{"id":100689,"date":"2023-12-08T11:10:00","date_gmt":"2023-12-08T04:10:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/20231208111000100689"},"modified":"2023-12-08T22:00:41","modified_gmt":"2023-12-08T14:00:41","slug":"%e5%9f%ba%e7%9f%b3%e8%8d%af%e4%b8%9a%e5%ae%a3%e5%b8%83%e6%8b%a9%e6%8d%b7%e7%be%8e%ef%bc%88%e8%88%92%e6%a0%bc%e5%88%a9%e5%8d%95%e6%8a%97%e6%b3%a8%e5%b0%84%e6%b6%b2%ef%bc%89%e4%b8%80%e7%ba%bf","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/20231208111000100689","title":{"rendered":"\u57fa\u77f3\u836f\u4e1a\u5ba3\u5e03\u62e9\u6377\u7f8e\u00ae\uff08\u8212\u683c\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff09\u4e00\u7ebf\u6cbb\u7597\u98df\u7ba1\u9cde\u764c\u7684\u65b0\u9002\u5e94\u75c7\u5728\u4e2d\u56fd\u83b7\u6279"},"content":{"rendered":"<ul type=\"disc\">\n<li>\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u662f\u5168\u7403\u9996\u4e2a\u83b7\u6279\u8054\u5408\u6c1f\u5c3f\u5627\u5576\u7c7b\u548c\u94c2\u7c7b\u5316\u7597\u836f\u7269\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u4e0d\u53ef\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u3001\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u98df\u7ba1\u9cde\u764c\u9002\u5e94\u75c7\u7684PD-L1\u5355\u6297\u3002<\/li>\n<li>\u8fd9\u662f\u7ee7III\u671f\u3001IV\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4ee5\u53ca\u590d\u53d1\u6216\u96be\u6cbb\u6027\u7ed3\u5916NK\/T\u7ec6\u80de\u6dcb\u5df4\u7624\u540e\uff0c\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u5728\u4e2d\u56fd\u83b7\u6279\u7684\u7b2c\u56db\u9879\u9002\u5e94\u75c7\uff0c\u4e5f\u662f\u57fa\u77f3\u836f\u4e1a\u81ea\u6210\u7acb\u4ee5\u6765\u83b7\u5f97\u7684\u7b2c13\u9879\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u7684\u6279\u51c6\u3002<\/li>\n<li>GEMSTONE-304\u7814\u7a76\u5df2\u8fbe\u5230\u9884\u8bbe\u53cc\u7ec8\u70b9\u3002\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u8054\u5408\u6c1f\u5c3f\u5627\u5576\u548c\u987a\u94c2\u5728\u4e0d\u53ef\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u3001\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u98df\u7ba1\u9cde\u764c\u60a3\u8005\u7684\u4e00\u7ebf\u6cbb\u7597\u4e2d\u663e\u8457\u6539\u5584\u4e86\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u548c\u603b\u751f\u5b58\u671f\uff0c\u5dee\u5f02\u5177\u6709\u7edf\u8ba1\u5b66\u663e\u8457\u6027\u4e0e\u4e34\u5e8a\u610f\u4e49\u3002<\/li>\n<\/ul>\n<p><p><span class=\"legendSpanClass\">\u82cf\u5dde<\/span><span class=\"legendSpanClass\">2023\u5e7412\u67088\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212;&nbsp;\u57fa\u77f3\u836f\u4e1a\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801\uff1a2616\uff09\uff0c\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u7814\u7a76\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u521b\u65b0\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u53ca\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\u7684\u9886\u5148\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u5e03\uff0c\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\uff08\u8212\u683c\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff09\u8054\u5408\u6c1f\u5c3f\u5627\u5576\u7c7b\u548c\u94c2\u7c7b\u5316\u7597\u836f\u7269\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u4e0d\u53ef\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u3001\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u98df\u7ba1\u9cde\u764c\u7684\u65b0\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\u5df2\u83b7\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\u3002\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u6210\u4e3a\u5168\u7403\u9996\u4e2a\u9488\u5bf9\u8be5\u9002\u5e94\u75c7\u83b7\u6279\u7684PD-L1\u5355\u6297\u3002<\/p>\n<p>\u57fa\u77f3\u836f\u4e1a\u9996\u5e2d\u6267\u884c\u5b98\u6768\u5efa\u65b0\u535a\u58eb\u8868\u793a\uff1a&quot;\u6211\u4eec\u975e\u5e38\u9ad8\u5174\u6536\u83b7\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u7684\u7b2c\u56db\u9879\u9002\u5e94\u75c7\uff0c\u6b64\u6b21\u83b7\u6279\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u98df\u7ba1\u9cde\u764c\u60a3\u8005\uff0c\u8fdb\u4e00\u6b65\u8bc1\u5b9e\u4e86\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u7684\u4e34\u5e8a\u4ef7\u503c\u548c\u6f5c\u529b\u3002\u9664\u5df2\u83b7\u6279\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u7ed3\u5916NK\/T\u7ec6\u80de\u6dcb\u5df4\u7624\u4ee5\u53ca\u98df\u7ba1\u9cde\u764c\u9002\u5e94\u75c7\u5916\uff0c\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u53e6\u6709\u4e00\u9879\u4e00\u7ebf\u6cbb\u7597\u80c3\u764c\u7684\u9002\u5e94\u75c7\u6b63\u5728\u5ba1\u8bc4\u4e2d\uff0c\u6211\u4eec\u5c06\u4e0eNMPA\u4fdd\u6301\u987a\u7545\u6c9f\u901a\uff0c\u4ee5\u671f\u5c3d\u65e9\u5728\u4e2d\u56fd\u83b7\u5f97\u8be5\u9002\u5e94\u75c7\u7684\u6279\u51c6\u3002\u6211\u4eec\u4e5f\u5c06\u4e0e\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u3001\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u7b49\u5168\u7403\u76d1\u7ba1\u673a\u6784\u7d27\u5bc6\u6c9f\u901a\uff0c\u8fdb\u4e00\u6b65\u63a8\u52a8\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u5728\u6b27\u7f8e\u4ee5\u53ca\u5168\u7403\u5176\u4ed6\u5730\u533a\u7684\u6ce8\u518c\u4e0a\u5e02\u8fdb\u7a0b\u3002\u671f\u5f85\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u80fd\u591f\u9020\u798f\u5168\u7403\u66f4\u591a\u98df\u7ba1\u9cde\u764c\u60a3\u8005\u3002&quot;<\/p>\n<p>\u62e9\u6377\u7f8e<sup>&reg;<\/sup>GEMSTONE-304\u7814\u7a76\u4e3b\u8981\u7814\u7a76\u8005\u3001\u540c\u6d4e\u5927\u5b66\u9644\u5c5e\u4e1c\u65b9\u533b\u9662\u80bf\u7624\u533b\u5b66\u90e8\u4e3b\u4efb\u674e\u8fdb\u6559\u6388\u8868\u793a\uff1a&quot;\u98df\u7ba1\u764c\u662f\u6211\u56fd\u9ad8\u53d1\u6076\u6027\u80bf\u7624\uff0c\u4ece\u75c5\u7406\u7c7b\u578b\u4e0a\u770b\uff0c\u98df\u7ba1\u9cde\u764c\u6700\u4e3a\u5e38\u89c1\u3002\u5728\u4e34\u5e8a\u4e2d\uff0c\u7ea670%\u98df\u7ba1\u764c\u60a3\u8005\u5728\u521d\u6b21\u786e\u8bca\u65f6\u5df2\u53d1\u5c55\u4e3a\u5c40\u90e8\u665a\u671f\u6216\u6709\u8fdc\u5904\u8f6c\u79fb\uff0c\u5931\u53bb\u4e86\u6839\u6cbb\u6027\u624b\u672f\u5207\u9664\u7684\u673a\u4f1a\u3002\u5373\u4f7f\u5728\u53ef\u624b\u672f\u7684\u98df\u7ba1\u764c\u4e2d\uff0c50%-60%\u7684\u60a3\u8005\u5728\u672f\u540e\u4f1a\u590d\u53d1\u6216\u53d1\u751f\u8fdc\u5904\u8f6c\u79fb\u3002GEMSTONE-304\u7814\u7a76\u663e\u793a\uff0c\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u98df\u7ba1\u9cde\u764c\uff0c\u76f8\u8f83\u4e8e\u5316\u7597\u663e\u8457\u6539\u5584\u4e86\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS) \u548c\u603b\u751f\u5b58\u671f\uff08OS\uff09\uff0c\u4e14\u5b89\u5168\u6027\u826f\u597d\u3002\u6211\u4eec\u76f8\u4fe1\u6b64\u6b21\u83b7\u6279\u5c06\u4e3a\u5e7f\u5927\u665a\u671f\u98df\u7ba1\u9cde\u764c\u60a3\u8005\u5e26\u6765\u65b0\u7684\u4e00\u7ebf\u6cbb\u7597\u9009\u62e9\u3002&quot;<\/p>\n<p>\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u6b64\u6b21\u9002\u5e94\u75c7\u83b7\u6279\u662f\u57fa\u4e8eGEMSTONE-304\u7814\u7a76\uff0c\u8be5\u7814\u7a76\u662f\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u591a\u4e2d\u5fc3\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684III\u671f\u6ce8\u518c\u6027\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u65e8\u5728\u8bc4\u4f30\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u8054\u5408\u6c1f\u5c3f\u5627\u5576\u53ca\u987a\u94c2\u4f5c\u4e3a\u4e0d\u53ef\u624b\u672f\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u3001\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u98df\u7ba1\u9cde\u764c\u4e00\u7ebf\u6cbb\u7597\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002\u8be5\u8bd5\u9a8c\u7684\u4e3b\u8981\u7814\u7a76\u7ec8\u70b9\u4e3a\u76f2\u6001\u72ec\u7acb\u4e2d\u5fc3\u5ba1\u9605\u59d4\u5458\u4f1a\uff08BICR\uff09\u8bc4\u4f30\u7684\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS) \u548c\u603b\u751f\u5b58\u671f\uff08OS\uff09\uff0c\u6b21\u8981\u7814\u7a76\u7ec8\u70b9\u5305\u62ec\u7814\u7a76\u8005\u8bc4\u4f30\u7684PFS\u3001BICR\u548c\u7814\u7a76\u8005\u8bc4\u4f30\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u53ca\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff08DoR\uff09\u7b49\u3002<\/p>\n<p>\u6b64\u524d\uff0cGEMSTONE-304\u7814\u7a76\u6570\u636e\u5df2\u57282023\u5e74ESMO\u4e16\u754c\u80c3\u80a0\u9053\u80bf\u7624\u5927\u4f1a\uff08ESMO GI 2023\uff09 \u4ee5\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\u3002\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0cGEMSTONE-304\u7814\u7a76\u5df2\u8fbe\u5230\u9884\u8bbe\u53cc\u7ec8\u70b9\u3002\u4e0e\u5b89\u6170\u5242\u8054\u5408\u5316\u7597\u76f8\u6bd4\uff0c\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u8054\u5408\u5316\u7597\u660e\u663e\u6539\u5584\u4e86BICR\u8bc4\u4f30\u7684PFS\u548cOS\uff0c\u4e14\u5dee\u5f02\u5177\u6709\u7edf\u8ba1\u5b66\u663e\u8457\u6027\u4e0e\u4e34\u5e8a\u610f\u4e49\u3002\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u8054\u5408\u5316\u7597\u5177\u6709\u826f\u597d\u7684\u8010\u53d7\u6027\u548c\u5b89\u5168\u6027\uff0c\u672a\u53d1\u73b0\u65b0\u7684\u5b89\u5168\u6027\u98ce\u9669\uff0c\u5b89\u5168\u6027\u4e0e\u65e2\u5f80\u62a5\u9053\u7684\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u76f8\u5173\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u4e00\u81f4\u3002\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u6cbb\u7597\u7ec4\u4e0e\u5b89\u6170\u5242\u7ec4\u60a3\u8005BICR\u8bc4\u4f30\u7684\u4e2d\u4f4dPFS\u4e3a6.2\u4e2a\u6708 vs 5.4\u4e2a\u6708\uff0c\u98ce\u9669\u6bd4\uff08HR\uff09=0.67 (95% CI, 0.54-0.82)\uff0cP\u503c=0.0002\u3002\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u6cbb\u7597\u7ec4\u4e0e\u5b89\u6170\u5242\u7ec4\u60a3\u8005\u4e2d\u4f4dOS\u4e3a15.3\u4e2a\u6708vs 11.5\u4e2a\u6708\uff0cHR=0.70 (95% CI, 0.55-0.90)&nbsp;\uff0cP\u503c=0.0076\u3002\u4e9a\u7ec4\u5206\u6790\u663e\u793a\uff0cPD-L1\u8868\u8fbe\u72b6\u6001\u7b49\u5404\u9884\u8bbe\u4e9a\u7ec4\u548c\u603b\u4f53\u4eba\u7fa4\u7684\u83b7\u76ca\u8d8b\u52bf\u57fa\u672c\u4e00\u81f4\u3002BICR\u8bc4\u4f30\u7684ORR\u4e3a60.1% vs 45.2%\uff0c\u5dee\u503c\u4e3a14.9%\uff1bDoR\u4e3a6.0\u4e2a\u6708 vs 4.5\u4e2a\u6708\u3002<\/p>\n<p><b>\u5173\u4e8e\u98df\u7ba1\u764c<\/b><\/p>\n<p>\u98df\u7ba1\u764c\u662f\u5168\u7403\u5e38\u89c1\u7684\u764c\u75c7\u4e4b\u4e00\uff0c\u636eGLOBOCAN 2020\u6570\u636e\uff0c2020\u5e74\u5168\u7403\u65b0\u53d1\u98df\u7ba1\u764c\u7684\u75c5\u4f8b\u8d85\u8fc760\u4e07\u4f8b\uff08\u98df\u7ba1\u9cde\u764c\u7ea6\u536085%\uff09\uff0c\u6b7b\u4ea1\u75c5\u4f8b\u8fbe54.4\u4e07\u4f8b\uff0c\u662f\u5168\u7403\u7b2c9\u4f4d\u5e38\u89c1\u764c\u75c7\u548c\u7b2c6\u4f4d\u764c\u75c7\u6b7b\u4ea1\u539f\u56e0\u3002\u4e2d\u56fd\u6bcf\u5e74\u98df\u7ba1\u764c\u53d1\u75c5\u4eba\u6570\u5360\u5168\u7403\u4e00\u534a\u4ee5\u4e0a\uff0c\u7ea690%\u4e3a\u98df\u7ba1\u9cde\u764c\uff0c\u4e14\u591a\u6570\u98df\u7ba1\u9cde\u764c\u60a3\u8005\u5728\u786e\u8bca\u65f6\u5df2\u4e3a\u665a\u671f\uff0c\u5931\u53bb\u6839\u6cbb\u6027\u6cbb\u7597\u7684\u673a\u4f1a\u3002<\/p>\n<p><b>\u5173\u4e8e\u62e9\u6377\u7f8e<\/b><b><sup>&reg;<\/sup><\/b><b>\uff08\u8212\u683c\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff09<\/b><\/p>\n<p>\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u662f\u7531\u57fa\u77f3\u836f\u4e1a\u7814\u53d1\u7684\u6297PD-L1\u5355\u514b\u9686\u6297\u4f53\uff0c\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u7684\u5f00\u53d1\u662f\u57fa\u4e8e\u7f8e\u56fdLigand\u516c\u53f8\u6388\u6743\u5f15\u8fdb\u7684OmniRat<sup>&reg;<\/sup>\u8f6c\u57fa\u56e0\u52a8\u7269\u5e73\u53f0\u3002\u8be5\u5e73\u53f0\u53ef\u4e00\u7ad9\u5f0f\u4ea7\u751f\u5168\u4eba\u6e90\u6297\u4f53\u3002\u4f5c\u4e3a\u4e00\u79cd\u5168\u4eba\u6e90\u5168\u957f\u6297PD-L1\u5355\u514b\u9686\u6297\u4f53\uff0c\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u662f\u4e00\u79cd\u6700\u63a5\u8fd1\u4eba\u4f53\u7684\u5929\u7136G\u578b\u514d\u75ab\u7403\u86cb\u767d4\uff08IgG4\uff09\u5355\u6297\u836f\u7269\u3002\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u5728\u60a3\u8005\u4f53\u5185\u4ea7\u751f\u514d\u75ab\u539f\u6027\u53ca\u76f8\u5173\u6bd2\u6027\u7684\u98ce\u9669\u66f4\u4f4e\uff0c\u8fd9\u4f7f\u5f97\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u4e0e\u540c\u7c7b\u836f\u7269\u76f8\u6bd4\u5177\u6709\u72ec\u7279\u4f18\u52bf\u3002<\/p>\n<p>\u76ee\u524d\uff0cNMPA\u5df2\u6279\u51c6\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u56db\u9879\u9002\u5e94\u75c7\uff1a<\/p>\n<ul type=\"disc\">\n<li>\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u8f6c\u79fb\u6027\u9cde\u72b6\u548c\u975e\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\uff1b<\/li>\n<li>\u6cbb\u7597\u540c\u6b65\u6216\u5e8f\u8d2f\u653e\u5316\u7597\u540e\u672a\u51fa\u73b0\u75be\u75c5\u8fdb\u5c55\u7684\u3001\u4e0d\u53ef\u5207\u9664\u3001III\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\uff1b<\/li>\n<li>\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u7ed3\u5916NK\/T\u7ec6\u80de\u6dcb\u5df4\u7624\u60a3\u8005\uff1b<\/li>\n<li>\u8054\u5408\u6c1f\u5c3f\u5627\u5576\u7c7b\u548c\u94c2\u7c7b\u5316\u7597\u836f\u7269\u4e00\u7ebf\u6cbb\u7597\u4e0d\u53ef\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\uff0c\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u98df\u7ba1\u9cde\u764c\u60a3\u8005\u3002<\/li>\n<\/ul>\n<p>\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u7528\u4e8e\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u65e0\u6cd5\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u80c3\/\u80c3\u98df\u7ba1\u7ed3\u5408\u90e8\u817a\u764c\u9002\u5e94\u75c7\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7\u5df2\u83b7NMPA\u53d7\u7406\uff0c\u76ee\u524d\u6b63\u5728\u5ba1\u8bc4\u4e2d\u3002<\/p>\n<p>\u6b64\u5916\uff0c\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u548c\u82f1\u56fd\u836f\u54c1\u548c\u533b\u7597\u4fdd\u5065\u7528\u54c1\u7ba1\u7406\u5c40\uff08MHRA\uff09\u5747\u5df2\u53d7\u7406\u8212\u683c\u5229\u5355\u6297\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u8f6c\u79fb\u6027NSCLC\u7684\u4e0a\u5e02\u8bb8\u53ef\u7533\u8bf7\u3002\u76ee\u524d\uff0c\u4e24\u9879\u7533\u8bf7\u6b63\u5728\u5ba1\u8bc4\u8fc7\u7a0b\u4e2d\u3002<\/p>\n<p>\u57fa\u77f3\u836f\u4e1a\u4e0e\u8f89\u745e\u8fbe\u6210\u6218\u7565\u5408\u4f5c\uff0c\u5176\u4e2d\u5305\u62ec\u57fa\u77f3\u836f\u4e1a\u4e0e\u8f89\u745e\u6295\u8d44\u5c31\u62e9\u6377\u7f8e<sup>&reg;<\/sup>\u5728\u4e2d\u56fd\u5927\u9646\u5730\u533a\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\uff0c\u4ee5\u53ca\u57fa\u77f3\u836f\u4e1a\u4e0e\u8f89\u745e\u6295\u8d44\u5c06\u66f4\u591a\u80bf\u7624\u4ea7\u54c1\u5f15\u5165\u5927\u4e2d\u534e\u5730\u533a\u7684\u5408\u4f5c\u6846\u67b6\u8fbe\u6210\u6218\u7565\u5408\u4f5c\u7b49\u3002<\/p>\n<p><b>\u5173\u4e8e\u57fa\u77f3\u836f\u4e1a<\/b><\/p>\n<p>\u57fa\u77f3\u836f\u4e1a\uff08\u9999\u6e2f\u8054\u4ea4\u6240\u4ee3\u7801: 2616\uff09\u662f\u4e00\u5bb6\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u7814\u7a76\u5f00\u53d1\u53ca\u5546\u4e1a\u5316\u521b\u65b0\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u53ca\u7cbe\u51c6\u6cbb\u7597\u836f\u7269\uff0c\u4ee5\u6ee1\u8db3\u4e2d\u56fd\u548c\u5168\u7403\u764c\u75c7\u60a3\u8005\u7684\u6bb7\u5207\u533b\u7597\u9700\u6c42\u3002\u6210\u7acb\u4e8e2015\u5e74\u5e95\uff0c\u57fa\u77f3\u836f\u4e1a\u5df2\u96c6\u7ed3\u4e86\u4e00\u652f\u5728\u65b0\u836f\u7814\u53d1\u3001\u4e34\u5e8a\u7814\u7a76\u4ee5\u53ca\u5546\u4e1a\u8fd0\u8425\u65b9\u9762\u62e5\u6709\u4e30\u5bcc\u7ecf\u9a8c\u7684\u7ba1\u7406\u56e2\u961f\u3002\u516c\u53f8\u4ee5\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u8054\u5408\u7597\u6cd5\u4e3a\u6838\u5fc3\uff0c\u5efa\u7acb\u4e86\u4e00\u676114\u79cd\u80bf\u7624\u5019\u9009\u836f\u7269\u7ec4\u6210\u7684\u4e30\u5bcc\u4ea7\u54c1\u7ba1\u7ebf\u3002\u76ee\u524d\uff0c\u57fa\u77f3\u836f\u4e1a\u5df2\u7ecf\u83b7\u5f97\u4e8613\u9879\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u7684\u6279\u51c6\u3002\u591a\u6b3e\u540e\u671f\u5019\u9009\u836f\u7269\u6b63\u5904\u4e8e\u5173\u952e\u6027\u4e34\u5e8a\u8bd5\u9a8c\u6216\u6ce8\u518c\u9636\u6bb5\u3002\u57fa\u77f3\u836f\u4e1a\u7684\u613f\u666f\u662f\u6210\u4e3a\u4eab\u8a89\u5168\u7403\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u5f15\u9886\u653b\u514b\u764c\u75c7\u4e4b\u8def\u3002<\/p>\n<p>\u5982\u9700\u4e86\u89e3\u6709\u5173\u57fa\u77f3\u836f\u4e1a\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1a<a href=\"http:\/\/www.cstonepharma.com\/\" target=\"_blank\" rel=\"nofollow noopener\">www.cstonepharma.com<\/a>\u3002<\/p>\n<p><b>\u524d\u77bb\u6027\u58f0\u660e<\/b><\/p>\n<p>\u672c\u6587\u6240\u4f5c\u51fa\u7684\u524d\u77bb\u6027\u9648\u8ff0\u4ec5\u4e0e\u672c\u6587\u4f5c\u51fa\u8be5\u9648\u8ff0\u5f53\u65e5\u7684\u4e8b\u4ef6\u6216\u8d44\u6599\u6709\u5173\u3002\u9664\u6cd5\u5f8b\u89c4\u5b9a\u5916\uff0c\u4e8e\u4f5c\u51fa\u524d\u77bb\u6027\u9648\u8ff0\u5f53\u65e5\u4e4b\u540e\uff0c\u65e0\u8bba\u662f\u5426\u51fa\u73b0\u65b0\u8d44\u6599\u3001\u672a\u6765\u4e8b\u4ef6\u6216\u5176\u4ed6\u60c5\u51b5\uff0c\u6211\u4eec\u5e76\u65e0\u8d23\u4efb\u66f4\u65b0\u6216\u516c\u5f00\u4fee\u6539\u4efb\u4f55\u524d\u77bb\u6027\u9648\u8ff0\u53ca\u9884\u6599\u4e4b\u5916\u7684\u4e8b\u4ef6\u3002\u8bf7\u7ec6\u9605\u672c\u6587\uff0c\u5e76\u7406\u89e3\u6211\u4eec\u7684\u5b9e\u9645\u672a\u6765\u4e1a\u7ee9\u6216\u8868\u73b0\u53ef\u80fd\u4e0e\u9884\u671f\u6709\u91cd\u5927\u5dee\u5f02\u3002\u672c\u6587\u5185\u6240\u6709\u9648\u8ff0\u4e43\u672c\u6587\u7ae0\u520a\u53d1\u65e5\u671f\u4f5c\u51fa\uff0c\u53ef\u80fd\u56e0\u672a\u6765\u53d1\u5c55\u800c\u51fa\u73b0<span id=\"spanHghltc90c\">\u53d8\u52a8\u3002<\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u62e9\u6377\u7f8e&reg;\u662f\u5168\u7403\u9996\u4e2a\u83b7\u6279\u8054\u5408\u6c1f\u5c3f\u5627\u5576\u7c7b\u548c\u94c2\u7c7b\u5316\u7597\u836f\u7269\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u4e0d\u53ef\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u3001\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u98df\u7ba1\u9cde\u764c\u9002\u5e94\u75c7\u7684PD-L1\u5355\u6297\u3002 \u8fd9\u662f\u7ee7III\u671f\u3001IV\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4ee5\u53ca\u590d\u53d1\u6216\u96be\u6cbb\u6027\u7ed3\u5916NK\/T\u7ec6\u80de\u6dcb\u5df4\u7624\u540e\uff0c\u62e9\u6377\u7f8e&reg;\u5728\u4e2d\u56fd\u83b7\u6279\u7684\u7b2c\u56db\u9879\u9002\u5e94\u75c7\uff0c\u4e5f\u662f\u57fa\u77f3\u836f\u4e1a\u81ea\u6210\u7acb\u4ee5\u6765\u83b7\u5f97\u7684\u7b2c13\u9879\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u7684\u6279\u51c6\u3002 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