{"id":100021,"date":"2023-12-04T12:12:00","date_gmt":"2023-12-04T05:12:00","guid":{"rendered":"https:\/\/www.xinwengao.com\/cn\/pr\/20231204121200100021"},"modified":"2023-12-04T22:00:50","modified_gmt":"2023-12-04T14:00:50","slug":"%e7%bb%bf%e5%8f%b6%e5%88%b6%e8%8d%af%e5%ae%a3%e5%b8%83%e5%88%9b%e6%96%b0%e8%8d%af%e8%8a%a6%e6%af%94%e6%9b%bf%e5%ae%9a%e5%9c%a8%e4%b8%ad%e5%9b%bd%e6%be%b3%e9%97%a8%e8%8e%b7%e6%89%b9%e4%b8%8a%e5%b8%82","status":"publish","type":"post","link":"https:\/\/www.xinwengao.com\/cn\/pr\/20231204121200100021","title":{"rendered":"\u7eff\u53f6\u5236\u836f\u5ba3\u5e03\u521b\u65b0\u836f\u82a6\u6bd4\u66ff\u5b9a\u5728\u4e2d\u56fd\u6fb3\u95e8\u83b7\u6279\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6027\u5c0f\u7ec6\u80de\u80ba\u764c"},"content":{"rendered":"

\u4e0a\u6d77<\/span>2023\u5e7412\u67084\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u7eff\u53f6\u5236\u836f\u96c6\u56e2\u5ba3\u5e03\uff0c\u6ce8\u5c04\u7528\u82a6\u6bd4\u66ff\u5b9a\u5df2\u6b63\u5f0f\u83b7\u5f97\u4e2d\u56fd\u6fb3\u95e8\u836f\u7269\u76d1\u7763\u7ba1\u7406\u5c40\u7684\u4e0a\u5e02\u6279\u51c6\uff0c\u7528\u4e8e\u6cbb\u7597\u63a5\u53d7\u94c2\u7c7b\u836f\u7269\u5316\u7597\u671f\u95f4\u6216\u671f\u540e\u51fa\u73b0\u75be\u75c5\u8fdb\u5c55\u7684\u8f6c\u79fb\u6027\u5c0f\u7ec6\u80de\u80ba\u764c\uff08SCLC\uff09\u6210\u4eba\u60a3\u8005\u3002<\/p>\n

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\u82a6\u6bd4\u66ff\u5b9a\u5728\u4e2d\u56fd\u6fb3\u95e8\u7684\u4e0a\u5e02\u6279\u51c6\uff0c\u4e3b\u8981\u57fa\u4e8e\u5176\u5728\u4e2d\u56fd\u53ca\u6d77\u5916\u5f00\u5c55\u7684\u4e24\u9879\u4e34\u5e8a\u7814\u7a76\u3002\u5176\u4e2d\uff0c\u5728\u6d77\u5916\u5f00\u5c55\u7684\u7814\u7a76\u4e3a\u4e00\u9879\u82a6\u6bd4\u66ff\u5b9a\u5355\u836f\u6cbb\u7597105\u4f8b\u63a5\u53d7\u94c2\u7c7b\u836f\u7269\u5316\u7597\u540e\u51fa\u73b0\u75be\u75c5\u8fdb\u5c55\u7684SCLC\u6210\u5e74\u60a3\u8005\u7684\u5f00\u653e\u3001\u591a\u4e2d\u5fc3\u3001\u5355\u81c2\u3001II\u671f\u7bee\u5b50\u8bd5\u9a8c\u3002\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff1a\u63a5\u53d7\u82a6\u6bd4\u66ff\u5b9a\u6cbb\u7597\u7684\u60a3\u8005\u603b\u6709\u6548\u7387\uff08ORR\uff09\u4e3a35.2%\uff1b\u5176\u4e2d\uff0c\u5316\u7597\u654f\u611f\u578b\u60a3\u8005\uff08\u505c\u7597\u81f3\u590d\u53d1\u95f4\u9694\uff08CTFI\uff09\u226590\u5929\uff09\u7684ORR\u8fbe\u523045%\uff0c\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08mPFS\uff09\u4e3a4.6\u4e2a\u6708\uff0c\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\uff08mOS\uff09\u4e3a11.9\u4e2a\u6708\u3002<\/p>\n

\u82a6\u6bd4\u66ff\u5b9a\u5728\u4e2d\u56fd\u5f00\u5c55\u7684\u5355\u81c2\u3001\u5305\u542b\u5242\u91cf\u9012\u589e\u53ca\u6269\u5c55\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u7528\u4e8e\u8bc4\u4f30\u8be5\u836f\u7269\u5728\u5305\u62ec\u590d\u53d1\u6027SCLC\u5728\u5185\u7684\u665a\u671f\u5b9e\u4f53\u7624\u4e2d\u56fd\u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u3001PK\u7279\u5f81\u548c\u521d\u6b65\u7597\u6548\u3002\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff1a\u5728\u590d\u53d1\u6027SCLC\u53d7\u8bd5\u8005\u4e2d\uff0c\u7531\u72ec\u7acb\u8bc4\u4f30\u59d4\u5458\u4f1a\u8bc4\u4f30\u7684ORR\u4e3a45.5%\u3001mPFS\u4e3a5.6\u4e2a\u6708\uff0cmOS\u4e3a11.0\u4e2a\u6708\u3002\u7814\u7a76\u7ed3\u679c\u4ea6\u63d0\u793a\uff1a\u82a6\u6bd4\u66ff\u5b9a\u4e8c\u7ebf\u6cbb\u7597\u4e2d\u56fdSCLC\u60a3\u8005\u5177\u6709\u663e\u8457\u7684\u6297\u80bf\u7624\u7597\u6548\u53ca\u53ef\u63a7\u7684\u5b89\u5168\u6027\uff0c\u5176\u5728\u4e2d\u56fd\u4eba\u7fa4\u4e2d\u7684\u7597\u6548\u4e0e\u56fd\u5916II\u671f\u4e34\u5e8a\u8bd5\u9a8cSCLC\u961f\u5217\u7684\u7597\u6548\u7ed3\u679c\u6709\u53ef\u6bd4\u6027\uff0c\u5e76\u503e\u5411\u4e8e\u83b7\u5f97\u66f4\u597d\u7684\u6709\u6548\u7387\u3002<\/p>\n

\u4e2d\u56fd\u80ba\u764c\u7684\u53d1\u75c5\u7387\u53ca\u6b7b\u4ea1\u7387\u9ad8\u5c45\u764c\u75c7\u4e4b\u9996\uff0c2020\u5e74\u65b0\u53d1\u60a3\u8005\u7ea681.5\u4e07\u4eba\uff0c\u6b7b\u4ea1\u7ea671.4\u4e07\u4eba[1]<\/span><\/sup>\uff0c\u5176\u4e2dSCLC\u5360\u80ba\u764c\u768413~17%[2]<\/span><\/sup>\u3002SCLC\u60a3\u8005\u786e\u8bca\u65f6\u591a\u4e3a\u665a\u671f\uff0c\u9884\u540e\u6781\u5dee\uff0c\u4e94\u5e74\u751f\u5b58\u7387\u4ec57%\uff0c\u5e7f\u6cdb\u671fSCLC\u7684\u4e94\u5e74\u751f\u5b58\u7387\u4ec53%[3]<\/span><\/sup>\u3002\u5c3d\u7ba1SCLC\u5bf9\u4e8e\u521d\u59cb\u6cbb\u7597\u975e\u5e38\u654f\u611f\uff0c\u4f46\u5927\u591a\u6570\u60a3\u8005\u5728\u521d\u59cb\u6cbb\u7597\u540e\u51fa\u73b0\u8010\u836f\u53ca\u590d\u53d1\uff1b\u636e\u7edf\u8ba1\uff0c\u7ea675%\u7684\u5c40\u90e8\u665a\u671f\u60a3\u8005\u548c\u8d85\u8fc790%\u7684\u8f6c\u79fb\u6027\u60a3\u8005\u5728\u6cbb\u75972\u5e74\u5185\u590d\u53d1[4]<\/span><\/sup>\u3002SCLC\u7684\u9ad8\u590d\u53d1\u7387\u4e3a\u5176\u6cbb\u7597\u5e26\u6765\u5de8\u5927\u6311\u6218\uff0c\u4e34\u5e8a\u4e9f\u9700\u521b\u65b0\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n

\u9664\u4e86\u5728\u6fb3\u95e8\u5730\u533a\u83b7\u5f97\u4e0a\u5e02\u6279\u51c6\uff0c\u82a6\u6bd4\u66ff\u5b9a\u8fd8\u5206\u522b\u5728\u4e2d\u56fd\u5185\u5730\u548c\u9999\u6e2f\u5904\u4e8e\u4e0a\u5e02\u5ba1\u8bc4\u9636\u6bb5\uff0c\u5e76\u88ab\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u54c1\u79cd\u540d\u5355\u3002\u6b64\u5916\uff0c\u82a6\u6bd4\u66ff\u5b9a\u4ea6\u83b7\u5f97\u56fd\u5185\u5916\u591a\u4e2a\u6743\u5a01\u6307\u5357\u63a8\u8350\uff1a\u5305\u62ec\u300aNCCN\u5c0f\u7ec6\u80de\u80ba\u764c\u4e34\u5e8a\u5b9e\u8df5\u6307\u5357\uff082024.V1\uff09\u300b\u63a8\u8350\u8be5\u836f\u7269\u4f18\u5148\u7528\u4e8eCTFI\u22646\u4e2a\u6708\u7684SCLC\u60a3\u8005\uff0c\u300aCSCO\u5c0f\u7ec6\u80de\u80ba\u764c\u8bca\u7597\u6307\u53572023\u300b\u63a8\u8350\u5176\u4f5c\u4e3a\u22646\u4e2a\u6708\u6216\uff1e6\u4e2a\u6708\u590d\u53d1SCLC\u4e8c\u7ebf\u6cbb\u7597\u7b49\u3002<\/p>\n

\n\n\n\n\n\n\n\n
\n

\u53c2\u8003\u6587\u732e\uff1a<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[1]  International Agency for Research on Cancer \u2013 Population Fact Sheets \u2013 China. Available at https:\/\/gco.iarc.fr\/today\/data\/factsheets\/populations\/160-china-fact-sheets.pdf<\/a>. Accessed in December 2023.<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[2]  \u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\u6307\u5357\u5de5\u4f5c\u59d4\u5458\u4f1a. \u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u5c0f\u7ec6\u80de\u80ba\u764c\u8bca\u7597\u6307\u535720223. \u4eba\u6c11\u536b\u751f\u51fa\u7248\u793e. 2023<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[3]  Cancer.Net. Lung Cancer – Small Cell. Available at https:\/\/www.cancer.net\/cancer-types\/33776\/view-all. Accessed in December 2023.<\/span><\/p>\n<\/td>\n<\/tr>\n

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[4]  Rudin CM, et al. Nat Rev Dis Primers. 2021 Jan 14;7(1):3.<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n","protected":false},"excerpt":{"rendered":"

\u4e0a\u6d772023\u5e7412\u67084\u65e5 \/\u7f8e\u901a\u793e\/ — \u7eff\u53f6\u5236\u836f\u96c6\u56e2\u5ba3\u5e03\uff0c\u6ce8\u5c04\u7528\u82a6\u6bd4\u66ff\u5b9a\u5df2\u6b63\u5f0f\u83b7\u5f97\u4e2d\u56fd\u6fb3\u95e8\u836f\u7269\u76d1\u7763\u7ba1\u7406\u5c40\u7684\u4e0a\u5e02\u6279\u51c6\uff0c\u7528\u4e8e\u6cbb\u7597\u63a5\u53d7\u94c2\u7c7b\u836f\u7269\u5316\u7597\u671f\u95f4\u6216\u671f\u540e\u51fa\u73b0\u75be\u75c5\u8fdb\u5c55\u7684\u8f6c\u79fb\u6027\u5c0f\u7ec6\u80de\u80ba\u764c\uff08SCLC\uff09\u6210\u4eba\u60a3\u8005\u3002 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International Agency for Research on Cancer \u2013 Population Fact Sheets \u2013 China. Available at https:\/\/gco.iarc.fr\/today\/data\/factsheets\/populations\/160-china-fact-sheets.pdf. Accessed in December 2023. [2]  \u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\u6307\u5357\u5de5\u4f5c\u59d4\u5458\u4f1a. \u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u5c0f\u7ec6\u80de\u80ba\u764c\u8bca\u7597\u6307\u535720223. \u4eba\u6c11\u536b\u751f\u51fa\u7248\u793e. 2023 [3]  Cancer.Net. Lung Cancer – Small Cell. Available at https:\/\/www.cancer.net\/cancer-types\/33776\/view-all. Accessed in December 2023. 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