u4e13\u4e1a\u77e5\u8bc6\uff0c\u5e76\u957f\u671f\u652f\u6301\u4e16\u754c\u5404\u5730\u7684\u516c\u5171\u536b\u751f\u9879\u76ee\u3002\u901a\u8fc7\u5927\u5e45\u63d0\u9ad8 TAK-003 \u591a\u5242\u91cf\u74f6\u7684\u751f\u4ea7\u80fd\u529b\uff0c\u4e0d\u4ec5\u80fd\u652f\u6301\u5168\u7403\u9aa8\u75db\u70ed\u75c7\u9632\u6cbb\u5de5\u4f5c\uff0c\u540c\u65f6\u4e5f\u80fd\u4e3a\u66f4\u591a\u9aa8\u75db\u70ed\u75c7\u6d41\u884c\u56fd\u5bb6\u63d0\u4f9b\u957f\u671f\u7684\u75ab\u82d7\u4f9b\u5e94\u3002\u201d<\/p>\n<p class=\"prntaj\">\u4f5c\u4e3a\u4f20\u64ad\u901f\u5ea6\u6700\u5feb\u7684\u868a\u5a92\u75c5\u6bd2\u6027\u75be\u75c5\uff0c\u76ee\u524d\u5168\u7403\u7ea6\u6709\u4e00\u534a\u4eba\u53e3\u6b63\u9762\u4e34\u60a3\u4e0a\u9aa8\u75db\u70ed\u75c7\u7684\u98ce\u9669<sup>[ii]<\/sup>\u3002\u5728\u5370\u5ea6\u548c\u4e1c\u5357\u4e9a\u5730\u533a\uff0c\u6709 13 \u4ebf\u4eba\u751f\u6d3b\u5728\u9aa8\u75db\u70ed\u75c7\u6d41\u884c\u5730\u533a\uff0c\u800c\u5176\u4e2d\u6cf0\u56fd\u3001\u5370\u5ea6\u548c\u5370\u5ea6\u5c3c\u897f\u4e9a\u5219\u662f\u9aa8\u75db\u70ed\u75c7\u75ab\u60c5\u6700\u4e25\u91cd\u7684\u56fd\u5bb6<sup>[iii]<\/sup>\u3002\u6700\u8fd1\uff0c<a href=\"https:\/\/www.who.int\/news\/item\/02-10-2023-who-recommends-r21-matrix-m-vaccine-for-malaria-prevention-in-updated-advice-on-immunization\" target=\"_blank\" rel=\"nofollow noopener\">\u4e16\u536b\u7ec4\u7ec7\u514d\u75ab\u6218\u7565\u54a8\u8be2\u4e13\u5bb6<\/a>\uff08Strategic Advisory Group of Experts\uff0c\u7b80\u79f0SAGE\uff09\u5efa\u8bae\uff0c\u5728\u9aa8\u75db\u70ed\u75c7\u9ad8\u8d1f\u62c5\u548c\u4f20\u64ad\u5ea6\u8f83\u9ad8\u7684\u5730\u533a\u4f7f\u7528\u6b66\u7530\u5236\u836f\u7684\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\uff0c\u4ee5\u52a0\u5f3a\u5bf9\u516c\u5171\u536b\u751f\u5065\u5eb7\u7684\u7ef4\u62a4\u3002<\/p>\n<p class=\"prntaj\"><b>\u6b66\u7530\u5236\u836f\u5370\u5ea6\u548c\u4e1c\u5357\u4e9a\u591a\u56fd\u7ec4\u7ec7\u8d1f\u8d23\u4eba<\/b><b><span class=\"xn-person\">Dion Warren<\/span><\/b><b>\u8868\u793a\uff1a<\/b>\u201c\u8fd9\u4e00\u6218\u7565\u5408\u4f5c\u518d\u6b21\u5370\u8bc1\u4e86\u6b66\u7530\u4e3a\u5168\u7403\u6c11\u4f17\u63d0\u4f9b\u6709\u6548\u4fdd\u62a4\u5065\u5eb7\u75ab\u82d7\u7684\u51b3\u5fc3\uff0c\u4e5f\u4f53\u73b0\u4e86\u516c\u53f8\u4e3a\u5728\u4e9a\u6d32\u52a0\u5f3a\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\u6240\u4f5c\u7684\u52aa\u529b\u3002\u968f\u7740\u75ab\u82d7\u5728\u6cf0\u56fd\u3001\u5370\u5ea6\u5c3c\u897f\u4e9a\u4ee5\u53ca\u6700\u8fd1\u5728\u9a6c\u6765\u897f\u4e9a\u83b7\u5f97\u6279\u51c6\uff0c\u6211\u4eec\u5bf9\u672a\u6765\u5145\u6ee1\u4fe1\u5fc3\u3002\u6211\u4eec\u76f8\u4fe1\u9aa8\u75db\u70ed\u75c7\u7efc\u5408\u9632\u63a7\u673a\u5236\u5c06\u53ef\u6709\u6548\u6539\u5584\u5370\u5ea6\u3001\u4e1c\u5357\u4e9a\u4ee5\u53ca\u5176\u4ed6\u5730\u533a\u65e0\u6570\u4eba\u6c11\u7684\u751f\u6d3b\u3002\u201d<\/p>\n<p class=\"prntaj\">\u6700\u8fd1\uff0c\u300a\u67f3\u53f6\u5200\u5168\u7403\u5065\u5eb7\u300b\u6742\u5fd7\uff08<i>Th<\/i><i>e <\/i><i>Lancet Global Health<\/i><i>\uff09<\/i><a href=\"https:\/\/www.thelancet.com\/journals\/langlo\/article\/PIIS2214-109X(23)00522-3\/fulltext\" target=\"_blank\" rel=\"nofollow noopener\">\u53d1\u8868\u4e86\u6b66\u7530\u5236\u836f\u5173\u952e\u7684<\/a>\u9aa8\u75db\u70ed\u75c7\u56db\u4ef7\u514d\u75ab\u63a5\u79cd\u4e09\u671f\u7597\u6548\u7814\u7a76\uff08Phase 3 Tetravalent Immunization against Dengue Efficacy Study \uff0c\u7b80\u79f0TIDES\uff09\u7684<a href=\"https:\/\/www.thelancet.com\/journals\/langlo\/article\/PIIS2214-109X(23)00522-3\/fulltext\" target=\"_blank\" rel=\"nofollow noopener\">\u957f\u671f\u63a2\u7d22\u6027\u7ed3\u679c<\/a>\uff0c\u8868\u660eTAK-003\u75ab\u82d7\u5728\u63a5\u79cd\u540e\u7684\u56db\u5e74\u534a\uff0854\u4e2a\u6708\uff09\u5185\u4ecd\u5177\u6709\u9884\u9632\u9aa8\u75db\u70ed\u75c7\u7684\u4fdd\u62a4\u4f5c\u7528\u3002\u76ee\u524d\uff0c\u8be5\u75ab\u82d7\u5df2\u5728 30 \u591a\u4e2a\u56fd\u5bb6\u83b7\u5f97\u6279\u51c6\uff0c\u5305\u62ec\u6b27\u76df<sup>[iv]<\/sup>\u3001\u82f1\u56fd<sup>[v]<\/sup>\u3001\u5df4\u897f<sup>[vi]<\/sup>\u3001\u963f\u6839\u5ef7<sup>[vii]<\/sup>\u3001\u5370\u5ea6\u5c3c\u897f\u4e9a<sup>[viii]<\/sup>\u3001\u6cf0\u56fd<sup>[ix]<\/sup>\u548c\u9a6c\u6765\u897f\u4e9a<sup>[x]<\/sup>\uff0c\u7528\u4e8e\u9884\u9632\u4efb\u4f55\u8840\u6e05\u578b\u7684\u9aa8\u75db\u70ed\u75c7\u3002\u4eca\u540e\uff0c\u6b66\u7530\u5236\u836f\u5c06\u7ee7\u7eed\u76d1\u6d4b\u957f\u671f\u6570\u636e\uff0c\u5e76\u7ee7\u7eed\u5728\u66f4\u591a\u56fd\u5bb6\u8fdb\u884c\u76d1\u7ba1\u7533\u8bf7\uff0c\u6ee1\u8db3\u76f8\u5173\u516c\u5171\u536b\u751f\u9700\u6c42\uff0c\u8ba9\u9632\u8303\u80dc\u4e8e\u6cbb\u7597\u3002<\/p>\n<p class=\"prntaj\"><b><i>\u81f4\u7f16\u8f91<\/i><\/b><\/p>\n<p class=\"prntaj\"><i>\u8fd9\u4e9b\u7a81\u7834\u6027\u7814\u53d1\u6807\u5fd7\u7740\u6211\u4eec\u5728\u5168\u7403\u8303\u56f4\u5185\u52aa\u529b\u6297\u51fb<\/i><i>\u9aa8\u75db\u70ed\u75c7<\/i><i>\u6240\u53d6\u5f97\u7684\u91cd\u5927\u8fdb\u5c55\u3002\u6b66\u7530\u5236\u836f\u4ecd\u81f4\u529b\u4e8e\u5f00\u53d1\u4e00\u79cd\u53ef\u5e94\u5bf9\u7531\u4efb\u4f55\u75c5\u6bd2\u8840\u6e05\u578b\u5f15\u8d77\u7684\u6709\u75c7\u72b6<\/i><i>\u9aa8\u75db\u70ed\u75c7\u3001<\/i><i>\u4e14\u5b89\u5168\u7684<\/i><i>\u9aa8\u75db\u70ed\u75c7<\/i><i>\u75ab\u82d7\uff0c\u65e0\u8bba\u662f\u5426\u66fe\u611f\u67d3<\/i><i>\u9aa8\u75db\u70ed\u75c7<\/i><i>\uff0c\u90fd\u80fd\u4e3a\u9ad8\u5371\u4eba\u7fa4\u63d0\u4f9b\u4fdd\u62a4\u3002\u6b66\u7530\u5236\u836f\u5c06\u7ee7\u7eed\u4e0e\u533b\u7597\u5408\u4f5c\u4f19\u4f34\u3001\u653f\u5e9c\u548c\u793e\u533a\u5bc6\u5207\u5408\u4f5c\uff0c\u786e\u4fdd\u6309\u7167\u5f53\u5730\u6cd5\u89c4\u6210\u529f\u9884\u9632<\/i><i>\u9aa8\u75db\u70ed\u75c7<\/i><i>\u3002<\/i><\/p>\n<p class=\"prntaj\"><b>About Takeda <\/b><\/p>\n<p class=\"prntaj\">Takeda is focused on creating better health for people and a brighter future for the world. We aim to discover and deliver life-transforming treatments in our core therapeutic and business areas, including gastrointestinal and inflammation, rare diseases, plasma-derived therapies, oncology, neuroscience and vaccines. Together with our partners, we aim to improve the patient experience and advance a new frontier of treatment options through our dynamic and diverse pipeline. As a leading values-based, R&amp;D-driven biopharmaceutical company headquartered in <span class=\"xn-location\">Japan<\/span>, we are guided by our commitment to patients, our people and the planet. Our employees in approximately 80 countries and regions are driven by our purpose and are grounded in the values that have defined us for more than two centuries. For more information, visit <a href=\"http:\/\/www.takeda.com\/\" target=\"_blank\" rel=\"nofollow noopener\">www.takeda.com<\/a>.<\/p>\n<p class=\"prntaj\"><b>About TAK-<span id=\"spanHghlt3b9f\">003<\/span><\/b><b>&nbsp;(Dengue Tetravalent Vaccine [Live, Attenuated]) <\/b><\/p>\n<p class=\"prntaj\">TAK-003 is a dengue vaccine that is based on a live-attenuated dengue serotype 2 virus, which provides the genetic \u201cbackbone\u201d for all four dengue virus serotypes and is designed to protect against any of these serotypes.<sup>[xi]<\/sup><\/p>\n<p class=\"prntaj\">TAK-003 is currently approved in more than 30 countries including the European Union, the <span class=\"xn-location\">United Kingdom<\/span>, <span class=\"xn-location\">Brazil<\/span>, <span class=\"xn-location\">Argentina<\/span>, <span class=\"xn-location\">Indonesia<\/span>, <span class=\"xn-location\">Thailand<\/span> and <span class=\"xn-location\">Malaysia<\/span> for the prevention of dengue disease. The vaccine should be administered subcutaneously as a 0.5 mL dose at a two-dose (0 and 3 months) schedule according to the approved dosing regimen and in accordance with local recommendations and age guidelines.<sup>[xii]<\/sup>&nbsp;<\/p>\n<p><p>Approval code: C-ANPROM\/MY\/DENV\/0266<\/p>\n<p class=\"prntaj\"><b>Important Notice<\/b><\/p>\n<p class=\"prntaj\">For the purposes of this notice, \u201cpress release\u201d means this document, any oral presentation, any question and answer session and any written or oral material discussed or distributed by Takeda Pharmaceutical Company Limited (\u201cTakeda\u201d) regarding this release. This press release (including any oral briefing and any question-and-answer in connection with it) is not intended to, and does not constitute, represent or form part of any offer, invitation or solicitation of any offer to purchase, otherwise acquire, subscribe for, exchange, sell or otherwise dispose of, any securities or the solicitation of any vote or approval in any jurisdiction. No shares or other securities are being offered to the public by means of this press release. No offering of securities shall be made in <span class=\"xn-location\">the United States<\/span> except pursuant to registration under the U.S. Securities Act of 1933, as amended, or an exemption therefrom. This press release is being given (together with any further information which may be provided to the recipient) on the condition that it is for use by the recipient for information purposes only (and not for the evaluation of any investment, acquisition, disposal or any other transaction). Any failure to comply with these restrictions may constitute a violation of applicable securities laws.<\/p>\n<p class=\"prntaj\">The companies in which Takeda directly and indirectly owns investments are separate entities. In this press release, \u201cTakeda\u201d is sometimes used for convenience where references are made to Takeda and its subsidiaries in general. Likewise, the words \u201cwe\u201d, \u201cus\u201d and \u201cour\u201d are also used to refer to subsidiaries in general or to those who work for them. These expressions are also used where no useful purpose is served by identifying the <span id=\"spanHghltc36f\">particular company<\/span> or companies.<\/p>\n<div>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"1\" class=\"prnbcc\">\n<tbody>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[i]<\/sup> World Health Organization, Ending the neglect to attain the Sustainable Development Goals: A road map for neglected tropical diseases 2021\u20132030. Available at:&nbsp;<a href=\"https:\/\/www.who.int\/publications\/i\/item\/9789240010352\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow noopener\">https:\/\/www.who.int\/publications\/i\/item\/9789240010352<\/a>. Accessed: February 2024.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[ii]<\/sup> World Health Organization, Dengue and Severe Dengue. Available at: <a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/dengue-and-severe-dengue#:~:text=About%20half%20of%20the%20world&#039;s,urban%20and%20semi%2Durban%20areas\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow noopener\">https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/dengue-and-severe-dengue#:~:text=About%20half%20of%20the%20world&#8217;s,urban%20and%20semi%2Durban%20areas<\/a>. Accessed: February 2024.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[iii]<\/sup> World Health Organization, Dengue in South-East Asia. Available at: <a href=\"https:\/\/www.who.int\/southeastasia\/health-topics\/dengue-and-severe-dengue\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow noopener\">https:\/\/www.who.int\/southeastasia\/health-topics\/dengue-and-severe-dengue<\/a>. Accessed: February 2024.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[iv]<\/sup> European Medicines Agency, Qdenga. Available at: <a href=\"https:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/qdenga\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow noopener\">https:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/qdenga<\/a>. Accessed: February 2024.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[v]<\/sup> Medicines and Healthcare products Regulatory Agency, Marketing authorisations granted 15 January to 31 January 2023. Available at: <a href=\"https:\/\/assets.publishing.service.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/1134336\/Marketing_authorisations_granted_15_January_to_31_January_2023.pdf\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow noopener\">https:\/\/assets.publishing.service.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/1134336\/Marketing_authorisations_granted_15_January_to_31_January_2023.pdf<\/a>. Accessed February 2024.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[vi] <\/sup>Brazil\u2019s ANVISA approves Takeda\u2019s dengue vaccine Qdenga, Pharmceutical Technology, March 14, 2023. Available at: <a href=\"https:\/\/www.pharmaceutical-technology.com\/news\/brazil-takeda-dengue-vaccine\/\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow noopener\">https:\/\/www.pharmaceutical-technology.com\/news\/brazil-takeda-dengue-vaccine\/<\/a>. Accessed: February 2024.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[vii] <\/sup>Regulator approves dengue vaccine in Argentina, Buenos Aries Herald, April 27, 2023. Available at&nbsp;: <a href=\"https:\/\/buenosairesherald.com\/society\/health\/regulator-approves-dengue-vaccine-in-argentina\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow noopener\">https:\/\/buenosairesherald.com\/society\/health\/regulator-approves-dengue-vaccine-in-argentina<\/a>. Accessed February 2024.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[viii] <\/sup>Takeda\u2019s dengue vaccine approved in Indonesia for Use Regardless of Prior Dengue Exposure, August 22, 2022,. Available at: <a href=\"https:\/\/www.takeda.com\/newsroom\/newsreleases\/2022\/takedas-qdenga-dengue-tetravalent-vaccine-live-attenuated-approved-in-indonesia-for-use-regardless-of-prior-dengue-exposure\/\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow noopener\">https:\/\/www.takeda.com\/newsroom\/newsreleases\/2022\/takedas-qdenga-dengue-tetravalent-vaccine-live-attenuated-approved-in-indonesia-for-use-regardless-of-prior-dengue-exposure\/<\/a>. Accessed February 2024.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[ix]<\/sup> Food and Drug Administration Ministry of Public Health, Thailand, May 8, 2023. Available at&nbsp;: <a href=\"https:\/\/pertento.fda.moph.go.th\/FDA_SEARCH_DRUG\/SEARCH_DRUG\/pop-up_drug_ex.aspx?Newcode=U1DR2C1072660000411C\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow noopener\">https:\/\/pertento.fda.moph.go.th\/FDA_SEARCH_DRUG\/SEARCH_DRUG\/pop-up_drug_ex.aspx?Newcode=U1DR2C1072660000411C<\/a>. Accessed February 2024.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[x] <\/sup>Media Statement of National Pharmaceutical Regulatory Agency, Ministry of Health Malaysia. Available at&nbsp;: <a href=\"https:\/\/www.npra.gov.my\/easyarticles\/images\/shared\/One-Stop%20Centre\/Kenyataan-Media-KPK--keputusan-mesyuarat-PBKD-393---Zolgensma-dan-QDenga-v7-09022024.pdf\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow noopener\">https:\/\/www.npra.gov.my\/easyarticles\/images\/shared\/One-Stop%20Centre\/Kenyataan-Media-KPK&#8211;keputusan-mesyuarat-PBKD-393&#8212;Zolgensma-dan-QDenga-v7-09022024.pdf<\/a>. Accessed February 2024.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[xi]<\/sup> Huang CY-H, et al. Genetic and phenotypic characterization of manufacturing seeds for tetravalent dengue vaccine (DENVax). PLoS Negl Trop Dis. 2013;7: e2243.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><sup>[xii]<\/sup> Takeda. <a href=\"https:\/\/assets-dam.takeda.com\/raw\/upload\/v1674600772\/legacy-dotcom\/siteassets\/system\/newsroom\/2022\/qdenga\/ema-combined-h-5155-en.pdf\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow noopener\">TAK-003 Summary of Product Characteristics<\/a>. Accessed February 2024.<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u52a0\u901f\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\u4f9b\u5e94 &#8211; \u65b0\u7684\u6218\u7565\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\u5c06\u63d0\u5347\u75ab\u82d7\u751f\u4ea7\u80fd\u529b\uff0c\u4ee5\u652f\u6301\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\u7684\u5168\u7403\u4f9b\u5e94\uff0c\u6269\u5927\u6b66\u7530\u5236\u836f (Takeda)\u5728\u75ab\u82d7\u751f\u4ea7\u9886\u57df\u7684\u8db3\u8ff9\u3002 &#8211; \u5230 2030 \u5e74\uff0c\u8be5\u6218\u7565\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\u5c06\u6bcf\u5e74\u4f9b\u5e94\u591a\u8fbe 5000 \u4e07\u5242\u75ab\u82d7\uff0c\u4ee5\u6ee1\u8db3\u5168\u7403\u516c\u5171\u536b\u751f\u9700\u6c42\u3002 &#8211; \u9aa8\u75db\u70ed\u75c7\u662f\u5168\u7403\u6027\u7684\u516c\u5171\u536b\u751f\u5a01\u80c1\uff0c\u4e3a\u5e2e\u52a9\u51cf\u8f7b\u75be\u75c5\u8d1f\u62c5\uff0c\u6b66\u7530\u5236\u836f (Takeda)\u5c06\u4e0d\u65ad\u52aa\u529b\u6269\u5927\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\u7684\u4f9b\u5e94\u80fd\u529b\u3002 \u65b0\u52a0\u57612024\u5e742\u670827\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; Takeda\u6b66\u7530\u5236\u836f\uff08TSE:4502\/NYSE:TAK\uff09\u4eca\u65e5\u5ba3\u5e03\u4e0e\u5370\u5ea6\u9886\u5148\u7684\u75ab\u82d7\u548c\u751f\u7269\u5236\u54c1\u516c\u53f8 Biological E. Limited \u5efa\u7acb\u6218\u7565\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\uff0c\u5171\u540c\u751f\u4ea7\u6b66\u7530\u65d7\u4e0b\u7684\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7 TAK-003\u3002\u9aa8\u75db\u70ed\u75c7\u8fd1\u5e74\u88ab\u5e7f\u6cdb\u8ba4\u4e3a\u662f\u5168\u7403\u516c\u5171\u536b\u751f\u5a01\u80c1\u4e4b\u4e00\uff0c\u800c\u6b64\u6b21\u5408\u4f5c\u4e0d\u4ec5\u6807\u5fd7\u7740\u5168\u7403\u6297\u51fb\u9aa8\u75db\u70ed\u75c7\u7684\u5173\u952e\u6b65\u9aa4\uff0c\u540c\u65f6\u4e5f\u4e0e\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\uff08WHO\uff09\u6240\u5236\u5b9a\u7684 \u201c\u4e8e2030\u5e74\u5b9e\u73b0\u9aa8\u75db\u70ed\u75c7\u96f6\u81f4\u6b7b\u7387[i].\u201d \u7684\u7279\u5b9a\u75be\u75c5\u76ee\u6807\u4e00\u81f4\u3002 \u6b66\u7530\u4e0eBiological E.\u7684\u5408\u4f5c\u5c06\u5927\u5927\u63d0\u9ad8\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\u7684\u751f\u4ea7\u80fd\u529b\uff0c\u786e\u4fdd\u75ab\u82d7\u5728\u5168\u7403\u7684\u53ef\u6301\u7eed\u4f9b\u5e94\u3002Biological E. \u5c06\u6269\u5927\u4ea7\u80fd\uff0c\u5176\u5e74\u4ea7\u91cf\u5c06\u53ef\u8fbe\u5230\u6bcf\u5e74 5000 \u4e07\u5242\uff0c\u4ece\u800c\u52a0\u5feb\u6b66\u7530\u5236\u836f\u5728\u4e3a\u6765\u5341\u5e74\u5185\u5b9e\u73b0\u5e74\u4ea7 1 \u4ebf\u5242\u7684\u76ee\u6807\u3002 \u7279\u4f26\u7518\u7eb3\u90a6 (Telangana) \u9996\u5e2d\u90e8\u957f&nbsp;Sri Anumula Revanth Reddy\uff0c\u5728\u7279\u4f26\u7518\u7eb3\u90a6\u653f\u5e9c\u7ec4\u7ec7\u7684\u5730\u533a\u751f\u547d\u79d1\u5b66\u4e0e\u533b\u7597\u4fdd\u5065\u8bba\u575b BioAsia 2024 \u4e0a\u5ba3\u5e03\u4e86\u53cc\u65b9\u7684\u5408\u4f5c\u5173\u7cfb\u3002\u4ed6\u5728\u53d1\u8a00\u4e2d\u6307\u51fa\uff1a&quot;\u6211\u4eec\u5f88\u9ad8\u5174\u6b66\u7530\u5236\u836f\u548cBiological E.\u5408\u4f5c\u751f\u4ea7\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\u7684\u8bbe\u65bd\u5c06\u843d\u6237\u7279\u4f26\u7518\u7eb3\u90a6\uff08Telangana\uff09\u7684\u6d77\u5fb7\u62c9\u5df4\uff08Hyderabad\uff09\u3002\u7279\u4f26\u7518\u7eb3\u90a6\u4e3a\u751f\u547d\u79d1\u5b66\uff0c\u7279\u522b\u662f\u75ab\u82d7\u548c\u751f\u7269\u5236\u5242\u7684\u7814\u53d1\u548c\u5236\u9020\u63d0\u4f9b\u4e86\u826f\u597d\u7684\u73af\u5883\u3002\u6211\u5f88\u9ad8\u5174\u8fd9\u4e2a\u5de5\u5382\u80fd\u52a0\u901f\u75ab\u82d7\u5728\u5370\u5ea6\u53ca\u5176\u4ed6\u9aa8\u75db\u70ed\u75c7\u6d41\u884c\u56fd\u5bb6\u53ca\u5730\u533a\u7684\u4f9b\u5e94\u3002&quot; \u7279\u4f26\u7518\u7eb3\u90a6\u5de5\u4e1a\u548c\u5546\u4e1a\u90e8\u957f Sri Duddilla Sridhar Babu \u6307\u51fa\uff1a&quot;\u900f\u8fc7\u6b66\u7530\u5236\u836f\u7684\u6280\u672f\u4e13\u957f\u548cBiological E.\u7684\u5236\u9020\u80fd\u529b\uff0c\u5c06\u6709\u52a9\u4e8e\u63d0\u9ad8\u9aa8\u75db\u70ed\u75c7\u75ab\u82d7\u7684\u53ef\u53ca\u6027\u548c\u53ef\u8d1f\u62c5\u6027\uff0c\u4e3a\u5370\u5ea6\u7684\u533b\u7597\u4fdd\u5065\u7684\u97e7\u529b\u548c\u672a\u6765\u51c6\u5907\u505a\u51fa\u8d21\u732e\u3002\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u652f\u6301\u8fd9\u6b21\u7ed3\u5408\u79d1\u5b66\u3001\u653f\u5e9c\u548c\u4ea7\u4e1a\u7684\u5408\u4f5c\uff0c\u63a8\u52a8\u548c\u6269\u5927\u521b\u65b0\uff0c\u5b9e\u73b0\u5168\u6c11\u5065\u5eb7\u8986\u76d6\u3002&quot; \u6b66\u7530\u5236\u836f\u5168\u7403\u75ab\u82d7\u4e8b\u4e1a\u90e8\u603b\u88c1\u3001\u533b\u5b66\u535a\u58ebGary Dubin\u8868\u793a\uff1a\u201c\u6b66\u7530\u9aa8\u75db\u70ed\u75c7\u9879\u76ee\u7684\u957f\u671f\u76ee\u6807\u662f\u4e3a\u90a3\u4e9b\u53ef\u80fd\u53d7\u76ca\u4e8e\u514d\u75ab\u63a5\u79cd\u7684\u9ad8\u5371\u4eba\u7fa4\u63d0\u4f9bTAK-003\u75ab\u82d7\u3002\u5728\u8fc7\u53bb\u4e00\u5e74\u91cc\uff0c\u6211\u4eec\u4e0d\u4ec5\u6210\u529f\u5728\u79c1\u8425\u5e02\u573a\u63a8\u51faTAK-003\uff0c\u6700\u8fd1\u66f4\u5728\u4e00\u90e8\u5206\u516c\u5171\u9879\u76ee\u4e2d\u63a8\u51faTAK-003\uff0c\u540c\u65f6\u4e0e\u5404\u754c\u5408\u4f5c\u4f19\u4f34\u4e00\u8d77\u4e3a\u52a0\u5f3a\u5bf9\u516c\u5171\u536b\u751f\u5065\u5eb7\u7684\u7ef4\u62a4\u3002\u4eca\u65e5\uff0c\u6211\u4eec\u5f88\u81ea\u8c6a\u5730\u5ba3\u5e03\u4e0e Biological E. Limited \u6b63\u5f0f\u6210\u4e3a\u6218\u7565\u751f\u4ea7\u5408\u4f5c\u4f19\u4f34\u3002\u8be5\u516c\u53f8\u5728\u75ab\u82d7\u751f\u4ea7\u65b9\u9762\u62e5\u6709\u6df1\u539a\u7684\u4e13\u4e1a\u77e5\u8bc6\uff0c\u5e76\u957f\u671f\u652f\u6301\u4e16\u754c\u5404\u5730\u7684\u516c\u5171\u536b\u751f\u9879\u76ee\u3002\u901a\u8fc7\u5927\u5e45\u63d0\u9ad8&hellip; <a class=\"read-more\" href=\"https:\/\/www.xinwengao.com\/cn\/pr\/20240227170900106232\">Read More<\/a><\/p>\n","protected":false},"author":556,"featured_media":0,"comment_status":"close","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1965],"tags":[],"class_list":["post-106232","post","type-post","status-publish","format-standard","hentry","category-partnerships"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/106232","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/comments?post=106232"}],"version-history":[{"count":1,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/106232\/revisions"}],"predecessor-version":[{"id":106233,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/posts\/106232\/revisions\/106233"}],"wp:attachment":[{"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/media?parent=106232"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/categories?post=106232"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.xinwengao.com\/cn\/wp-json\/wp\/v2\/tags?post=106232"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}